Articles tagged with Cancer Treatments
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A recent US study found that women with obesity have a significantly higher risk of death compared to those with normal weight. The study, which analyzed data from 90,185 women over seven years, showed that the risk of death increases substantially with increasing weight categories.
A study by USC researchers identified a protein called EphB4 that protects tumor cells from the immune system. Turning off this protein could make cancer cells more vulnerable to attack, and future therapies may aim to block its function.
A study by Thomas Denberg and colleagues found that fear, misconceptions, and anecdotal information significantly influence men's treatment decisions. Despite receiving health information, patients often struggle with recalling risks and benefits, leading to poor treatment choices.
A study across 5 Norwegian departments found that anti-TNF treatments worked better in patients with PsA and AS compared to RA. The combination of anti-TNF and MTX was shown to improve adherence and outcomes in these groups, while monotherapy was more effective for RA patients.
A study by Vahakn B. Shahinian and colleagues found that urologist input significantly influences the use of hormone therapy for prostate cancer patients, with up to 21% of variance attributed to their decisions. This suggests that urologists can be targeted for interventions to modify treatment recommendations.
The new technology allows for standardized, electronic reports after surgeries, improving data analysis and patient outcomes. It has been adopted by the Alberta Cancer Board and other health regions, tracking surgical effectiveness and resource allocation.
CS-Keys, a new company formed by Indiana University faculty, is developing an early diagnostic tool for breast cancer using a biomarker that distinguishes healthy cells from cancerous cells. The technology has the potential to improve diagnosis and treatment outcomes, making it easier to detect cancer in its earliest stages.
A new 'roulette wheel' tool can help patients visualize the risks and benefits of prostate cancer screening, allowing them to make more informed decisions. The tool presents probabilities in a clear and accessible way, helping patients weigh the potential benefits against the risks.
Researchers report improved survival rates with RP101, a novel compound being investigated as a potential therapeutic for advanced pancreatic cancer. In two studies, patients showed significant improvements in median survival and time to progression, offering hope for patients affected by the disease.
The study found that the average time to disease progression was approximately eight months for patients taking dexamethasone alone, while those on the Thal/Dex regimen had an average progression time exceeding 17 months. Researchers also reported more frequent side effects with the combination therapy.
The 2nd IOF Women Leaders Roundtable emphasizes the need for global awareness and action on osteoporosis. The participants urge individuals to engage in bone-friendly lifestyles and healthcare professionals to improve their knowledge about osteoporosis, while governments are encouraged to recognize it as a health priority.
The ASCO and ESMO have released a consensus statement outlining 10 essential components of quality cancer care, aiming to address inequalities in healthcare systems worldwide. The document highlights the importance of informed consent, multidisciplinary care teams, and access to innovative treatments for patients diagnosed with cancer.
A study in Queensland, Australia found that Indigenous patients had lower survival rates and fewer cases of early-stage cancer compared to non-Indigenous patients. The researchers highlight the need for holistic and culturally respectful approaches to address these disparities.
A recent study found that patients with genital HSV-2 infection who knew they had the virus and informed their partners were about half as likely to transmit the virus. The study suggests testing and disclosure as effective tools to prevent HSV-2 transmission, along with suppressive antiviral therapy and condom use.
Researchers have identified new biomarkers that correlate with patient response to anti-TNFá therapy, improving the treatment of spondylarthritis. The study found changes in synovial tissue features, such as macrophage and PMN cell changes, associated with disease activity and treatment effectiveness.
Researchers at Stanford University School of Medicine have made significant progress in developing RNAi gene therapy, a promising approach to treating organ-wide diseases. However, they also encountered unexpected side effects, including liver toxicity in mice, which hindered their progress. Despite this setback, the team was able to o...
Researchers found that men with the same hemoglobin levels before treatment experienced significantly different overall and progression-free survival depending on whether they were black or white. Anemic blacks fare worse than anemic whites, while blacks with high baseline hemoglobin fare better.
Research presented at Digestive Disease Week 2006 highlights current trends and advancements in GI cancers, clinical studies, and lifestyle choices. The meeting showcases more than 5,000 abstracts on the latest advances in GI research, medicine, and technology.
Researchers found that women who gained more than 60 pounds during adulthood were almost twice as likely to have ductal type tumors and more than 1.5 times more likely to have lobular type cancers. The risk for metastatic disease increased with weight gain, particularly among those who gained over 60 pounds.
