Articles tagged with Gastroenterology
Research presented at Digestive Disease Week 2006 highlights current trends and advancements in GI cancers, clinical studies, and lifestyle choices. The meeting showcases more than 5,000 abstracts on the latest advances in GI research, medicine, and technology.
A study of patients over 65 showed that AMITIZA significantly increased spontaneous bowel movements, improving symptoms of chronic idiopathic constipation. The medication was well-tolerated, with fewer adverse events compared to placebo, and is approved for use in adults regardless of age or gender.
A recent study found that AMITIZA improved symptoms of irritable bowel syndrome with constipation (IBS-C), including abdominal pain and bloating. The treatment was associated with significant improvements in patients' quality of life.
The AGA Institute presented notable clinical and basic science research highlights during the American Gastroenterological Association's (DDW) annual meeting. These findings include studies on the association between flexible sigmoidoscopy and colorectal cancer, as well as the role of Wnt signaling in gut development and repair.
Regular screening significantly reduces cancer deaths in families with hereditary Lynch syndrome, with a 70% decrease in mortality rates. Additionally, research finds that people with IBD-related CRC have similar prognoses as the general population, while a self-propelling colonoscope shows promise in efficient and safe detection.
COX-2 inhibitors and other NSAIDs can provide pain relief for patients with dormant inflammatory bowel disease without increasing the risk of flare-ups. Studies show that these medications are tolerated well by IBD patients, despite minimal risks, and can be a safe option for pain management.
A study found that genetic differences account for approximately 30% of variability in response to COX-2 inhibitors, such as celecoxib and rofecoxib. This suggests a potential target for developing diagnostic methods to identify patients at increased risk of cardiovascular events.
A study published in Gastroenterology found that nearly 2% of the general population has Barrett's esophagus, a condition linked to increased risk of esophageal cancer. The study highlights the need for screening and awareness among patients and physicians.
A recent study published by the American Gastroenterological Association found that consuming more than two cups of coffee or tea per day can reduce the risk of chronic liver disease by half. Researchers discovered that caffeine played a significant role in this protective effect, suggesting potential applications for liver health.
A nationwide survey found that 54% of NSAID users were unaware of potential side effects, and 18% had previously experienced complications. The study emphasizes the need for patient and physician education to prevent unnecessary complications from painkiller misuse.
A recent study found that even healthy people taking high doses of ibuprofen are at risk of internal bleeding, with blood loss ranging from 40mL to 299mL. The research highlights the need for caution when using ibuprofen, particularly in older adults and those with debilitating conditions.
New studies show that young African Americans are at a much higher risk of developing pre-cancerous polyps compared to other racial groups. The American College of Gastroenterology recommends that African Americans begin colonoscopy screening at age 45, as opposed to the current recommended age of 50.
Researchers found that IBS patients often believe it causes cancer, is caused by food allergies or intolerance, or changes in daily routine. Patients also reported significant concerns and effects on daily life, indicating a need for improved education and support.
Researchers found that both lying and truth-telling affected cardiac symptoms, while the act of lying was associated with gastric symptoms. The EGG showed a significant decrease in normal gastric slow waves when the subject was lying, corresponding to an increase in average heart rate.
Researchers found that people with diabetes are 1.4 times more likely to develop colon cancer compared to those without the condition. The study analyzed data from a nationally representative sample of patients and controlled for various factors, including age and obesity.
A study found that treatment with tegaserod significantly improved work attendance among patients with IBS symptoms of abdominal pain/discomfort, bloating and constipation. The study showed a 27% decrease in self-reported absenteeism and improvements in daily activities for approximately 50% and 40% of patients respectively.
A new study found that second and third-born children perceive greater parental protectiveness than only children, especially in mothers with IBS. This increased protectiveness may lead to more school absences and reported symptoms in later-born children of IBS mothers.
Researchers found that obese individuals who engaged in physical activity experienced fewer gastrointestinal (GI) symptoms compared to those with sedentary lifestyles. High body mass index (BMI) was linked to increased symptoms of irritable bowel syndrome (IBS), abdominal pain, and diarrhea.
The NIH has launched a new commission to address digestive diseases, building on the findings of a previous study that highlights the economic burden of these conditions. The commission will guide research into combating digestive diseases and translate advances into clinical practice.
Research confirms that patients with inflammatory bowel disease (IBD) are more likely to develop conditions such as asthma, multiple sclerosis, and other demyelinating disorders. The studies found a nearly two-fold increased risk of multiple sclerosis in IBD patients, highlighting the need for closer monitoring.
