Articles tagged with Lung Cancer
A study found that PET scans are more accurate than traditional diagnostic techniques in determining how far lung cancer has spread. PET scans revealed cancer in 27 patients that had spread farther than thought, sparing them from futile attempts at aggressive therapy.
A study at Northwestern University aims to assess whether an experimental drug can reduce carcinogens produced by cigarette smoke, potentially preventing lung cancer. Participants must be heavy smokers with a history of failed quit attempts and no medical problems.
A study of 18,244 Chinese males found that consuming cruciferous vegetables like broccoli was protective against lung cancer. The benefit depends on genetic factors, with subjects lacking the metabolism enzyme GSTM1 showing a 64% decrease in risk of lung cancer.
A recent UI study found that long-term exposure to radon in the home is associated with an increased risk of lung cancer. The study, which included 1,027 Iowa women, found that close to 60% of homes exceeded the EPA's action level for radon, leading to a significant increase in lung cancer risk.
Researchers found that concurrent chemotherapy and daily chest radiation can help lung cancer patients live longer, with an average survival of 17 months. In contrast, sequential treatment resulted in an average survival of 14.6 months.
A chemoprevention regimen containing myoinositol and dexamethasone has been shown to effectively prevent lung tumors in male mice exposed to cigarette smoke. The regimen worked when given daily during exposure or after the mice had returned to clean air, reducing tumor incidence by nearly 40%.
The American Thoracic Society announces new research findings highlighting significant differences in lung function test results between Asian Americans and European Americans. Additionally, experts discuss the potential of gene therapy for treating lung cancer, while studying lung changes caused by smoking and aging.
The UK Markey Cancer Center will establish local coalitions and develop community outreach programs to address cancer barriers in Appalachian regions. The network aims to increase public awareness of clinical trials and promote participation among rural, medically underserved patients.
Researchers found greater numbers of estrogen receptors on lung cancer cells, suggesting a role for this hormone in enhancing tumor growth. Estrogen was shown to increase cell division and tumor growth in both cultured lung cancer cells and animal models.
Scientists at Johns Hopkins have developed a novel approach for detecting cancer based on genetic mutations in mitochondrial DNA. The new test uses bodily fluids such as urine, saliva, and sputum to identify cancer-specific mutations.
Researchers found that office staff, drivers, and unloaders were exposed to similar levels of diesel exhaust due to poor ventilation. This challenges traditional risk assessments based on occupational groups, emphasizing the need for individual testing.
Researchers at Thomas Jefferson University have used gene therapy to replace a damaged Rb2 gene with a healthy version, dramatically shrinking lung cancer tumors in mice. The study provides direct evidence that Rb2 is a tumor suppressor and demonstrates its potential as a target for human gene therapy trials.
A University of Pittsburgh-led research team discovered that the gene for gastrin-releasing peptide receptor is more active in women than men, leading to increased cell proliferation and lung cancer growth. Nicotine from cigarettes also stimulates this gene expression, explaining why women are at a higher risk of developing lung cancer...
Researchers found that women smokers are three times more likely to have the K-ras mutation and nearly four times more likely to die from lung cancer if they have it. The study suggests a link between estrogen and the initiation of K-ras mutant cells in lung tumors.
The NYU Medical Center is launching a large-scale study to determine the effectiveness of combining CT scans with gene markers in detecting early-stage lung cancer in women. The study aims to identify reliable screening tools for women at high risk of developing this deadly disease.
Lung cancer treatment disparities between blacks and whites are attributed to racial attitudes and biases, affecting surgical resection rates and survival outcomes. UCSF specialists emphasize the importance of addressing these inequities through improved communication, screening tests, and clinical trials.
The 9th annual meeting of the European Respiratory Society will address various topics such as lung cancer, asthma, chronic bronchitis, and sleep apnea. The congress will also feature discussions on artificial ventilation methods, non-invasive ventilation, and respiratory problems faced by mountaineers, deepsea divers, and astronauts.
A recent study analyzed gender differences in precancerous changes in smokers' lung tissue, finding that women develop a distinct pattern of bronchial changes and are more susceptible to tobacco-related carcinogens. This research underscores the importance of considering gender in lung cancer screening methods.
A study by UC San Francisco researchers found that adolescent smokers incur more severe DNA damage than adult smokers, which can increase the risk of lung cancer. The study, published in Journal of the National Cancer Institute, suggests that smoking during adolescence may produce physiologic changes leading to persistent DNA damage.
A team of researchers at Duke University Medical Center has mapped a region of human chromosome 11 and identified a new gene, RRM1, that is believed to be responsible for the aggressive nature of lung cancer. The gene's role in DNA production and repair makes it a potential therapeutic target for improving treatment outcomes.
A comprehensive review article by Stephen S. Hecht summarizes the biochemistry, biology, and carcinogenicity of tobacco-specific nitrosamines, linking them to lung cancer formation. The article highlights the importance of understanding these compounds for developing effective chemoprevention strategies and targeted prevention methods.
A large randomized phase III study confirmed the efficacy of paclitaxel plus carboplatin in treating non-small cell lung cancer. Patients who received paclitaxel/carboplatin experienced a greater response rate and improvement in quality of life compared to cisplatin/etoposide.
Researchers discovered a new tumor suppressor gene, BAP1, which regulates BRCA1 activity and is associated with breast and lung cancer. The study reveals that BAP1 mutations can lead to the development of non-small-cell lung cancers.
Thomas Jefferson researchers discovered that lower levels of the tumor suppressor gene Rb2/p130 correlate with increased risk of returning disease and higher mortality in women with endometrial cancer. The study suggests a potential diagnostic test to guide treatment and improve patient outcomes.
A recent study suggests that a human gene variation affecting lung enzyme production may be associated with reduced susceptibility to lung cancer. The study found that approximately 8% of the population has the 'protective' gene form, which reduces by about 54% the risk of developing lung cancer among smokers.
Researchers found that fragments of chromosome 11 slow tumor growth in mice and cell cultures, suggesting a tumor suppressor gene may be present. The study provides new hope for treating lung cancer patients by identifying a potential target for therapy.
Researchers found a strong correlation between low levels of the Rb-2/p130 protein and aggressive, metastasizing lung cancer. The study's findings may lead to a new lung cancer tumor-grading test to enable early diagnosis and tailor treatments.
Researchers at the University of Pittsburgh Cancer Institute have found a biological switch that drives the growth of lung cells in ex-smokers, leading to an increased risk of lung cancer. The 'switch' is triggered by gastrin-releasing peptide (GRP) receptors, which capture circulating hormones and spur lung cell division.
Researchers found that polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor (MGDF) significantly increased platelet counts in patients with advanced non-small-cell lung cancer after chemotherapy. Platelet counts returned to normal within 14 days, faster than in placebo recipients.