Articles tagged with Brain Damage
Researchers used mass spectrometry to identify 10 differentially expressed proteins in the brain after acute high-altitude hypoxia. These proteins are involved in the electron transport chain and ATP synthase function, providing potential targets for treating hypobaric hypoxia-related brain injury.
Researchers have identified a potential new target for breast cancer treatment: ERBB3, an oncogene that promotes tumor growth. The study also found peritoneal dialysis to be effective in reducing brain damage after stroke by lowering glutamate levels.
The study found that Braintone increased the expression of hypoxia-inducible factor 1α, heme oxygenase-1 and vascular endothelial growth factor in ischemic cortex of rats with middle cerebral artery occlusion. This suggests a neuroprotective effect on ischemia-induced brain damage.
Researchers at SISSA uncover inconsistencies in the dependence of the linguistic system on the motor one, with damage to specific brain regions affecting gesture imitation but not language processing. The study employs voxel-based lesion symptom mapping to establish a link between brain damage and performance decline.
A 2.5-year-old boy with severe brain damage was treated with autologous cord blood and showed significant improvement in symptoms, including learning to speak simple sentences and move. The treatment's effectiveness has sparked hope for alternative therapies for infantile cerebral palsy.
A study by OK International and CREPD found high levels of lead in household paints sold in Cameroon, exceeding 50% by weight. The US company PPG is the manufacturer, despite lead being banned in the US for over 30 years.
Researchers at Northwestern University have made significant breakthroughs in understanding the effects of brain damage on language processing and recovery. Studies have shown that with targeted training, patients can regain speech abilities years after a stroke.
A Mayo Clinic study found that blood's tendency to clot may contribute to areas of brain damage called white matter hyperintensities, which can lead to memory problems and increased stroke risk. Women with higher levels of thrombogenic microvesicles were more likely to develop these changes.
A study using rodents found that binge-like drinking can cause damage to the hippocampus after 24 hours, indicated by increased expression of vimentin brain protein. Chronic drinking is known to have detrimental health effects, and this research provides new insights into the threshold for alcohol-induced brain damage.
A study suggests that linagliptin, a commercialized diabetes drug, can stimulate neuroprotection and largely reduce brain damage following stroke. This could lead to better prognosis for type 2 diabetic patients after a stroke.
A new study by UCLA researchers found that women with obstructive sleep apnea have more severe brain damage than men with the disorder. The study also revealed that women are more affected by sleep apnea and experience higher levels of depression and anxiety symptoms.
A Concordia University study has found that adults with mild cognitive impairment (MCI) are impaired in several aspects of executive functioning, particularly inhibitory control. The researchers hope their work will lead to the development of more reliable tools for detecting Alzheimer's disease at an earlier stage.
Researchers have developed a new experimental drug that reduces brain damage and improves motor skills in stroke-afflicted rodents. The drug, 3K3A-APC, extends the therapeutic window of tPA, allowing for more effective treatment beyond the three-hour time frame.
Researchers have designed a new chemical compound that binds 1,000 times more effectively to the target protein in the brain than current drugs, reducing cell death by 40% in animal models. The compound also improves motor function and passes through the blood-brain barrier.
Research reveals that drinking alcohol induces significant brain atrophy and specific shrinkage in cerebral cortex and thalamus in genetically vulnerable mice. The findings support the protective role of dopamine D2 receptors against alcohol-induced brain damage.
Researchers report successful early transplantation of human placenta-derived mesenchymal stem cells into neonatal rats with birth-related brain damage, detecting neurologic improvement.
Repeated head trauma in hockey players causes irreversible brain damage and a condition called CTE. Experts urge a ban on intentional head trauma and severe deterrent penalties to protect player health.
New research reveals that Toll-like receptors play a major role in brain damage risk for newborns, contributing to conditions like cerebral palsy and epilepsy. The discovery could lead to more effective treatment strategies, such as blocking special TLRs to reduce brain damage following hypoxia.
A Mayo Clinic study provides guidance for treating sudden cardiac arrest patients with therapeutic cooling, which slows metabolism and preserves cell health. The study found that both patient groups awoke within three days, supporting the use of hypothermia when indicated.
Researchers at Scripps Research Institute discovered that fetal brain damage from oxygen deprivation is linked to the action of a fatty molecule called LPA, which can be targeted with drugs. This finding provides a new strategy to limit or prevent serious developmental brain diseases.
