Researchers at Nagoya City University develop a 10-amino acid sequence that enhances the cellular secretion of recombinant erythropoietin. The 'passport' sequence is recognized by a cargo receptor, allowing for improved production yields of biopharmaceuticals.
Researchers discovered that bacteria employ a strategy of adding new DNA while shedding unused genes, allowing them to avoid overloading their genomes. This process helps the bacteria outgrow competitors and potentially infect other organisms more easily.
A new IIASA study finds that many Europeans, especially women, underestimate their remaining life expectancy, leading to costly decisions. The researchers used SHARE data from 9 European countries to estimate subjective life expectancies from age 60 to 90 for men and women.
Dr. Susan Mohammed, a leading researcher on team mental model conceptualization and measurement, has been recognized as an SIOP Fellow for her significant impact on the field of industrial and organizational psychology. Her research on temporal cognition, diversity, and leadership has important implications for I-O psychology practice.
A renowned expert urges the establishment of an independent international safeguarding agency to handle athlete disclosures, investigate and process allegations, and support victims of abuse. An international offender database is also needed to prevent 'perpetrator migration' to new sport organisations.
Tropical Cyclone Herold intensified with a more defined eye in NASA satellite imagery, confirming a sharp intensification trend over the past 12 hours. The eye was visible down to the ocean's surface through clear clouds, revealing powerful bands of thunderstorms.
A study published in JPGN found that proton pump inhibitors (PPIs) may increase the risk of fractures in pediatric patients. The analysis showed a significantly higher fracture rate in children exposed to PPIs, with a 20% higher probability of fracture compared to non-exposed children.
Cancer cells rely on different factors for survival when DNA replication is blocked. Researchers found that inhibiting a key protein called Cdc7 selectively kills cancer cells by inactivating their safety mechanism. This discovery provides a new strategy for targeting cancer cells and developing anti-cancer agents.
Researchers at Swansea University have discovered that semiconductor materials can behave like metals and even superconductors when their surface crystals are structured in a specific way. This breakthrough could lead to advances in energy-efficient electronic devices with lossless energy transport.
Researchers have uncovered the intricate details of interleukin-2's interactions with receptor molecules, providing a blueprint for more targeted therapies. The study shows how IL-2 can act as either a throttle or a brake on the immune response in different contexts.
A new study reveals that dams in the upper Mekong River increase downstream nutrient bioavailability, contrary to the widespread assumption. The cascading effect of reservoirs increases hydraulic residence time and leads to a shift in phytoplankton species composition.
A large Kaiser Permanente study found that patients who underwent bariatric surgery maintained significantly more weight loss at 5 years compared to those who did not have surgery. Gastric bypass surgery showed better results than sleeve gastrectomy, with fewer participants regaining weight.
Researchers analyzed public genome sequence data to determine the origins of SARS-CoV-2. They found no evidence that the virus was engineered or created in a laboratory, supporting natural evolution as its origin.
A Rutgers-led study found that vitamin D levels greater than 12 nanograms per milliliter are associated with a higher rate of walking at 30 and 60 days after hip fracture surgery. Vitamin D deficiency is common in elderly patients with hip fractures, often occurring together with malnutrition.
Researchers discovered that plant circadian clocks play a critical role in water consumption, allowing plants to use resources more efficiently. The study found that altering circadian rhythms can improve water use efficiency without compromising plant growth.
The study found that farmers know less about pesticides applied to their seeds than those applied in other ways, due to seed treatments being exempt from labeling requirements. This lack of knowledge can lead to overuse of pesticides, harming the environment and farmers' health. The researchers recommend improved labelling of pesticide...
Researchers at Penn State developed a laboratory method to create membraneless compartments within a liquid, allowing them to segregate and concentrate components for important cellular functions. The findings could provide insight into how cells use these compartments to perform different tasks in different locations, with potential a...
Brian Welle named a Fellow of SIOP for his rigorous research and applications in improving workplace diversity, inclusion, and performance management. He has made significant contributions to the field through academic publications, research reports, and conference presentations.
Researchers at Stevens Institute of Technology developed an AI-powered smart insole that turns any shoe into a portable gait-analysis laboratory. The technology provides accurate real-time data on stride length, speed, and power, overcoming limitations of existing wearable technologies.
The study found SARS-CoV-2 stable in aerosols for up to three hours and on copper for up to four hours, while also detectable for 24 hours on cardboard and two to three days on plastic and stainless steel. This stability suggests people may acquire the virus through air and after touching contaminated objects.
