Articles tagged with Cardiology
A study reveals disproportionate burden of cardiovascular-kidney-metabolic syndrome among certain populations, emphasizing the need for targeted interventions. The research highlights the importance of addressing socioeconomic disparities in cardiovascular health.
Studies published in JACC found that anti-obesity drugs such as tirzepatide and semaglutide improved cardiac structure and function, as well as reduced cardiac risk biomarkers with lifestyle interventions. These findings suggest that these treatments may have a transformative impact on cardiovascular health beyond weight loss.
A new oral medication, muvalaplin, has shown promising results in lowering lipoprotein(a) levels, a marker of cardiovascular risk. The study's findings suggest that muvalaplin may be a valuable treatment option for individuals with high lipoprotein(a) levels.
Zerlasiran, a small-interfering RNA targeting hepatic synthesis of apolipoprotein(a), significantly reduced time-averaged lipoprotein(a) concentrations by over 80% during 36 weeks of treatment. This finding has potential implications for the treatment of atherosclerotic cardiovascular disease.
A recent study found that electronic letter reminders highlighting the cardiovascular benefits of influenza vaccines increased vaccination rates among over 2 million adults in Denmark. The strategy showed a greater impact on those who have had a heart attack, improving flu shot rates by potentially being cardioprotective. The research ...
Researchers evaluated coronary heart disease polygenic risk scores to determine their performance and agreement at the population level. They found that while scores performed similarly, they generated highly variable individual-level risk estimates, highlighting the need for refined statistical methods.
Researchers studied heart failure patients in zero gravity to assess the impact on left ventricular filling pressures. They found that external constraint affects cardiac hemodynamics, leading to changes in blood pressure and potential new treatment avenues for heart failure management.
New study suggests that small group differences may reflect important benefits for individual patients with cardiomyopathy. The authors recommend explicitly describing patient-level data to support clinical interpretation of results.
A new study by Mass General Brigham researchers found that excessive sedentary behavior increases the risk of heart failure and cardiovascular death. Even among individuals who meet guideline levels of moderate-to-vigorous physical activity, sitting for extended periods can still pose significant health risks. The study's findings sugg...
A study of 89,530 participants found that more than 10.5 hours of sedentary behavior per day increases the risk of heart failure and cardiovascular death, even among those who meet recommended exercise levels. Replacing excessive sitting time with physical activity can lower heart health risks.
The London Health Sciences Centre was the first and only hospital in Canada to implant a new extravascular implantable cardioverter defibrillator (ICD) during clinical trials. The device has been shown to provide long-term safety, efficacy, and performance, offering better comfort and care for patients.
A new study found that even moderate amounts of exercise can reduce the risk of atrial fibrillation, a common heart condition. The research, led by NYU Langone Health, used data from over 6,000 participants and showed that those with higher physical activity levels had a lower risk of developing the condition.
A study analyzing data from over half a million adults found lower survival rates for out-of-hospital cardiac arrests in predominantly Black and Hispanic communities, with improvements seen since the pandemic waned but not yet reaching pre-pandemic levels
A new study found that beta blockers, commonly used to treat heart attack patients with normal pumping function, may lead to increased depression symptoms. Researchers observed more severe depression symptoms in patients who received beta blockers compared to those who did not.
A survey of older adults with heart conditions found that their sexual health impacts mood and well-being, but most healthcare professionals do not offer this information. Patients favor conversations with healthcare professionals about sexual health, including topics like medication side effects and anxiety before sex.
A new plastic device has been developed to secure the surgical field during robot-assisted heart surgery, allowing surgeons to operate with greater independence. The device, made from a type of plastic used in medical implants and aerospace industry, expands to a certain size and retains its shape.
Dr. Robert Harrington, Weill Cornell Medicine Dean, is honored with the 2024 Chairman's Award for his contributions to cardiovascular science and technological innovation. He has dedicated his career to improving research methods and advancing access to care for those with heart disease.
Light ex-smokers experience a CVD risk reduction similar to never-smokers within years of smoking cessation. Heavy ex-smokers require longer periods, up to 25 years, for their residual CVD risk to align with that of never-smokers.
A new study found that the heart sends signals to the brain to increase sleep after a heart attack, promoting healing and reducing inflammation. This communication between the heart and brain is mediated through the immune system and can lead to improved recovery and reduced risk of further cardiovascular events.
Doctors at Mayo Clinic used a new catheter-based approach to draw out resistant pockets of infection in the heart without surgery. Over 90% of participants had their infection cleared, with lower in-hospital mortality compared to those whose infections remained.
