The American Chemical Society's annual employment survey reveals that median salaries for US chemists have increased by 4-5% across all levels. Notably, there has been a dramatic shift towards biologically-related jobs among chemists over the past two decades.
Researchers found that women have more global AD pathology due to neurofibrillary tangles and experience clinical symptoms of AD nearly 20 times more often than men. This suggests that Alzheimer's disease is stronger in women, potentially linked to estrogen deficiency or other protective factors.
A minimally invasive core-needle biopsy guided by CT scans or ultrasound appears to be an effective way to obtain tumor samples, replacing surgery. The technique shows high accuracy rates for diagnosing childhood cancers, with a sensitivity of 97% and specificity of 100%, according to St. Jude Children's Research Hospital researchers.
Researchers created transgenic mice overproducing Ab40 and Ab42 to study their roles in AD pathology. The results showed that Ab42 mice accumulated extensive amyloid plaque and neural damage, while Ab40 mice showed little disease pathology. The study provides evidence for the critical role of Ab42 in initiating amyloid deposition.
A new XML-based architecture could improve access to chemical information in biomedical literature, reducing errors and increasing publication efficiency. The proposed system would link to open databases like PubChem, enabling readers to easily identify compounds mentioned in articles.
The American Chemical Society reports that chemical production and earnings have increased, while employment numbers have declined. This trend is based on the ACS's annual Facts & Figures tables, which provide detailed statistics on the US chemical industry.
A recent study found that living near a casino increases the risk of problem gambling, with a 90% increase in odds for those within 10 miles. Social and environmental influences also play a role, with respondents from disadvantaged neighborhoods reporting higher rates of problem gambling.
The top chemical producers saw a significant increase in sales in 2004, with Dow Chemical leading the way at $40 billion. DuPont's sales remained relatively stable, while ExxonMobil Chemical experienced a notable jump of 38%.
Studies in mice with genetically engineered mutant huntingtin protein found that widespread production led to locomotor problems, neurodegeneration, and abnormal brain connections. Conversely, restricted production showed little difference from normal mice, suggesting cellular interactions play a significant role in HD pathogenesis.
A new study found that exercise can delay the development of Alzheimer's-like brain changes in mice by decreasing beta-amyloid levels. Exercise was shown to improve learning and memory in mice with AD-like pathology, suggesting a potential mechanism for reducing cognitive decline.
A new sensor system combining flame photometer, ion mobility spectrometer and surface acoustic wave array detects chemical vapors with high accuracy. The PSU-developed CINET software reduces false alarms by correlating data from multiple detectors.
A team of researchers from Case Western Reserve University propose an alternate view on the pathology of Alzheimer's disease (AD), suggesting that neurofibrillary tangles (NFTs) may be protective against oxidative stress. NFT-bearing neurons can survive for decades, and their presence may be a response to reduce oxidative damage.
A software suite will be developed to simulate and calculate chemical properties, enabling the control of complex chemical processes in Navy's all-electric ships. The partnership combines advances in molecular theories, computer algorithms, and supercomputing capabilities.
Cancer cells' DNA is tightly compacted, making it resistant to enzyme digestion, unlike healthy tissue. The study's findings suggest new diagnostic and therapeutic tools for distinguishing different types of tumors.
Professor Johnson is awarded the IADR Oral Medicine and Pathology Research Award for his significant contributions to dental caries, periodontal diseases, and oral cancer research. He has also made a notable impact on oral cancer prevention through his advocacy.
A study of 180 Catholic nuns and priests found that nearly half with mild cognitive impairment met pathologic criteria for Alzheimer's disease. Meanwhile, about a quarter had cerebral infarcts, indicating a possible 'reserve' capacity in the brain that prevents cognitive decline despite pathology.
A new study finds that MRI is more accurate than current standards in assessing the effectiveness of neoadjuvant chemotherapy for breast cancer. The imaging technique correctly identified the presence of residual tumor in 71% of cases, while sonography and clinical examination were less accurate.
The US chemical industry saw significant earnings growth in Q4 2004, with total earnings rising 52% year-over-year to $9.58 billion. Sales increased 15.1% to $139.7 billion, driving aggregate profitability to 6.9%. Rising selling prices and strong demand fundamentals contributed to the growth.
The INEEL-designed Munitions Assessment System processes drums containing multiple chemical munitions, using digital radiography and computed tomography to identify chemical fill. The system also includes portable isotopic neutron spectroscopy for accurate chemical analysis.
In a breakthrough discovery, Stanford researchers have found that mast cells can provide protection from sepsis by destroying a molecule that contributes to the pathology and death associated with this bacterial infection. The study reveals a new role for mast cells in limiting damage caused by endothelin-1.
