Articles tagged with Burn Wounds
A recent study published in JAMA found that high-dose intravenous vitamin C did not reduce mortality and persistent organ dysfunction in patients with severe burn injury. Instead, the treatment may be harmful, suggesting alternative approaches for managing burn-related complications.
Researchers developed a topical gel formulation with 4-aminopyridine to treat burn wounds, achieving near-complete closure in 21 days. The gel delivers the drug directly to the wound site, avoiding systemic risks associated with prolonged use.
The US is not prepared for a mass disaster with multiple burn casualties, experts say. Gaps in everyday burn care for children must be addressed before it will be considered ready.
Researchers found that metformin reduced neuroinflammation, suppressed neuronal pyroptosis, and improved mitochondrial function after traumatic brain injury. The study highlights Mfn1 as a crucial molecular link between mitochondrial homeostasis and NLRP3 inflammasome.
Researchers analyzed Oregon Medicaid case data and found that severe burns requiring hospital-level care are a growing threat in the overdose epidemic. People who smoke drugs like fentanyl and methamphetamine account for most of these cases, with butane torches posing a significant risk due to locking mechanisms.
A new study published in BioEssays suggests that humans' increased exposure to high temperature burn injuries may have driven notable genetic adaptations, including faster inflammation and wound closure. These traits helped humans survive small to moderate burns but became harmful for large burns.
Researchers seek to improve burn trauma care by targeting a signaling kinase enzyme with a new-generation inhibitor. The goal is to reduce opioids needed for pain relief and scarring, improving patient recovery from trauma injury.
Researchers have created 'skin in a syringe' by mixing cells with gelatine beads, allowing for 3D printing of functional dermis. This technology could lead to new ways to heal burns and severe wounds with minimal scarring.
A new bacterial cellulose-based hemostatic dressing enables rapid and sustained bleeding control, accelerating wound healing through a triple synergistic mechanism. The material demonstrates excellent biocompatibility and overall safety in comprehensive biosafety evaluations.
A study published in Nature Communications identifies fibromodulin as a protein that forms a complex with interleukin 1β to stop myofibroblasts from forming excessive scar tissue. This finding could lead to a new way to reduce or prevent excessive scarring, benefiting patients recovering from surgery, injuries, or burns.
Researchers at Rensselaer Polytechnic Institute have successfully created hair follicles in human skin tissue using 3D-bioprinting techniques. This innovation has potential applications in regenerative medicine, drug testing, and understanding the complex interactions between skin and topical products.
Researchers from Osaka University identified ten blood proteins associated with mortality in severe burns, including HBA1, TTR, and SERPINF2. These proteins may serve as targets for developing new treatment methods for burns, offering a promising direction for future research.
Researchers found that vaping in the presence of supplemental oxygen can ignite oxygen, leading to burns, fires, or explosions. The risk is particularly concerning for patients with end-stage COPD on oxygen who want to quit smoking by switching to vaping.
Researchers used a biomimetic model to study wound healing in burn and laceration wounds. Fibroblasts were found to clear away damaged tissue before depositing new material, but this process was slower in burn wounds due to more tissue damage. Therapies that promote wound clearance could accelerate healing.
LSU Health New Orleans has been awarded $4.6 million to develop a Burn Prehospital Provider Program, which will provide education and training for military and civilian healthcare providers in different environments. The program aims to improve burn injury care before patients reach a hospital.
A new, dissolvable hydrogel developed by Mass General Hospital promotes wound healing for second-degree burns while minimizing pain and trauma. The biomaterial is highly absorbent, based on green chemistry approaches, and can be dissolved in under five minutes.
A survey study of US youth aged 14-24 found that they understand the short-term risks of sun damage, yet experience high numbers of self-reported burns. Despite using sunscreen, nearly all participants reported skin injuries.
A University at Buffalo-led study found that photobiomodulation therapy sped up recovery from burns and reduced inflammation in mice by activating endogenous TGF‐beta 1, a protein controlling cell growth and division. The findings may improve therapeutic treatments for burn injuries worldwide.
Computer simulations show microbeads can significantly reduce or eliminate bacterial infections in burn wounds when combined with debridement. The tiny plastic spheres compete with bacteria for binding sites, physically keeping them from attaching to host cells.