Research reveals that even short exposure to loud noise during Stanley Cup games can be harmful, with fans receiving up to 81% of their daily noise dose without ear protection. Earplugs can mitigate this risk and help prevent hearing loss and tinnitus.
Researchers have identified unique expression domains for two proteins, SPLUNC1 and SPLUNC2, in the lungs of people with cystic fibrosis. The discovery could help understand the immune system's role in the disease and potentially prevent lung damage.
A recent U of M study found that treating periodontal disease in pregnant women does not reduce the risk of preterm birth or low birth weight. The study, published in the New England Journal of Medicine, concluded that while treatment is safe and effective, it does not directly affect a woman's risk for these complications.
Researchers at OHSU School of Dentistry identify interaction between two proteins in nerve cells carrying pain information from the head and neck to the brain. This finding may help develop therapies for migraines and other craniofacial pain conditions.
Researchers at the University of Iowa identified a crucial role for IRF6 gene in skin development, which may lead to new treatments for cleft lip and palate. The study found that IRF6 regulates keratinocyte proliferation and differentiation, shedding light on this critical cell type.
The UCSF Institute will support innovative approaches in translational and clinical science across four schools, with a focus on accelerating the pace of scientific discovery into patient care. The institute's goal is to find more efficient ways to move basic research findings into the clinic.
A study published in BMC Health Services Research reveals ethnic disparities in preventive screening procedures are larger when estimated using Medicare claims, with the exception of PSA testing. Despite adjusting for various factors, minorities tend to report higher rates of receiving preventive procedures without a submitted claim.
The Edmonton Protocol clinical trial demonstrates islet transplantation as a promising procedure for managing severe Type 1 Diabetes, achieving insulin independence in 44% of recipients and improved blood sugar control. However, long-term sustainability varies, highlighting the need for continued research into this therapy.
Teenagers who drink alcohol are more likely to be victims of violence, a Cardiff University study has found. The research, which surveyed over 4,000 children aged 11-16 in England, showed that drinking habits can increase the risk of injury.
Researchers found a positive association between periodontal disease and coronary heart disease, particularly in individuals under 60 with significant alveolar bone loss. The study suggests that chronic infections and inflammatory responses from periodontal disease may contribute to the development of atherosclerosis.
Researchers found that high salivary melatonin levels may be associated with lower periodontal disease severity, as measured by the community periodontal index score. This suggests that melatonin's antioxidant properties may help protect against inflammation and oxidative damage in the oral cavity.
A six-year study found high progression rates of diabetic retinopathy in African Americans with type 1 diabetes, linked to poor glycemic control and high blood pressure. The study highlights the need for improved medical care and regular eye exams to detect vision-threatening diabetic retinopathy.
A new screening program using digital cameras and the Internet effectively identifies early childhood dental caries (ECC) in 40% of toddlers. The program, developed by University of Rochester Medical Center researchers, uses photos taken by child care center health assistants to detect ECC before it becomes a painful problem.
A new study published in the Journal of Periodontology found that combining tongue and tooth brushing with dental flossing significantly decreased gingival bleeding by 38 percent after a two-week oral hygiene program. Halitosis was also reduced, with gingival bleeding sites increasing by almost four percent in those who didn't floss.
A new tooth whitening procedure developed by Dr. Kim L. Capehart has been found to significantly lighten stubborn tetracycline stains, saving patients over $10,000 in dental restorative fees. The treatment involves a combination of prescription fluoride toothpaste, UV light, and customized trays.
Researchers used gene therapy to eliminate disabling muscle contractions in a mouse model of the most common form of adult-onset muscular dystrophy. The approach corrected myotonia, or muscle hyperexcitability, and eliminated muscle contractions as early as four weeks after injection.
Researchers have found that protein-coated dental implants can induce bone formation and promote tissue regeneration. In laboratory tests, the protein-induced bone growth nearly completely regenerates lost tissue around teeth.
Researchers found that AAS abusers had statistically significant levels of gingival enlargement compared to non-users, requiring a gingivectomy for many cases. Gingival inflammation was also higher in the user group, suggesting potential long-term effects on periodontal health.
Researchers present Phase 2 clinical results showing AC-100 stimulates the formation of new dentin, especially in deepest cavities. The study demonstrates a novel biological approach to promoting dentin formation as a supplement to routine dental care.
Scientists at Rutgers have created a computerized model to understand the degree of harmful exposure in the immediate aftermath of the World Trade Center attacks. The model, combining satellite data and regional weather forecasts, provides a way to evaluate human exposure to aerosols released during the disaster.
