Articles tagged with Inflammatory Bowel Diseases
Dr. Daniel K. Podolsky, UT Southwestern president, has been elected to the Institute of Medicine for his scientific and medical achievements. He joins 19 current UT Southwestern faculty members as a national member.
Dr. Daniel K. Podolsky receives the 2009 Julius Friedenwald Medal for his lifelong contributions to gastroenterology and groundbreaking scientific achievements. He credits his colleagues and mentors for his success, highlighting UT Southwestern's role in his career.
Dr. Casey Weaver receives the HudsonAlpha Prize for his groundbreaking work on T cell studies and immune disease. His research has identified a new class of T cells, called Th17 cells, linked to autoimmune diseases such as rheumatoid arthritis and multiple sclerosis.
Researchers have developed biodegradable polymers called polyketals that can deliver drugs, proteins, and snippets of ribonucleic acid to specific areas in the body. The microparticles degrade quickly into biocompatible compounds, reducing inflammation.
Research suggests tricyclic antidepressant desmethylimipramine can restore vagal function and reduce intestinal inflammation in individuals with inflammatory bowel disease and depression. Decreased vagal signaling and increased macrophage presence in the intestine are key factors in increasing susceptibility to intestinal inflammation.
T cells activated during IBD found in PSC livers, re-routed by aberrant attractant protein. Long-lived memory cells may explain delayed liver disease onset after IBD resolution.
A study by Ohio State University researchers found that children with mild inflammatory bowel disease (IBD) are more likely to experience behavioral and emotional problems, including being withdrawn or anxious. The study also showed a link between the severity of IBD and social functioning.
Researchers have discovered a key molecule involved in regulating the immune system that may contribute to stomach cancer. Mutations to this molecule, gp130, induced cellular changes reminiscent of early gastric cancer in mice, highlighting a potential new target for treatment.