Researchers from OIST create cheaper and user-friendly cryo-electron microscope to visualize biomolecules. The microscope uses low-energy electrons, which scatter more with lighter elements, providing a new way to image specimens.
Researchers at TUM designed an artificial binding protein with a unique chemical composition to bind to biological sugar structures. This protein has superior affinity to natural lectins and can inhibit cell growth, making it a potential therapeutic agent for conditions like cancer and infectious diseases.
Researchers in Japan have developed a low-noise fiber link to connect high-precision clocks, enabling the creation of powerful networks for applications like earthquake detection and communication systems. The system uses a cascaded link with ultralow-noise laser repeater stations to minimize noise and stabilize the laser signal.
Research finds that high levels of iron build-up in lung cells worsen asthma symptoms and lower lung function. The study suggests a link between iron absorption, immune system responses, and asthma severity.
Researchers analyzed the skull of 'Little Foot', a 3.67 million-year-old Australopithecus species, to understand its lifestyle. The study found that 'Little Foot' had head movements different from modern humans and could climb trees regularly.
Researchers at Baylor College of Medicine have identified a genetic signature combining certain maternal and fetal gene variants that are associated with a higher risk of preeclampsia. This genetic signature could be used to identify women at risk and prepare in advance to manage their condition.
John A. Weiner has been recognized as a leading expert in assessment tools and technology-based assessment solutions for employment and credentialing. His work on validity, fairness, and legal issues has had a significant impact on the field of industrial and organizational psychology.
Researchers have designed a system that uses tapered chains of spherical beads to effectively dampen high-frequency noises above human hearing range. The material's potential applications include use in headphones or other barriers to filter out such sounds, which may alleviate symptoms like nausea and headaches.
An international team of scientists used AI to predict disruptions in fusion reactions, avoiding energy release and damage to facilities. The algorithm was trained on thousands of experiments and successfully forecasted disruptions in real-time.
A UMass Amherst biostatistician has lent his expertise to the White House Coronavirus Task Force to estimate the median incubation period for COVID-19, which is just over five days. The task force has also received modeling data from leading researchers worldwide to inform mitigation measures.
The new journal 'Coronaviruses' will publish original research, letters, reviews, and case reports on all aspects of coronaviruses. It will be essential reading for virologists, epidemiologists, microbiologists, and healthcare workers interested in the latest information about coronaviridae.
A growing body of evidence suggests that antioxidant treatment in acute ischemic stroke may delay the onset of Alzheimer's dementia. Oxidative stress plays a major role in the pathogenesis of AD, and antioxidants have shown promise in animal models and some clinical trials.
Scientists from Boston University's Center for Systems Neuroscience found that scents trigger memories even years later and can reinvigorate forgotten details. The study suggests using odors as a therapeutic tool to treat PTSD and other mental health conditions.
A new genus of Cambrian sea worm, Utahscolex, has been discovered after a partial fossil specimen was unearthed in Utah in 1969. The discovery, led by Anna Whitaker, sheds light on the evolution of life on Earth and provides insights into the diversity of ancient marine life.
Scientists develop a simple method to modify graphitic carbon nitride, improving its catalytic and electrocatalytic performance. This advancement has potential applications in environmental pollution treatment and renewable energy production.
Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology discovered a way to inhibit side reactions in perovskite solutions, leading to improved stability, efficiency, and reproducibility of solar cells. A low-boiling-point stabilizer, triethyl borate, was found to be effective in stopping unwanted reactions.
Researchers mapped CB1R mRNA expression in male and female mice, revealing distinct patterns in brain regions associated with Parkinson's disease, maternal behaviors, and the estrus cycle. The study provides a foundation for understanding sex differences in physiological and pathological brain functions related to cannabinoids.
Emissions of CFC-11 and CFC-12 are larger than expected, with CFC banks slowly leaking these chemicals into the atmosphere, delaying ozone recovery and contributing to climate change.
Researchers at Boston Children's Hospital developed a new version of botox B with improved binding to nerves, leading to more effective paralysis, longer-lasting results, and reduced systemic toxicity. The enhanced toxin showed higher therapeutic efficacy and better safety range in a mouse model.
A single dose of THC can induce a range of psychiatric symptoms in healthy volunteers, including schizophrenia-like symptoms. No consistent evidence suggests that cannabidiol moderates the effects of THC.
