Emory University licensed its ERTb software to Syntermed for enhanced cardiac imaging, utilizing SPECT technology to diagnose coronary artery disease. The software improves image quality, accuracy, and patient outcomes in cardiovascular diagnosis and prognosis.
Researchers discovered that acyclovir directly suppresses HIV-1 in tissues co-infected with several herpesviruses. The activated form of acyclovir inhibits the HIV-1 reverse transcriptase, necessary for viral replication. This finding holds promise for developing new anti-HIV treatments combining acyclovir with other therapies.
Breakthroughs in cytogenetic technologies have enabled a new level of detail and accuracy in diagnosing complex developmental problems in children. Researchers are now using these tests to identify microdeletions and microduplications, leading to more accurate diagnoses and effective treatments.
Researchers have developed new therapies targeting out-of-control growth circuits in cancer cells, leading to improved survival rates. Advances in understanding head and neck cancer have also allowed doctors to better preserve organ function and increase early detection strategies.
A pilot program identified and treated college students with severe depression, saving lives through a suicide prevention outreach initiative. The study found that online dialogue features and secure websites reduced stigma and increased treatment rates among high-risk students.
Researchers at Emory University School of Medicine discovered that human arteries play distinct roles in the immune system depending on their anatomical location. Different types of arterial samples had varying Toll-like receptor gene expressions, which may explain why certain vascular diseases affect specific parts of the body.
Researchers at Yerkes National Primate Research Center created an animal model to study the effects of chronic stress on behavior, physiology, and reproduction. Corticotropin-releasing factor (CRF) is a key neurohormone involved in stress response, and its increased expression is linked to anxiety, depression, and infertility.
Scientists at Emory University School of Medicine have identified a crucial protein called UHRF1 that acts like a bookmark to maintain the correct pattern of DNA methylation. This process is essential for normal development and preventing cancer, as alterations in methylation patterns can lead to gene silencing at the wrong times.
A new study reveals that experienced Zen meditators can quickly clear their minds of distractions compared to novices. After being interrupted by a word-recognition task, experienced meditators' brains returned faster to their pre-interruption condition.
A study has identified a new gene that may play a key role in the development of pediatric-onset inflammatory bowel disease. The gene, TNFRSF6B, is involved in regulating inflammation and its activity has been linked to the severity of the disease.
Monkeys predominantly chose sharing tokens with relatives and familiar individuals, showing empathy-driven prosocial behavior. The study suggests that giving may be self-rewarding for monkeys due to social closeness.
A study published in JAMA found that former child soldiers in Nepal are more likely to experience symptoms of depression and PTSD, with 53% meeting symptom cutoff scores for depression. The researchers suggest that the reintegration process may be a contributing factor to their mental health problems.
Researchers at Yerkes National Primate Research Center and Emory Vaccine Center found that trapping white blood cells in lymph nodes can help mice fight chronic viral infections. FTY720, an experimental drug, prevents white blood cells from leaving lymph nodes, improving immune response against the virus.
A team of researchers has found that trapping white blood cells in the lymph nodes can help mice overcome a chronic viral infection. Experimental drug FTY720, also known as fingolimod, prevents white blood cells from responding to the virus by desensitizing them to sphingosine-1-phosphate.
A study by Emory University researchers found that black girls who abused alcohol had low condom usage rates, even after participating in HIV interventions. The study suggests that addressing alcohol use is crucial to developing effective HIV interventions for this demographic.
Researchers found that girls who participated in the HORIZONS intervention were less likely to contract a STD and more likely to consistently use condoms during sex. The study suggests that gender-tailored and culturally-congruent interventions can reduce bacterial STD infections and enhance HIV-preventive behaviors.
A study by Emory University researchers found that black girls who use marijuana have significantly higher rates of incident STDs than non-users. Marijuana users also had more sex partners and riskier sex acts, including those with recently released jail partners.
A study of HIV-infected crack users found that nearly half reported unprotected sex in the last six months, highlighting a pressing need for targeted interventions. The five-year HOPE study aims to improve engagement in care and prevention services, particularly for female users.
Respiratory illnesses, such as the common cold and pneumonia, were the primary diagnoses for travelers in China. Dog bites were also a significant concern, with 400 reported cases over 10 years, leading to rabies vaccination needs. Travelers can minimize risks by planning ahead, using common sense, and taking necessary vaccinations.
A study published in Biological Psychiatry found that deep brain stimulation (DBS) in the subcallosal cingulate region significantly improves symptoms of treatment-resistant depression. The procedure showed continued and sustained benefits over time, with no long-term side effects reported.
Emory University researchers have discovered that fluoroquinolone antibiotics can enhance the effectiveness of RNA interference, a gene-silencing technique, in laboratory settings. The most powerful enhancer was enoxacin, which has been used to treat bacterial infections.
Researchers have discovered that a natural compound from magnolia cones can block a previously 'undruggable' pathway for cancer growth. This finding could lead to the development of new treatments by making tumors more sensitive to traditional chemotherapy drugs.
Researchers identified sequence variations in the ARP gene that allow differentiating venereal syphilis from non-venereal Treponema pallidum subspecies. The findings have significant clinical, epidemiological and evolutionary implications.
Researchers have identified a crucial protein that transports signals within neurons, shedding light on Fragile X Syndrome's impact on brain development and communication. This breakthrough could lead to the development of innovative treatments for FXS, autism, and epilepsy.
Scientists have found a gene, MagA, that allows mammalian cells to produce tiny magnetic particles, making them visible under magnetic resonance imaging (MRI). The gene shows potential as an imaging tool for tracking cells' movement through the body.
