Articles tagged with Organic Synthesis
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at FEFU developed a new synthetic derivative of fascaplysin with enhanced antitumor activity, demonstrating 2-3 times higher efficacy against cervical cancer and monocytic leukemia cells. The study also uncovered a novel alkaloid, 6-oxofascaplysin, derived from indigo.
Researchers at Kanazawa University have successfully synthesized a ketone from an aldehyde using the synergistic action of an organocatalyst and a palladium catalyst in one flask. This novel protocol enables simple and mild synthesis under conditions that previously required complex chemical reaction steps or metal reagents.
Chemists at Emory University have developed a new catalyst that selectively activates a carbon-hydrogen bond without using a directing group. The breakthrough holds promise for the pharmaceutical industry and could lead to new classes of drugs.
Researchers at RUDN University have developed a new method for creating drug molecules using carbon monoxide as a reducing agent. This innovation offers an energy-efficient solution to producing valuable chemicals, potentially reducing waste and costs. The study's findings suggest that this technology could be used in the synthesis of ...
Researchers have developed a copper-catalyzed double hydroboration method to synthesize internal gem-diborylalkanes. The approach restricts regioselectivity with carbonyl groups, overcoming previous challenges with internal alkynes.
Researchers successfully synthesized a carbon nanobelt, measuring 0.83 nm in diameter, using a novel synthetic strategy based on a macrocycle precursor. The breakthrough opens a new field of nanocarbon science and has potential applications in electronics and photonics.
Chemists at FAU have developed a novel synthetic route towards antiviral quinazoline heterocycles using metal-free domino processes. This approach reduces lab work time, costs, and waste, while creating new compounds with intrinsic fluorescence properties.
A team of researchers at Princeton University has devised a novel pathway for reactivity that bypasses the need for reactive functional groups. The method uses proton-coupled electron transfer to form valuable carbon-carbon bonds, opening up new synthetic opportunities.
The IBS team developed a novel approach to synthesize carbon nanostructures by embedding lanthanum ions in zeolite pores, resulting in graphene-like materials with high electrical conductivity. This efficient synthesis strategy enables the scalable production of carbon nanostructures for various applications.
Researchers from Hiroshima University have developed a new re-chargeable battery that can operate at below-freezing temperatures, making it suitable for use in refrigerated factories or extreme winter environments. The eco battery has the potential to be cheaper, safer, and longer-lasting than current metal-based batteries.
Researchers have developed a method to selectively functionalize unreactive carbon-hydrogen bonds in alkanes, a key step towards revolutionizing organic synthesis. The breakthrough enables the transformation of simple molecules into valuable chemicals with controlled site selectivity and chirality.
Researchers have created a safer and more efficient water-based system for synthesizing organic compounds, reducing reliance on volatile organic solvents and improving environmental sustainability. The new process also produces higher yields of product and allows for easy separation and extraction of the final compound.
Matthew Disney, a professor at Scripps Research Institute, has won the Tetrahedron Young Investigator Award for his exceptional creativity and dedication to organic synthesis and bioorganic and medicinal chemistry. The award recognizes his lab's work on tackling difficult problems in biomedical science.
The European Union is funding a research structure concept called ELYSION to advance electroconversion and electroactive materials in Mainz. The lab will focus on sustainable methods of synthesizing materials and chemical compounds using electricity as a catalyst.
Researchers discovered cesium carbonate generates an aggregate state that acts as the starting point for catalytic reactions. This finding has the potential to impact C-H functionalization reactions and catalytic reaction development.
Researchers at Moscow Institute of Physics and Technology have developed a new method for synthesizing ultrahard fullerite, a material with hardness values ranging from 150 to 300 GPa, surpassing diamond. The breakthrough synthesis requires lower pressures and can be achieved at room temperature, enabling industrial-scale production.
Direct C–H transformations aim to perform synthetic chemistry in a greener and more atom-economical way. Several generations of chemists collectively made significant progress in inert aliphatic C–H bond functionalization.
The Emory Center for Selective C-H Functionalization aims to break new ground in organic synthesis, making it faster, simpler, and greener. The center's research is poised to help C-H functionalization enter the mainstream of organic chemistry.
Researchers at LMU München have developed a facile route to versatile organozinc compounds by synthesizing them as salt-stabilized solids. This allows for easier storage and transportation compared to traditional liquid forms, making them more suitable for industrial applications.
Krzysztof Matyjaszewski will be recognized for his groundbreaking research in synthesis of organic materials and controlled radical polymerization. His work has led to the development of innovative materials with tailored functionalities, enabling applications in energy, environment, and biomedicine.
Researchers at University of Cincinnati developed a novel composite catalyst and optimal synthesis conditions to grow extremely long aligned carbon nanotube arrays. The longest array reached 18 mm in length, opening doors to potential applications in nanomedicine, aerospace and electronics.
Danishefsky's work has provided major fundamental advances in organic synthesis and impacted the treatment of cancer, with novel compounds currently in clinical trials. He is recognized as one of the world's leading chemists and a celebrated researcher, with numerous awards and honors including the Wolf Prize in Chemistry.
Glenn Micalizio, Yale Assistant Professor, has been awarded the Eli Lilly Grantee Award for his research on simplifying organic chemistry. His work focuses on developing new methods for forming carbon–carbon bonds to facilitate drug discovery.
The Beilstein Journal of Organic Chemistry publishes full research articles on various aspects of organic chemistry. Authors can submit their work online and retain copyright without publication charges.
Researchers at UIC successfully synthesized the rare molecule laulimalide, a potent anticancer compound with potential to surpass existing cancer drug Taxol. The stepwise synthesis allows for control of stereochemistry, enabling testing of variants with enhanced antitumor activity.
A breakthrough in basic chemistry developed by University at Buffalo scientists has the potential to expand dramatically the variety and potency of new pharmaceutical compounds. The method uses a chiral catalyst to synthesize biologically important compounds with specific chemical structures.