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American Association for the Advancement of Science (AAAS)


Engineer and university administrator Gary S. May receives 2021 AAAS Lifetime Mentor Award

Gary S. May has received the 2021 AAAS Lifetime Mentor Award for his three-decade career as a professor of computer engineering and university administrator. He founded numerous programs to support underrepresented minority STEM students, mentoring over 100 Ph.D. candidates who are now leading positions in academia and industry.

Even in same desert location, species experience differences in exposure to climate warming

A new study reveals that despite living in the same Mojave Desert location, mammal and bird communities experience different exposures to climate warming. Small mammals have remained relatively stable, while bird occupancy and species richness have declined dramatically due to their limited ability to mitigate rising temperatures.

Uncovering recurring deletions in SARS-CoV-2 spike protein that drive antibody escape

Researchers identified recurring deletions in SARS-CoV-2 spike protein that prevent antibody binding, allowing viruses to evade the immune system. The study analyzed nearly 150,000 gene sequences and found instances of viruses with these deletions, which have repeatedly arisen in genetically distinct viruses worldwide.

Mammogram-based breast cancer risk model could lead to better screening guidelines

A new machine learning algorithm named Mirai estimates breast cancer risk in women more accurately than current models, identifying 41.5% of patients at risk within 5 years. The model was effective across various races and ethnicities, supporting its potential to inform screening guidelines for diverse populations.

SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience Translational Medicine·DateJan 27, 2021

New single-cell lineage tracing technique offers detailed insights into drivers of metastasis

A new method traces real-time cancer progression across thousands of cells, identifying rare events and distinct gene expression profiles associated with metastatic phenotypes. The approach could inform aspects of cellular cancer biology, including genetic mutations, microenvironment adaptation and resistance to therapeutic agents.

Algorithms designed to study language predict virus 'escape' mutations for SARS-CoV-2 and others

A new tool predicts viral escape mutations by analyzing the relationship between viruses and human immunity, as well as the structure of sentences in natural language. The algorithm achieves accurate results without prior training, identifying high-escape potential regions in SARS-CoV-2's Spike protein.

Earth's terrestrial ecosystems may transition from carbon sinks to carbon sources within decades

The study suggests that up to half of land ecosystems could reach a tipping point where they release more carbon than they absorb by 2100 under a business-as-usual emissions scenario. Biomes with high carbon storage, such as rainforests and Taiga forests, may lose over 45% of their carbon sink capabilities by midcentury.

Social transmission of pain, fear has different targets in mouse brain

Researchers discover pain and fear are transmitted through different brain regions in mice, with pain mediated by the anterior cingulate cortex to the nucleus accumbens and fear mediated by the ACC to the basolateral amygdala. This study provides insights into empathy and may offer a model for socially-induced pain relief among humans.