Aging adults face increased risk of life-threatening complications when undergoing elective noncardiac surgeries too soon after a heart attack. Delaying surgery for three to six months following a heart attack can significantly reduce this risk, according to new research published in JAMA Surgery.
A study found that using an orbital atherectomy device to remove calcium from blocked coronary arteries before stenting procedures did not improve patient outcomes. The device was used on patients with moderately severe calcification, rather than extreme cases, and did not show significant benefits.
The PROTECTED trial found no significant impact of cerebral embolic protection on periprocedural stroke risk, but suggests a trend towards greater stroke reduction in US cohorts compared to outside the US
The TAVR UNLOAD study found that transcatheter aortic valve replacement did not significantly affect the primary composite endpoint in patients with systolic heart failure and moderate aortic stenosis. However, TAVR improved quality of life compared to clinical AS surveillance.
Researchers propose a comprehensive biomarker-based approach to assess cardiovascular risk by combining markers of chronic inflammation with cardiac health indicators. This approach reveals the significant impact of aging-related inflammation, or 'inflammaging,' on heart health and opens new avenues for targeted interventions.
A new study from Karolinska Institutet reveals a decline in heart failure mortality in Sweden over the last 20 years. Despite improvements, the prognosis for heart failure patients remains concerning, with 25% of those diagnosed in 2022 dying within a year.
A recent study published in JAMA Network Open found that 84% of adults with congenital heart disease reported good or better health-related quality of life, despite complex CHD. However, participants with complex CHD were less likely to meet physical activity guidelines and reported mood disorders.
A recent study found that early aortic valve intervention had no impact on all-cause death or unplanned hospitalization related to aortic stenosis in asymptomatic severe aortic stenosis and myocardial fibrosis patients. The results suggest further research is needed to confirm these findings.
Results from the DanGer Shock trial show a 12.7% reduction in all-cause mortality with routine use of Impella CP in STEMI and cardiogenic shock patients. The Impella ECP pivotal study will also be presented, demonstrating safety and survival benefits for high-risk PCI patients.
Research suggests standing for long periods does not improve cardiovascular health and may increase circulatory issues. Sitting for over 10 hours a day was found to increase cardiovascular disease risk, highlighting the need for regular movement throughout the day.
The third annual TCT MedTech Innovation Forum will address pressing cardiovascular medicine challenges and unveil disruptive solutions. Visionary leaders from the medtech landscape will convene to explore bold solutions, share pioneering insights, and shape the future of cardiovascular care.
Biomedical engineer Jeff Saucerman has received a $3.1 million NIH grant to study low-density lipoprotein receptor 1 and its impact on heart failure and treatment outcomes after a heart attack.
A recent study by the MunichBREW II team discovered that binge drinking can cause clinically relevant arrhythmias in healthy young adults, especially during the recovery phase. The study found that peak blood alcohol values of up to 2.5 grams per kilogram led to an increasingly rapid pulse and increased risk of cardiac arrhythmias.
A nonselective extracorporeal blood purification device reduced cardiac surgery-associated acute kidney injury in nonemergent patients. The study showed a significant reduction of AKI in the first 7 days after surgery.
The conference will feature comprehensive coverage of various topics in cardiovascular medicine, including can't-miss sessions. ACC Middle East chapter teams will also compete in the ACC FIT Jeopardy competition.
Researchers identify modifiable determinants of cerebral blood flow (CBF) and arterial transit time (ATT) in older adults. A higher BMI was associated with lower CBF and longer ATT, while cardiorespiratory fitness linked to longer ATT in specific brain regions.
A new image processing strategy for cardiac magnetic resonance imaging identifies areas responsible for complex ventricular tachycardias, enabling preoperative planning and reducing procedure times and complications. The systematic approach eliminates operator bias and increases sensitivity for detecting these regions.
Researchers at Karolinska Institutet have identified a new potential risk marker for cardiovascular disease in older women. Low levels of an anti-inflammatory antibody are associated with a higher risk of heart attack and coronary heart disease, independent of other known risk factors.
A new study published in the Journal of the American College of Cardiology found that subclinical atherosclerosis is independently associated with the risk of dying from any cause. The study also showed that monitoring the progression of atherosclerosis can improve the prediction and prevention of death from any cause.
A clinical trial found that mavacamten, a cardiac myosin inhibitor, reduced biomarkers of cardiac wall stress and injury in patients with heart failure. The treatment showed no significant reduction in left ventricular ejection fraction.
