The NEC Society is working to improve understanding, diagnosis, prevention, and treatment of necrotizing enterocolitis (NEC), a leading cause of infant death. May 17 has been declared NEC Awareness Day in several states, aiming to generate more awareness and resources for a world without NEC.
Researchers created a virtual rodent with an artificial brain that can move like a real rodent, simulating complex behaviors using biomechanical data from real rats. The model uses deep reinforcement learning and AI to predict neural activity across behaviors.
A new chelator, L804, reduces off-target toxicity in PSMA radiopharmaceutical therapy by improving the bond between radioactive metal ions and targeting antibodies. This makes the therapy safer and more effective for patients.
Researchers found that expression of Gstt1 enables cancer cells to change their environment, allowing them to grow in new locations. The discovery could lead to new strategies for treating metastatic cancer, particularly pancreatic cancer.
Researchers have identified a distinct clinical pattern, PHES, that may respond better to targeted treatments in children with sepsis. This pattern is characterized by persistent hypoxemia, encephalopathy, and shock, and overlaps with biomarkers of inflammation and endothelial activity.
Researchers have discovered a better way to identify those at high risk of potential heart attacks and strokes by adding genetic information to health checks. The study found that combining clinical risk scores with polygenic risk scores significantly improves identification rates, especially among younger people.
Researchers compiled over 100 investigators' data from more than two dozen countries, increasing human spaceflight data by 10-fold. The results revealed longer-lasting molecular and physiologic changes distinct between crew members, targeting new areas for aerospace medicine.
Researchers discovered that Streptomyces davawensis produces virus-like particles facilitating host reproduction. The particles contain an enzyme degrading genomic DNA, allowing for extracellular DNA release and scaffold creation. This finding reveals the exploitation mechanism of virus-related nanoparticles for bacterial proliferation.
Researchers discover that epigenetic marks, particularly H3K27ac, are crucial for instructing genes to express themselves and generate folds. The Cux2 protein is found to be a master factor that utilizes the epigenetic landscape to regulate gene expression, leading to the formation of folds in the cerebral cortex.
A study by the University of Toronto found that 43% of Canadians with a history of bipolar disorder were symptom-free and 23.5% had achieved complete mental health. Factors contributing to psychological flourishing included having a trusted confidant, using spirituality as coping mechanisms, and absence of disabling chronic pain.
A new study analyzing historical data on biodiversity and climate for North America reveals a significant negative impact of climate change on birds. Specialist and migratory species are particularly at risk, with projected declines ranging from 2-16% by century's end due to habitat loss, pollution, and changes in food supply.
Researchers found that advertising on misinformation websites is pervasive among companies across several industries and amplifies the financing of misinformation. Consumers also face substantial backlash when ads appear on such websites, switching away from companies whose products are advertised on misinformation outlets.
Researchers at the Complexity Science Hub analyzed friendships and listening habits to find social networks are a crucial predictor of song popularity. The study showed that individuals with strong influence and large friend circles accelerate a song's popularity, making social connections a key factor in music trends.
Scientists at Hokkaido University have created a new technique for building nanoparticles using enzymes, enabling the production of various nanomaterials with controlled size and properties. This method has potential applications in technology, medicine, and quantum computing.
A new study published in the Journal of Clinical Oncology finds that open radical hysterectomy leads to better survival and lower recurrence rates for early-stage cervical cancer patients. The research, led by Houston Methodist researchers, builds on earlier findings that suggested minimally invasive surgery carries a higher risk of di...
Researchers at Princeton University have developed a new cement composite that mimics the strength and flexibility of seashells, increasing crack resistance and ductility. The composite, inspired by nacre's microstructure, exhibits improved fracture toughness and deformability, making it potentially tougher, safer, and more durable.
Researchers at WVU are exploring the potential of solar panels to generate energy on grazing lands, diversifying farmers' income streams and promoting more sustainable practices. The study aims to understand how dual-use solar systems impact soil health and animal performance.
Researchers found low alignment between hospitals and health departments, particularly concerning social determinants of health, despite both entities having formal responsibilities to their communities. The top identified health needs included mental health, substance use, and obesity.
A new Pt-Co@NCS catalyst achieves exceptional performance in alkaline hydrogen evolution reaction, overcoming slow water dissociation. The unique porous structure and nitrogen-rich surface enhance hydrophilicity and catalytic interaction, promoting efficient water dissociation.
Coptis teeta Wall. has been traditionally used to treat malaria, stomach ache, diarrhea, skin conditions, eye disorders, and gastrointestinal issues. The plant's compounds have shown antibacterial activity, anti-inflammatory effects, and potential in treating chronic conditions like diabetes and cancer.
