Articles tagged with Brain Damage
Research from the University of Waterloo and the University of Auckland found that stabilizing blood sugar levels in newborns with hypoglycemia prevents brain damage. Untreated low blood sugar can cause adverse effects on a child's neurodevelopment up to age 4.5 years old.
Researchers found a strong connection between retinal layer thickness and brain volume, suggesting retina assessments as a potential biomarker for brain atrophy. Thinner retinal layers correlated with reduced brain white matter and hippocampus volume.
Scientists demonstrate a definitive link between mitochondrial oxidative damage and cognitive dysfunction in Alzheimer's disease using a transgenic mouse model. The study found that Aβ1-42 aggregation in the hippocampus caused cognitive impairment, while oxidation led to mitochondrial dysfunction.
A new study from the University of Illinois reveals that nearly all soil samples in Chicago contain high levels of lead, with some areas reaching up to 3,000 ppm. The findings highlight the need for further monitoring and mitigation efforts to address environmental justice concerns.
A ketogenic diet has been shown to improve spatial memory and visual memory, lower brain inflammation indices, and cause less neuronal death in individuals with traumatic brain injuries. The diet may also slow down the rate of cellular aging, offering hope for those suffering from this condition.
A long-term study found that academic education can positively affect aging of the brain, with reduced degenerative processes and improved cognitive performance. Participants with an academic background showed a lower increase in signs of brain degeneration and faster processing speeds.
Researchers have designed a digital camera-based system that can accurately detect jaundice in newborns within one second, sending diagnoses to carers via SMS. The system uses image processing techniques to detect bilirubin levels, triggering blue LED phototherapy and treatment.
A study published in JAMA Neurology found that long-term exposure to space can cause brain damage in cosmonauts. The research analyzed five Russian male cosmonauts who spent an average of 169 days in space, showing significant increases in biomarkers for brain cell damage upon their return to Earth.
A widely used procedure to treat birth-related brain damage in newborn babies in low and middle income countries (LMICs) may increase the risk of death. The HELIX trial found that 50% of infants who received the cooling treatment died or had moderate or severe disability.
A new protein marker, neurofilament light protein (NFL), has been found to predict stroke severity and long-term outcomes. The levels of NFL in blood correlate with more severe brain damage and poorer survival rates after stroke.
Heidelberg researchers demonstrate that restoring VEGFD levels can preserve dendritic arborisation and reduce brain damage after a stroke. A treatment using recombinant VEGFD and nose drops achieved similar results in mouse models.
Scientists have identified a key brain region responsible for executive functions, including selective attention and working memory. The study found that damage to the inferior frontal junction area (IFJ) can lead to impairments in these abilities, as seen in individuals with dysexecutive syndrome.
A 30-year study on Crigler-Najjar syndrome reveals the clinical course of 28 individuals with high bilirubin levels, demonstrating the effectiveness of phototherapy and liver transplantation. Early intervention is critical, and treatment delays increase brain damage risk.
A Zika virus strain in northeastern Brazil was particularly damaging to the developing brain, causing microcephaly in over 80% of cases. Researchers found that this strain led to neurodegeneration and smaller brains, but other factors such as environmental viruses may have also played a role.
Researchers have discovered that chronic liver diseases can cause cerebral molecular disturbances as early as two weeks after liver malfunction, even without physical symptoms. The study found two new molecules involved in the disease process: creatine and vitamin C.
The M-RISE program aims to develop innovative therapies to prevent brain damage caused by cardiac arrest, with a focus on early treatments delivered by bystanders and first responders. The program will explore neuroprotective agents and strategies to improve survival rates and outcomes for patients affected by cardiac arrest.
Experts debate the effectiveness of electroconvulsive therapy (ECT) in treating severe depression, with some arguing it has no long-term benefits compared to placebo and can cause brain damage. Others claim ECT is effective and safe for treatment-resistant depression, with most side effects resolving within weeks.
A new blood test reliably detects signs of brain damage in people with Alzheimer's disease, even before symptoms of confusion and memory loss arise. The test may also identify neurodegeneration in other brain diseases, injuries, and conditions such as multiple sclerosis and traumatic brain injury.
A new 15-minute brain scan predicts damage with 98% accuracy, helping doctors assess the extent of newborn brain damage and plan for long-term development. The scan may also aid in developing new treatments for brain injury in babies.
Researchers have discovered a new and better marker, Neurofilament light (NFL), to assess the degree of brain damage after cardiac arrest. This biomarker shows promise in identifying patients with severe brain damage and could lead to more efficient healthcare decisions.