Researchers at Stanford University have uncovered a novel mechanism of the tumor suppressor ING2, which regulates gene expression programs to prevent cancer formation. The findings highlight a new approach to understanding DNA damage responses in normal cells and potential therapeutic targets for cancer prevention and treatment.
A new study from the University of Michigan finds that patients often struggle to access reliable medical information online. Librarians play a crucial role in helping patients find quality resources, providing expertise and accessing specialized databases not available to the general public.
A new professorship in melanoma research has been established at the Cross Cancer Institute in Edmonton, Alberta. The endowment fund, valued at $1 million, will support long-term commitment to researching key pathways in melanoma development that could lead to potential targets for prevention and therapy.
A study of 403 premenopausal women with estrogen receptor-positive breast cancer found that increased Pak1 expression correlates with reduced sensitivity to tamoxifen therapy, leading to decreased survival rates. Researchers suggest targeting Pak1 as a potential strategy to improve treatment response in breast cancer.
In-vivo gene therapy has successfully restored immune function in three out of four dogs treated for XSCID. The treatment approach eliminates the need for ex-vivo cell manipulation and culture, potentially reducing adverse side effects and improving long-term efficacy.
Researchers discovered a novel compound, PI-103, that cooperatively inhibits both p110α subunit of PI3 kinase and downstream molecule mTOR. This dual inhibition shows high effectiveness against human gliomas in mice without toxicity.
Researchers have developed a completely penetrant mouse model of head and neck squamous cell carcinoma, recapitulating the human disease at both pathological and molecular levels. The model enables testing of combinations of targeted therapies and prevention approaches for HNSCC.
Researchers have discovered that C-myc, known as an oncogene, acts downstream of IL-15 signaling to regulate T memory cell homeostasis. This finding has implications for future therapies and highlights the importance of preserving a gene's role in normal processes.
A new study by Fox Chase Cancer Center reveals specific defects in RNA translation underlie a progressive disease called dyskeratosis congenita, linked to anemia, immune deficiency, cancer, and premature aging. The research highlights the importance of proteomic analysis and potential therapeutic targets for developing treatments.
Researchers found that follow-up PET scans showed persistent tumor activity in seven out of eleven RFA treatments. This suggests that FDG-PET is a more accurate method for evaluating tumor destruction than CT alone.
A recent mouse study led by the Salk Institute has discovered that healthy copies of the IL2RG gene used in X-linked severe combined immune deficiency (X-SCID) gene therapy can promote cancer development. One-third of mice treated with the gene developed lymphoma later in life.
A study of 797 breast cancer survivors found that only 33% received a mammogram each year over the five years after treatment. Regular mammography for breast cancer survivors declines steadily within five years of treatment, highlighting the need to increase awareness among healthcare providers and patients.
A national survey of 954 adults found that 44.7% of African-Americans and 33.5% of whites reported low trust in healthcare providers. Understanding these differences can help physicians improve trust and medical care for diverse patient communities.
Researchers have made progress toward a new form of light-activated gene therapy for cartilage repair, which is safe and compatible with existing surgical techniques. The therapy uses UV light to target specific cells and promote tissue growth, offering hope for treating knee injuries and potentially other conditions.
Researchers identified an intrinsic pathway involving PTEN that regulates stem cell transitions between quiescence and activity. Disrupting PTEN leads to increased active cycling and loss of quiescent stem cells, hindering long-term maintenance.
Researchers have found cancer cells suppress entire chromosome bands through epigenetic changes, silencing genes that prevent tumor growth. The discovery could lead to new treatments targeting DNA demethylation.
Researchers discover the structure of the WRN exonuclease domain, revealing its role in repairing DNA damage and maintaining genomic integrity. The study sheds light on the mechanisms underlying Werner's syndrome, a rare inherited disease that accelerates aging.
A study of over 39,000 women found that hormone therapy reduced the risk of heart attacks by 32% for those starting treatment in their 50s. However, the risk increased in older women within the first year of treatment before it decreased after two years.
A study of 25,719 women found that five-year cancer survivors reported functional limitations, such as heavy household work and mobility issues. The authors highlight the need for interventions to prevent and reverse functional decline among elderly long-term cancer survivors.
Scientists have successfully reversed cell division, a process essential to life, and may use this discovery to control cancer development and metastasis. The research holds promise for preventing and treating birth defects and other conditions.