Chronic exposure to pesticides like rotenone has been linked to Parkinson's disease pathology in monkeys. Exercise has shown potential in protecting against dopamine neuron loss and slowing disease progression in rats. Rotigotine, a new drug, may also offer neuroprotective properties.
Researchers at Temple University's Sbarro Institute developed a new blood test that uses CDK9/CYCLIN T1 expression to accurately diagnose lymphoma cancer types and stages. The study, published in the Journal of Pathology, found that analyzing these molecules in a blood sample can pinpoint the presence of lymphoma with high accuracy.
Researchers have discovered that nanowires composed of lithium, molybdenum and selenium atoms can detect significant changes in electrical resistance when exposed to vapors of organic solvents. This property enables the creation of simple chemical sensors that can measure the acidity of a solution.
The American Chemical Society has recognized four companies for developing innovative therapies for various ailments, including eye disease and high cholesterol. These breakthroughs were made possible by the work of industrial chemists and chemical engineers who have led to commercially successful products that improve quality of life.
Researchers found that immune therapy against Alzheimer's disease not only removes the toxic amyloid plaque but also clears protein tangles, suggesting a broad assault on the disease. The treatment was shown to clear both hallmark lesions of AD by alleviating interference in the cell's protein garbage disposal system.
Demand for US chemical products increased while firms cut costs. Dow Chemical topped sales at $9.3 billion, followed by DuPont at $8 billion. DuPont led earnings with $964 million, ahead of Dow's $469 million increase in the same quarter last year.
A new tumor classification system combines molecular biology and classic pathology to provide a comprehensive and consistent way of typing tumors. The system uses both the type of cells that form a tumor and its molecular characteristics to determine its behavior, offering improved accuracy and insight into treatment options.
Dr. Gutkind received the IADR Oral Medicine/Pathology Research Award for his seminal research on normal and oncogenic functions of non-receptor protein-tyrosine kinases. He has published over 200 scientific papers and contributed to developing molecular markers of disease progression in oral malignancies.
Dr. Soskolne has made significant contributions to scientific literature in the fields of oral pathology, bone physiology, and the pathogenesis of periodontal diseases. He developed an organ-culture model for studying bone remodeling, which has been used extensively to study bone physiology.
The chemical capsaicin in peppers has been found to stimulate circulation, trigger pain relief, and even ease arthritis symptoms. It is also used in repellent sprays, marine coatings, and various drugs.
Researchers have created a new mouse model of Alzheimer's disease to study the effects of toxic protein p25 on brain degeneration. The model, developed by Harvard Medical School scientists, shows high levels of p25 accumulation leading to neuronal death and tau pathology after just 12 weeks.
Researchers found that Hedgehog's signal is required for cancer growth in the digestive tract. A plant-derived chemical called cyclopamine blocked this signal, killing tumors in mice without harm.
The Gerontological Society of America (GSA) has awarded the Geron Corporation - Samuel Goldstein Distinguished Publication Award to Dr. Ikeno for his outstanding research on the pathology of aging and the role of oxidative stress in age-related pathology. The award recognizes his contributions to the field of gerontology.
Rao's research aims to understand the mechanism of virus assembly, a crucial step in viral transmission and disease spread. By studying the brome mosaic virus, his lab hopes to develop new strategies for blocking virus assembly and preventing disease.
The Center for Environmental and Biological Chemistry (CEBC) will focus on developing greener chemical processes, including catalysts for cleaner solvents. Researchers will work with industry partners to create more efficient reactors and reduce waste, aiming to improve the quality of life through cleaner chemicals.
Researchers discover that the immune synapse theory suggests the synapse is linked to both activating and deactivating T cells, with its ability to amplify signals also shutting down messages in later stages. The findings confirm key concepts in the immune synapse theory.
Dr. Peter Ward, a renowned U-M pathologist, has received the American Thoracic Society's highest honor for his pioneering research on inflammation and lung biology. His work has significantly broadened the understanding of lung health and disease, influencing the career development of many clinicians and scientists worldwide.
Researchers at the University of Wisconsin-Madison have identified a gene that protects potatoes from late blight, a fungal pathogen responsible for the Irish potato famine. The discovery holds significant potential to save farmers hundreds of millions of dollars and benefit the environment by reducing toxic chemical applications.
Research suggests that individuals with higher education levels exhibit less cognitive decline in Alzheimer's disease due to increased brain adaptability and flexibility. The study, which analyzed autopsied brains of deceased participants, found a significant association between education and reduced AD pathology.
DuPont researchers developed a new way to make methyl isocyanate on site, reducing hazardous material handling by thousands of pounds. The approach has changed the company's handling of many hazardous chemicals, enhancing its environmental safety.
