Wistar scientist awarded American Cancer Society grant for research on tumor killing cells
Dr. Daniela Santoli to develop TALL-104 regimen for effective and safe treatment of metastatic melanoma patients; trials expected to start later this year.
Clinical Trials
Articles tagged with Clinical Trials
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Scientific Trials Of So-Called 'Wonder' Hormone Treatment For Autism Will Be Conducted In Seattle, Denver
Researchers will test two forms of secretin on 51 children with autism, aged 3-12, to evaluate its effectiveness. The trial aims to uncover the genetic and neurobiological causes of autism and identify potential side effects.
Nonintrusive Imaging Technique Useful For Identifying Language Regions In Kids' Brains
Researchers use functional magnetic resonance imaging (fMRI) to study children's brain development and identify language centers. The non-invasive test shows that children as young as 7 years old rely on the left hemisphere for language, similar to adults.
Improved Fitness Lowers Mortality Risk Of Male Heart-Attack Survivors
A three-year exercise program significantly lowered mortality rates among men who had suffered a heart attack. The study found that increased physical work capacity during the trial period was associated with reduced risk of death at every time period.
NHLBI Clinical Trial Stopped Early: Successful Ventilator Strategy Found For Intensive Care Patients On Life Support
A large clinical trial of mechanical ventilator use for intensive care patients with Acute Respiratory Distress Syndrome (ARDS) has been stopped early due to the success of a smaller breath strategy. This approach was found to reduce deaths by approximately 25 percent, improving the care and saving thousands of lives each year.
Promising Bone Cancer Therapy Advances To Next Level
A clinical trial testing tin-117m DTPA, a nuclear medicine compound, may provide non-sedating pain relief and treatment for advanced-stage bone cancer. The therapy has shown promising results in easing pain for over 75% of patients, with relief lasting up to a year.
National Clinical Trial To Test Effectiveness Of Antibiotic Treatment For Coronary Artery Disease
The Azithromycin and Cardiac Events Study (ACES) investigates the role of Chlamydia pneumoniae in atherosclerosis. Researchers aim to determine if antibiotics can prevent complications of coronary artery disease, enrolling approximately 4,000 volunteers.
Cardiac Clinical Trial Studies Use of Antibiotic In Preventing Heart Attack
A clinical trial testing Azithromycin's effectiveness in preventing recurrent heart attacks found a promising link between the antibiotic and reduced inflammation. Researchers aim to determine if treating patients with Azithromycin for five days after an initial heart attack can prevent future heart attacks.
Exercise May Lengthen Life In Patients With Congestive Heart Failure
Patients with congestive heart failure who exercised had higher survival rates after four years compared to those who did not, with a 92% versus 64% rate of survival. The study's findings support the potential benefits of exercise for patients with this condition and underscore the need for further research.
Brain Tumor Patients Offered New Hope With Expanded Trial Of Promising Therapy
The US Department of Energy's Brookhaven National Laboratory is offering a new clinical trial for brain tumor patients, including those whose cancer is inoperable or has regrown. The trial aims to increase the radiation dose and expand eligibility requirements for glioblastoma multiforme patients.
Clinical Trial May Provide Cure For Patients With Paroxysmal Atrial Fibrillation
A Cedars-Sinai Medical Center clinical trial may offer a permanent, non-surgical cure for patients with Paroxysmal Atrial Fibrillation. Correctly identifying patients and eliminating trigger areas using radiofrequency energy could eliminate the need for long-term therapy and reduce stroke risk.
Early Medical Abortion With Mifepristone (RU 486) And Misoprostol Is Highly Acceptable To American Women
A study of over 2,000 American women who underwent medical abortion with mifepristone and misoprostol found that the method was highly effective and satisfactory, even among those for whom it failed. Women preferred the non-invasive nature and natural experience of the method, and reported few side effects.
Oregon Health Sciences University Researcher Presents Results Of Clinical Trials Of Possible Stroke-Fighting Drug
A nationwide clinical trial involving nearly 400 patients showed no statistically significant difference in full recovery and mortality rates between those given citicoline and a placebo. However, the drug appeared to produce an improvement in a subset of patients with moderate to severe strokes.
National Trial Begins For Controversial Lung Surgery For Emphysema
A national trial is underway to determine the effectiveness of removing portions of lungs in patients with severe emphysema. The study aims to find out if the procedure improves long-term outcomes and reduces complications for patients with this debilitating disease.
Zapped Arteries Remain Largely Clean And Clear Six Months Postangioplasty, Per BERT-1 Results
The BERT-1 trial found that low-dose beta radiation effectively prevents restenosis by reducing late lumen loss in coronary arteries. In a six-month follow-up, 90% of patients experienced no significant narrowing of their vessels post-angioplasty.
Analysis Of Clinical Trials Yields New Appreciation Of Low-Dose Diuretic Therapy For High Blood Pressure
A new analysis of 18 clinical trials found low-dose diuretic therapy to be highly effective in reducing the risk of stroke, congestive heart failure, coronary disease, and total mortality in patients with high blood pressure. Beta blockers also showed promise in preventing these complications.
Study: Heart Failure Kills Men Faster Than Women
A new University of North Carolina at Chapel Hill study reveals that women with non-ischemic heart failure have a significantly higher survival rate than men, even after accounting for differences in age and other factors. In contrast, men with ischemic heart failure were more likely to die prematurely.
Nuremberg Medical Ethics Reexamined
A Cornell University scholar reexamines the Nuremberg Medical Trial, highlighting the use of a fictional report to justify medical research on US prisoners. The paper also critiques Andrew Ivy's testimony at the trial and its implications for the field of medical ethics.
Partial Liquid Breathing Improves Lung Function, Chances of Survival in Sick Preemies
A five-center trial shows partial liquid ventilation is safe and effective, improving lung function and increasing survival chances for critically ill premature infants. The procedure involves introducing oxygen-rich liquid into the lungs, reducing pressure damage and improving oxygen exchange.
Women And Men Respond Equally To Medical Treatment For Coronary Artery Disease
A meta-analysis of 165 clinical trials shows women and men respond equally to drug treatments, challenging traditional recognition of heart disease in women. The study's findings have implications for policy makers and treatment protocols.
Blood Substitute Found Safe During Surgery
Researchers at Duke University Medical Center report a genetically modified version of hemoglobin as a safe blood substitute during surgery. The product, rHb 1.1, is designed to carry oxygen efficiently and eliminate disease transmission and immunosuppression, potentially reducing medical costs for patients and hospitals.