Researchers found that combining a PI3K inhibitor with Herceptin can reverse lack of response in HER2-positive breast cancer patients. The addition of a PI3K inhibitor showed significant benefit in halting tumor growth, especially in tumors lacking PTEN protein.
Researchers found that omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) inhibited the growth of liver cancer cells, whereas omega-6 fatty acid arachidonic acid (AA) had no effect. The compounds induced apoptosis and decreased beta-catenin levels, which are involved in tumor progression.
Dasatinib has shown promise in treating leukemia patients resistant to standard therapies, with 93% complete hematologic response and 45% major cytogenetic response. However, relapses have occurred in certain patient groups due to dasatinib-resistant BCR-ABL mutations.
Researchers report three cases of advanced cancers with long survival times after high-dose intravenous vitamin C therapy. The study suggests that high-dose intravenous vitamin C should be reassessed as a potential cancer treatment option.
Research reveals that men's concerns about controlling their cancer drive treatment choices, despite limited reliance on scientific evidence. The study highlights the need for improved patient education and informed decision-making support.
A study by U-M researchers found that patients with delayed surgery (more than 93 days) had worse survival rates and lower three-year survival rates compared to those with timely surgery. Scheduling issues were the most common cause of delay, which can lead to micrometastases and poor outcomes.
A new study found that weight training significantly improved the quality of life for breast cancer survivors, reducing symptoms such as depression and anxiety. The exercise program also increased lean body mass and upper body strength.
The European School of Oncology task force recommends a multidisciplinary approach to managing metastatic breast cancer, prioritizing patient psychological wellbeing and disease-specific treatment goals. Patients with MBC should be offered psychosocial support and involved in decision-making.
A breakthrough project in the Netherlands dramatically improved patient care for breast cancer patients by implementing structured best practices. The initiative reduced waiting times to under a week and increased pre-operative multidisciplinary consultations, leading to more clear-cut diagnoses and fewer unnecessary operations.
Tadatsugu Taniguchi is honored with the international award for his major scientific discovery in basic cancer research, elucidating cytokine gene families and transcription factors. He made significant contributions to our understanding of immune defense mechanisms and cancer therapy.
The UK Biobank project is a revolutionary research undertaking that will gather and store vast amounts of medical data from 40,000 to 69-year-old volunteers. Researchers hope to identify more reliable reasons for why some people develop specific diseases and others do not.
A study identifies molecular subclasses of high-grade gliomas that correlate with disease progression and prognosis. The subtypes resemble stages in neurogenesis, suggesting new insights for therapeutic intervention.
Researchers found that Aldara Cream reduced fine lines and wrinkles, improved skin texture, and enhanced color in prematurely aged skin. The cream showed significant improvements in 80% of the subjects, with 90% expressing strong approval.
The Australian government has pledged $50 million to support the expansion of the Walter and Eliza Hall Institute's (WEHI) research capabilities in cancer and infectious disease. This funding will enable significant expansions in the institute's research programs, focusing on targeted therapies for cancer treatment and malaria control.
A study found that internet use increases feelings of control among cancer patients, allowing them to view their relationship with doctors as a partnership. Online access also enables patients to make informed decisions about their treatment.
A study suggests that delayed surgical intervention can be a safe alternative to immediate treatment for men diagnosed with early-stage, low-grade prostate cancer. The research found equivalent risks of noncurable prostate cancer in both groups, depending on factors like age and PSA levels.
A study by the North Central Cancer Treatment Group found that reducing epoetin alfa dosing frequency from once weekly to every three weeks did not significantly impact hemoglobin levels or require transfusions. Patients in both treatment groups reported similar quality of life at the end of the 21-week study.
Researchers found a substantial link between severe rheumatoid arthritis and increased risk of lymphoma. Patients with high RA activity experienced a 70-fold increase in lymphoma risk, while those with low activity had an 8-fold increase.
Experts warn that sharing study results with participants could negatively impact their future health due to potential regret over less effective treatments. A revised informed consent strategy is proposed to balance individual rights with the need for transparency.
Researchers found that a common osteoporosis treatment helped men with prostate cancer recover significant bone mass after two years of androgen deprivation therapy. The study suggests that bone density tests should be encouraged for men at risk, and bone-preserving therapy could prevent debilitating fractures.
A recent study by Dr. Elizabeth Krall Kaye found that cigarette smokers are 70% more likely to need root canal treatment than nonsmokers. Quitting smoking is linked to a lower risk of needing the procedure.