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Duke University


Midwater ocean creatures use nanotech camouflage

Researchers discovered that midwater crustaceans have transparent bodies and optical coatings on their legs and bodies that reduce reflections by up to 250-fold. The coatings appear to be made of living bacteria, with each species having its own symbiotic optical bacteria. This discovery has potential technological applications.

SourceDuke University·JournalCurrent Biology·DateOct 27, 2016

Indian roadside refuse fires produce toxic rainbow

A Duke University study found that roadside garbage fires in India produce a toxic rainbow of pollutants, with concentrations 1,000 times greater than ambient air. The variability in emissions stems from the diverse trash materials and smoldering combustion, highlighting the need for improved waste management practices.

SourceDuke University·JournalAtmospheric Environment·DateOct 25, 2016

Male mice model human speech defect

Researchers at Duke University found that male mice carrying a genetic mutation known to affect human speech struggle with sequencing phonemes into words. The study used new statistical tools to analyze the structure of ultrasonic mouse songs, revealing a similar impact on sequence complexity as seen in humans.

SourceDuke University·JournalFrontiers in Behavioral Neuroscience·DateOct 20, 2016

Chemical tags affect ability of RNA viruses to infect cells

New research from Duke University found that RNA viruses like hepatitis, Zika, and dengue are littered with N6-methyladenosine tags which slow down their ability to infect cells. The study suggests that these chemical tags might regulate the life cycle of these viruses and provide new targets for antiviral drug development.

SourceDuke University·JournalCell Host & Microbe·DateOct 20, 2016

Dust mite allergens share rare combo of qualities

Researchers at Duke University and NIEHS discover that dust mite allergens are both more abundant and stable than non-allergenic proteins, which may lead to new allergy treatments or predict allergenic potential of artificially added proteins. This discovery could also help characterize disease states and study drug mode-of-action.

SourceDuke University·JournalJournal of Allergy and Clinical Immunology·DateOct 19, 2016

Bacterial genes boost current in human cells

Researchers at Duke University have successfully delivered bacterial genes to human cells, enhancing electrical signaling and making cells more excitable. The technique could one day be used to treat cardiac arrhythmia, restore electrical functions to scarred tissues, or improve conductivity in genetic diseases.

SourceDuke University·JournalNature Communications·DateOct 18, 2016

Identity beats policy when it comes to voter choices

A new theory proposes that social identity and policy positions compete to shape voter choice. This model explains why voters often select candidates whose policies contradict their own interests, as people prioritize their self-image and social media signals over the practical benefits of voting.

SourceDuke University·JournalTrends in Cognitive Sciences·DateOct 18, 2016

Lego-like wall produces acoustic holograms

Researchers at Duke University have developed a simple, energy-efficient way to create three-dimensional acoustic holograms using Lego-like metamaterials. The technique manipulates sound waves into desired patterns, enabling applications such as improving sound quality in speakers and creating realistic ultrasound images.

SourceDuke University·JournalScientific Reports·DateOct 14, 2016

Could mental math boost emotional health?

A new brain-scanning study found that engaging a specific part of the brain during mental math exercises is connected with better emotional health. The study suggests that this ability may reflect the brain's capacity to regulate emotions like fear and anger, and could inform new brain training strategies.

SourceDuke University·JournalClinical Psychological Science·DateOct 10, 2016

Holographic imaging and deep learning diagnose malaria

A new technique using computer 'deep learning' and light-based, holographic scans can spot malaria-infected cells from simple blood samples, offering fast and reliable diagnosis in resource-limited areas. The method was tested on hundreds of cells and accurately identified malaria 97 to 100 percent of the time.

SourceDuke University·JournalPLOS ONE·DateOct 6, 2016

Acclaimed health program fails to help children in India

A large-scale study by Duke University researchers found that India's World Health Partners (WHP) Sky program had no impact on improving healthcare for children with diarrhea and pneumonia. Despite its $23 million funding, the program failed to increase access to proper treatment or change healthcare utilization patterns.

