Add BrightSurf on Google Email

Search results for “Chemical Pathology”

1,000+ results for "Chemical Pathology"

Minimally invasive solid tumor biopsy may replace surgery to get diagnostic specimens

A minimally invasive core-needle biopsy guided by CT scans or ultrasound appears to be an effective way to obtain tumor samples, replacing surgery. The technique shows high accuracy rates for diagnosing childhood cancers, with a sensitivity of 97% and specificity of 100%, according to St. Jude Children's Research Hospital researchers.

Pinpointing a culprit molecule in Alzheimer's disease

Researchers created transgenic mice overproducing Ab40 and Ab42 to study their roles in AD pathology. The results showed that Ab42 mice accumulated extensive amyloid plaque and neural damage, while Ab40 mice showed little disease pathology. The study provides evidence for the critical role of Ab42 in initiating amyloid deposition.

SourceCell Press·JournalNeuron·DateJul 20, 2005

New insight into Huntington's disease pathology

Studies in mice with genetically engineered mutant huntingtin protein found that widespread production led to locomotor problems, neurodegeneration, and abnormal brain connections. Conversely, restricted production showed little difference from normal mice, suggesting cellular interactions play a significant role in HD pathogenesis.

SourceCell Press·JournalNeuron·DateMay 4, 2005

Alternate view for pathology of AD

A team of researchers from Case Western Reserve University propose an alternate view on the pathology of Alzheimer's disease (AD), suggesting that neurofibrillary tangles (NFTs) may be protective against oxidative stress. NFT-bearing neurons can survive for decades, and their presence may be a response to reduce oxidative damage.

SourceCase Western Reserve University·JournalTrends in Molecular Medicine·DateApr 18, 2005

Nanoscale chemical sensors

Researchers have discovered that nanowires composed of lithium, molybdenum and selenium atoms can detect significant changes in electrical resistance when exposed to vapors of organic solvents. This property enables the creation of simple chemical sensors that can measure the acidity of a solution.

Immune therapy 'untangles' Alzheimer's disease

Researchers found that immune therapy against Alzheimer's disease not only removes the toxic amyloid plaque but also clears protein tangles, suggesting a broad assault on the disease. The treatment was shown to clear both hallmark lesions of AD by alleviating interference in the cell's protein garbage disposal system.

SourceCell Press·JournalNeuron·DateAug 4, 2004

Scientists find gene that protects against potato blight

Researchers at the University of Wisconsin-Madison have identified a gene that protects potatoes from late blight, a fungal pathogen responsible for the Irish potato famine. The discovery holds significant potential to save farmers hundreds of millions of dollars and benefit the environment by reducing toxic chemical applications.

SourceUniversity of Wisconsin-Madison·JournalProceedings of the National Academy of Sciences·DateJul 14, 2003

Study shows molecular analysis of early breast cancer lesions may be key to choosing best treatment

Researchers developed new methods for diagnosing breast cancer based on gene expression signatures, correlating with traditional pathological classifications. The study found that early-stage lesions contain molecular signatures reflecting tumor aggressiveness, potentially changing the course of cancer progression.

SourceMassachusetts General Hospital·JournalProceedings of the National Academy of Sciences·DateMay 12, 2003

UCR scientists modify existing chemical scrubber to environmentally friendly, all-natural filter

Scientists at UC Riverside have modified an existing full-scale chemical scrubber to a biological trickling filter, achieving treatment rates comparable to chemical scrubbers. The conversion resulted in annual savings of $30,000 per year, with potential for widespread adoption and significant cost benefits.

SourceUniversity of California - Riverside·JournalProceedings of the National Academy of Sciences·DateMay 7, 2003

Abnormal chemical bonds cause bleeding disorder

Researchers at Washington University School of Medicine have found that a defective form of vWF causes chemical bonds to persist longer than they should, leading to a bleeding disorder. The defect in the vWF protein changes the kinetics of the chemical bonds between the protein and platelets, resulting in the disease.

SourceWashU Medicine·JournalBiophysical Journal·DateJun 24, 2002