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Marijuana increases alcohol toxicity in young rats

A new study using rats found that THC combined with mildly intoxicating doses of alcohol induced widespread nerve cell death in the brain. The study also showed that THC enhanced the neurotoxic effect of other substances, including phenobarbital and MK-801.

SourceWiley·JournalAnnals of Neurology·DateApr 8, 2008

Heavy marijuana use linked to gum disease

A recent study has found that heavy marijuana use is associated with an increased risk of developing periodontal disease. The study, which tracked over 900 individuals, found that frequent cannabis use since age 18 was linked to more than one-third of new cases of gum disease between ages 26 and 32.

SourceDuke University·JournalJournal of the American Medical Association·DateFeb 5, 2008

Regular marijuana use increases risk of hepatitis C-related liver damage

Patients with chronic hepatitis C infection who use cannabis daily are at higher risk of moderate to severe liver fibrosis. Cannabis use combined with heavy alcohol consumption significantly increases the risk of liver damage. The American Gastroenterological Association recommends avoiding cannabis use in patients with HCV.

SourceAmerican Gastroenterological Association·JournalClinical Gastroenterology and Hepatology·DateJan 28, 2008

Gauging parent knowledge about teens' substance use

Detailed statistics show that 82% of parents accurately evaluated cigarette smoking, 86% accurately reported alcohol use, and 86% accurately reported marijuana use. However, only 72% accurately reported illicit drug use. Parents can use this knowledge to help themselves cope with teenage substance use.

SourceUniversity at Buffalo·JournalJournal of Child & Adolescent Substance Abuse·DateOct 24, 2007

Mailman School of Public Health study examines link between racial discrimination and substance use

Researchers found African Americans experiencing racial discrimination more likely to report current tobacco use, recent alcohol consumption, and lifetime use of marijuana and cocaine. This association was also seen in Whites, suggesting that substance use may be an unhealthy coping response to perceived unfair treatment.

SourceColumbia University's Mailman School of Public Health·JournalAmerican Journal of Epidemiology·DateAug 20, 2007

Long-term marijuana smoking leads to respiratory complaints

A new study by Yale University researchers found a link between long-term marijuana smoking and respiratory complications, including obstructive lung disease. The study's findings suggest that patients should be advised of the potential negative impact on overall lung health despite methodological limitations.

SourceYale University·JournalArchives of Internal Medicine·DateFeb 12, 2007

Marijuana relieves HIV nerve pain

A study published in Neurology found that smoking marijuana reduced nerve pain in people with HIV-associated sensory neuropathy by 34%, compared to 17% for those who received a placebo. The study also showed significant relief from chronic pain, with an average reduction of 72%.

SourceAmerican Academy of Neurology·JournalNeurology·DateFeb 12, 2007

Parental cigarette use is 'double whammy' for children

A new study from the University of Washington found that children of smokers are more likely to smoke, binge drink or use marijuana in adolescence and adulthood. The study also discovered a link between substance use by parents and their children's behavior problems, with a transmission link observed across generations.

SourceUniversity of Washington·JournalJournal of Abnormal Child Psychology·DateAug 10, 2006

Marijuana use causes early pregnancy failure

A new study in mice reveals that marijuana use at conception and early pregnancy can cause embryos to fail to reach the uterus, resulting in early pregnancy failure. The study found that THC, a major psychoactive component of marijuana, disrupts anandamide signaling, leading to impaired fertility and ectopic pregnancies.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateAug 1, 2006

Teens turn to pot after parental bust-ups

A new study by the University of Queensland research has found a link between cannabis use and marital changes in children up to age 21. Children who experienced more frequent changes in their parents' marital status were more likely to report cannabis use, with almost half having used cannabis at some point.

SourceResearch Australia·JournalInternational Journal of Epidemiology·DateApr 3, 2006

New antidepressant drug increases 'brain's own cannabis'

Researchers have discovered a new drug that raises the level of endocannabinoids, providing measurable antidepressant effects. The study found similar results to commonly prescribed antidepressants, suggesting URB597 as a safer, non-addictive alternative for pain and depression treatment.

SourceMcGill University·JournalProceedings of the National Academy of Sciences·DateDec 13, 2005

Problem gamblers share personality profiles of substance abusers

Researchers identified a striking similarity in personality traits between problem gamblers and individuals with alcohol, cannabis, and nicotine dependence. Young adults with problem gambling diagnoses tended to exhibit negative emotions, impulsive behavior, and risk-taking tendencies, suggesting a common underlying profile.

SourceJAMA Network·JournalArchives of General Psychiatry·DateJul 4, 2005