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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Site of the next major earthquake on the San Andreas Fault?

Researchers discover highly faulted and organized 'Durmid ladder structure' in southern California, which could be nucleation site for next M>7.5 earthquake on the San Andreas Fault. The structure is at least 25 km long and features tens of master faults along its edges.

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New cellular insights in bone development

A team of engineers at Washington University in St. Louis studied the formation of new bone and teeth, discovering that miniscule gaps in collagen's fiber structure facilitate the nucleation of calcium phosphate. The findings provide a new view into the current theory of calcium phosphate nucleation in confined spaces.

Molecular details of protein crystal nucleation uncovered

A team of scientists has uncovered the molecular details of protein crystal nucleation, a process with great medical and scientific relevance. They developed a new methodology to study this elusive system, providing insights into polymorph selection and guiding the crystallization process to produce desired crystal forms.

GoPro HERO13 Black

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Location matters in the self-assembly of nanoclusters

Researchers at Iowa State University have developed a theoretical framework to understand the relationship between capture zones and the formation of nanoclusters. The study highlights the importance of subtle spatial details in the nucleation process, which is crucial for controlling nanostructure properties.

How water droplets freeze: The physics of ice and snow

A team of researchers proposes a new question on the crystallization of water in droplets, finding that density waves are excited before crystallization. The study uses computer simulations to investigate the freezing of nanoscale silicon drops and films, providing new insights into the formation of ice and snow.

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Molecular inhibitor breaks cycle that leads to Alzheimer's

Researchers have identified a molecular chaperone that can break the critical cycle leading to Alzheimer's disease. The molecule, Brichos, inhibits secondary nucleation, preventing the formation of toxic oligomers and amyloid fibrils, which are hallmark of the disease.

Birth of a mineral

Researchers used a powerful microscope to study the birth of crystals in real time, revealing that calcium carbonate forms into different minerals through various pathways. This discovery may help scientists understand how to lock carbon dioxide out of the atmosphere and better reconstruct ancient climates.

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Biologists take snapshot of fleeting protein process

Researchers have captured the first three-dimensional crystalline snapshot of the initial step in actin filament formation, crucial for understanding cell shape and cancer. The study's dual-mutant approach helped overcome challenges in forming crystals, revealing critical contacts involved in nucleation.

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Microbes may be engineered to help trap excess CO2 underground

Researchers at Lawrence Berkley National Laboratory's Center for Nanoscale Control of Geologic CO2 have engineered bacteria to speed up the formation of solid carbonate minerals, which can permanently trap carbon dioxide. This process could help remove excess CO2 from the atmosphere and mitigate global warming.

Findings suggest nanowires ideal for electronics manufacturing

Silicon nanowires show highly repeatable nucleation process, allowing for predictable growth and design of electronic systems. The research could enable the continuation of Moore's law by providing a new manufacturing method for nanowire-based electronics.

New insight to demineralization

Scientists at Virginia Tech have found a novel mechanism for demineralization of noncrystalline silicas, which can dissolve up to 100 times faster than expected. This breakthrough has significant implications for the development of biomedical implants and synthetic materials with bone-like properties.

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New finding bubbles to surface, challenging old view

Chemical engineers discovered a fundamental flaw in the conventional view of how liquids form bubbles that grow and turn into vapors. The new findings apply to homogeneous nucleation and suggest multiple possible pathways for phase transition, potentially leading to practical safety benefits for industry.

Traces of nanobubbles determine nanoboiling

The study reveals that nanobubbles formed by the collapse of one bubble become new nucleation sites for later bubbles, allowing them to form earlier and at lower temperatures. This discovery may impact technologies such as inkjet printing and thermal cancer therapies.

NASA experiments validate 50-year-old hypothesis

Researchers used NASA's Electrostatic Levitator to prove a 50-year-old hypothesis on nucleation, a process crucial for materials and biological systems. The study showed that liquid metals resist turning into solids due to an atomic 'nucleation barrier', a fundamental mismatch in atom arrangement.

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