Articles tagged with Hela Cells
Cryo-optical microscopy captures high-resolution, quantitatively accurate snapshots of dynamic cellular processes at precisely selected timepoints. This technique enables the observation of transient biological events with unprecedented temporal accuracy.
Research reveals a mechanism by which daughter cells safeguard themselves against UV-damaged RNA inherited from mother cells. DHX9 stress granules, a special type of stress granule, trap and neutralize damaged RNA to prevent harm.
Researchers at Ritsumeikan University have created a technique to precisely control the concentration of chemicals in droplets using electrowetting-on-dielectric (EWOD). This allows for accurate drug screening and cell-based analysis, enabling the efficient handling of substances on a smaller scale than traditional pipettes.
Australian researchers have discovered a new mechanism by which T cells can react to lower doses of antigens, leading to a 50-fold increase in T cell activation sensitivity. This finding opens up new possibilities for developing more effective immunotherapies.
Researchers developed a multifunctional microfiber probe for real-time monitoring of cellular molecules and changes in cell morphology. The nanowire probe enabled sensitive detection of refractive index distribution in single living cells during apoptosis.
A team of researchers has created a nanostructured microscope coverslip that allows high-contrast pseudo 3D images of unstained biological cells to be obtained. This breakthrough method enables the visualization of cell shape and nucleus details, crucial for disease detection.
The study investigates the role of cell cycle progression on analyzing telomerase activity in cancer cells based on an AIEgen-based fluorescence detecting system. The results show that cancer cells exhibit increased fluorescence intensity during different stages of the cell cycle, while normal cells do not.
Researchers at Toyohashi University of Technology developed a low-cost method for intracellular delivery using titanium-oxide nanotubes and nanosecond pulse lasers. The study successfully delivered propidium iodide and fluorescent dextran into HeLa cells with high efficiency and cell viability.
Researchers have created an algorithm that significantly reduces the time taken to analyze HeLa cancer cells using Electron Microscopy. The new approach uses deep learning architectures and achieves results in minutes, compared to a week for human experts.
Cancer cells can form large-scale structures in the laboratory, similar to those seen in vivo, allowing researchers to gain insight into the forces behind this phenomenon. The study suggests that understanding these interactions may hold potential for combating cancer.
Researchers developed a new type of micromotor that can move around single cells and microscopic particles in three dimensions without damaging them. The technology has potential applications in targeted drug delivery, nanomedicine, tissue engineering, regenerative medicine and other biomedical fields.
Scientists at ASRC have created a new class of molecules showing potent anti-Zika activity and low toxicity towards animal cells. These compounds may become the basis for a Zika-specific therapeutic, with potential applications in treating other viruses and bacterial infections.
A Russian scientist has received funding to analyze the tumor microenvironment and develop new cancer therapies. The project aims to create targeted treatments with minimal side effects, building on gene and cell technologies.
Russian researchers created star-shaped nanoparticles with sharp spikes using laser irradiation for intracellular delivery. The method achieved efficiency rates of over 95% and minimal toxicity, making it a potential alternative to existing technologies.
Researchers studied HeLa cells and found that cancer cells accumulate harmful mutations, but about 13% of cells remain mutation-free. This allows them to survive despite reducing their growth rate and chromosome numbers. The study suggests that high rates of deleterious mutations are necessary for the population to die out.
Researchers developed novel quantum dots for enhanced mRNA FISH, achieving accurate RNA counting and 3D cell imaging. The new probe overcomes FISH limitations with compact quantum dots, providing stable and efficient labeling.
Researchers describe how Oropouche virus replicates in human cells by hijacking the Golgi complex, a process that could lead to novel targets for preventing infection. The study provides new insights into the replication mechanisms of emerging viruses.
Researchers at the University of Münster developed a new substance similar to cholesterol, allowing visualization in living cells. The study enables imaging of membrane dynamics without damaging the membrane.
Researchers have developed a water-soluble warped nanographene molecule that induces cell death when exposed to blue laser light, showing promise for fluorescent cell imaging and possibly eradication of cancer cells. The molecule exhibits green fluorescence under ultraviolet or blue light and has low cytotoxicity.
Researchers have synthesized a water-soluble warped nanographene that exhibits photodynamic properties, killing human cells upon irradiation. The material's biocompatibility and fluorescence make it suitable for bioimaging and potential therapeutic applications.
Researchers found over 30,000 publications reporting on misidentified HeLa cells, leading to potentially invalid research data and reproduced results. The study aims to raise awareness about the problem and promote caution when interpreting results.
Researchers found that six genes, including four from a peroxiredoxin family, were affected by titanium dioxide nanoparticles in human HeLa cells and monkey kidney cells. The effect was seen after 24-hour exposure, with changes of about 50% in enzyme expression.
A new technology called Sticky-flares offers the first real-time method to track and observe RNA distribution in living cells. The tool helps scientists understand the complexities of RNA better than any analytical technique, with potential applications in disorders such as mental disability, autism, and cancer.
Researchers developed an acoustic-based microfluidic device to separate circulating cancer cells from blood samples with high accuracy. The device uses surface acoustic waves to push CTCs out of the fluid stream, making it a potentially game-changing technology for non-invasive diagnostics and treatment monitoring.
Researchers at Max Planck Institute show that supplying D-lactate or glycolate, two products of the gene DJ-1, can restore mitochondrial activity and prevent neuron degeneration in Parkinson's disease. These substances may also have a general role in protecting cells from decline.
Jay Shendure received the 2014 HudsonAlpha Life Sciences Prize for his pioneering work on next-generation sequencing technologies. He completed a detailed DNA sequence of HeLa cells, the first immortal human cell line grown in a lab.
A team of researchers has created a way to induce normally mild-mannered cells to gobble up their undesirable neighbors by exploiting a molecular signal. This breakthrough could lead to therapies that enlist patients' own cells to better fend off infection and even cancer.
Researchers successfully controlled nanomotors inside live human cells, powered by ultrasonic waves and steered magnetically. The ability to manipulate cells from the inside holds promise for treating diseases such as cancer.
Researchers at Scripps Research Institute develop new drug discovery technique to quickly and cheaply identify antibodies that protect human cells from viral infections. The technique successfully identifies two antibodies that prevent cold virus-induced cell death, highlighting its potential for treating various diseases.
Researchers at the University of Washington published a comprehensive portrait of the genome of HeLa cell line, shedding light on its unique replication properties and stability. The study also highlights the importance of haplotypes in characterizing cancer genomes and epigenomes.
The NIH has reached an agreement with the Lacks family to allow controlled access to the whole genome data of HeLa cells, a valuable reference tool for researchers. The policy respects the family's wishes while enabling scientific progress and includes public acknowledgement of their contribution.
Researchers developed a diagnostic biological 'computer' network in human cells that recognizes cancer cells and triggers their destruction. The network uses a combination of five specific miRNAs to identify HeLa cancer cells and destroy them, while leaving healthy cells intact.
Researchers at Johns Hopkins Medicine have discovered a natural product from traditional Chinese medicine that blocks gene control machinery in cells, suggesting potential as an anticancer drug. The compound, triptolide, has been shown to be effective against cancer and other conditions.
This year's AAAS/Subaru Science Books & Film competition recognizes four authors, an illustrator, and a photographer for their scientifically sound works promoting science literacy. Winners explore topics like climate change, honey bee colonies, and biomedicine.
Scientists at St. Jude Children's Research Hospital have discovered a new drug that can temporarily disable the ATM protein, making tumor cells more susceptible to irradiation and chemotherapy. The treatment, CP466722, has no significant side effects, according to the study published in Cancer Research.