Articles tagged with Brain Damage
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The M-RISE program aims to develop innovative therapies to prevent brain damage caused by cardiac arrest, with a focus on early treatments delivered by bystanders and first responders. The program will explore neuroprotective agents and strategies to improve survival rates and outcomes for patients affected by cardiac arrest.
Experts debate the effectiveness of electroconvulsive therapy (ECT) in treating severe depression, with some arguing it has no long-term benefits compared to placebo and can cause brain damage. Others claim ECT is effective and safe for treatment-resistant depression, with most side effects resolving within weeks.
A new blood test reliably detects signs of brain damage in people with Alzheimer's disease, even before symptoms of confusion and memory loss arise. The test may also identify neurodegeneration in other brain diseases, injuries, and conditions such as multiple sclerosis and traumatic brain injury.
A new 15-minute brain scan predicts damage with 98% accuracy, helping doctors assess the extent of newborn brain damage and plan for long-term development. The scan may also aid in developing new treatments for brain injury in babies.
Researchers have discovered a new and better marker, Neurofilament light (NFL), to assess the degree of brain damage after cardiac arrest. This biomarker shows promise in identifying patients with severe brain damage and could lead to more efficient healthcare decisions.
A new study from the University of Pittsburgh has identified arterial stiffness as a key risk factor for dementia in older adults. The researchers found that individuals with high arterial stiffness readings were 60% more likely to develop dementia over a 15-year period.
A new study published in Clinical Neurophysiology found that attention plays a key role in restoring vision in patients with hemianopia, a condition where half of the visual field is impaired. After five weeks of vision rehabilitation training, patients showed significant improvements in their visual function.
The Swiss Atrial Fibrillation Cohort Study found that 41% of atrial fibrillation patients had previously unknown brain damage, including cerebral infarcts, microbleeds, and lacunes. This brain damage may explain the association between dementia and atrial fibrillation in patients without prior stroke.
A clinical trial found that adrenaline increases the survival rate of patients with cardiac arrests by less than 1%, but almost doubles the risk of severe brain damage for survivors. The study raises questions about the future use of adrenaline in such cases and its impact on patient outcomes.
Researchers studied woodpecker brains for tau protein accumulation, a sign of brain damage in humans. The study suggests that the accumulation might be a protective adaptation rather than indicative of injury, which could have implications for human neurodegenerative diseases.
Dr. Olga Boukrina's research aims to identify high-risk patients with brain damage and type of reading difficulties after stroke, enabling early intervention. Her goal is to develop criteria for effective interventions to help stroke survivors regain their reading ability.
Fetal monitoring specialists argue that continuous electronic monitoring is associated with lower infant mortality and should be used for all women in labor. However, other experts claim that the practice increases intervention rates and may not prevent neonatal deaths, suggesting a reevaluation of its benefits.
A new NYU report reveals that the phase-out of Teflon-like coatings, which contain PFOA, has led to a significant decrease in low-birth weight babies and related brain damage. The study estimates that this shift has saved over $13 billion in healthcare costs and improved educational prospects for thousands of children.
A study by Johns Hopkins researchers found that specific brain network connections can predict long-term recovery trajectories in patients with severe brain injury after a cardiac arrest. Functional MRI data analysis identified clusters of brain regions that correlate strongly with functional outcomes.
Researchers have discovered that the presence of ApoE4 exacerbates brain damage caused by tau tangles, leading to neurodegeneration and memory loss. Blocking ApoE4 in the brain may prevent these effects, offering a new potential therapeutic target for Alzheimer's disease.
Researchers identified tau, a brain protein, as a potential target for stroke therapies. Mice deficient in tau showed significant protection from excitotoxic brain damage after experimental stroke, offering new avenues for treatment development.
A study from Aarhus University found that 48 hours of cooling can reduce permanent brain damage in cardiac arrest patients, particularly those under 60. The study included 355 patients who were cooled down to 33°C for varying periods and followed up on their recovery.
A new system called NeuroCommTrainer is being developed to help people with unresponsive wakefulness syndrome communicate. The system uses electroencephalography (EEG) measurements to understand brain signals and enable patients to respond with a 'yes' or 'no'.
Researchers have discovered a small protein, Hi1a, that protects the brain from stroke-induced injury. Administered up to eight hours after stroke, Hi1a blocks acid-sensing ion channels and improves neurological performance.
Preliminary study in mice suggests that aged gut bacteria can worsen brain damage after a stroke. Researchers found that mice treated with older gut bacteria had impaired recovery and higher levels of immune cells that worsen stroke severity.