The IOF position paper emphasizes the need for population-specific vitamin D approaches, considering factors like diet, skin pigmentation, and supplement use. The authors also highlight the importance of standardized measures of 25(OH)D in future studies.
A new study by University of East Anglia and Ocean University of China found that ocean algae play a significant role in producing DMSP, a compound that helps regulate the Earth's climate. The discovery could change our understanding of how these tiny marine organisms impact the planet.
Researchers at Beijing University of Chemical Technology and BOE Technology Group Co., Ltd. have developed a novel transparent organic-inorganic hybrid photoresist with a highly tunable refractive index of up to 2.0, allowing for precision machining of optical microstructures and improving display device efficiency. The material exhibi...
Research from the University of South Australia found that people with knee OA unconsciously believe exercise is dangerous, despite medical advice. The study developed a tool to detect and evaluate these implicit beliefs, suggesting they can be a better predictor of actual behavior than reported attitudes.
Researchers have developed a novel approach to treat colorectal cancer using simultaneous delivery of alpha- and beta-radionuclides, significantly reducing side effects. The therapy, known as pretargeted dual-isotope radionuclide therapy, has been shown to be effective in inducing tumor shrinkage and cures.
A satellite galaxy of the Milky Way, Crater 2, has been studied by a UC Riverside-led team. They offer an explanation for its unusual properties using the self-interacting dark matter (SIDM) theory.
A study by University of Washington School of Medicine found that a cognitive test is an inaccurate predictor of athletes' concussions. Instead, symptom reports were the most accurate indicator of concussion. The study involved 92 NCAA Division I athletes who sustained a concussion and their teammates as matched control subjects.
A comprehensive study by researchers at the University of Córdoba found that teachers' commitment to inclusive education positively impacts students' socio-emotional skills. The study, involving over 3,500 students and 294 teachers, reveals the decisive role of teachers in boosting social-emotional skills through inclusive education.
Researchers at NC State University have developed a technique to create miniature soft hydraulic actuators that can move small soft robots, allowing for exceptional control and delicacy. The actuators use shape memory polymers and microfluidic channels to control the motion and shape change of the soft robots.
Researchers discovered wind from a black hole's radiation blasting gas out of its galaxy at an unprecedented speed. The study sheds light on how active black holes shape their galaxies by spurting on or snuffing out new star formation.
A new WhatsApp-based program has shown significant improvements in treating depression among older adults in Brazil. The Viva Vida program used simple audio messages and images to provide education on depression and behavioral activation, with a 10-point improvement in symptom reduction between intervention and control groups.
Researchers found that nocturnal bull ants can detect exceedingly low levels of polarised moonlight produced throughout the lunar month to navigate during the night. The ants altered their direction in response to changing rotations of overhead lunar light polarisation, suggesting a stable cue across the lunar cycle.
This study introduces modern innovations in Chinese aquaculture, focusing on genetic breeding, fertility biotechnology, polyculture, eco-agriculture, smart aquaculture, and eco-engineered aquaculture. The research proposes ten paradigm changes to promote sustainable aquaculture development and global food security.
Researchers have developed a method to create and control optical qubits in silicon with high precision, enabling the fabrication of reliable quantum computers. This breakthrough could advance quantum computing and networking capabilities, paving the way for breakthroughs in human health, drug discovery, and artificial intelligence.
Generative AI has both positive and negative effects on social equality, impacting work, education, healthcare, information, and misinformation. Policymakers are urged to implement policies such as tax code changes, data unions, and anti-misinformation campaigns to ensure the technology is used to increase equality
A new study reveals significant declines in atmospheric levels of potent ozone-depleting substances and harmful greenhouse gases, confirming the success of the Montreal Protocol. The findings show a notable reduction in HCFCs, which are also contributing to global warming.
Research by Osaka Metropolitan University suggests that converting vacant homes in old new towns into healthcare facilities can slow population decline. This urban transformation can enable older adults to remain in their communities, promoting healthy and connected living.
Patient harms associated with medical procedures and treatment increased globally from 11 million to 18 million between 1990 and 2019. Older people, especially those aged 65-69, were disproportionately affected by these incidents.
Scientists studied how microgravity impacts human peripheral blood mononuclear cells and identified potential compounds to counter its effects, including the antioxidant quercetin. The findings have implications for immune aging on Earth and provide a resource for developing countermeasures.
Dr. Jeetain Mittal's NIH grant will support multiscale computational models investigating phase separation in biology, particularly heterochromatin formation and its role in neurodegenerative diseases. The research aims to elucidate the molecular origins of phase separation using innovative models and methods.
