Articles tagged with Clinical Trials
Researchers will test two forms of secretin on 51 children with autism, aged 3-12, to evaluate its effectiveness. The trial aims to uncover the genetic and neurobiological causes of autism and identify potential side effects.
Researchers use functional magnetic resonance imaging (fMRI) to study children's brain development and identify language centers. The non-invasive test shows that children as young as 7 years old rely on the left hemisphere for language, similar to adults.
A three-year exercise program significantly lowered mortality rates among men who had suffered a heart attack. The study found that increased physical work capacity during the trial period was associated with reduced risk of death at every time period.
A large clinical trial of mechanical ventilator use for intensive care patients with Acute Respiratory Distress Syndrome (ARDS) has been stopped early due to the success of a smaller breath strategy. This approach was found to reduce deaths by approximately 25 percent, improving the care and saving thousands of lives each year.
A clinical trial testing tin-117m DTPA, a nuclear medicine compound, may provide non-sedating pain relief and treatment for advanced-stage bone cancer. The therapy has shown promising results in easing pain for over 75% of patients, with relief lasting up to a year.
The Azithromycin and Cardiac Events Study (ACES) investigates the role of Chlamydia pneumoniae in atherosclerosis. Researchers aim to determine if antibiotics can prevent complications of coronary artery disease, enrolling approximately 4,000 volunteers.
A clinical trial testing Azithromycin's effectiveness in preventing recurrent heart attacks found a promising link between the antibiotic and reduced inflammation. Researchers aim to determine if treating patients with Azithromycin for five days after an initial heart attack can prevent future heart attacks.
Patients with congestive heart failure who exercised had higher survival rates after four years compared to those who did not, with a 92% versus 64% rate of survival. The study's findings support the potential benefits of exercise for patients with this condition and underscore the need for further research.
The US Department of Energy's Brookhaven National Laboratory is offering a new clinical trial for brain tumor patients, including those whose cancer is inoperable or has regrown. The trial aims to increase the radiation dose and expand eligibility requirements for glioblastoma multiforme patients.
A Cedars-Sinai Medical Center clinical trial may offer a permanent, non-surgical cure for patients with Paroxysmal Atrial Fibrillation. Correctly identifying patients and eliminating trigger areas using radiofrequency energy could eliminate the need for long-term therapy and reduce stroke risk.
A study of over 2,000 American women who underwent medical abortion with mifepristone and misoprostol found that the method was highly effective and satisfactory, even among those for whom it failed. Women preferred the non-invasive nature and natural experience of the method, and reported few side effects.
A nationwide clinical trial involving nearly 400 patients showed no statistically significant difference in full recovery and mortality rates between those given citicoline and a placebo. However, the drug appeared to produce an improvement in a subset of patients with moderate to severe strokes.
A national trial is underway to determine the effectiveness of removing portions of lungs in patients with severe emphysema. The study aims to find out if the procedure improves long-term outcomes and reduces complications for patients with this debilitating disease.
The BERT-1 trial found that low-dose beta radiation effectively prevents restenosis by reducing late lumen loss in coronary arteries. In a six-month follow-up, 90% of patients experienced no significant narrowing of their vessels post-angioplasty.
A new analysis of 18 clinical trials found low-dose diuretic therapy to be highly effective in reducing the risk of stroke, congestive heart failure, coronary disease, and total mortality in patients with high blood pressure. Beta blockers also showed promise in preventing these complications.
A new University of North Carolina at Chapel Hill study reveals that women with non-ischemic heart failure have a significantly higher survival rate than men, even after accounting for differences in age and other factors. In contrast, men with ischemic heart failure were more likely to die prematurely.
A Cornell University scholar reexamines the Nuremberg Medical Trial, highlighting the use of a fictional report to justify medical research on US prisoners. The paper also critiques Andrew Ivy's testimony at the trial and its implications for the field of medical ethics.
A five-center trial shows partial liquid ventilation is safe and effective, improving lung function and increasing survival chances for critically ill premature infants. The procedure involves introducing oxygen-rich liquid into the lungs, reducing pressure damage and improving oxygen exchange.
A meta-analysis of 165 clinical trials shows women and men respond equally to drug treatments, challenging traditional recognition of heart disease in women. The study's findings have implications for policy makers and treatment protocols.
Researchers at Duke University Medical Center report a genetically modified version of hemoglobin as a safe blood substitute during surgery. The product, rHb 1.1, is designed to carry oxygen efficiently and eliminate disease transmission and immunosuppression, potentially reducing medical costs for patients and hospitals.