Articles tagged with Type 2 Diabetes
Researchers found that genetic screening for type 2 diabetes is not significantly better than traditional risk factors such as weight, blood pressure, and blood sugar levels. The study identified 18 gene variants associated with increased risk, but the value of genetic screening improved as more risk genes were discovered.
A new study published in JAMA found that low-dose aspirin did not significantly reduce the risk of atherosclerotic events, including coronary and cerebrovascular events, in patients with type 2 diabetes. However, aspirin was effective in reducing fatal coronary and fatal cerebrovascular events.
Using precise microscopes, University of Missouri researchers identified tumor necrosis factor-α and advanced glycation end products as major contributors to blood vessel dysfunction in type 2 diabetes. This discovery could lead to new treatments for blood vessel diseases and disorders in people with type 2 diabetes.
A new review article highlights the potential of sirtuins to treat diseases of aging such as Type 2 Diabetes and mitochondrial disorders. Early clinical studies suggest that SIRT1 activation may lower glucose and improve insulin sensitivity.
The study found that liraglutide improved blood glucose control compared to glimepiride, with significant reductions in HbA1c levels. Participants receiving liraglutide also experienced weight loss and decreases in systolic blood pressure, making it a promising treatment for type 2 diabetes.
JANUVIA showed longer-term efficacy and safety profile in combination therapy with metformin, improving glycemic control in patients with type 2 diabetes. Additionally, the study demonstrated that JANUVIA provided glycemic control regardless of baseline characteristics.
A new study led by Dr. Keiko Watanabe found that periodontitis accelerates insulin resistance in rats with a high-fat diet. The research will explore the impact of periodontitis on diabetic complications in the retina, aorta and pancreas.
A study published in Diabetes Care found that young men with type-2 diabetes have significantly lower levels of testosterone, which can impact fertility, muscle development, and increase the risk of heart disease. The study also highlights the potential clinical implications of low testosterone in these individuals.
The International Diabetes Federation is funding a two-year study to evaluate the effectiveness of motivational interviewing in improving self-management education for adults with uncontrolled type 2 diabetes. The Baylor Healthcare System project aims to increase program completion rates and long-term diabetes control.
A study of 788 US adults found that those with diabetes had higher levels of arsenic in their urine compared to those without diabetes. Inorganic arsenic from contaminated drinking water may play a role in the development of type 2 diabetes.
A study of 788 US adults found that those with higher arsenic levels in their urine were more likely to develop type 2 diabetes. The researchers also discovered that the presence of certain organic arsenic compounds did not increase diabetes risk.
A new USC study found that overweight Hispanic children are at significant risk for pre-diabetes, with persistent pre-diabetes during growth associated with progression towards type 2 diabetes. The study highlights the importance of regular monitoring of these children to detect potential risks early.
A recent study published in Diabetes Care found that losing weight soon after a type 2 diabetes diagnosis can lead to better blood pressure and blood sugar control. The study followed over 2,500 adults with type 2 diabetes for four years and showed that those who lost weight were up to twice as likely to achieve their targets.
A Columbia University study found that periodontal disease can be an independent predictor of incident Type 2 diabetes. Over a 20-year follow-up, individuals with elevated levels of periodontal disease were nearly twice as likely to develop Type 2 diabetes compared to those without periodontal disease.
A recent survey found that 94% of doctors recognize the relationship between obstructive sleep apnea (OSA) and type 2 diabetes, but only 47% conduct routine screening. The International Diabetes Federation calls for increased awareness, research, and clinical practices to address treatment.
A large population-based study of 659,000 women found that almost 20% develop type 2 diabetes within 9 years of pregnancy. The rate of diabetes increased rapidly after delivery, peaking at 9 years. Higher urban statistics and older mothers also increase risk factors for gestational diabetes.
Eating a diet high in sugar-sweetened beverages and low in fruits and vegetables may increase the risk of type 2 diabetes. Consuming more than one soft drink per day or drinking two or more fruit drinks daily increases the risk by 24% and 31%, respectively. In contrast, a low-fat diet does not appear to impact diabetes risk.
A study by Boston University researchers found a significant association between regular consumption of sugar-sweetened soft drinks and fruit drinks with an increased risk for type 2 diabetes in African-American women. The incidence of type 2 diabetes rose with increasing intake of both types of drinks.
A recent study published in Diabetes Care found high levels of oxidative stress in coronary heart disease patients without type 2 diabetes were actually indicative of overt diabetes. This discovery highlights the importance of considering glucose abnormality as a potential underlying condition for heart disease.
A study found that higher levels of liver protein fetuin-A are associated with an increased risk of developing type 2 diabetes in older adults. The researchers measured fetuin-A levels in 519 diabetes-free individuals aged 70-79 years and found a significant association between fetuin-A and the development of diabetes.