A new device measures brain temperature non-invasively, allowing for more precise cooling therapies in infants and adults, with potential to reduce brain damage and death.
A new study uses creative engineering to unravel brain mechanisms associated with self-consciousness, identifying the TPJ as critical for self-location and first-person perspective. The research found that brain damage interfering with multisensory body information may lead to pathological changes in these subjective states.
A new study sheds light on the complex process of recovery from aphasia after a stroke, finding that inter-hemispheric coordination plays a crucial role. The research suggests that the involvement of both hemispheres in language functions is not as binary as previously thought.
Researchers found that stroke patients with severe motor impairments used alternative mental strategies to complete tasks, suggesting a more complex phenomenon than previously thought. The study suggests that motor imagery may be a key factor in creative problem-solving and innovation.
Researchers identified TRPC6 as a key player in ischemic nerve cell death and found that suppressing its degradation prevents brain damage. In a rat model of stroke, they demonstrated that inhibiting TRPC6 degradation reduces nerve cell death.
A new study published in Neurology found that mentally active lifestyles may reduce the negative effects of brain damage on learning and memory in people with multiple sclerosis. Participants with enriching lifestyles showed better scores on tests of learning and memory despite higher amounts of brain damage.
A Mediterranean-like diet was found to be associated with a lower risk of brain infarcts and areas of dead tissue linked to thinking problems. Researchers assessed the diets of 712 people and found those who closely followed the diet were 36% less likely to have brain damage.
Patients with type 2 diabetes who experience subtle brain damage may be at risk of progressive kidney disease and kidney failure, according to a new study. Diabetic patients with silent cerebral infarction were nearly five times more likely to develop serious kidney disease than those without.
A new blood test can detect brain damage in amateur boxers, with nerve cell deterioration shown to persist even after a two-month break from boxing. The study's findings provide further evidence that repeated blows to the head may cause long-term brain damage.
A study has found that divers who hold their breath for several minutes have elevated levels of the protein S100B, which can signal brain damage. However, these levels are temporary and it remains unclear whether prolonged apnea can cause long-term brain damage.
A study published in Neurology found that people over 60 with high blood pressure are more likely to experience silent strokes. High blood pressure increases the risk by 60%, while white matter hyperintensities nearly double the likelihood of silent strokes.
A recent study published in Nature Medicine reveals that Treg cells limit brain damage after a stroke by blocking neurotoxin production and modulating lymphocyte and microglia action. This discovery offers potential treatments for preserving crucial functions and treating other types of brain damage.
A study by Chen et al. reveals that chopped-up ECM triggers excitotoxicity through the kainate receptor's KA1 subunit, leading to brain damage. Drugs blocking KA1 might provide an alternative way to save brain cells after stroke or head trauma without causing cognitive impairment.
Researchers demonstrate a blind man's ability to navigate an obstacle course without visual awareness, utilizing alternative brain routes. The study reveals the importance of these hidden pathways in everyday navigation and function.
Recent studies suggest that methylmercury can cause irreversible brain damage in unborn children at previously considered safe levels of exposure. Methylmercury toxicity is well-known, but its effects on the developing nervous system have been underestimated.
A woman with phonagnosia, unable to recognize her daughter's voice on the phone, undergoes tests that reveal difficulties in recognizing famous actors' voices but not other sounds or music. The study suggests there may be more people with similar conditions, and researchers seek contact from potential sufferers.
A recent study found high levels of IL-6 in affected individuals over a decade before nervous system symptoms began to manifest. This discovery challenges current understanding of the physiological basis of Huntington's disease and may lead to new early intervention strategies.
Scientists are using a powerful supercomputer to create a model of normal human language that can read, comprehend, and repeat basic words. The 'Chatter Box' project aims to understand how the brain supports language function and how it breaks down after brain damage.
The Hospital Clinic de Barcelona has been recognized for its expertise in detecting brain damage in fetuses, thanks to a multidisciplinary research group led by Dr. Eduard Gratacós. The award includes €1.2 million for further research on premature brain damage.
Despite progress, an estimated 1.6 billion people remain at risk of iodine deficiency disorders (IDD), with 38 million newborns worldwide still unprotected. Iodized salt can prevent IDD, which affects up to 20-25% of children in developing countries and can cause IQ loss and brain damage.
A study found that prazosin, an alpha-1 receptor antagonist, can block the increase of steroid hormones in the brain, which are associated with brain damage and cognitive impairment. This may provide a neuroprotective effect against post-traumatic stress disorder, Alzheimer's disease, depression, and schizophrenia.
