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University of Southern California


USC human speech study

USC researchers have developed a new technique using real-time MRI to capture the intricacies of human speech. The innovation allows for high-resolution movies of the vocal system, enabling better understanding of sound overlap in spoken language.

SourceUniversity of Southern California·JournalThe Journal of the Acoustical Society of America·DateApr 20, 2004

Evolution's twist

A USC study found that human ancestors developed meat-tolerant genes to resist diseases associated with a meat-rich diet, leading to slower aging and longer lifespan. However, the researchers argue that modern-day humans' sedentary lifestyle and lack of moderation may be contributing factors to high cholesterol and vascular disease.

SourceUniversity of Southern California·JournalThe Quarterly Review of Biology·DateMar 19, 2004

Cell shocked

Researchers at USC's Viterbi School have developed a new electric pulse technology called electroperturbation, which exposes cells to brief and intense electric pulses that can trigger cell death. The technique has advantages over conventional treatments, being non-invasive and able to deliver treatment remotely.

USC researchers produce a hairier mouse

Researchers at USC have created a transgenic mouse with an overexpressed noggin gene, resulting in increased hair follicles, thicker fur, and additional whiskers. The study also reveals unusual changes to the mice's eyes, feet, and genitalia, challenging the distinction between normal and abnormal variations.

SourceUniversity of Southern California·JournalAmerican Journal Of Pathology·DateFeb 23, 2004

Small and deadly

Researchers have made detailed measurements showing that the smallest particles are the most toxic, easily flowing into the lungs and coating moist tissue. The findings raise concerns about current national air quality standards for particulate matter, which have been linked to 60,000 smog-related deaths in the US each year.

On the tip

USC neuroscientist Emily Liman founds that calcium acts as a bridge for taste cells to send signals to the brain about what's been tasted. The study reveals new details on how the sense of taste works and could lead to the development of better artificial sweeteners or additives.

SourceUniversity of Southern California·JournalProceedings of the National Academy of Sciences·DateDec 9, 2003

The name of the game

Researchers analyzed data from twin pairs to find a link between leisure activities and reduced cognitive impairment. The study found that greater overall participation in intellectual-cultural activities, such as reading or joining clubs, was associated with a lower risk of Alzheimer's disease.

The key in the catalyst

Researchers discover new method to produce acetic acid directly from methane, reducing production costs and environmental impact. The breakthrough uses a palladium-based catalyst, but further development is needed to achieve commercial viability.

HRT fails to stall atherosclerosis in postmenopausal women with pre-existing coronary artery lesions

A recent study published in NEJM found that hormone replacement therapy does not effectively slow down the progression of atherosclerosis in postmenopausal women who already have cardiovascular disease. The study suggests that estrogen and progestin may not be effective in treating established coronary artery disease.

SourceUniversity of Southern California·JournalNew England Journal of Medicine·DateAug 6, 2003

The matrix, seismically loaded

Scientists tested a synthetic earthquake on a half-real building with conventional and simulated steel support columns. The experiment, called the 'Multi-Site Online Simulation Test,' used grid-linked machines to create a realistic simulation of an earthquake, producing a profusion of real-time data.

Translate this!

Researchers at USC's Information Sciences Institute built a state-of-the-art machine translation system for Hindi in less than a month, achieving all aspects of the DARPA's 'Surprise Language' project. The system uses statistical models to find the most likely translations and can query Hindi databases using English questions.

Getting closer

Researchers at USC successfully simulated the somatic hypermutation process in vitro, closely mirroring its natural occurrence. This breakthrough enables the development of an in vitro system that can mimic the body's immune response.

Of mice and memory

Researchers at USC developed synthetic enzymes that can combat oxidative damage, leading to improved memory in mice. The findings suggest these compounds may be more effective than traditional antioxidants in humans and could potentially treat various diseases with an oxidative component.

SourceUniversity of Southern California·JournalProceedings of the National Academy of Sciences·DateJun 25, 2003

New FPGA program techniques kick 'but'

Researchers at the University of Southern California have developed new FPGA programming techniques that can automatically translate programs into pipelined designs and optimize software for fixed-property chips. This allows for a low-cost, high-speed bridge from existing application software to FPGA platforms, reducing design time by ...

The structure behind the switch

USC researchers have discovered the molecular mechanism behind immunoglobulin class switching, which enables antibodies to adapt to different areas of the body. The study reveals that an R-loop forms between the DNA and RNA strands, creating a stable bond that determines the cut point for DNA splicing.

SourceUniversity of Southern California·JournalNature Immunology·DateApr 6, 2003

On the nose

A new USC study suggests that humans lost the ability to detect pheromones due to a gene essential for vomeronasal organ function. The study found that mutations in this gene occurred around 40 million years ago, leading to the disappearance of the gene and subsequent loss of vomeronasal organ function in primates.

SourceUniversity of Southern California·JournalProceedings of the National Academy of Sciences·DateMar 3, 2003