A study in São Paulo state found that chikungunya virus circulated silently for years before causing major epidemics. The researchers monitored residents for four years and discovered a significant rise in seroprevalence from 0.35% to 2.3%. This finding underscores the need for strengthened disease surveillance.
A new study published in JAMA Network Open found that depressive symptoms are linked to subsequent memory decline in older people, and conversely, poorer memory is associated with an increase in depressive symptoms. The researchers suggest that addressing depressive symptoms may help slow down memory decline.
A University of Adelaide research team used a new method to date garnet grains in South Australian pink sand, revealing they are around 590 million years old. This age does not match local geological events, suggesting the garnet originated from an unknown ancient Antarctic mountain belt beneath the ice sheet.
A study by the University of Adelaide found that individuals tend to spend more when using cashless payment methods compared to cash. The 'cashless effect' was stronger for purchases of luxury items like jewelry.
A study using induced pluripotent stem cells has revealed that inflammation triggered by retrotransposons and interferon signaling causes atherosclerosis in Werner syndrome patients. The researchers propose targeting the interferon signaling pathway as a potential treatment for reducing stroke and heart attacks.
New Alzheimer's drugs aim to halt condition progression, but UK patients may face limited eligibility due to lack of biomarker testing and diagnostic scans. The study suggests that over 20,000 people per year will need access to confirmatory investigations to determine suitability for treatment.
Nitrous-oxide emissions have increased by 40% over the past four decades, resulting in accelerating atmospheric accumulation of this potent greenhouse gas. Agricultural production is the largest source of emissions, and improving practices can help reduce nitrous-oxide emissions and water pollution.
Researchers have developed a novel CMUT-based biosensor that can detect single-stranded DNA oligonucleotides with high specificity without needing external labels. The biosensor features improved selectivity and label-free detection, making it suitable for point-of-care diagnostics.
Zhen Yan and his team found thousands of molecular alterations in bodies after various durations of endurance exercise training, which have implications for human health. The study revealed that exercise can be a potent protection against diseases such as nonalcoholic fatty liver disease and inflammatory bowel disease.
The American College of Allergy, Asthma & Immunology (ACAAI) has issued a position paper on the safety of administering live vaccines to patients treated with dupilumab. The review suggests that treatment should not be stopped, but rather, shared decision-making between doctors and patients is recommended to weigh risks and benefits.
The fungus secretes enzymes that transform tea chemical components through oxidation, degradation, and condensation reactions. This results in high-quality fermented teas with enhanced flavor and health benefits.
Research at the University of Zurich reveals that the first week after birth is a critical period for the development of senses, particularly smell and touch. Olfactory stimuli can induce neural activity across multiple brain regions, including areas responsible for non-olfactory sensory processing.
A new study found that adolescents with higher rates of prediabetes often experience adverse social determinants of health, such as food insecurity and low household income. Screening for these non-medical factors may help identify youth at risk of progressing to type 2 diabetes.
Researchers discovered that Klebsiella oxytoca bacteria compete with salmonella for nutrients, employing multiple strategies to combat the spread of the infection. The bacteria also produce a toxin that has anti-salmonella effects, which may be harnessed to develop new treatments.
The ELITE satellite, scheduled for completion by 2025, will validate new satellite technologies and study unique conditions of Very Low Earth Orbit (VLEO) and the Earth's surface. The satellite is equipped with a special electric propulsion system and will operate in VLEO, a relatively unexplored region of space.
Researchers at Clemson University have developed a new noncentrosymmetric triangular-lattice magnet, CaMnTeO6, which displays strong quantum fluctuations and nonlinear optical responses. This breakthrough material has the potential to lead to advancements in solid-state quantum computing, spin-based electronics, resilient climate chang...
Research shows people with obesity are more sensitive to price when buying unhealthy foods, while those with normal weight are not. A 10% price hike on these categories can lead to a significant reduction in consumption, such as decreased frozen pizza purchases.
Scientists at Virginia Tech have discovered that controlling the precise timing of electrical pulses can rebalance synaptic connections between nerve cells, selectively up- or down-regulating those connections. This finding suggests potential avenues for more effective treatment strategies for mild traumatic brain injuries.
The new MEMS Huygens clock offers improved precision and stability, with Allan deviation improving by a factor of 3.73 at 1 second and 1.6343 × 10^5 times at 6000 seconds.
A new study assesses the impact of freeze-thaw cycles on concrete structures in China's plateau region. The researchers introduce a spatiotemporal distribution model to analyze F–T action levels and create a nationwide zonation for improved infrastructure durability.