A new study found that shingles vaccination is associated with lower inflammation, slower epigenetic aging, and overall slower biological aging in older adults. Vaccination showed benefits even four years after the initial dose.
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Public Health Alerts provide concise, data-driven information on disease outbreaks and urgent health events. The new series, launched by NEJM Evidence and CIDRAP, offers expert-reviewed reports to support public health evidence-based care.
Researchers discovered a new evasion strategy used by the varicella zoster virus to affect tissues far from the original site of infection. The virus uses small extracellular vesicles (sEVs) to package and shuttle a protein called IE62, which can travel to distant cells and shut down their antiviral response.
A new study published in JAMA Network Open found live vaccinations safe and effective for children who have received liver or kidney transplants, offering protection against life-threatening conditions. The study showed high antibody levels and minimal adverse events following vaccination.
A recent study by Finnish Institute for Health and Welfare reveals that the two-dose varicella vaccination programme significantly reduced health centre appointments related to chickenpox among children under 12. The number of cases decreased by more than 95% in 2022 compared to pre-vaccination levels.
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A study analyzed Google Trends data to assess the impact of immunization and the COVID-19 pandemic on varicella cases in Europe. The research found a significant decrease in chickenpox cases across the region, suggesting suppressed transmission during the pandemic.
A modelling study in Denmark found that universal varicella vaccination significantly reduces chickenpox-related cases and deaths in both children and adults. The study also showed cost-effectiveness of the vaccine, informing policymakers about routine immunization.
Scientists at Tufts University found that varicella zoster virus (VZV) may activate herpes simplex virus (HSV-1), leading to inflammation and accumulation of Alzheimer's associated proteins in the brain. This suggests a new pathway to Alzheimer's disease.
A study found that chickenpox in childhood results in £24 million in lost income and productivity every year in the UK. Working women are significantly more likely to provide care for sick children, missing an average of 5 days per child. The true cost is likely higher due to underreported cases.
A study by University of California - San Francisco researchers found that over a three-year period, more than a dozen ICE detention centers experienced large, repeated outbreaks of vaccine-preventable illnesses, including influenza, chickenpox, and mumps. The Centers reported nearly half of the infections occurred in two facilities.
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A new study found that the Zoster Vaccine Live shingles vaccination may prevent some older adults from having a stroke, reducing the risk by about 16% for ischemic stroke and 12% for hemorrhagic stroke. The vaccine's protection was strongest among people ages 66 to 79 years.
A study found that adult exposure to chickenpox is associated with a lower risk of developing shingles, but the protective effect does not last forever. The researchers suggest that previous assumptions about childhood varicella vaccination policy in the UK may need to be revisited.
Research reports cases of shingles developing at original vaccination site after chicken pox immunization, highlighting the importance of recognizing vaccine-associated shingles. The condition is rare but may correlate to the vaccination site.
A rare genetic mutation in the POL III sensor can turn chickenpox into a life-threatening infection, leading to brain inflammation and pneumonia. Individuals with this mutation have an increased risk of developing severe illness.
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Emergency room visits for shingles increased among patients aged 20-59 years old after vaccination, while decreases were seen in younger and older groups. Shingles-related costs rose by 111% from 2006 to 2013, with the majority attributed to middle-aged patients.
A University of Michigan-led study analyzing Google Trends data found a significant reduction in chickenpox searches following vaccination implementation in countries like Germany. The study demonstrates the effectiveness of immunization in reducing seasonal outbreaks and offers a novel way to track global childhood disease burdens.
A recent US study found that adults 50 and older are at a 50% increased risk for stroke for 90 days following a shingles episode. The study also revealed that people with shingles had more risk factors for stroke than those without, suggesting worse overall health.
A new study published in the Journal of the Pediatric Infectious Diseases Society finds that US chickenpox cases have declined by 93% since the introduction of the vaccine in 1995, thanks to increased vaccination coverage. This decline is attributed to herd immunity, which protects those who are not immunized themselves.
Researchers at Bar-Ilan University develop novel experimental model that successfully mimics the re-activation of the varicella-zoster virus, which causes chickenpox and shingles. The model allows scientists to test drugs and develop therapies to prevent shingles and potentially impact other viruses targeting the human nervous system.
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A new study finds that shingles significantly increases the risk of stroke in the first six months after symptoms appear. However, patients treated with oral antiviral medication for their shingles may experience lower stroke risks compared to those not treated.
A 14-year study found the varicella vaccine to be approximately 90% effective in preventing chicken pox, with a significant decrease in breakthrough cases over time. The second dose of varicella vaccine was found to be unnecessary for prevention of moderate to severe disease.
A national study of chicken pox admissions found a 68% drop in hospitalizations since the introduction of the vaccine in 2006. The results show that unvaccinated children were more likely to require intensive care treatment, highlighting the importance of herd immunity.
