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Science News Archive January 2002 - Page 7


Page 7 of 7

A genetic basis for behavior in infancy

Research finds a genetic basis for behavior in infancy, linking attachment disorganization to dopamine D4 receptor gene polymorphisms. The study identifies specific variants that enhance the risk of disorganized attachment, supporting the role of DRD4 as a genetic susceptibility factor.

SourceMolecular Psychiatry·JournalMolecular Psychiatry·DateJan 7, 2002

Scientist finds genetic clues to Alzheimer's, establishes DNA bank for future studies

A researcher at Medical College of Georgia has identified three genetic flaws on chromosomes in patients with the most common type of Alzheimer's disease. Dr. Poduslo's study suggests that late-onset Alzheimer's is linked to multiple genes and may be subdivided into specific categories, leading to improved diagnosis and treatment options.

Diagnostic criteria for brain death vary worldwide

A comprehensive survey of brain death diagnosis in adults worldwide reveals significant variations in procedures, including differences in required physicians, observation time, and confirmatory tests. These discrepancies may be due to collective decisions by task forces or cultural attitudes, highlighting the need for standardization.

SourceAmerican Academy of Neurology·JournalNeurology·DateJan 7, 2002

UMAINE professor develops classification system for eastern and central U.S. winter storms

A University of Maine professor has developed a classification system to help weather forecasters and the public understand the likely impacts of winter storms. The system assigns an intensity index and category score based on air pressure and forward speed, providing insights into storm strength and duration.

SourceUniversity of Maine·JournalBulletin of the American Meteorological Society·DateJan 7, 2002

Exposing insects' sense of smell

A protein in an insect's antenna picks up chemical signals called pheromones and changes its shape to eject them onto sensitive nerve endings. This discovery could lead to the development of insecticides that prevent insects from detecting other chemical signals, essential for their survival.

SourceUniversity of California - Davis·JournalProceedings of the National Academy of Sciences·DateJan 3, 2002

Mechanisms of disease

The new section aims to explain the relevance of new research in genetics and molecular biology to practising clinicians. Key findings include associations between genetic sequences and disease, as well as the potential of proteomic analysis to further our understanding.

SourceThe Lancet_DELETED·JournalThe Lancet·DateJan 3, 2002

From matter waves to a crystal of atoms and back

Scientists have successfully created a crystal of atoms and observed a quantum phase transition, shedding light on fundamental problems in solid-state physics, quantum optics, and atomic physics. By increasing the strength of a microscopic lattice, researchers induced a transition from a superfluid phase to an insulating Mott phase.

SourceMax-Planck-Gesellschaft·JournalNature·DateJan 3, 2002

Siestas in space?

A NASA-funded study is investigating the effects of reduced sleep on astronauts in space, with a focus on finding optimal combinations of anchor sleep and daily naps. The research aims to mitigate cognitive impairments, improve reaction times, and enhance overall well-being among space travelers.

New treatment strategy for blood-clotting disorder

A French study found that intravenous immunoglobulin improved platelet counts in adults with AITP. The study also showed that oral steroids and placebo had similar efficacy rates. The researchers suggest judicious observation for patients without severe bleeding and recommend specific immune-based therapies.

SourceThe Lancet_DELETED·JournalThe Lancet·DateJan 3, 2002

NYU scientists advance toward nanorobots

Researchers have developed a robust DNA mechanical device that can manipulate movement within individual molecule pairs without affecting others. This breakthrough paves the way for nanorobotic applications and demonstrates a new level of control over molecular-scale devices.

SourceNew York University·JournalNature·DateJan 2, 2002

Monitoring epithelial plasticity, one cell at a time

Researchers monitor epithelial cell plasticity to understand its potential applications in tissue engineering and regenerative medicine. By analyzing individual cells, scientists can gain insights into how tissues adapt and respond to changing conditions.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJan 2, 2002

CNS cell death in bacterial meningitis

Infants and adults are susceptible to bacterial meningitis-induced CNS cell death, leading to severe neurological outcomes. Researchers investigated the underlying mechanisms of this devastating condition, shedding light on potential therapeutic targets for treatment and prevention.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJan 2, 2002

The anti-inflammatory effect of apoptotic bodies

Researchers explored the anti-inflammatory properties of apoptotic bodies in various diseases, including IBD and osteoarthritis. They found that these bodies can modulate immune responses and reduce inflammation, offering new therapeutic targets for treating chronic inflammatory conditions.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJan 2, 2002

Study finds that steroids soothe sore throat pain

Researchers found that steroid treatment reduced sore throat pain by four hours and increased relief to twice that of placebo patients. The study also showed significant cost savings due to the pill form, which eliminates the need for a physician or nurse to administer the shot.

SourceMayo Clinic·JournalThe Laryngoscope·DateJan 2, 2002

Nature's own medicine for vision loss: Inhibitor of angiogenesis found by biologists at The Scripps Research Institute

Scientists at Scripps Research Institute have discovered a fragment of the human protein TrpRS that inhibits angiogenesis, offering new hope for treatments of age-related macular degeneration and diabetic retinopathy. The truncated form of TrpRS appears to be more potent than existing antiangiogenic compounds.

SourceScripps Research Institute·JournalProceedings of the National Academy of Sciences·DateJan 2, 2002

New UCLA imaging study first to show placebo alters brain function in individuals with major depression

A new UCLA imaging study has found that placebo alters brain function in individuals with major depression, showing increased activity in the prefrontal cortex for those who responded to treatment. This discovery challenges traditional views on treatment effectiveness and may lead to the development of new medications.

SourceUniversity of California - Los Angeles·JournalAmerican Journal of Psychiatry·DateJan 1, 2002

Other highlights in the Jan. 2 issue of JNCI

Researchers have identified matrix metalloproteinases as a key player in the spread of prostate cancer to the bone, offering a new target for treatment. Additionally, a genetic marker may be useful in predicting survival rates for patients with diffuse large B-cell lymphoma, while oral contraceptive use has been found to reduce ovarian...

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateJan 1, 2002

Progestin in oral contraceptives associated with lower risk of ovarian cancer

A new study analyzing oral contraceptive use among women with epithelial ovarian cancer found a significant association between progestin levels and reduced risk. Women using low-progestin/high-estrogen contraceptives were more likely to develop ovarian cancer compared to those using high-progestin/high-estrogen contraceptives.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateJan 1, 2002

Hormone progestin protects against ovarian cancer

A study led by Joellen Schildkraut at Duke University Medical Center found that oral contraceptives with higher levels of progestin may be more protective against ovarian cancer than those with lower progestin potency. Higher progestin levels were associated with a significant reduction in risk, even for short periods of use.

SourceDuke University Medical Center·JournalJNCI Journal of the National Cancer Institute·DateJan 1, 2002