SourceDuke University·JournalHealth Affairs·DateOct 4, 2016

A tour de (tiny) force

A new study at Duke University reveals that applying a tiny force to the Piezo1 receptor can change its behavior while it's already activated. The researchers used magnetic fields and nanometer-sized beads to manipulate the protein, which sits on cell membranes and plays a crucial role in sensing forces surrounding cells.

SourceDuke University·JournalNature Communications·DateOct 3, 2016

Oxytocin enhances spirituality, new study says

A recent study published in Social Cognitive and Affective Neuroscience suggests that oxytocin may support spiritual beliefs by enhancing feelings of awe, gratitude, and hope. Men who received oxytocin reported a stronger sense of spirituality and interconnectedness with others, regardless of their religious affiliation.

SourceDuke University·JournalSocial Cognitive and Affective Neuroscience·DateOct 3, 2016

Variation in 'junk' DNA leads to trouble

A new study reveals that variation in repetitive genetic code, once considered 'junk', can affect genome stability and lead to an increased risk of cancer, birth defects, and infertility. The research found that genomic variation at specific regions determines the location of centromeres on human chromosomes.

SourceDuke University·JournalGenome Research·DateAug 30, 2016

Hormone activation of genes takes teamwork

A team of Duke scientists used DNA-sequencing and computerized biology to study the glucocorticoid receptor's signaling system. They found that only 13% of binding sites directly respond to hormones, while the remaining 87% act as clusters that amplify signals.

SourceDuke University·JournalCell·DateAug 25, 2016

Analog DNA circuit does math in a test tube

A new study by Duke University researchers creates an analog DNA circuit that can add, subtract and multiply in a test tube, using concentrations of specific DNA strands as signals. The technology has the potential to be used in diagnosing and treating diseases, with applications including sensing vital signs and detecting molecular si...

SourceDuke University·JournalACS Synthetic Biology·DateAug 23, 2016

Targeting the gut-brain connection can impact immunity

A study by Duke University researchers found that manipulating dopamine signaling can control inflammation in the gut, providing a proof of principle for using drugs originally designed to target the nervous system to treat immune system disorders such as rheumatoid arthritis and autoimmune disease.

SourceDuke University·JournalCurrent Biology·DateAug 11, 2016

Directly reprogramming a cell's identity with gene editing

Duke researchers have successfully converted mouse fibroblasts into neuronal cells using a modified CRISPR technique. This breakthrough could lead to improved models for neurological disorders and personalized medicine. The study's findings suggest that the newly generated neurons retain their properties even after the CRISPR activator...

SourceDuke University·JournalCell Stem Cell·DateAug 11, 2016

Lemur DNA paints a picture of Madagascar's forested past

Researchers at Duke University used fast-changing mouse lemur DNA to paint a picture of Madagascar's forested past. The study suggests that the island was not as tree-covered as previously thought, with grasslands and woodlands dominating the center of the island before human arrival.

SourceDuke University·JournalProceedings of the National Academy of Sciences·DateJul 18, 2016

Study points to fast-acting drug for OCD

A Duke University study found a single chemical receptor in the brain responsible for OCD symptoms in mice. The receptor, mGluR5, was found to be overactive in mice with Sapap3 gene deletion, which mimics human OCD. When blocked, symptoms abated immediately.

SourceDuke University·JournalBiological Psychiatry·DateJul 15, 2016

Disentangling the plant microbiome

A new study led by researchers at Duke University found that breeding plants with beneficial bacteria to feed the world won't be simple. The study analyzed the microbial diversity of a wildflower and found that environmental differences had the biggest influence on the plant's bacterial makeup.

SourceDuke University·JournalNature Communications·DateJul 12, 2016

Precise control of brain circuit alters mood

Researchers at Duke University have developed a new method to control a specific brain circuit in mice, which can alter their mood. By combining super-fine electrodes and tiny amounts of a specific drug, the team was able to restore stressed animals to relatively normal behavior.

SourceDuke University·JournalNeuron·DateJun 23, 2016