A recent study published by the American Gastroenterological Association found that nearly 80% of Asian patients with chronic HCV developed cirrhosis after 60 years of infection. The study's results confirm that fibrosis progression is the same across ethnic groups, leading to cirrhosis and liver disease at a similar rate in everyone.
Researchers found that older patients with newly diagnosed diabetes are considered a high-risk group for developing pancreatic cancer. The study, conducted by the Mayo Clinic College of Medicine, included 2,122 patients aged 50 and older who were diagnosed with diabetes between 1950 and 1995.
Research estimates a lifetime cancer risk of 0.14% and 0.022% from virtual colonoscopy, with the colon, stomach, and bladder being at greatest risk. While low radiation risks are promising, practical issues such as bowel preparation and patient compliance remain to be addressed.
Researchers found that a diet high in vitamin B6 may reduce the risk of colorectal cancer in women, particularly those who consume alcohol. The study suggests that maintaining a normal or high intake of vitamin B6 can help prevent the development of cancerous polyps in the colon.
Researchers found that rifaximin significantly improved disease activity in patients with Crohn's disease. The analysis of 8 patients showed a mean decrease in Harvey Bradshaw index of 7.1, indicating potential effectiveness as a treatment.
A survey of 1908 participants with gastroesophageal reflux disease (GERD) in Europe and the US found that nearly half experience sleep problems, impacting work and personal lives. The study suggests that GERD symptoms can be related to other health conditions like depression and anxiety.
Studies evaluate wireless capsule endoscopy, barium contrast series, and endoscopic gastric plication for small bowel surveillance and GERD treatment. These procedures show varying degrees of success in detecting polyps and reducing symptoms.
Researchers say virtual colonoscopy may be the answer to improving screening rates for colorectal cancer. The non-invasive test is highly sensitive and specific, while also being convenient and cost-effective, with minimal risk of side effects.
Researchers found that adding a fish oil, soluble fiber, and antioxidant supplement to standard medical therapy significantly reduced the dose of corticosteroids needed to control symptoms. The study provides an alternative treatment option for patients with ulcerative colitis.
Researchers found that overweight patients, those with moderate income, and women survived longer with esophageal and stomach cancer. Premature birth significantly increases the risk of esophageal adenocarcinoma, potentially linked to gastroesophageal reflux disease.
Researchers at U-M Health System found that disease severity in patients with ulcerative colitis can be accurately evaluated without frequent lower endoscopies. The study suggests using non-invasive indices, such as patient-reported symptoms, to monitor disease activity and spare patients the discomfort of regular endoscopies.
The American Gastroenterological Association recommends colonoscopy as the preferred screening method for colorectal cancer due to its ability to detect and remove precancerous polyps. In-office fecal occult blood tests are not recommended as a standalone screening test, but can be used in conjunction with flexible sigmoidoscopy.
A study of 43 patients found that 71% who used NSAIDs for over 90 days had visible injury to their small intestine, ranging from small erosions to severe ulcers. The study highlights the potential risks of long-term NSAID use and calls for further research on the clinical significance of these findings.
CT colonography offers improved accuracy and convenience for colorectal cancer screening, but challenges remain in standardization, patient preparation, and interpretation of results. Standardization and training are necessary for widespread adoption.
A study estimates that 41 million Americans are eligible for colorectal cancer screening, but only a fraction have received it. The capacity for screening tests like flexible sigmoidoscopy and colonoscopy is limited, with colonoscopies being the most expensive option.
A retrospective cohort study of 198 children who underwent fundoplication at Texas Children's Hospital from 1996-1999 found that fundoplication is not a long-term solution for treating GERD in children. Alternative medical treatments, such as histamine-2 receptor antagonists and proton pump inhibitors, are recommended instead.
A new study identifies 38 patients under 50 with colorectal cancer, half with family history. The research concludes that African-Americans and Hispanics should begin screening at age 40 regardless of family history.
A new study on celiac disease over a 52-year span reveals a significant shift in patient demographics and symptom presentation. Fewer patients are diagnosed with diarrhea, while more are discovered through screening, leading to an increase in silent diagnoses.
Increased use of virtual colonoscopy is expected to lead to a decrease in traditional colonoscopies due to improved detection rates. Virtual colonoscopy without bowel preparation has been found to be as effective as traditional colonoscopy in detecting colorectal polyps, increasing patient compliance and potential screening rates.