A long-term study shows that resveratrol improves bone health, reduces cataracts and cardiovascular dysfunction, and enhances balance and motor coordination in middle-aged mice. The study also found that resveratrol induces gene expression patterns similar to those induced by dietary restriction.
Adults with type 2 diabetes who eat high-fat meals may experience immediate memory declines, but taking antioxidant vitamins with the meal can offset this effect. A study found that consuming healthy foods rich in fruits and vegetables is the best defense against cognitive decline.
Researchers discovered that turmeric-treated mice were less susceptible to developing Type 2 diabetes and showed reduced inflammation in fat tissue and liver. Curcumin's anti-inflammatory properties may lessen insulin resistance and prevent the disease.
A study published in JAMA found that treated type 2 diabetes is associated with a higher risk of developing depression, while untreated diabetes has no significant link. The study suggests that psychological stress from managing diabetes may contribute to elevated depressive symptoms.
Researchers found a strong association between human herpesvirus 8 (HHV-8) infection and ketosis-prone type 2 diabetes mellitus (DM-2) in persons from sub-Saharan Africa. HHV-8 antibodies were present in 87.7% of patients with DM-2, compared to 15.1% of those without the condition.
A new study published in JAMA found that patients with depression are more likely to develop type-2 diabetes, and those with type-2 diabetes are also at a higher risk for developing depression. The study used data from the Multi-Ethnic Study of Atherosclerosis (MESA) to investigate this connection.
Adults with diabetes are more likely to experience hearing loss due to the disease's impact on nerves and blood vessels in the inner ear. Researchers discovered a strong association between high-frequency sound sensitivity and diabetes, which may be linked to nerve damage and increased risk of heart disease.
A new study found that some patients with type 2 diabetes can maintain good blood sugar control for years using non-insulin oral diabetic medications. The study of 191 veterans showed that 55% of patients remained on oral drugs and achieved improved hemoglobin A1c levels.
Women with type 2 diabetes and heart disease have poorer control of both diseases and receive less intensive medical treatment than do men. Women are also more likely to have uncontrolled high blood pressure and poor long-term control of their blood glucose levels compared to men.
Alogliptin demonstrated significant reductions in hemoglobin A1c (HbA1c) levels in patients with type 2 diabetes, particularly when used as monotherapy or added to existing oral anti-diabetic treatments. The study results suggest alogliptin is a effective treatment option for patients with inadequate blood sugar control.
A study by the University of Southern California suggests that abdominal fat releases lipids directly to the liver at night, leading to insulin resistance and increasing the risk of type 2 diabetes. The findings highlight the importance of abdominal obesity in the pathogenesis of the disease.
Recent research highlights the close relationship between type 2 diabetes and sleep apnea, with significant implications for public health and individual well-being. The IDF recommends screening, treatment, and further research to address this link.
Recent research shows a strong connection between type 2 diabetes and sleep apnea, with up to 40% of OSA patients having diabetes. IDF recommends education and screening for both conditions, as well as weight reduction, CPAP treatment, and further research.
Researchers found that intensively lowering blood sugar to near-normal levels did not significantly reduce the risk of major cardiovascular events, but increased the risk of death. The intensive strategy group had a 22% higher risk of death compared to the standard group.
A study of ongoing randomized clinical trials in diabetes reveals that only 20% have primary outcomes important to patients, such as illness, pain, or death. The researchers emphasize the need for a standard set of patient-important outcomes in diabetes trials to improve their informativeness.
A lifestyle intervention trial will determine optimal ways to translate research-developed programs to real-life settings in Chennai, India. The study aims to promote health behaviors, improved diet, weight loss, and increased physical activity to prevent diabetes in those at risk.
A collection of state-of-the-art reports highlights the benefits of self-monitoring blood glucose (SMBG) in achieving improved glucose control. SMBG has been shown to significantly improve glucose control, complements A1C results, and guides patient self-management of diabetes at home.
Research suggests that high-flavanol cocoa can improve blood vessel function in people with type 2 diabetes, rivaling the benefits of exercise and common medications. Flavanols may help increase nitric oxide production, reducing artery stress and promoting cardiovascular health.
A randomized controlled trial found that early intensive insulin therapy improved blood glucose control and β-cell function in patients with newly diagnosed type 2 diabetes. The treatment, which included continuous subcutaneous insulin infusion or multiple daily insulin injections, resulted in higher remission rates and prolonged glyc...
A pilot study will be conducted in Vinh City, Vietnam, to screen people at high-risk for pre-diabetes and diabetes. The screenings will be coupled with community awareness and healthy living programs to promote a lifestyle modification program over three months.
