A University of Massachusetts Amherst team demonstrates a protein antigen from a childhood vaccine can be delivered into malignant tumor cells to refocus the immune system against cancer. The bacteria-based intracellular delivering system shows promise in treating pancreatic, liver, and metastatic breast tumors.
Researchers at the University of Massachusetts Amherst have developed a new method for DNA detection that is 100 times more sensitive than traditional methods. This breakthrough enables fast and accurate disease diagnosis, reducing wait times for lab processing from days to minutes.
Researchers at UMass Amherst have identified a small strand of microRNA called let-7 as crucial in governing the formation of cellular memories that enable T-cells to recognize and attack tumor cells. This discovery offers new insights into how vaccines work and could lead to improved cancer therapies by boosting cellular memory.
A new sensor design developed by a UMass Amherst-led team will monitor motion in stroke survivors' bodies to track their rehabilitation progress. The device uses wearable technology and the human body's conductive skin to transmit data, providing clinicians with valuable insights into patients' functional ability.
The UMass Amherst-UT Austin team has been awarded $27.5 million by the CDC to establish the nation's first disease outbreak response and modeling network. The $250 million program will support decision makers during public health emergencies like COVID-19.
A UMass Amherst neuroscientist is mapping the brain of a sea slug to study how neurons are added to functional neural circuits, shedding light on how this process contributes to neurological conditions. The project aims to provide an unprecedented look at brain development and potentially inform human brain development.
Researchers created a machine-learning algorithm using the largest data set of digital biomarkers for hot flashes. The predictive system delivers cooling to mitigate or fully alleviate hot flashes using Embr Wave's wearable device.
State-mandated school-based BMI assessments may help overweight students recognize their weight status but also lead to distorted self-image and body perception among non-overweight girls. The research found a small decrease in teens' BMI, primarily among those on the margin of being overweight.
A comprehensive global analysis found that these stop-smoking aids are nearly twice as effective as single forms of NRT. Dual forms of NRT, such as combining a patch with gum or a lozenge, were found to be nearly as effective as nicotine e-cigarettes and prescription medications.
Researchers at UMass Amherst have found evidence for evolutionary syndromes in wild tomatoes, which explain the development of their unique color, sweetness, acidity, and aroma. The study provides valuable insights into how fruits evolve in the wild and will be useful for breeding more nutritious and appealing varieties of fruits.
New research by UMass Amherst economist Brandyn Churchill links state-level 'SUNucate' laws to increased interest in sun protection, with a notable increase in sunscreen use among high school students. The legislation is associated with higher Google search volumes and awareness among historically low-users.
Researchers at UMass Amherst are investigating the connection between PFAS chemicals and breast cancer. They will examine data from postmenopausal women to determine if PFAS concentrations are associated with less breast tissue involution, which may increase breast cancer risk.
Researchers developed a liver-targeting drug that reversed obesity and lowered cholesterol in obese mice by delivering the drug via nanogel. The treatment, which was administered intraperitoneally, effectively normalized weight and reduced cholesterol levels despite continued high-fat diet consumption.
A new study from the University of Massachusetts Amherst found that the wealthiest 10% of Americans are responsible for 40% of the nation's total greenhouse gas emissions. The study suggests that policymakers adopt taxes focused on shareholders and the carbon intensity of investment incomes to equitably meet climate goals.
A University of Massachusetts Amherst kinesiologist is implementing a physical activity program for young children in preschools with low socioeconomic status. The pilot study aims to measure the impact on cognitive development and gross motor skills, with potential long-term implications for health disparities.
Researchers at UMass Amherst have discovered a potential new medical therapy for Lyme disease using lactate dehydrogenase inhibitors typically used to combat cancer. The study found that these inhibitors substantially impacted Borrelia burgdorferi growth, making them promising candidates against Lyme infections.
A new UMass Amherst study aims to develop a more robust understanding of the effects of ambient air pollution on women's reproductive health. The researcher will analyze data from 1,228 participants to identify mechanisms and susceptible reproductive processes across the menstrual cycle and early pregnancy.
A UMass Amherst biostatistician is developing statistical tools to better predict breast cancer survival rates and survival time after recurrence. The methods, funded by an NIH grant, will also have a broad application for other chronic diseases, such as those involving hormones and biomarkers.
Researchers have discovered a new phase of matter called the chiral bose-liquid state, which has surprising characteristics, such as robust spin and long-range entanglement. This discovery opens up new possibilities for understanding the physical world and potentially leading to breakthroughs in quantum computing.
A University of Massachusetts Amherst researcher has updated the Pregnancy Physical Activity Questionnaire (PPAQ), a widely used tool for measuring prenatal physical activity. The new PPAQ is considered reliable and valid, providing estimates of physical activity and sedentary behavior in pregnant women.
Researchers discovered that oxalic acid helps create a sticky, gel-like extracellular matrix in fungi and bacteria. The more oxalic acid present, the more viscous the matrix becomes, allowing microbes to control nutrient uptake and resistance to antibiotics.
A University of Massachusetts Amherst food science major compared the nutritional values of plant-based and dairy yogurts, finding almond milk yogurt has a significantly higher nutrient density. Plant-based yogurts generally have less total sugar, sodium, and fiber than dairy, but less protein, calcium, and potassium.
The US has lost 57.6 billion tons of topsoil due to farming practices, but new research suggests no-till methods can drastically reduce erosion and extend fertility for centuries. No-till farming, currently practiced on 40% of Midwest cropland acres, can modelled to slow down soil loss.
A team of engineers at UMass Amherst has created a device that can continuously harvest electricity from humidity in the air using nanopores in materials. The 'generic Air-gen effect' allows nearly any material to be engineered for this purpose, offering a cost-effective and scalable solution.