A study by researchers from the Netherlands discovered a clear association between higher levels of N-terminal Pro-B-type natriuretic peptide (NT-proBNP) and brain damage, including smaller gray matter volume and poorer white matter organization. This finding suggests a close link between cardiac dysfunction and subclinical brain damage.
Researchers at the University of Manchester have discovered a potential new drug that reduces brain cell death and promotes neurogenesis after a stroke. The drug, interleukin-1 receptor antagonist (IL-1Ra), is already licensed for use in humans for other conditions and has shown promise in early clinical trials.
Researchers at the Universities of Dundee and Strathclyde have identified a mechanism that allows neurons to protect against spreading brain damage. The discovery, published in Scientific Reports, suggests that stimulating this network activity could limit major brain damage and shorten recovery periods.
Researchers have developed a tailored small molecule that dramatically reduces brain damage after a stroke by inhibiting the production of hydrogen sulfide (H2S) in the brain. The study shows a 70% reduction in stroke severity when tested in rats.
Researchers found that most cases of severe brain damage in newborns occur after birth, despite proper resuscitation. Infections and anemia before birth do not cause the damage, but rather trigger devastating outcomes that can be prevented with timely medical attention.
A study found that chronic exposure to domoic acid causes significant deficits in spatial memory and brain damage in California sea lions. The research documented impaired performance on short- and long-term spatial memory tasks and linked the extent of hippocampal damage to specific behavioral impairments.
Fetal Alcohol Spectrum Disorders (FASD) affect approximately 7,000 UK infants annually, causing irreversible brain damage and long-term health issues. The UK lags behind other developed countries in FASD research, leading to confusion among pregnant women and inadequate support for those affected.
A new imaging technique found damage to nerve tracts connecting different parts of the brain in people with high blood pressure, linked to difficulties in cognitive skills and emotional regulation. DTI provides a way to evaluate pre-symptomatic brain damage in people with high blood pressure.
Research by Dr. Kristian Kragholm found that bystander CPR was associated with a 30% lower risk of nursing home admission and brain damage in survivors of out-of-hospital cardiac arrest. The study included 2,387 adult survivors who did not have pre-existing conditions or live in a nursing home before the cardiac arrest.
Researchers have identified two proteins in blood and cerebrospinal fluid that increase significantly after traumatic brain injury, suggesting they could be used to detect trauma-related brain damage. These biomarkers, UCH-L1 and GFAP, correlate with direct evidence of brain damage and may aid in assessing brain injury following TBI.
A new study published in Neurology found that physically active seniors with small areas of brain damage did not experience a drop-off in movement abilities. In fact, those who were most active showed no decline despite high levels of brain damage, suggesting physical activity creates a 'reserve' to protect motor abilities.
A study published in PNAS found that individuals with prosopagnosia can still recognize human movements, engaging different brain mechanisms. The research team used point-light displays to test patients with brain damage preventing facial recognition, revealing a neural process for comprehending actions independent of the actor.
Scientists have developed an immune-based treatment that reduces brain damage after head injuries by blocking the activation of immune cells. The treatment, called CAP, was tested on mice and found to be effective in reducing brain lesions.
A study by Imperial College London found that xenon gas limits brain damage and improves neurological outcomes in mice, both short-term and long-term. The findings suggest that xenon could be a potential treatment for head injuries in humans.
Damage to the prefrontal lobe is often overlooked but critical for socialization, emotional control and real-life decisions. Studies have shown that distinct areas of the frontal lobes are essential for complex human skills and behavior.
Researchers found that administering EPO immediately after birth significantly reduces brain damage in premature babies. This study builds on previous research showing EPO's neuroprotective effects and holds promise for preventing long-term consequences of preterm birth.
The study reveals that miRNA-9 negatively regulates oligodendrocyte lineage gene 1 during hypoxic-ischemic brain damage. This regulation is crucial for understanding the molecular mechanisms underlying brain damage and myelin repair.
A study published in Neurology found that even mild traumatic brain injury can cause brain damage and disrupt nerve axons in white matter. Cognitive tests showed a 25% decline in verbal letter fluency task scores for patients with injuries, strongly related to imaging measures of white matter damage.
Researchers found that miRNA-9 binds to and potentially reduces the activity of oligodendrocyte lineage gene 1 during hypoxic-ischemic brain injury. This regulatory mechanism may play a role in myelin repair and neurological disorder development.