The International Diabetes Federation is funding the STOP Diabetes project to address lifestyle-related metabolic diseases and promote healthy behaviors. The project aims to reduce the risk of type 2 diabetes in women by encouraging healthy behaviors.
Research using a rat model of intrauterine growth retardation found reduced Pdx1 expression in pancreatic beta-cells throughout life following IUGR. The molecular mechanisms affecting Pdx1 expression were reversible in the fetus and after birth, but irreversible in adulthood, providing new insight into diabetes development.
A Kaiser Permanente study found that diabetes more than doubled in six years among teenage and adult women before becoming pregnant. The largest study to date examined 175,000 teenage girls and adult women, revealing significant jumps in pre-pregnancy diabetes in every age, racial, and ethnic group.
Researchers found high levels of E-selectin, white blood cells, and low serum albumin levels are clear predictors of high risk for type 2 diabetes. The study used data from the Western New York Health Study and found that combining these markers increased identification of high-risk patients by 8%.
A recent meta-analysis of 15 studies involving over 70,000 participants identified six new genes linked to type 2 diabetes. The study, published in Nature Genetics, confirms that insulin-producing cells play a crucial role in the disease's development.
Two studies suggest that Diabetinol, a natural citrus supplement, improves blood glucose numbers and LDL-cholesterol levels in people with type 2 diabetes. The supplement shows promise in lowering blood glucose levels after meals and improving heart health, potentially reducing diabetic complications.
Researchers at Michigan Technological University have developed a powerful tool to pinpoint the genes behind inherited illnesses. By analyzing data from over 1,000 people with and without type 2 diabetes, they identified 11 single nucleotide polymorphisms associated with the disease.
A clinical trial using IVUS technology found that Actos reduced the atherosclerotic burden in coronary arteries compared to glimepiride, and prevented progression. The study adds to the body of cardiovascular data for Actos, showing no evidence of increased risk of heart attack or stroke.
Researchers found that people with diabetes have the same high risk for heart attack or stroke as those who've already had a heart attack. The study suggests that all patients with diabetes receiving glucose-lowering treatment are at a particularly high risk of cardiovascular death and disease, regardless of sex and diabetes type.
A new study suggests that taking pioglitazone can help slow the progression of plaque build-up in coronary arteries, which is particularly aggressive in patients with diabetes. The findings have important implications for managing patients with type 2 diabetes and coronary artery disease.
Regular Tai Chi Chuan exercise improves T cell helper function in patients with type 2 diabetes by increasing T-bet transcription factor and IL-12 production, suggesting a potential therapeutic effect. The study also found improved glycemic control, reduced inflammation, and enhanced immune response.
A team of researchers has discovered six new genetic variants associated with an increased risk of type 2 diabetes, bringing the total number of genetic risk factors to 16. The study used combined genetic data from over 70,000 people and provides new clues to the processes that go wrong when diabetes develops.
Scientists at the University of Michigan have identified six new genes that play a role in type 2 diabetes, including one also linked to prostate cancer. The study provides insights into the mechanisms controlling glucose levels in the blood, offering potential new methods for preventing or treating the disease.
A collaborative effort by over 90 researchers from 40 centres analysed genetic data from 70,000 people to identify differences in the genetic code that make some individuals more susceptible to type 2 diabetes. The study found six new genes contributing to the risk, bringing the total to sixteen, and provides valuable insights into the...
A study published in Diabetes Research & Clinical Practice found that people with depression taking antidepressants have a 30% increased risk of developing type 2 diabetes. The risk was highest for those using two types of therapies simultaneously, such as tricyclic antidepressants and selective serotonin reuptake inhibitors.
The UMDNJ-University Hospital has received a grant to tailor interventions and personalize the transition from hospital to outpatient clinic for patients with type 2 diabetes. The project aims to reduce hospital emergency department visits, inpatient readmissions, and improve health-related quality-of-life and metabolic control.
A recent study found that weight loss and major lifestyle changes are more effective in treating type 2 diabetes than intensive insulin therapy. Insulin resistance, caused by high-calorie diets, can lead to organ damage and increase the risk of complications such as heart disease and blindness.
A new study proposes that intestinal dysfunction, specifically in the upper small intestine, may be the source of Type 2 diabetes. Surgical bypass operations can reverse this abnormality, leading to diabetes remission.
Researchers found that Asian Indians have higher insulin resistance and mitochondrial function than Northern Europeans, despite being non-obese. This study suggests that urbanization and diet changes may contribute to the increased risk of type 2 diabetes in Asian Indians.
A new study found elevated markers of blood vessel inflammation in overweight Hispanic children with normal blood glucose levels, increasing their risk for type 2 diabetes and cardiovascular disease. The research highlights the need for obesity prevention strategies tailored to this high-risk population.