Articles tagged with Schwann Cells
Researchers at the University of Rochester Medical Center have discovered that dorsal root ganglion neurons can create thick, healthy nerves without provoking an immune response. This breakthrough could lead to better treatment options for the over 350,000 patients with serious nerve injuries in the US each year.
A $1.4 million NIH grant will investigate a method to heal peripheral nerve damage by stimulating the growth of Schwann cells and axons, potentially restoring function in patients with severe injuries. Researchers aim to develop effective tools for nerve repair using electrical stimulation technologies.
A new study suggests that regenerative abnormalities associated with diabetes are widespread, affecting not only nerves but also blood vessel growth and Schwann cell proliferation. By promoting blood vessel and Schwann cell growth, researchers may be able to speed up axon regeneration and repair damaged nerves and blood vessels.
Researchers at UNC Chapel Hill pinpointed Erk as crucial for nerve fiber insulation with myelin, allowing signals to be sent between brain and limbs. This discovery informs study of neurodevelopmental disorders like neurofibromatosis, where Schwann cells grow unregulated.
Researchers have identified the genetic marker for Devil Facial Tumour Disease (DFTD), a transmissible cancer affecting only Tasmanian devils. The discovery reveals that DFTD originates from Schwann cells, which protect peripheral nerve fibres.
Guided fat precursor cells lead to wider nerves and less muscle atrophy in injured peripheral nerves of laboratory rats. The study demonstrates the potential benefit of adult precursor cells, such as those from adipose tissue, for nerve repair and functional recovery.
Researchers at Purdue University have developed a novel technique using spun-sugar filaments to create synthetic tubes that mimic natural nerves. The scaffolds can promote nerve regeneration by acting as bridges between severed nerves, and may also be used to repair blood vessels damaged by disease.
A UK research team discovered a new molecular cue that promotes limb regeneration in newts, which could help guide the field of regenerative medicine. The finding was recognized with the 2008 AAAS Newcomb Cleveland Prize.
UT Southwestern researchers found that tumors growing around nerves require cooperation from immune cells to grow. A new therapy targeting the immune system has shown promising results in treating previously untreatable tumors.
Researchers at Peninsula Medical School have identified a protein called c-Jun that plays a vital role in the regeneration of damage in the peripheral nervous system. This discovery could lead to understanding and treating diseases such as Charcot-Marie-Tooth disease and Guillain-Barre disease.
Researchers found that activating the c-Jun gene in cultured neurons with Schwann cells promotes dedifferentiation and speeds nerve healing. The study suggests a new potential target for understanding and treating diseases like Charcot-Marie Tooth disease and Guillain-Barre syndrome.
Researchers at Kyoto University School of Medicine successfully regenerated damaged nerves using bone marrow cells containing adult stem cells. The transplanted cells differentiated into Schwann cells, promoting axon regeneration and healthier vascularity.
Haesun Kim's research focuses on Schwann cells and axon communication links in myelination, which may lead to remyelination and correction of neurological disorders. The study aims to pinpoint the sequence and nuances of communication links involved in myelination.
A new study has shed light on the mechanisms controlling myelin formation, a process crucial for efficient nerve communication. Researchers found that Par-3 acts as a molecular scaffold to organize key proteins essential for myelination.
Researchers at Brown University have developed a method to create plastic replicas of real cells, which can support cell growth and potentially be used in laboratories and hospitals. The replicas could help scientists understand nerve growth and repair damaged tissue, and may eventually be used to regenerate nerves in patients.
Researchers at SickKids have discovered that stem cells found in adult skin can generate Schwann cells that can myelinate demyelinated axons and provide a growth environment for injured central nervous system axons. This breakthrough has the potential to treat nerve injuries, demyelination disorders such as multiple sclerosis, and spin...
Researchers identify neuregulin gene as key factor in myelin production, enabling faster neural transmission. The discovery opens possibilities for repairing damaged spinal cords and brain tracts.
Researchers found that a combination therapy using Schwann cells and cyclic AMP (cAMP) promotes axonal growth and functional recovery after spinal cord injury. The treatment preserved and elevated cAMP levels in nerve cells and myelinated nerve fibers, leading to better locomotion and coordination in rats.
Researchers found that a muscle protein called dystroglycan plays a crucial role in forming normal myelin sheaths, which allow nerves to transmit signals efficiently. The study suggests that disruption of this protein may contribute to various neuropathic disorders.
Researchers found that the leprosy bug attaches to Schwann cells, disrupting the myelin sheath and causing nerve damage. This discovery may provide insights into early molecular events of neurodegeneration processes in diseases like multiple sclerosis.
A team of researchers at Yale University successfully transplants Schwann cells into a patient's brain to repair damaged nerve fibers in Multiple Sclerosis. The procedure aims to restore normal function and has the potential to benefit millions of people affected by MS and other demyelinating diseases.