A study found that cigarette smokers are more likely to have polyps, a greater number of polyps, and larger polyps than non-smokers. Vitamin C supplements were also associated with the absence of polyps in patients who regularly consumed them.
A new trial shows promising results for Cilansetron in treating IBS with diarrhea, improving quality of life and relieving symptoms. The medication has been shown to be well-tolerated and efficacious in both men and women.
A retrospective cohort study of 24,918 patients with type 2 diabetes found those on more than three years of insulin therapy have a significantly higher risk of developing colorectal cancer. The study's lead author hopes the findings will lead to more effective cancer prevention efforts.
The American College of Gastroenterology states that colonoscopy is the best and gold-standard test for colorectal cancer screening and prevention. It prevents about 80 percent of colorectal cancers from developing by removing precancerous polyps, while CT colonography has shown poor results in comparison.
Virtual colonoscopy shows significant promise for colorectal cancer screening, but practical issues must be addressed before widespread use. Issues include standardization of test performance and interpretation of results, as well as the potential need for multiple procedures to detect and remove polyps.
Virtual colonoscopy has shown promise as a colorectal cancer screening option, with limitations in detecting flat polyps and varying results in clinical trials. Further research is needed to determine the optimal size for removing small growths and standardizing test performance.
Eosinophilic esophagitis (EE) is a rapidly rising disorder characterized by severely elevated levels of eosinophils in the esophagus, leading to vomiting and difficulty swallowing. The disease has a familial pattern suggesting genetic or environmental factors, warranting further study.
The American Gastroenterological Association disputes the validity of a recent study suggesting that too many surveillance colonoscopies are being performed. The study, published in Annals of Internal Medicine, highlights the importance of determining the clinical significance of small polyps and notes the need for further research to ...
Researchers found that consumer awareness of NSAID side effects has increased over time, but many patients still take excessive doses, putting themselves at risk for serious complications. The study emphasizes the need for education and discussion with physicians to recognize risk factors and prevent adverse reactions.
Researchers found that among patients with confirmed Crohn's disease, clinical decisions based on capsule endoscopy findings improved outcomes in 95% of patients. Capsule endoscopy was also 100 percent effective in excluding a diagnosis of Crohn's disease.
A large cohort study reveals that diabetes significantly increases the risk of developing chronic liver disease and liver cancer. Regular testing of liver enzymes is recommended for patients with diabetes to monitor for potential toxicity.
A substantial majority of people who purchased Prilosec OTC complied very well with the label instructions. The study found that frequent heartburn sufferers increased consultation with their physicians after using the medication.
A new study on virtual colonoscopy has shown remarkable improvement in diagnosis but also revealed significant discomfort for patients. Gastrointestinal specialists emphasize the need for verification of results and caution against relying solely on virtual colonoscopy.
Patients with achalasia often experience impeded digestion due to reduced muscle contraction and sphincter relaxation. Research finds that nerve cell loss may cause constipation in these patients, which persisted even after treatment for achalasia.
Studies link fructose intolerance to IBS symptoms; patients with diet modifications show improved symptoms. Fat consumption is also linked to gastrointestinal disorders, according to a new study.
A study of nearly 2,000 patients found that heavy alcohol consumption was associated with a higher risk of colorectal cancer. Patients with significant spirits intake may benefit from more intensive screening, according to the American College of Gastroenterology.
A multi-center study found that 63% of patients with mild to moderate ulcerative colitis achieved remission after taking four packets of VSL#3 daily for six weeks. The probiotic composition demonstrated safety and efficacy in patients not responding to conventional therapies.
Researchers found that smoking is an important risk factor for developing colorectal polyps, with smokers being more likely to have larger polyps and a greater potential for malignancy. The study suggests that physicians should consider performing screening colonoscopy in current smokers before age 50.
A study found that treating acid reflux significantly improved quality of life and reduced asthma symptoms in patients with moderate to severe persistent asthma. The use of a proton pump inhibitor, such as lansoprazole, was shown to offer significant benefits for these patients.
A new survey reveals that over 65% of IBS patients in the US experience debilitating symptoms, with 97% consulting healthcare professionals in the past three months. The study also shows significant economic burdens, with $258 average spend on GI disorders per month.
A study published by the American College of Gastroenterology found that wireless capsule endoscopy outperformed traditional push enteroscopy in detecting small intestine lesions causing obscure GI bleeding. The technology identified potential sources of bleeding in 70% of patients, compared to 45% with push enteroscopy.