The study reveals that noradrenaline transporter forms a homodimer mediated by cholesterol and lipids, regulating substrate binding. Six different antidepressants bind to NET with overlapping but distinct modes, conferring subtype selectivity.
An international team used deep learning neural networks to identify rare weak signals in quasar spectral data. They discovered 107 extremely rare neutral carbon absorbers, doubling the number of samples found in 2015, and detected more faint signals than before.
The BESIII experiment has made the first measurements of the quantum numbers of X(2370), a particle consistent with a glueball. The study confirms the existence of glueballs, a crucial test of the Standard Model, and provides strong experimental evidence.
A global research team suggests that all eight baobab species originated in Madagascar due to genomic analysis. The most likely scenario is that baobabs dispersed from Madagascar when sea levels were lower, but rising sea levels could hinder their expansion and threaten their populations.
A new study has revealed the mechanisms behind hydrodynamic escape in low-mass exoplanets, which is a process that can lead to significant changes in a planet's mass and climate. The research proposes a new classification method for understanding these escape processes and provides insights into the habitability of distant worlds.
Chinese researchers have discovered huge magnetic toroids in the halo of the Milky Way galaxy using data from pulsars and radio telescopes. The study provides crucial constraints on the origin of cosmic magnetic fields and offers insights into the physics of our galaxy.
Scientists have discovered six high-redshift galaxies using the FAST telescope, finding significantly more atomic hydrogen gas than previously surveyed galaxies. This reveals that galaxies four billion years ago had more star-forming gas than current-day galaxies, challenging previous assumptions.
Researchers have discovered distinct ethanol-water molecular clusters that determine critical alcohol content ranges in various beverages. By controlling these clusters' transitions, manufacturers can maintain ideal taste while reducing alcohol concentration.
A study published in Science reveals two patterns of tumor-infiltrating B cell responses: germinal center-like and extra-follicular. The former is associated with anti-tumor immunity, while the latter is linked to an immunosuppressive tumor microenvironment. Researchers propose targeting atypical memory B cells for cancer immunotherapy.
Soil carbon dioxide emissions are more sensitive to climate warming in permafrost-collapsed areas, releasing about 5.5 times more CO2 than non-collapsed areas. The study found that thermokarst formation increases the temperature sensitivity of CO2 release.
Chinese scientists developed a new three-phase OSW electrocatalytic system for efficient production of high-purity benzaldehyde, achieving 97% Faradaic efficiency and 91.7% purity without post-purification processes. The system uses clean energy and water resources, simplifying product separation and purification.
A recent study published in Nature reveals a vast DNA tree of life for flowering plants, providing insights into their evolutionary history. The analysis of over 9,500 plant species reveals the rapid development of diversity in ancient times, with key findings supporting the plastid-based phylogenetic classification of angiosperms.
Targeted genome editing tools have revolutionized crop breeding methods, significantly improving breeding efficiency and precision. The latest advances in base editing, prime editing, and precise manipulation tools are expected to become critical foundational technologies for future crop research and breeding applications.
A new study by Chinese researchers has developed a high-energy-density aqueous battery using a mixed halogen solution as the electrolyte. The battery achieved a specific capacity of over 840 Ah/L and an energy density of up to 1200 Wh/L.
Scientists have developed a new method to efficiently extract information from galaxy surveys, enabling the use of high-order information in future studies. This breakthrough has significant implications for understanding dark energy, dark matter, and gravity.
Researchers demonstrated straight-sliding dynamics of electric current-driven antiskyrmions in a MnPtSn chiral magnet at room temperature and zero external magnetic field. The method allows for the manipulation of antiskyrmions in helical stripe domains, overcoming deflection by the Magnus force.
A recent study published in Science reveals a vast store of global soil inorganic carbon (SIC) amounting to 2,305 billion tons, surpassing vegetation's combined carbon content. This 'hidden pool' is vulnerable to environmental changes, posing significant risks to ecosystem functions and climate change mitigation strategies.