A new study highlights the need for standardized terminology, educational materials, and validated taste assessment methods to support cancer patients with taste loss. Clinicians' lack of knowledge about this issue can lead to poor patient care and outcomes.
A new randomized, controlled trial aims to integrate nutritional counseling with food-generating activities among people with HIV and food insecurity in the Dominican Republic. The project seeks to reduce viral loads, increase ART adherence, and improve overall health outcomes.
A UMass Amherst study found that changing patterns of land use lead to increased runoff and decreased forested areas, resulting in higher stream flow and increased phosphorous and nitrogen concentrations. The research warns of impending water quality issues if urban planning does not implement sustainable land-use measures.
A video-based smoking cessation program developed by a University of Massachusetts Amherst researcher has helped nearly 40% of HIV-positive smokers in Nepal quit tobacco. The program, which includes 11 video sessions and is accessible via smartphone app, was found to be highly effective in promoting abstinence among participants.
Researchers at UMass Amherst characterized two types of surface water in hyperarid salars, which are crucial habitats for animals like flamingoes and vicuñas. The study helps manage these ecosystems by treating terminal and transitional pools differently.
Lutz Grossman aims to create a protein-rich food source using hydrogenotrophic bacteria, which require no agricultural inputs. His goal is to produce a sustainable alternative to traditional protein sources, addressing global food security concerns.
Researchers at UMass Amherst microbiologists have identified an enzyme involved in TB pathogen's survival and growth. The discovery offers a potential target for drug therapies for the deadly disease, which has few effective treatments and caused over 1.6 million deaths worldwide in 2021.
Scientists at UMass Amherst found that migrating birds burn high amounts of protein early in their flights, which then taper off as the duration increases. This discovery challenges previous assumptions about bird migration and fuels further research into the evolution of metabolism.
A UMass Amherst food scientist is developing designer tempeh using smart fermentation, transforming soybean meal into a high-quality, protein-rich plant-based alternative. The goal is to create a scientifically-targeted approach to produce nutritious and delicious tempeh, replacing animal meat.
Engineers at UMass Amherst invent bilayered fabric that traps warmth like polar bear fur, keeping wearer comfortable in cold temperatures. The fabric is also lightweight and efficient, making it a sustainable alternative to traditional insulation.
A new study found that sunflower pollen's spiny structure reduces infection of a common bee parasite by 81-94% and increases the production of queen bumblebees. The research also suggests that other flowers in the sunflower family may have similar disease-fighting powers.
Research at the University of Massachusetts Amherst shows that circadian disruption from jet lag can harm adult neurogenesis, which supports learning and memory. The study found that the Cryptochrome 1 gene regulates this process and that misalignment can lead to adverse health effects such as dementia and mental illness.
A new study published in Vector-borne and Zoonotic Diseases demonstrates that the serum of white-tailed deer blood is lethal to the Lyme disease bacterium, Borrelia burgdorferi. The researchers hope this discovery may lead to new strategies for preventing and treating Lyme disease.
Researchers at UMass Amherst have discovered that beneficial microbes in infant gut use nitrogen from human milk to support pediatric nutrition and development. The study provides new insights into the molecular underpinnings of these processes, which could lead to improved infant health around the world.
Scientists create wearable sensors using biodegradable nanowires that can detect various chemical tracers, including those associated with asthma and kidney disease. The breakthrough represents a new paradigm in electrical engineering, offering a sustainable alternative to traditional silicon-based nanowires.
A University of Massachusetts Amherst epidemiologist is leading a team to better understand the effects of chronic stress on future health risks. They will examine metabolites in blood samples from a large, racially diverse population to identify potential biomarkers for heart disease, diabetes and cognitive decline.
An international team of researchers has created a detailed genetic map of two sea turtle species, revealing surprising similarities and differences. The study finds that green turtles have evolved more immune-related genes, while leatherbacks have historically lower population levels and reduced genetic diversity.
Researchers developed BirdFlow, a predictive model that utilizes eBird data and machine learning to forecast migratory patterns. The model was tested on 11 species of North American birds and found to outperform other models in tracking migration flows.
A new research project aims to promote dual-language development for children with autism in bilingual families. The study will examine the type of bilingual environment and factors related to their ability to speak or understand both languages.
A team from UMass Amherst developed an all-fabric pressure sensor that works even under pressure, allowing for long-term data gathering on health indicators like bone density and depression. The sensor can be worn in comfortable clothing, providing fine-grained details for remote detection of disease or physiological issues.
A team of researchers found that coastal habitats can adapt to rapid sea-level rise by utilizing abundant sediment, which can help salt marshes survive. The study's key finding highlights the importance of re-infusing sediment into estuary systems when dredging is necessary.
The implementation of the Affordable Care Act led to a significant reduction in uninsured adults under 65 with schizophrenia, from 8.4% to 4%. Medicaid coverage increased by 70%, while Medicare and private insurance coverage also rose.
Research identifies significant barriers in ER care for patients with mental health and substance use disorders, including emotional, diagnostic, and logistical challenges. Broad changes are needed to improve emergency care for this patient population.
A recent study found that soil microbes are releasing less CO2 in the summer due to decreased food availability, threatening their viability. However, autumn leaves mitigate this effect, but fewer dead leaves lead to a reduction in microbial biomass during the summer.
A UMass Amherst study reveals that 61% of wellness visits for reproductive-age women (15-49) were with OB-GYNs, while chronic condition patients also relied heavily on these specialists. Key preventive services like pap tests and pelvic exams were more common in OB-GYN settings, whereas lipid testing was rare.
A study published in Circulation found that walking between 6,000 and 9,000 steps per day significantly lowers the risk of a cardiovascular event in older adults. For those who are least active, even small increases in daily step count can have a substantial impact on heart health.