A pediatrician used her clinical visits to educate families about the importance of completing the census. She aimed to minimize the negative effects of poverty and adversity on children by ensuring accurate data drives funding for critical resources like healthcare, schools, and nutrition programs.
Researchers found that increased lysosome numbers lead to hyperactivation of mTOR, stimulating abnormal cell growth. The study identified Rap1 as a regulator of lysosomal network organization and lysosome number, highlighting the central role of lysosomes in cancer progression.
Researchers have successfully developed a new, efficient method to create water-soluble fullerene compounds with high anti-HIV activity. This breakthrough could pave the way for new-generation drugs based on these compounds, offering hope for treating human immunodeficiency virus (HIV).
Dr. Shonna D. Waters has been named a Fellow of the Society for Industrial and Organizational Psychology (SIOP) for her significant impact on the field. She was granted Fellow status by the SIOP Executive Board, recognizing her outstanding contributions to industrial and organizational psychology.
The HD-MAP vaccine shows significantly enhanced immune responses compared to standard intramuscular injection, with faster onset kinetics and higher overall immune responses. The patch is stable for up to 12 months at temperatures as high as 40°C, providing potential for easy distribution without refrigeration.
Dr. Elizabeth L. Shoenfelt has made significant contributions to master's level I-O education and applied the science of I-O psychology to improve policies and processes in various fields. She is a renowned researcher with numerous publications and awards, including the SIOP Distinguished Teaching Contributions Award.
A new monograph published in PhytoKeys reveals details about the 425 New World species in the largest genus of morning glories, including six new species and nine new subspecies. The study found that most plants originated from two large centers: South America and the Caribbean Islands.
Researchers at Max Delbrück Center have identified protein EHD2 as a key regulator of fatty acid uptake in fat cells. The study found that people with normal weight produce more EHD2 than those who are overweight, suggesting a correlation between EHD2 levels and fat metabolism.
A new study suggests a nuclear conflict anywhere on Earth would lead to a decade of global cooling and a severe decline in crop production, compromising global food security. The study found that the sudden change in climate would cause significant crop losses, particularly in northern breadbasket regions.
A limited nuclear war could lead to severe losses in agricultural production and disrupt global trade, causing a food system shock unprecedented in documented history. The study found that major breadbasket regions would cut exports, leaving countries worldwide short of supplies.
Researchers at Princeton University have created a framework to understand and compare cities' food systems and their effects on climate change, water use, and land use. The study highlights the impacts of differences in meat consumption between Indian and U.S. cities, as well as differences in food processing.
Researchers have engineered silkworms to produce different variants of E-selectin, a critical adhesion molecule involved in inflammation, cancer, and disease processes. The study found that the connecting arm of E-selectin is crucial for binding, while longer armed proteins are better at tethering blood stem cells.
A new study published in The Lancet Public Health found that having gender-affirming documents improves mental health among transgender adults. The research, conducted by Drexel University researchers, analyzed data from 22,286 adults and found that those with their preferred name and gender on all identification documents were less li...
A study with 5,794 participants shows that starting veracity statements at the top does not increase honest reporting, contradicting earlier results. The findings challenge assumptions about the impact of statement order on self-reported honesty.
A study of over 20,000 American trans adults found that having access to identification documents reflecting their identified gender is associated with reduced psychological distress and lower rates of suicidal thoughts. The authors suggest policy changes to increase access to gender-concordant IDs, including reducing fees and administ...
A new framework understanding how light and noise pollution impacts wildlife has been developed by worldwide experts in ecology and physiology. Sensory danger zones have been identified as areas where sensory pollutants influence animal activity, posing a threat to imperiled species and urban wildlife.
A noblewoman from the Tang Dynasty was buried with her donkeys, indicating she wanted to continue playing her favorite sport, Lvju, after death. Researchers found donkey bones in Cui Shi's tomb, providing the first physical evidence of donkey polo in Imperial China.
A team of scientists has identified a triple-helix structure in calcium acetate hemihydrate, a compound formed on an ancient artwork through corrosion. The structure is similar to that found in collagen proteins and may have potential applications for bioinorganic chemistry.
Research reveals environmental reservoir dynamics play a crucial role in white nose syndrome's impact on bat populations. High levels of fungal pathogens in the environment lead to earlier, more severe infections and increased mortality in North America, whereas low levels result in delayed, less severe infections across Eurasia.
Researchers analyzed giant clam shell biogeochemical records from the South China Sea and found pulsed changes matched extreme weather events. The study suggests Tridacna shells could be used to record paleoweather patterns.