Articles tagged with Control Groups
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Scientists have discovered unique periodic structures in manganese germanide that behave like magnetic monopoles and antimonopoles. The researchers studied the collective excitation modes of these structures, revealing a way to experimentally determine their spatial configuration.
A new WhatsApp-based program has shown significant improvements in treating depression among older adults in Brazil. The Viva Vida program used simple audio messages and images to provide education on depression and behavioral activation, with a 10-point improvement in symptom reduction between intervention and control groups.
A new study led by researchers at UC San Francisco found that a virtual emotion-centered program called TunedIn can reduce diabetes distress by half and improve glucose control. The program incorporates elements of Acceptance and Commitment Therapy and was delivered virtually to 276 adults with Type 1 diabetes.
A study found that low doses of filtered kretek cigarette smoke altered rat lung histometric measurements, increasing the size of respiratory bronchioles. P53 gene overexpression was also observed in response to exposure. The findings suggest potential health risks from even low levels of kretek cigarette smoke.
Researchers at the State University of Campinas found that daily consumption of jaboticaba peel improved glucose metabolism even after meals. The study showed lower post-prandial glycemia and less inflammation in volunteers with obesity and metabolic syndrome.
Researchers have developed a new weight loss drug that combines GLP-1 with molecules blocking the NMDA receptor, exploiting its effects on appetite control and neuroplasticity. This approach shows promise for greater weight loss in mice than existing medications.
A study published in JAMA Surgery found that bariatric surgery significantly reduces the risk of breast cancer in women with obesity, particularly those with high blood insulin levels. The results show a 32% lower risk overall and a 52% lower risk for women with high insulin levels at the start of the study.
A new study shows that text messaging with financial incentives significantly improves weight loss in men with obesity compared to traditional methods. The intervention combines personalized text messages with cash rewards, resulting in a 5% weight loss threshold, and could be an effective low-cost solution for health services.
A research team at Kyoto University found that interactive AI programs can reduce prejudice and anxiety among historically divided ethnic groups in Afghanistan during online interactions. Participants in the AI intervention group showed more engagement and significantly less prejudice and anxiety compared to the control group.
A research team at Waseda University has discovered a family of poly(thiourea)s (PTUs) with exceptional optical properties, including transparency over 92% and a refractive index of 1.81. The polymers can be easily degraded into simpler molecules, making them suitable for sustainable optoelectronic applications.
Scientists at DTU and Lund University have found new enzymes that can remove both the A and B blood antigens and their blocking sugars, enabling the production of universal donor blood. This breakthrough has the potential to reduce logistics and costs associated with storing four different blood types.
Researchers investigate the neuroprotective effects of tocotrienols in alleviating obesity-induced cognitive decline. The study found that T3s treatment improved cognitive function and mitigated oxidative stress in mice fed with a high-fat, high-sucrose diet.
A team of researchers has successfully integrated a metasurface with photonic integrated circuits, enabling fast and tunable control over light manipulation. The device can shape any wavefront in reconfigurable arbitrary polarization states at speeds of up to 1.4 gigahertz.
A study published in Psychiatry Research confirms that weight training improves symptoms of anxiety and depression in old people. The analysis of over 200 articles identified the types of training most indicated for these cases, recommending exercises done three times a week with short sets and proper structure.
A recent study published in JAMA Network found no association between acetaminophen use during pregnancy and increased risk of autism, ADHD, or intellectual disability in offspring. The study suggests that familial confounding may have contributed to previous associations observed in other models.
Researchers visualize chiral interface state at atomic scale for the first time, allowing on-demand creation of conducting channels. The technique has promise for building tunable networks of electron channels and advancing quantum computing.
Researchers developed novel optimal and robust-optimal controllers for the FDS model, achieving six-fold reduction in settling time and improved stability. The robust-optimal controller performed better than the optimal controller in simulations with noise, demonstrating its adaptability.
Patients with post-COVID condition exhibit lower aerobic capacity and muscle strength compared to control groups, indicating potential benefits of cautious exercise regimens. The study highlights the need for personalized exercise recommendations to mitigate further skeletal muscle deconditioning in PCC patients.
Black and Hispanic individuals received fewer telemedicine visits than white individuals after controlling for geographic region, contrary to national trends. The study suggests systemic inequalities in access to telemedicine care exist despite increased use during the pandemic.
A new study evaluates the use of tirzepatide in overweight/obese adults with type 1 diabetes, showing significant weight loss and improved glucose control. Tirzepatide also reduces insulin dose and increases time-in-range on continuous glucose monitoring.
