Articles tagged with Hydrolysis
Researchers have created a novel synthetic enzyme that efficiently converts CO2 into formic acid, opening up new possibilities for biotechnological production of valuable chemicals and fuels. The enzyme, FAR, tolerates high concentrations of formate and is stable in both living cells and cell-free systems.
Researchers found that iron oxyhydroxide nanominerals can catalyze the breakdown of harmful plastic additives. The study shows that mineral structure plays a crucial role in determining degradation rates.
Researchers revealed the molecular mechanism of acarbose degradation by acarbose-preferred glucosidase, identifying key nucleophiles and substrates. The two-step degradation mechanism involves an M1 intermediate, providing targets for designing novel anti-degradation diabetes therapeutics.
Researchers at the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) demonstrate industrial viability of hydrothermal pretreatment for producing second-generation biofuels from oilcane lignocellulose. The study showcases an efficient method for converting oilcane into bioethanol, reducing dependence on foreign oil.
Scientists have uncovered the molecular structure of Mycoplasma mobile's twin motors that power its gliding ability, using cryo-electron microscopy. The complex structure reveals a new mechanism by which energy from ATP hydrolysis is converted into motility.
Kyushu University researchers create a microwave flow reaction device that converts complex polysaccharides into simple monosaccharides, producing glucose. The device utilizes a continuous-flow hydrolysis process, where cellobiose is passed through a sulfonated carbon catalyst heated using microwaves.
Researchers from Leiden University discuss targeting ABC transporters in pancreatic ductal carcinoma (PDAC), a cancer with poor survival rates. The authors highlight the potential of inhibiting ABC transporters to overcome chemoresistance and suggest developing stratification protocols to identify patients most likely to benefit.
Researchers discover that methane sulphonic acid (MSA) hydrolysis can produce higher yields of xylose and activated carbon from hemp seed hulls compared to traditional methods. The use of MSA also leads to the formation of high surface area activated carbon with improved delignification properties.
Brazilian researchers create a nickel phosphide electrode that efficiently produces hydrogen through water molecule breakdown. The material's granular structure enables good interaction with the electrolyte, making it suitable for alkaline, neutral, and acidic conditions.
A new study by University of Toronto researchers found high levels of toxic PFAS chemicals in Canadian fast-food packaging, contaminating the food people eat. The study suggests that PFAS can enter the environment through waste streams and never break down, posing significant health risks.
Scientists studied F1-ATPase function in bacteria to clarify the angle of rotation during ATP hydrolysis. The study revealed three sets of short and long dwells associated with different intervals per revolution, resolving a long-term debate over the ATP-cleavage shaft angle.
A study by Pusan National University researchers investigates the effects of mild acid hydrolysis on sulfated fucans in sea cucumbers and sea urchins. The results show selective 2-desulfation, leading to an 8-sugar-long oligosaccharide production.
Researchers have developed a novel technique to produce hydrogen peroxide without releasing carbon dioxide, reducing greenhouse gas emissions. The method uses photocatalysis and carbon nitride as a catalyst, making it more cost-effective and environmentally friendly.
Researchers have modelled a key mechanism by which DNA replicates, revealing details about how helicases wrangle DNA during replication. The simulations showed each step of translocation can travel more than 12 nucleotides along the backbone, pinpointing interactions involved in long-distance movement.
Researchers at Texas A&M University have developed an organic material that uses less energy to dry air, enhancing the efficiency of heating, ventilation and air conditioning (HVAC) systems. The polyimide-based dehumidifiers can bring down the cost of HVAC systems, which currently cost thousands of dollars.
Researchers developed degradable, cargo-bearing polymers from xylose-based monomers that can be hydrolyzed to release useful molecules. The polymers' linkages determine their degradation rate, producing pyrroles or furans.
Researchers have created a stable and efficient membrane using an in-situ growth idea, addressing the challenges of large-scale production. The new membrane outperforms existing commercial membranes in terms of starting voltage, stability, and hydrolysis ability.
Researchers created 'active droplets' that release drugs at a constant rate over several days, reducing the risk of overdose. The droplets are stable for longer due to hydrolysis protection and can be loaded with varying doses.
Researchers at Shinshu University have discovered acid hydrolysis of vinyl polymer breaking down into salicylic acid and acetic acid, forming the basis for aspirin production. This innovative process has the potential to recycle vinyl on an industrial scale, reducing plastic waste and its environmental impact.
Researchers at the University of Münster have identified a new reaction mechanism for converting biomass into fuels and chemicals using mechanical force. The mechano-catalytic reaction reduces energy requirements and eliminates unnecessary steps, leading to a more efficient and environmentally friendly process.
A new consolidated bio-saccharification (CBS) technique has been developed to improve lignocellulose conversion efficiency and reduce costs. The CBS process integrates enzyme production, cellulose hydrolysis, and fermentation in one step, resulting in a 50% reduction in processing time and increased sugar yield.
The study reveals that ATP binding induces ClpB ring formation and hydrolysis causes significant structural changes between round, spiral, and twisted-half-spiral conformations. The results clarify individual roles of AAA1 and AAA2 domains in the disaggregation reaction.
Researchers at Tohoku University used large-scale hybrid quantum-classical simulations to explain ATP hydrolysis energy. They discovered the microscopic mechanism of AHE release in water, finding that electronic-state stabilization and hydration free energy compensate for each other.
Researchers at UNIST developed a metal-based substance that hydrolyzes amyloid-β proteins, reducing their toxicity. The cobalt-based complex has the potential to penetrate the brain-vascular barrier and directly interact with the protein in the brain.
Scientists found that nickel N-heterocyclic carbene (NHC) complexes decompose into initial reagent and nickel hydroxide when exposed to water. The rate of hydrolysis varies depending on the type of NHC ligand, with some complexes breaking down quickly while others remain stable for over a week.
Researchers found that supercritical carbon dioxide (SC-CO2) pretreatment increased sugar yields from empty fruit bunches by up to 37%, with the addition of alkali further increasing glucose production. The study provides visual evidence of surface changes in pretreated biomass.
A novel approach using a motile bacteria and microbial lug-gage enhances cellulose degradation in solid-state conditions. This method overcomes limitations of current biocatalysts, offering a promising solution for efficient and cost-effective cellulose hydrolysis.
A study reveals enzymatic hydrolysis and drying significantly alter lignocellulosic biomass nanostructure, reducing pore volume by up to 80%. The accessible reaction space is also reduced, hindering hydrolysis. This work sheds light on the importance of physical features in defining hydrolysis rates.
Researchers at the Energy Biosciences Institute developed a mechanistic model of enzymatic hydrolysis of cellulose, improving understanding of enzyme-substrate interaction. The model tracks individual cellulases and key cellulose surface properties, revealing critical factors affecting enzyme activity and sugar production.
A team of UCR researchers has successfully engineered a synthetic cellulosome in yeast, increasing its ethanol-tolerant capabilities. This breakthrough could enable efficient consolidated bioprocessing for bioethanol production from biomass, making renewable fuel production more economical.
A team of researchers found the cellular mechanism that prevents protein mutations and accumulation, a hallmark of Alzheimer's and Parkinson's. This discovery may lead to new insights into neurological disease origins and potential therapeutic strategies.