The study found that progress in reducing excess mortality among Black individuals was stalled by an increase in mortality from external causes. Cardiovascular diseases, diabetes, and certain cancers still pose significant health risks to the US Black population.
Long-term treatment with the nonsteroidal mineralocorticoid receptor antagonist finerenone is estimated to extend event-free survival by up to 3 years among people with heart failure. The FINEARTS-HF randomized clinical trial found this benefit in patients with mildly reduced or preserved ejection fraction.
Researchers at the University of Arizona Health Sciences are studying the molecular mechanisms of coagulation factor XII as a contributor to heart failure with reduced ejection. The goal is to develop better preventive and treatment options for this irreversible condition, which affects millions of Americans.
Research found that babies conceived through assisted reproductive technology have a 36% higher risk of major heart defects compared to naturally conceived babies. The study also showed that multiple births are associated with an even greater risk of congenital heart defects.
The 2024 guideline provides comprehensive recommendations for assessing cardiovascular disease risk and managing patients taking SGLT2-inhibitors. It also highlights the importance of judicious screening and evidence-based management of cardiovascular conditions before, during, and after noncardiac surgery.
A study published in JACC found that metal exposure is associated with progression of plaque buildup in the arteries, comparable to traditional risk factors like smoking and diabetes. The findings support considering metal exposure as a significant risk factor for atherosclerosis and cardiovascular disease.
The new European Society of Cardiology Guidelines recommend regular screenings for Peripheral Arterial Disease (PAD) to prevent complications. The guidelines also emphasize personalized treatment plans, including lifestyle changes, medication, and efficient blockage treatments.
Researchers identified changes in the UBR4 gene as a key driver of fibromuscular dysplasia, a blood vessel disorder affecting up to five percent of adults. The discovery could lead to therapeutic approaches for the condition, particularly beneficial for women who account for 90% of cases.
The RESILIENCE clinical trial explores the effectiveness of remote ischemic conditioning to prevent cardiotoxicity in lymphoma patients undergoing anthracycline-based chemotherapy. The trial aims to reduce heart failure prevalence and improve quality of life for cancer survivors.
A recent study published in the New England Journal of Medicine demonstrates the benefits of catheter-based mitral valve repair for patients with moderate to severe mitral regurgitation. The procedure showed a significant reduction in recurrent hospitalisations and improved quality of life after 12 months.
A recent study published in JACC: Clinical Electrophysiology found that quitting smoking can significantly lower the risk of atrial fibrillation, with former smokers having around 13% lower risk and current quitters having an 18% lower risk. The benefits of quitting are seen shortly after stopping smoking.
A study examines cardiac rehabilitation (CR) knowledge, attitudes, and practice (KAP) among patients with heart failure and cardiology healthcare providers. Key findings highlight the importance of proper knowledge and attitudes in effective self-management, indicating potential room for improvement.
A study at the European Society of Cardiology Congress found that an AI-enabled digital stethoscope helped doctors identify twice as many cases of pregnancy-related heart failure compared to a control group. The tool was 12 times more likely to flag heart pump weakness, leading to better diagnosis and potentially life-saving treatment.
Very intensive lipid-lowering therapy significantly regresses atheroma volume at the lesion level compared to statin therapy alone. This study found greater enlargement of the minimum lumen area and more frequent transition to stable plaque phenotypes with alirocumab treatment.
A nationwide study in Sweden reveals that short-term exposures to lower air temperature and cold spells are associated with an increased risk of myocardial infarction hospitalization after two-six days. Researchers found that this delay in hospitalizations suggests a delayed onset of cold-related impacts on MI risk.
A randomized, placebo-controlled trial found finerenone improved outcomes in patients with heart failure and mildly reduced or preserved ejection fraction. The drug also showed benefits regardless of the ejection fraction and even in patients on other approved therapies.
Researchers found that supplementing potassium only when levels fell below 3.6 mEq/L was noninferior to the current practice of maintaining higher levels, with no increase in adverse outcomes. Lower thresholds did not worsen clinical outcomes or dysrhythmias.
A novel low-dose 3-in-1 blood pressure pill (GMRx2) significantly reduces blood pressure in patients with uncontrolled hypertension. After six months treatment, the GMRx2 group achieved a 5.8mmHg lower systolic blood pressure compared to standard care.
A blood test that measures three modifiable factors together can better predict cardiovascular risk than any marker used alone. The study found that inflammation is at least as important as cholesterol in predicting cardiovascular events.
Researchers found that digital consultations significantly improved medication adherence among heart failure patients, with 28% receiving optimal medication combinations after 12 weeks. The study also showed no negative impact on patient satisfaction or quality of life.