Researchers at Emory University developed an intrabody that binds to mutant huntingtin, reducing clumps and alleviating motor problems in mice. The study suggests a strategy for dissecting harmful effects of protein aggregates in other neurodegenerative diseases.
Scientists have identified CAML as a human host restriction to HIV release, which can now be overcome by Vpu. This discovery may lead to new treatments for HIV, as researchers are working on defining the mechanism and developing therapies.
Researchers at Yerkes National Primate Research Center have developed the first transgenic nonhuman primate model of Huntington's disease, a devastating neurodegenerative disorder. The model is expected to help researchers better understand the disease and develop more effective therapies.
Scientists have discovered conclusive evidence of Alzheimer's-like neurofibrillary brain tangles in an aged nonhuman primate, a breakthrough that could help understand why humans develop neurodegenerative diseases. The finding also paves the way for new treatments and therapies targeting beta-amyloid protein.
Researchers found socially subordinate females consume calorie-rich foods at a higher level, leading to accelerated weight gain and increased fat-derived hormones. Dr. Wilson believes this may be linked to changes in metabolism and cortisol levels.
A study by Emory University researcher Jacobus de Roode found that higher levels of replication within the host result in both increased virulence and greater transmission of parasites. This suggests that natural selection selects for harmful parasites, prioritizing their fitness over host health.
Scientists at Emory University's Winship Cancer Institute discovered a new regulation mechanism in breast cancer cells responding to estrogen. The study found that methylation on estrogen receptors prolongs their life and effectiveness in driving tumor growth.
Researchers have developed a faster way to generate human monoclonal antibodies against influenza virus by tapping the immune system at peak powers. The method was tested on human volunteers and showed promising results, potentially finding broad application towards almost any infectious disease.
A team of scientists has identified new non-histone targets for a protein methyltransferase enzyme, expanding our understanding of epigenetic regulation in cells. The discovery broadens the view on methyltransferases and indicates that epigenetic gene regulation is more complex than previously thought.
A study of over 660 operations found that minimally invasive pancreas surgery resulted in fewer complications, shorter hospital stays, and lower blood loss compared to traditional surgery. The approach has also been shown to be viable for the surgical care of other organs.
Researchers used a transgenic fruit fly model to study how Salmonella evades immune defenses, finding that the protein AvrA shuts down key signaling pathways. This allows the bacteria to cause severe intestinal infections. The study's results suggest that other pathogens may target similar biochemical networks to avoid elimination.
Researchers at Emory University found that supplementing diet with calcium and vitamin D increased levels of protein Bax, which controls programmed cell death in the colon. This increase may push pre-cancerous cells into programmed cell death, potentially reducing colon cancer risk.
A new study led by Emory University researcher Charles L. Raison found that Tibetan refugees, especially those born in Tibet, experience high levels of depression and anxiety. The study also showed that time spent in India can improve symptoms, but the emotional trauma remains a concern.
Researchers found that increasing production of angiotensin-converting enzyme in macrophages enhances the immune system's ability to sense and respond to tumors. This discovery suggests a strategy for amplifying immune system function in humans, potentially enhancing cancer patients' ability to resist tumor growth.
Researchers have identified a key player in the killing of brain cells after a stroke or seizure - asparagine endopeptidase (AEP). AEP unleashes enzymes that break down brain cells' DNA, causing permanent damage.
Researchers at Yerkes National Primate Research Center have identified a unique language feature in the human brain that differs from our closest living relative, the chimpanzee. The study used DTI to compare human brain structures and found a larger and more widespread projection of fibers in the middle temporal lobe.
Researchers at Emory and Children's Healthcare of Atlanta are partnering with UCLA and Stanford hospitals to develop new ways to make kidney transplants more tolerable for children. The goal is to create a simple blood or urine test to inform doctors whether kidney rejection is 'revving up,' possibly avoiding painful biopsies.
Scientists have identified nine molecules that reverse the features of fragile X syndrome in fruit flies, including deficits in learning centers and behavioral deficits. The screening also uncovered other neural pathways that may be targeted for drug therapy.
Australian researchers have discovered ancient crayfish fossils, providing evidence that the crustaceans existed on the continent as far back as the Mesozoic Era. The finds offer insights into the ecology of southern Australia during this period, which saw diverse plants and dinosaurs in prolonged polar darkness.
A recent study found that adults who were abused in childhood and carried a specific gene variant showed lower measures of depression. The gene variant, corticotropin-releasing hormone receptor one (CRHR1), appears to protect against depression in adults who experienced moderate to severe child abuse.
Researchers developed a novel anticancer strategy targeting PI-3 kinases, which are crucial for cancer cell growth and survival. The compound, SF1126, showed efficacy in seven types of tumors in mice and is being tested in human clinical trials.
Researchers have identified a key gene, 14-3-3zeta, that enables lung cancer cells to survive on their own. Silencing this gene has been shown to inhibit the growth and survival of lung cancer cells, making it a potential target for selective anti-cancer drugs.
Researchers have developed gold nanoparticles with antibody fragments that can identify tumors in living animals. The particles emit a specific signal when illuminated by a laser beam, enabling early detection of cancer. This technology offers a non-invasive and potentially more effective approach to cancer diagnosis.
Researchers are using patients' own bone marrow stem cells to treat cardiac muscle damage after a heart attack. The study, funded by biotech company Amorcyte, has progressed halfway through its four planned groups of patients and aims to assess the safety and feasibility of harvesting bone marrow cells.
A recent study found that chronic alcohol consumption by lung donors promotes scarring and airway injury after transplantation. The research, published in the American Journal of Respiratory and Critical Care Medicine, raises questions about human lung donors with a history of alcohol abuse.