Scientists used lithium isotope data to show that continental clay export promoted organic carbon burial and thus atmospheric oxygenation during the Cambrian period. This finding challenges traditional views on marine oxygen levels during this time, suggesting a complex interplay between oceanic and atmospheric processes.
A team of researchers used a single-cell transcriptomic map to investigate the role of androgens in shaping sex differences. They identified genes influenced by androgens and found that group 2 innate lymphoid cells play a role in inflammation and disease susceptibility.
A study by Prof. LI Yu and colleagues reveals that glucose signals are essential for regulating thermogenic activity in beige adipocytes, which emerge in response to cold stress. The researchers identified the transcription factor CREB/ATF bZIP (CREBZF) as a key mediator of glucose effects.
A new study identifies the mechanism underlying N6-methyladenosine (m6A) RNA modification in mammals, revealing its role in regulating gene expression and promoting genome stability. The study found that DDX21 and METTL3 work together to facilitate m6A deposition co-transcriptionally.
Scientists have developed a method to precisely control the shape and contact angle of microdroplets, achieving arbitrary shapes and a wide range of contact angles. This breakthrough challenges the traditional Gibbs equation, which predicts contact angles for macro-droplets on rough surfaces.
Researchers discovered that neonatal spinal cord ECM significantly enhanced NPC proliferation, migration, and differentiation compared to adult ECM. This study highlights the critical role of early developmental spinal cord ECM in orchestrating spinal cord regeneration processes.
Researchers have discovered fossilized water striders in copulation, providing a rare glimpse into the mating behaviors of ancient insects. The study reveals strong sexual conflict between males and females, with males using specialized morphological adaptations to overcome female resistance.
Researchers describe two Jurassic mammaliaforms from China, revealing dental diversification and the emergence of middle ear ossicles. The findings support a classic example of vertebrate evolution and provide new insights into early mammalian phylogeny.
A new iron-based phosphate cathode material has been developed with improved reversible capacity and energy density, enabling fast-charge capability and superior cycling performance. The material uses a bi-phase intergrowth heterogeneous structure to activate the inert phase, achieving high capacity and long cycle life.
Researchers found a 100-million-year-old endoparasitic marine tapeworm fossil in Kachin amber, providing new information on the early evolution of tapeworms. The discovery shows that amber can preserve internal structures of helminths like tapeworms, shedding light on their taphonomy.
Researchers discover a significant association between chronic knee pain and accelerated brain aging, highlighting the need for early detection and intervention strategies. Brain regions critical for cognitive function show increased signs of aging in individuals with chronic musculoskeletal pain.
The study confirms the BZ-jet model accurately predicts the morphology of observed jets, including elongated structure and limb-brightening characteristics. The disk-jet model failed to explain these observations. The research bridges the gap between dynamic models and jet properties.
The study confirms the presence of four distinct subgenomes in woody bamboos, with the C subgenome dominating two tetraploid lineages. The hexaploid lineage exhibits a dynamic shift in dominance from C to A subgenomes, contributing to evolutionary traits and forest habitat adaptation.
Researchers found that our brains analyze submolecular features when we smell, leading to changes in perception over time. This dynamic adaptation affects the way our brains represent smells, making them less consistent than previously thought.
Researchers from Chinese Academy of Sciences have synthesized bulk van der Waals materials at near-room temperature using a low-energy method. This breakthrough reduces the energy consumption required for fabrication by at least one order of magnitude.
Researchers successfully tailored bubbles with different curvature to induce strain on MoS2, enhancing proton adsorption and HER kinetics. The study shows a substantial boost in HER activity, with values reaching 129.65 mA cm-2 compared to 48.11 mA cm-2 at -0.4 V vs. RHE.
Scientists have created a new approach for treating tendon-bone injuries by combining manganese silicate nanoparticles with cells to create an immunomodulatory scaffold. This innovation promotes integrated regeneration and functional recovery in patients, offering a promising solution for improving life quality.