Researchers at Kennedy Krieger Institute discovered separate adaptable networks controlling each leg and leg movements, e.g., forward or backward walking. This finding enhances understanding of motor skills and brain plasticity, signaling advancements for future rehab practices.
A recent study by OHSU and VAMC researchers found that female mice are more susceptible to brain cell death after alcohol withdrawal than male mice. The study suggests that women may be more vulnerable to the neurotoxic consequences of alcohol consumption, which could contribute to debilitating cognitive dysfunction and motor deficits ...
Research reveals that blows to the head in amateur boxing lead to elevated levels of biochemical markers for brain injury. A particular marker for neuronal damage, neurofilament light, was found to be four times higher in boxers after a fight compared to healthy non-athletes.
A new online book, 'When Grandpa Comes Home: A Story About Stroke,' is now available to help children understand the causes and effects of a stroke. The illustrated book, written by a student intern and artist, aims to reduce fear and uncertainty in kids who witness a family member's stroke.
Researchers found that listeners more quickly recognize verbs as genuine when they have a meaning related to the verb in the sentence. The activation of verbs follows the end of the main clause, whereas nouns remain active throughout the sentence.
Researchers have discovered a new protein called neuroglobin in the brain that defends against oxygen deprivation and brain damage. This protein plays a protective role, ushering in nitric oxide to protect neuron survival and recovery.
Scientists have identified special proteins that help repair and protect the brain after it has been damaged by a lack of oxygen. Dr Nicole Jones and her team found that these proteins increase during oxygen deprivation, regulating processes like red blood cell production and glucose flow to the brain.
A recent study published in Anesthesiology found that xenon was administered safely to patients undergoing coronary artery bypass grafting, showing its potential as a neuroprotectant. The discovery could lead to new treatments for conditions such as strokes and brain injuries, where nerve damage is a major concern.
Researchers found that blocking the nerve receptor EP1 significantly reduced brain damage in mice following stroke. The study suggests an alternative to COX inhibitors, which have lethal side effects.
A new study reveals that SARS can infect brain tissue, causing severe central nervous system symptoms. The researchers found a high level of Mig, an immune system regulator, in the patient's bloodstream and brain, which may contribute to brain damage.
Researchers identify signal in damaged brain that prevents cells from restoring lost myelin; HA accumulation linked to CD44 protein. Oligodendrocyte progenitors can be prevented from maturing into myelin-producing cells, while injection of HA into damaged myelin prevents reforming.
Researchers discovered that hyaluronic acid inhibits oligodendrocyte progenitor maturation, leading to brain damage. The findings offer clues on reversing some forms of brain damage and improving lives of thousands of infants.
A study found that doctors and caregivers often focus on physical and cognitive effects, but patients report additional challenges such as social isolation and self-consciousness. The research highlights areas that deserve more attention and suggests interventions like lip reading training and videos to improve patient recovery.
This study investigates the effects of alcohol on brain structure and function, highlighting permanent and transient changes due to excessive drinking. Abstinence has been shown to reverse some brain damage, including dendrite shrinkage, which may improve cognitive functions.
A new study published in Experimental Neurology found that rats fed diets rich in blueberries, spinach, or spirulina experienced less brain cell loss and improved recovery after a stroke. The antioxidant-rich diets may counteract the burst of free radicals involved in brain cell death triggered by an ischemic stroke.
Researchers have found that cooling can significantly reduce brain damage in newborn babies who suffer from oxygen deprivation at birth. The treatment involves lowering the body temperature of the baby for 72 hours after birth using a water-filled cap. This breakthrough discovery has the potential to bring routine treatment to babies s...
Research found that cigarette smoking accelerates brain damage in individuals with alcohol dependence, particularly in the frontal lobes. This can lead to compromised executive functions, problem-solving abilities, and emotional regulation. Chronic smoking also impairs neuronal viability and cell membranes in other brain regions.
A study found that community-based heavy drinkers have clear brain metabolite changes associated with lower brain function and are likely of behavioral significance. Brain damage is detectable even in those who function relatively well in the community.
A new study by Southern Methodist University researchers has found that nanoparticles, specifically buckyballs, can cause significant brain damage in fish within 48 hours. The study's lead author suggests further testing and assessment of the risks and benefits of these nanoparticles before their widespread use.