A new study from the University of Pittsburgh has identified arterial stiffness as a key risk factor for dementia in older adults. The researchers found that individuals with high arterial stiffness readings were 60% more likely to develop dementia over a 15-year period.
A new study published in Clinical Neurophysiology found that attention plays a key role in restoring vision in patients with hemianopia, a condition where half of the visual field is impaired. After five weeks of vision rehabilitation training, patients showed significant improvements in their visual function.
The Swiss Atrial Fibrillation Cohort Study found that 41% of atrial fibrillation patients had previously unknown brain damage, including cerebral infarcts, microbleeds, and lacunes. This brain damage may explain the association between dementia and atrial fibrillation in patients without prior stroke.
A clinical trial found that adrenaline increases the survival rate of patients with cardiac arrests by less than 1%, but almost doubles the risk of severe brain damage for survivors. The study raises questions about the future use of adrenaline in such cases and its impact on patient outcomes.
Researchers studied woodpecker brains for tau protein accumulation, a sign of brain damage in humans. The study suggests that the accumulation might be a protective adaptation rather than indicative of injury, which could have implications for human neurodegenerative diseases.
Dr. Olga Boukrina's research aims to identify high-risk patients with brain damage and type of reading difficulties after stroke, enabling early intervention. Her goal is to develop criteria for effective interventions to help stroke survivors regain their reading ability.
Fetal monitoring specialists argue that continuous electronic monitoring is associated with lower infant mortality and should be used for all women in labor. However, other experts claim that the practice increases intervention rates and may not prevent neonatal deaths, suggesting a reevaluation of its benefits.
A new NYU report reveals that the phase-out of Teflon-like coatings, which contain PFOA, has led to a significant decrease in low-birth weight babies and related brain damage. The study estimates that this shift has saved over $13 billion in healthcare costs and improved educational prospects for thousands of children.
A study by Johns Hopkins researchers found that specific brain network connections can predict long-term recovery trajectories in patients with severe brain injury after a cardiac arrest. Functional MRI data analysis identified clusters of brain regions that correlate strongly with functional outcomes.
Researchers have discovered that the presence of ApoE4 exacerbates brain damage caused by tau tangles, leading to neurodegeneration and memory loss. Blocking ApoE4 in the brain may prevent these effects, offering a new potential therapeutic target for Alzheimer's disease.
Researchers identified tau, a brain protein, as a potential target for stroke therapies. Mice deficient in tau showed significant protection from excitotoxic brain damage after experimental stroke, offering new avenues for treatment development.
A study from Aarhus University found that 48 hours of cooling can reduce permanent brain damage in cardiac arrest patients, particularly those under 60. The study included 355 patients who were cooled down to 33°C for varying periods and followed up on their recovery.
A new system called NeuroCommTrainer is being developed to help people with unresponsive wakefulness syndrome communicate. The system uses electroencephalography (EEG) measurements to understand brain signals and enable patients to respond with a 'yes' or 'no'.
Researchers have discovered a small protein, Hi1a, that protects the brain from stroke-induced injury. Administered up to eight hours after stroke, Hi1a blocks acid-sensing ion channels and improves neurological performance.
Preliminary study in mice suggests that aged gut bacteria can worsen brain damage after a stroke. Researchers found that mice treated with older gut bacteria had impaired recovery and higher levels of immune cells that worsen stroke severity.
A study by researchers from the Netherlands discovered a clear association between higher levels of N-terminal Pro-B-type natriuretic peptide (NT-proBNP) and brain damage, including smaller gray matter volume and poorer white matter organization. This finding suggests a close link between cardiac dysfunction and subclinical brain damage.
Researchers at the University of Manchester have discovered a potential new drug that reduces brain cell death and promotes neurogenesis after a stroke. The drug, interleukin-1 receptor antagonist (IL-1Ra), is already licensed for use in humans for other conditions and has shown promise in early clinical trials.
Researchers at the Universities of Dundee and Strathclyde have identified a mechanism that allows neurons to protect against spreading brain damage. The discovery, published in Scientific Reports, suggests that stimulating this network activity could limit major brain damage and shorten recovery periods.
Researchers have developed a tailored small molecule that dramatically reduces brain damage after a stroke by inhibiting the production of hydrogen sulfide (H2S) in the brain. The study shows a 70% reduction in stroke severity when tested in rats.
Researchers found that most cases of severe brain damage in newborns occur after birth, despite proper resuscitation. Infections and anemia before birth do not cause the damage, but rather trigger devastating outcomes that can be prevented with timely medical attention.