Dr. Polverini, a renowned expert in oral pathology, has received the prestigious IADR Oral Medicine and Pathology Research Award for his groundbreaking work on angiogenesis and oral cancer. The award is supported by Sunstar Butler and recognizes his contributions to the field.
Dr. Ferracane is recognized for his pioneering work on dental composites, behavior of mercury in amalgam, and Fourier transform infrared techniques. He is also an esteemed teacher and has made significant contributions to the dental materials community through his research, teaching, and service.
Dr. Meechan has received the IADR Pharmacology, Therapeutics, & Toxicology Research Award for his contributions to dental care management and medically compromised patients. The award recognizes his research interests in local anesthesia and pain control.
Researchers found that cranberry flavonoids can inhibit the formation of dental plaque polysaccharide matrix, block bacteria adherence, prevent acid formation, and reduce acid tolerance of cariogenic organisms. These compounds may serve as potential anti-caries/anti-plaque agents.
Dr. Feine has made significant contributions to prosthodontics through her research on implant-supported prostheses and maxillary implant prostheses on speech. She is recognized for her outstanding research accomplishments in the field of prosthodontics with the Research in Prosthodontics and Implants Award.
The IADR has reinstated the Isaac Schour Memorial Award, a prestigious award that recognizes outstanding scientific contributions in anatomic sciences. The award will be funded at the same level as other IADR Distinguished Scientist Awards and will consist of a $2,000 prize and a plaque.
A study by the American Academy of Periodontology reveals that chronic stress, depression, and elevated cortisol levels are potential risk indicators for periodontal disease in adults aged 50 and older. Short-term psychological stress was linked to elevated plaque levels, while long-term physical stress was associated with gingivitis.
A new type of medication, varenicline, is being developed to target the neurobiological mechanism of nicotine dependence. Trials have shown promising results, with short-term and long-term quit rates significantly higher than those achieved with existing medications or placebos.
Research suggests that pregnant women with periodontitis have higher CRP levels, which may contribute to preeclampsia and preterm delivery. The study's findings support previous research linking periodontal disease and inflammation with adverse pregnancy outcomes.
A case report identified a serious oral post-surgical complication in a patient receiving IV bisphosphonates for breast carcinoma-related osteopenia. The patient developed osteonecrosis following periodontal surgical therapy, emphasizing the importance of dental evaluations before initiating IV bisphosphonate therapy.
A recent study found that only 11% of seniors in Western New York have dental insurance, with financial need being a major barrier to receiving dental care. The study also showed significant disparities in access to dental care between urban and rural areas.
A UK study found that saliva can be tested for signs of periodontal disease, a condition characterized by persistent inflammation and tissue breakdown. The research team identified biomarkers in saliva that could aid in diagnosing and monitoring the disease.
A study found rodeo athletes recover from whiplash injuries faster and report fewer symptoms compared to spectators, suggesting a different attitude toward injury. The team plans to investigate why rodeo athletes can continue working despite being trampled by bulls.
Children born preterm show cognitive and motor deficits, while early social environment plays a significant role in development. fMRI scans reveal distinct brain activation patterns related to medical and environmental risks.
A recent study found that insulin levels increase in African American children during puberty, making them more susceptible to Type 2 diabetes. The study, which tracked participants over seven years, also revealed that pancreatic beta-cell function decreases in African American youth, further exacerbating the risk.
Scientists have developed a standardized saliva RNA test for oral cancer detection, showing high accuracy rates in detecting oral cancer. The test has been confirmed to be highly accurate in identifying four saliva oral cancer RNA biomarkers, reducing mortality and morbidity for oral cancer patients.
A recent study by Case Western Reserve University found that private practice dentists and hygienists primarily counsel middle-class patients with higher education on preventing dental diseases. Despite the lack of peer feedback, most dentists use comfort-giving strategies to make patients feel at ease during visits.
Researchers seek to confirm that deep brain stimulation can help patients with severe obsessive-compulsive disorder (OCD) and understand the disrupted brain network. A clinical study will examine the effects of DBS at different sites and assess treatment effectiveness.
Researchers are developing nanotechnology approaches for oral health diagnosis and treatment, including precise drug delivery using dendrimers and PEBBLES-probes. These systems aim to increase the effectiveness of anti-cancer drugs and control mineral composition in bone tissue.