Researchers have discovered distinct characteristics of the lower mantle flow field beneath the Philippine Sea Plate. They found that ancient N-S fast velocity directions exist at depths of 700-900 km and are not related to slab subduction or a mantle plume.
A new study identifies conservation priority areas for vascular plants in Madagascar, highlighting uneven distribution of taxon richness and phylogenetic diversity. The researchers found that arid and semi-arid regions lack protected areas, presenting additional conservation challenges.
Researchers found that neutrophils can adopt specialized functional states to present antigens to activate potent cancer-killing T cells. This discovery has significant implications for cancer diagnosis and treatment, potentially harnessing the diverse hidden identities of neutrophils.
A new study suggests that East Asian hominins possessed advanced knapping abilities equivalent to Mode 2 technological features as early as 1.1 million years ago. The research team discovered organized flaking techniques and standardized operational processes, indicating complex mental templates among the toolmakers.
The study of ancient genomes has shed light on the evolution of modern humans, revealing genetic changes that distinguish us from Neanderthals and Denisovans. These findings suggest that population-level advantages, such as increased connectivity and access to resources, played a significant role in shaping human migration patterns.
Researchers develop new method to fabricate anti-fatigue 3D-printed titanium alloy by regulating microstructure and defects, showing remarkably high fatigue resistance and specific strength. The study reveals potential advantages of 3D printing technology in producing structural components.
Scientists have discovered a giant ultra-high-energy gamma-ray bubble structure in the Cygnus star-forming region, indicating the presence of a super cosmic ray accelerator. The discovery is the first to reveal the origin of cosmic rays with energy higher than 10 Peta-Electronvolt.
Researchers have synthesized two new isotopes, osmium-160 and tungsten-156, which may indicate that lead-164 could be a doubly magic nucleus with increased stability. The study explores the relationship between proton number and decay rate, suggesting an enhancement of shell closure towards the proton drip line.
A new type of antifouling membrane spacer inspired by coral tentacles has been developed, reducing fouling by 61.7% and increasing efficiency. The spacer's low surface energy and temperature responsiveness improve hydration capacity and interfacial roughness control.
A study led by Chinese astronomers identified a previously unknown source of cosmic dust in the universe: Type Ia supernovae interacting with gas from their surroundings. The researchers found that these events create significant amounts of dust, which could be a dominant source of dust in elliptical galaxies.
A research team has observed and quantitatively characterized the many-body pairing pseudogap in unitary Fermi gases, resolving longstanding debates. This achievement supports pairing as a possible origin of the pseudogap in high-temperature superconductors, advancing our understanding of strongly correlated systems.
A new study of a 7–8-million-year-old extinct fossil ape from China, Lufengpithecus, offers new insights into the evolution of human bipedalism. The researchers found that early apes shared a locomotor repertoire ancestral to human bipedalism, and their analysis suggests a three-step evolution of human bipedalism.
Researchers developed highly efficient and stable perovskite light-emitting diodes using a solvent sieve method, achieving an operating lifetime of over 5.7 years and a record high external quantum efficiency of 29.5%. The study also demonstrated excellent stability in ambient air conditions.
Researchers analyzed 151 ecosystems across six continents to understand the intricate coexistence network among diverse species in soil ecosystems. They found that facilitative networks, characterized by positive associations, are more common than previously thought and play a key role in maintaining soil biodiversity.
A study published in Science reveals the spatial connectivity patterns of mouse hippocampal neurons at a single-neuron level. The researchers reconstructed the whole-brain axonal morphology of over 10,000 neurons, identifying 43 distinct projectome cell types and new projection patterns.
A study published in PNAS reveals that light controls the post-transcriptional splicing of genes regulating photosynthesis in mesophyll cells. This process is co-regulated by AtPRMT5 and COP1, allowing plants to adapt to changing light conditions.