A study found that chronic exposure to domoic acid causes significant deficits in spatial memory and brain damage in California sea lions. The research documented impaired performance on short- and long-term spatial memory tasks and linked the extent of hippocampal damage to specific behavioral impairments.
Fetal Alcohol Spectrum Disorders (FASD) affect approximately 7,000 UK infants annually, causing irreversible brain damage and long-term health issues. The UK lags behind other developed countries in FASD research, leading to confusion among pregnant women and inadequate support for those affected.
A new imaging technique found damage to nerve tracts connecting different parts of the brain in people with high blood pressure, linked to difficulties in cognitive skills and emotional regulation. DTI provides a way to evaluate pre-symptomatic brain damage in people with high blood pressure.
Research by Dr. Kristian Kragholm found that bystander CPR was associated with a 30% lower risk of nursing home admission and brain damage in survivors of out-of-hospital cardiac arrest. The study included 2,387 adult survivors who did not have pre-existing conditions or live in a nursing home before the cardiac arrest.
Researchers have identified two proteins in blood and cerebrospinal fluid that increase significantly after traumatic brain injury, suggesting they could be used to detect trauma-related brain damage. These biomarkers, UCH-L1 and GFAP, correlate with direct evidence of brain damage and may aid in assessing brain injury following TBI.
A new study published in Neurology found that physically active seniors with small areas of brain damage did not experience a drop-off in movement abilities. In fact, those who were most active showed no decline despite high levels of brain damage, suggesting physical activity creates a 'reserve' to protect motor abilities.
A study published in PNAS found that individuals with prosopagnosia can still recognize human movements, engaging different brain mechanisms. The research team used point-light displays to test patients with brain damage preventing facial recognition, revealing a neural process for comprehending actions independent of the actor.
Scientists have developed an immune-based treatment that reduces brain damage after head injuries by blocking the activation of immune cells. The treatment, called CAP, was tested on mice and found to be effective in reducing brain lesions.
A study by Imperial College London found that xenon gas limits brain damage and improves neurological outcomes in mice, both short-term and long-term. The findings suggest that xenon could be a potential treatment for head injuries in humans.
Damage to the prefrontal lobe is often overlooked but critical for socialization, emotional control and real-life decisions. Studies have shown that distinct areas of the frontal lobes are essential for complex human skills and behavior.
Researchers found that administering EPO immediately after birth significantly reduces brain damage in premature babies. This study builds on previous research showing EPO's neuroprotective effects and holds promise for preventing long-term consequences of preterm birth.
The study reveals that miRNA-9 negatively regulates oligodendrocyte lineage gene 1 during hypoxic-ischemic brain damage. This regulation is crucial for understanding the molecular mechanisms underlying brain damage and myelin repair.
A study published in Neurology found that even mild traumatic brain injury can cause brain damage and disrupt nerve axons in white matter. Cognitive tests showed a 25% decline in verbal letter fluency task scores for patients with injuries, strongly related to imaging measures of white matter damage.
Researchers found that miRNA-9 binds to and potentially reduces the activity of oligodendrocyte lineage gene 1 during hypoxic-ischemic brain injury. This regulatory mechanism may play a role in myelin repair and neurological disorder development.
The study found that 660 nm red light promotes the migration of bone marrow mesenchymal stem cells, enhancing their contribution to treating hypoxic-ischemic brain damage. After phototherapy and cell transplantation, rats showed a significantly increased active avoidance response rate.
Researchers discovered the mechanisms behind long-term depression, a cognitive impairment contributor to Alzheimer's disease. Chronic inflammation and hypoxia activate microglia, weakening neural connections.
Researchers used mass spectrometry to identify 10 differentially expressed proteins in the brain after acute high-altitude hypoxia. These proteins are involved in the electron transport chain and ATP synthase function, providing potential targets for treating hypobaric hypoxia-related brain injury.
Researchers have identified a potential new target for breast cancer treatment: ERBB3, an oncogene that promotes tumor growth. The study also found peritoneal dialysis to be effective in reducing brain damage after stroke by lowering glutamate levels.
The study found that Braintone increased the expression of hypoxia-inducible factor 1α, heme oxygenase-1 and vascular endothelial growth factor in ischemic cortex of rats with middle cerebral artery occlusion. This suggests a neuroprotective effect on ischemia-induced brain damage.
Researchers at SISSA uncover inconsistencies in the dependence of the linguistic system on the motor one, with damage to specific brain regions affecting gesture imitation but not language processing. The study employs voxel-based lesion symptom mapping to establish a link between brain damage and performance decline.