Chronic periodontitis and certain bacteria are linked to preeclampsia in pregnant women. Periodontal infection may increase the risk of preterm birth due to its association with cardiovascular disease. The study's findings suggest that pregnancy-associated gingivitis is preventable and easy to treat.
A study by University of Alberta researchers found that fine particulate matter from pollution causes cardiovascular problems in rats with obesity and insulin resistance. The findings suggest a significant public health risk for vulnerable populations, particularly those living near areas burning coal or diesel exhaust.
A randomized study found that fluoride varnish significantly reduced tooth decay risk in young children, with no adverse events reported. The study's results support the use of fluoride varnish to prevent tooth decay in very young children and highlight the importance of early dental visits.
Researchers have identified compounds in licorice root that could potentially combat tooth decay. Further studies are needed to confirm the effectiveness of these compounds as cavity-fighting agents, but they show promise for use in mouthwash or toothpaste.
Low-income and education levels linked to higher prevalence of severe periodontitis among African Americans. Socioeconomic status is a significant factor in periodontal health, independent of neighborhood conditions.
The Journal of Endodontics, a peer-reviewed journal publishing scientific articles and case reports on pulp conservation and endodontic treatment, has been published by Elsevier since January 2006. The partnership aims to strengthen the journal's position as a vital resource for the worldwide dental community.
Researchers at Virginia Tech have developed a new bone tissue engineering material using amorphous calcium phosphates, which they believe could lead to faster and higher quality bone formation. The team's work, in collaboration with the American Dental Association, is currently in press for several scientific journals.
Long-term antibiotic medication does not prevent recurrent myocardial infarcts in patients without periodontitis. Patients with periodontitis are more likely to experience cardiovascular events, especially under the age of 65.
Researchers have identified a genetic factor leading to forehead and frontal bone malformations, which can cause severe craniofacial defects. A potential therapy using FGF supplements may help prevent these defects in embryos with missing TGF-beta genes.
Researchers at Oregon Health & Science University (OHSU) have identified a critical gene, Brg-1, that regulates the differentiation of stem cells into neurons and glial cells in the brain. This discovery could lead to new therapies for brain injuries, Parkinson's disease, and other conditions affecting brain function.
Harvard researcher Martin Nweeia discovers that the narwhal's tooth has hydrodynamic sensor capabilities, allowing it to detect salinity and particle gradients in Arctic waters. This unique adaptation enables the whales to survive in their icy environment and potentially discern prey.
Scientists have discovered that Streptococcus mutans, a decay-causing organism, can survive without the SRP pathway. The bacteria altered to lack SRP components were able to adapt and survive gradual increases in acid resulting from their own metabolism.
New Jersey Institute of Technology researchers are developing technologies to assist children with cerebral palsy, including a robotic arm that guides human motion and interactive video games to promote motor skill improvement. The goal is to enhance the children's quality of life by reducing stiffness in their joints.
The National Institutes of Health (NIH) has joined forces with advocacy groups to fund research on autism susceptibility genes. The initiative aims to expand knowledge of the genetic factors involved in autism and develop targeted therapies.
The NIH will provide nearly $10 million in funding for nine Science Education Partnership Awards, supporting programs that increase science literacy among K-12 students and teachers from underserved populations. These awards aim to make science more accessible and encourage young people to pursue careers in science.
Researchers at Rutgers University have made new findings linking genetic variants to susceptibility to autism and schizophrenia. The study suggests that a mutated form of the EN2 gene may contribute to up to 40% of autism cases, while another gene called CAPON has been implicated in schizophrenia.
The university will use the grant to enhance its Clinical Scholars Program, which supports young investigators in a three-year educational and training program. The initiative aims to create an environment for career development of young faculty in clinical research.
The National Children's Study will follow over 100,000 children from birth to age 21 to examine the impact of environmental factors on child health. The study aims to improve the lives of children in Queens and inform child health guidance and policy nationwide.
A significant proportion of young adult patients examined had well-established periodontal disease despite no signs or symptoms. Women affected by this disease faced a higher risk of preterm birth and other pregnancy complications, corresponding to systemic inflammation indicators.
A report on vaccine markets is criticized for favoring large firms and delaying access to effective vaccines. The author recommends using advanced purchase commitments as a complement to research funding.
A recent study published by the American Gastroenterological Association found that nearly 80% of Asian patients with chronic HCV developed cirrhosis after 60 years of infection. The study's results confirm that fibrosis progression is the same across ethnic groups, leading to cirrhosis and liver disease at a similar rate in everyone.