A high-touch pharmacy care management program leads to lower pharmacy spending costs, decreased inpatient hospital stays and optimal medication use. The study found that such a program can help Medicare Advantage members save money and improve their health outcomes.
A study of routine fecal occult blood testing found a significant decrease in colorectal cancer mortality in Sweden. The association between screening and reduced mortality is expected to be higher due to co-existing testing and delayed diagnoses.
A study published in Global Change Biology found that low deep-water oxygen concentrations lead to increased algae growth and further oxygen declines. This positive feedback cycle can result in frequent algal blooms, disrupting lake ecosystems and human health.
Researchers develop nanovector nanogels that selectively target glial cells involved in spinal cord injury inflammation, reducing damage and improving recovery. The treatment demonstrates potential for modulating glial cells in neurodegenerative diseases like Alzheimer's.
A Chinese Medical Journal study examined the spatiotemporal features of disease burden due to air pollution across China between 2005 and 2017. The findings revealed a downward trend in premature mortality from fine particulate matter (PM2.5) and ozone (O3) pollution, but an increasing financial burden due to economic growth.
A new study from the University of Notre Dame found that female entrepreneurs in emerging markets benefit significantly more from having a female mentor, with firms' performance improving by 32% and 31%. Female mentors proved to be more positive and social in their interactions, helping businesswomen build better customer relationships.
Researchers have developed a novel optical neural network architecture that achieves nonlinear optical computation by precisely controlling ultrashort pulse propagation in multimode fibers. This approach streamlines the need for energy-intensive digital processes, achieving comparable accuracy with significantly reduced parameters.
Researchers found that the life expectancy of AIAN individuals is seven years less than that of White populations, with rapid increases in suicide mortality rates between 1999 and 2020. The study suggests historical trauma and ongoing inequality contribute to high suicide rates among AIAN people.
A new study using an animal model has identified a window of opportunity for early treatment to promote long-term control and remission of HIV infection. Starting treatment four weeks after infection promotes viral control after discontinuation of treatment, highlighting the importance of early diagnosis and treatment.
Rheumatoid arthritis patients who underwent a single session of aerobic exercise experienced temporary reductions in blood pressure at rest and under stress. The study, conducted at the University of São Paulo, demonstrates the benefits of moderate-intensity walking for cardiovascular management and blood pressure control.
A phase III study found that selpercatinib significantly improves cancer progression-free survival in patients with NSCLC and RET gene translocations. The therapy also demonstrated efficacy in treating intracranial lesions, a common challenge in advanced NSCLC.
A large randomized study investigated the effect of preoperative, low-dose oral administration of midazolam in older patients on patient satisfaction and safety. No significant difference was found between midazolam and placebo groups regarding patient safety.
Researchers have discovered a new control mechanism that drives the maturation of human stem cell-derived heart muscle cells, providing fresh insight into cardiac regenerative therapy and disease modeling. The study identifies RBFox1 as a key intrinsic regulator of heart muscle cell maturation.
A study found that over 13% of cancer drug trials in China used suboptimal control arms, which may lead to biased results and patient harm. The researchers highlight the need for refining trial design to generate optimal clinical evidence.
A study published in the Journal of Nursing Administration found that Transcendental Meditation significantly reduced PTSD, anxiety, and burnout in frontline nurses during the COVID-19 pandemic. The technique improved flourishing by 15% and decreased symptoms by more than half over a 3-month period.
Researchers found that practice interventions for improving integrated behavioral health (IBH) activities had a minimal impact on patient outcomes. However, practices that completed the intervention and those with higher IBH levels showed improved patient outcomes.
Researchers from the Amsterdam University Medical Centre conducted a study on patients who choose to voluntarily stop eating and drinking (VSED) to hasten death. They identified three distinct groups: older patients seeking control over their lives, care-dependent patients with poor quality of life, and younger psychiatric patients. Th...
Researchers found that immunomodulatory drugs used to treat rheumatoid arthritis can reduce the risk of autoimmune thyroid diseases. Patients treated with these drugs had a 46% lower risk of developing an autoimmune thyroid disease compared to those without rheumatoid arthritis.
Researchers found that acoustic stimulation improved postconcussive symptoms in individuals with mild traumatic brain injury, although the benefits were largely sustained. The study's results suggest that listening to acoustic stimulation based on brain electrical activity may not improve symptoms more than randomly generated sound sti...
Researchers at University of California - San Francisco find that sense of taste signals brain to slow down eating. Using advanced techniques, they recorded brain activity in awake mice and found PRLH neurons controlled by mouth signals when eating normally, not gut signals as previously thought.