A Kaiser Permanente study found that receiving the herpes zoster vaccine reduced the risk of shingles by 55% in adults 60 years and older. The vaccine also showed effectiveness in preventing shingles in adults over 75, supporting CDC recommendations to offer it to all eligible patients.
A new study confirms that two doses of the varicella, or chickenpox, vaccine provide excellent protection in children against this highly contagious and, in some cases, severe disease. The study found that the effectiveness of two doses of vaccine was 98.3 percent in protecting against varicella, significantly higher than one dose.
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A study published in Journal of Infectious Diseases found that children who received two doses of the varicella vaccine had a 95% lower risk of developing chicken pox. The effectiveness of two doses was 98.3%, significantly higher than one dose at 86%.
A Kaiser Permanente study found the MMRV vaccine doubles the risk of febrile seizures in 1- to 2-year-old children compared to separate MMR and varicella vaccines. The study analyzed 459,000 children and recommended that families without a preference for MMRV receive separate vaccinations.
A study found that refusing the varicella vaccine is associated with a nine-fold increased risk of developing the disease in children. This finding suggests that declining vaccination rates could lead to an increase in the incidence of chickenpox and related complications.
A Kaiser Permanente study found that the chicken pox vaccine significantly reduces the risk of shingles among children. The study followed over 170,000 vaccinated children for an average of two and a half years, resulting in only 122 cases of herpes zoster.
Researchers at UT Medical School in Houston found that knowing a blood relative with shingles doubles one's risk of getting the condition. The study recommends vaccination for individuals with family history to prevent shingles outbreaks.
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New research from the Mayo Clinic suggests that shingles and its complications may have a greater impact on healthy adults than previously thought. The study found that shingles affects at least 1 in every 278 adults each year, with post-herpetic neuralgia being the most common complication, especially among older adults.
Research published in Archives of Disease in Childhood found that severe chickenpox complications occur in hospitalized UK and Ireland children. Vaccination is key to preventing deaths and severe disease.
A study published in Pediatrics confirms the effectiveness of MMR and chicken pox vaccines in extremely preterm infants, contradicting previous concerns about their immune systems. The study found that both term and preterm infants reached a level of immunity considered protective against these diseases.
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A team of NIAID scientists identified a human protein that helps varicella-zoster virus spread from cell to cell. Interfering with this interaction inhibits the virus' spread, and blocking it may lead to new therapies for shingles.
Children undergoing steroid treatment for childhood leukemia are at increased risk of contracting a more severe form of chicken pox, which may result in death. The study found that 54 out of 110 patients with chicken pox experienced severe disease, including two deaths.
Since the introduction of the varicella vaccine, hospitalizations due to chicken pox have decreased by 88% and ambulatory visits by 59%, according to a recent study. These declines are observed across all age groups, with infants under 1 year experiencing the most significant reductions in hospitalizations.
A stronger version of the chickenpox vaccine has been shown to prevent shingles in older adults, reducing incidence by 51% and total burden of pain by 61%. The vaccine also significantly reduces postherpetic neuralgia, a debilitating form of chronic nerve pain.
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The varicella vaccine has significantly reduced the number of chickenpox cases and deaths from varicella, with a 66% decline in mortality. However, its impact on herpes zoster incidence, age distribution, and severity remains uncertain, emphasizing the need for continued vaccination programs.
The chicken pox vaccine has resulted in a 74% decrease in national hospital discharges for the disease, saving $100 million annually. Herd immunity also protects unvaccinated individuals, leading to lower hospital costs among teens and adults.
A study found that vaccinated cases were half as contagious as unvaccinated cases, with varying levels of contagiousness depending on the number of lesions. The authors suggest continued monitoring to improve vaccine policy decisions for future generations.
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The study found that the chickenpox vaccine's effectiveness decreases significantly after one year, with 97% efficacy in the first year and 84% in subsequent years. The vaccine's effectiveness was lower for children under 15 months old, with a 73% efficacy rate.
A review article by Daniel B. Di Giulio and Paul B. Eckburg reports the first confirmed cases of monkeypox in the US, likely introduced through the pet trade and rodent importation. The disease has been mild in the US, with no fatalities, but poses a risk of endemicity in US rodent populations.
A new study has found that chicken pox vaccine is safe and effective for children with chronic kidney disease. The study shows that vaccination can prevent severe complications such as pneumonia and brain inflammation in these patients.
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Researchers are conducting a national study to determine if a vaccine similar to the one given to children to prevent chicken pox will prevent shingles in older adults. The study hopes to enroll 37,000 people over 60 with no prior shingles diagnosis, aiming to boost their immunity and prevent the shingles virus from returning.