Researchers developed new methods for diagnosing breast cancer based on gene expression signatures, correlating with traditional pathological classifications. The study found that early-stage lesions contain molecular signatures reflecting tumor aggressiveness, potentially changing the course of cancer progression.
Scientists at UC Riverside have modified an existing full-scale chemical scrubber to a biological trickling filter, achieving treatment rates comparable to chemical scrubbers. The conversion resulted in annual savings of $30,000 per year, with potential for widespread adoption and significant cost benefits.
A new study has found that a 14-gauge automated tru-cut needle is highly accurate in diagnosing breast cancer, with over 99% accuracy rate. The study also showed that smaller biopsy needles can be just as effective as larger ones, offering a less invasive option for patients.
The Chemical Heritage Foundation has received a grant from the William Penn Foundation to support strategic planning. This funding aims to increase operating revenue and visitor numbers at the foundation's facility, as well as enhance online and on-site access to its library and archives.
David M. Holtzman and Ashley I. Bush have been awarded the 2003 Potamkin Prize for their work on amyloid accumulation and oxidation in Alzheimer's disease. Their research has provided essential basic foundation for understanding how to treat the pathology related to amyloid accumulation.
Bodner's approach to teaching chemistry emphasizes the importance of understanding the underlying ideas and history behind chemical concepts. He has successfully developed a division of chemical education at Purdue, which has granted over 40 doctorate degrees to graduates who become chemistry professors or train future teachers.
The American Chemistry Council predicts a second-half recovery for the chemical industry globally, with 3.5% growth in physical chemical volume expected this year. Basic chemical shipments are expected to grow 3.8%, with the fertilizer industry leading the way with a 5.0% increase.
Researchers at UNC School of Medicine successfully transdifferentiated rat stem cells into functional new tissue, including platelets, red blood cells, and heart muscle cells. This breakthrough finding may provide clues to the therapeutic potential of human adult stem cells for tissue repair.
The Chemical Heritage Foundation has received a $250,000 grant from the Rollin M. Gerstacker Foundation to support its oral history program. This funding will help preserve the history of the chemical industry and molecular sciences through recorded interviews with key players.
Harold A. Sorgenti receives the Petrochemical Heritage Award for his entrepreneurial and community leadership achievements in the petrochemical sector. The award recognizes his significant contributions to the modern sciences, industries, and economies.
Researchers at UT Southwestern and Children's will develop protocols and procedures for a thermocycler called GeneXpert, which rapidly processes and analyzes DNA samples. The new testing methods should allow children to leave the hospital sooner or avoid hospitalization altogether, with results available within hours.
Researchers found three distinct clusters of patients with different memory and brain profile patterns, suggesting multiple disease mechanisms. The 'cortical' subtype showed temporal lobe pathology, while the 'subcortical' subtype featured frontal-striatal region issues.
Richard W. Rees, a Wilmington researcher, has been awarded the Hero of Chemistry title by the American Chemical Society for his work on laminated safety glass technology that protects people from flying glass shards and other debris in explosions.
James R. Moran, a fellow at Solutia Inc., has developed a laminated safety glass that can absorb blast pressure and energy, protecting people from flying glass shards and debris in explosions. This technology was recognized by the American Chemical Society's Heroes of Chemistry program for its contribution to improving public safety.
Researchers at Washington University School of Medicine have found that a defective form of vWF causes chemical bonds to persist longer than they should, leading to a bleeding disorder. The defect in the vWF protein changes the kinetics of the chemical bonds between the protein and platelets, resulting in the disease.
The 'What's That Stuff?' column in Chemical & Engineering News is one of five top sites recognized by Scientific American for informative and engaging chemistry content. The column has been widely shared among scientists, students, educators, and industry professionals, who appreciate its ability to make everyday materials fascinating.
Researchers aim to find new targets in the brain to prevent and treat Alzheimer's and Parkinson's diseases using Serial Analysis of Gene Expression (SAGE) technology. The $2.75 million funding will support Columbia University's technology transfer and commercialization efforts.
The American Society for Colposcopy and Cervical Pathology has released comprehensive national consensus guidelines to evaluate women with abnormal Pap tests. The guidelines recommend utilizing new technologies, including liquid-based cytology and HPV testing, to standardize care.
Shun C. Fung, a senior engineering associate at ExxonMobil Research and Engineering Company, has received the American Chemical Society's Industrial Innovation Award for his work on improving catalyst reuse. His research enabled petroleum companies to capture and reuse expensive catalysts, passing millions of dollars in savings to cons...
Researchers found late-onset schizophrenia to be a distinct condition characterized by tau protein abnormalities. The study analyzed brain tissue from patients and found that changes in the hippocampus were caused by hyper-phosphorylation of tau.