A study found that pregnant women with high blood pressure who received tight blood pressure control immediately after pregnancy had lower blood pressure levels and improved cardiac function compared to those with usual care. This could lead to a reduced risk of cardiovascular disease, including heart attacks and strokes.
Patients with post–COVID-19 chemosensory alterations experience improved recovery of smell function over a 3-year period. Taste dysfunction shows lower frequency and faster recovery compared to smell dysfunction.
Researchers have successfully excited a scandium-45 nuclear isomer using X-ray pulses, paving the way for the creation of the world's most precise clock. The breakthrough has significant implications for fields such as nuclear physics, satellite navigation, and telecommunications.
A study led by Brown University researchers found that mindfulness-based blood pressure reduction programs improve health behaviors associated with lower blood pressure. Participants in the program showed significant improvements in adherence to a heart-healthy diet and self-awareness, which influences dietary choices.
A recent study by the University of Gothenburg found no correlation between post-COVID condition and ongoing viral infection or active brain damage. The study analyzed 25 participants with confirmed post-COVID condition, six without residual symptoms, and 17 control subjects, revealing undetectable SARS-CoV-2 antigens in all samples.
A study at Washington State University found that implicit bias training improved police behavior toward homeless individuals, particularly in terms of offering polite greetings and de-escalating volatile situations. The trained officers also reported 50% fewer discrimination complaints overall.
Researchers at the University of Illinois have developed a procedure for measuring ytterbium-171 qubits that preserves them for future use, enabling long multistage calculations and multistage operations. This breakthrough paves the way for scalable neutral atom quantum computing.
A new study published in the Journal of the American Heart Association found that chronic kidney disease may increase the risk of sudden cardiac arrest among Hispanic/Latino adults. Heavy drinking and preexisting heart disease were also linked to an increased risk of sudden cardiac arrest.
A recent study published in Journal of Advertising sheds light on the effects of in-stream video advertising on ad information encoding. The research found that mid-roll ads elicit negative emotions but do not affect viewers' purchase intention. In contrast, pre- and post-roll ads have a significant impact on memory formation, highligh...
Researchers found that preschoolers from low-income families had poorer health outcomes and improved less in healthy lifestyle habits compared to their peers from more affluent backgrounds. The intervention program showed significant improvements in knowledge, attitudes, and behaviors among children with higher socioeconomic status, bu...
Accelerometer sensors can detect sickness behavior in wild boar, allowing for early detection of African Swine Fever. The study found that infected boars were 10-20% less active daily than healthy ones, making this technology a potential tool for disease control and prevention.
A meta-analysis of 34,000 older adults found that antihypertensive treatment decreased dementia risk compared to untreated hypertension. Individuals with treated hypertension had no increased risk of dementia.
A new study found that the Food Sensations for Adults program effectively improves food literacy behaviors and dietary habits in participants aged 18 and older. The program's sustained behavioral change is comparable to other similar programs, with notable improvements in vegetable servings and cooking confidence.
A 12.3% increase in blood pressure control was achieved among at-risk populations through community-based, self-measured blood pressure control programs. These programs, implemented in partnership with patients and healthcare professionals, utilized evidence-based interventions to address the needs of disproportionately affected groups.
A new remote digital monitoring program improved blood pressure control rates in over half of patients, highlighting its potential to improve outcomes and decrease heart attacks and strokes. The study found significant improvements when combining digital monitoring capabilities with clinical feedback.
Researchers at UCLA have found that embedding study recruitment in pre-appointment check-in pages can increase participation rates up to 40 times higher than traditional methods. The new technique, called preCheck-in recruitment, resulted in a socio-demographically representative patient population without financial incentives or staff...
Researchers found a significant increase in pediatric trauma admissions during the COVID-19 pandemic, with younger patients and falls from moderate heights being more common. Blood alcohol levels were also higher in patients aged 14-18 years old, suggesting targeted interventions to curb alcohol use may be needed
A study published in Stroke found significant disparities in stroke risk factors between Black and non-Black adults. However, after one year of intensive medical intervention, some risk factors were reduced in Black adults.
A Cornell University study found that encouraging fact-checking on Reddit led to a drop in story rank by an average of minus-25 spots, causing stories to be missed by readers. The research suggests that collective efforts to improve information environments can influence algorithmic recommendations.
A new statistical tool, two-step synthetic control, allows managers and policymakers to estimate effects they previously couldn't accurately. The study found that this method estimated a more modest increase in weekly tampon sales after New York's repeal, better matching actual sales figures.