The study found that 660 nm red light promotes the migration of bone marrow mesenchymal stem cells, enhancing their contribution to treating hypoxic-ischemic brain damage. After phototherapy and cell transplantation, rats showed a significantly increased active avoidance response rate.
Researchers discovered the mechanisms behind long-term depression, a cognitive impairment contributor to Alzheimer's disease. Chronic inflammation and hypoxia activate microglia, weakening neural connections.
Researchers used mass spectrometry to identify 10 differentially expressed proteins in the brain after acute high-altitude hypoxia. These proteins are involved in the electron transport chain and ATP synthase function, providing potential targets for treating hypobaric hypoxia-related brain injury.
Researchers have identified a potential new target for breast cancer treatment: ERBB3, an oncogene that promotes tumor growth. The study also found peritoneal dialysis to be effective in reducing brain damage after stroke by lowering glutamate levels.
The study found that Braintone increased the expression of hypoxia-inducible factor 1α, heme oxygenase-1 and vascular endothelial growth factor in ischemic cortex of rats with middle cerebral artery occlusion. This suggests a neuroprotective effect on ischemia-induced brain damage.
Researchers at SISSA uncover inconsistencies in the dependence of the linguistic system on the motor one, with damage to specific brain regions affecting gesture imitation but not language processing. The study employs voxel-based lesion symptom mapping to establish a link between brain damage and performance decline.
A 2.5-year-old boy with severe brain damage was treated with autologous cord blood and showed significant improvement in symptoms, including learning to speak simple sentences and move. The treatment's effectiveness has sparked hope for alternative therapies for infantile cerebral palsy.
A study by OK International and CREPD found high levels of lead in household paints sold in Cameroon, exceeding 50% by weight. The US company PPG is the manufacturer, despite lead being banned in the US for over 30 years.
Researchers at Northwestern University have made significant breakthroughs in understanding the effects of brain damage on language processing and recovery. Studies have shown that with targeted training, patients can regain speech abilities years after a stroke.
A Mayo Clinic study found that blood's tendency to clot may contribute to areas of brain damage called white matter hyperintensities, which can lead to memory problems and increased stroke risk. Women with higher levels of thrombogenic microvesicles were more likely to develop these changes.
A study using rodents found that binge-like drinking can cause damage to the hippocampus after 24 hours, indicated by increased expression of vimentin brain protein. Chronic drinking is known to have detrimental health effects, and this research provides new insights into the threshold for alcohol-induced brain damage.
A new study by UCLA researchers found that women with obstructive sleep apnea have more severe brain damage than men with the disorder. The study also revealed that women are more affected by sleep apnea and experience higher levels of depression and anxiety symptoms.
A study suggests that linagliptin, a commercialized diabetes drug, can stimulate neuroprotection and largely reduce brain damage following stroke. This could lead to better prognosis for type 2 diabetic patients after a stroke.
A Concordia University study has found that adults with mild cognitive impairment (MCI) are impaired in several aspects of executive functioning, particularly inhibitory control. The researchers hope their work will lead to the development of more reliable tools for detecting Alzheimer's disease at an earlier stage.
Researchers have developed a new experimental drug that reduces brain damage and improves motor skills in stroke-afflicted rodents. The drug, 3K3A-APC, extends the therapeutic window of tPA, allowing for more effective treatment beyond the three-hour time frame.
Researchers have designed a new chemical compound that binds 1,000 times more effectively to the target protein in the brain than current drugs, reducing cell death by 40% in animal models. The compound also improves motor function and passes through the blood-brain barrier.
Research reveals that drinking alcohol induces significant brain atrophy and specific shrinkage in cerebral cortex and thalamus in genetically vulnerable mice. The findings support the protective role of dopamine D2 receptors against alcohol-induced brain damage.
Researchers report successful early transplantation of human placenta-derived mesenchymal stem cells into neonatal rats with birth-related brain damage, detecting neurologic improvement.
Repeated head trauma in hockey players causes irreversible brain damage and a condition called CTE. Experts urge a ban on intentional head trauma and severe deterrent penalties to protect player health.
New research reveals that Toll-like receptors play a major role in brain damage risk for newborns, contributing to conditions like cerebral palsy and epilepsy. The discovery could lead to more effective treatment strategies, such as blocking special TLRs to reduce brain damage following hypoxia.
A Mayo Clinic study provides guidance for treating sudden cardiac arrest patients with therapeutic cooling, which slows metabolism and preserves cell health. The study found that both patient groups awoke within three days, supporting the use of hypothermia when indicated.