A new radiological diagnostic tool called stereo mammography reduces false-positive findings by 49% and missed lesions by 40%. The technology cuts the number of women recalled for additional tests in half, eliminating anxiety for patients and their loved ones.
Research at Emory University found that therapeutic drug monitoring for lamotrigine during pregnancy reduces increased seizure activity and improves health outcomes. The study's findings suggest a potential benefit for pregnant women with epilepsy, allowing for targeted dosage adjustments to minimize risk.
Researchers discovered that abnormal glutamine repeats interfere with key transcription factor TBP, leading to neurodegeneration in PolyQ diseases. The study provides insight into the molecular mechanisms underlying these inherited disorders.
Paleontologists from Emory University have discovered large carnivorous dinosaur tracks in Victoria, Australia, revealing that these dinosaurs roamed a polar environment. The tracks are estimated to be around 115 million years old and suggest that dinosaurs were larger than previously thought.
A new method called Microarray-based Genomic Selection (MGS) allows researchers to extract and enrich specific large-sized DNA regions for resequencing. This technology enables the detection of subtle genetic variations that may have serious consequences for health and disease.
Researchers identified key brain regions involved in fine tactile spatial discrimination, including the right posteromedial parietal cortex and right posterior intraparietal sulcus. The study's findings may lead to the development of sensory-substitution devices for visually impaired individuals.
Researchers at Emory University School of Medicine will use advanced technologies to search the entire X chromosome for genetic abnormalities in 330 patients with autism. The goal is to identify X-linked variation for autism susceptibility, a crucial step towards developing diagnostic tests and therapeutic approaches.
A new flu vaccine delivered through painless microneedles in patches applied to the skin could soon be an alternative to hypodermic needles, offering less discomfort and lower costs. The Emory University and Georgia Institute of Technology team aims to design patches that can increase immunity to influenza with smaller amounts of vaccine.
Researchers identified gambogic amide, a compound in tree bark, that mimics NGF's effect on brain cells by binding to TrkA. This finding suggests potential as a therapeutic treatment for neurodegenerative diseases such as Alzheimer's and stroke.
A recent study found that chronic viral infections can persist by targeting fibroblastic reticular cells (FRC) in lymphoid organs, disrupting the function of these cells. The researchers discovered a potential link between this mechanism and the PD-1 pathway, which may inhibit immune responses to chronic infections.
Researchers identify fundamental brain defect in fragile X syndrome and find a potential drug target using a therapy that reverses the effects of the mutation. The discovery could lead to human therapies for this previously untreatable condition.
Emory researchers identify Ribosomal S6 kinase 2 (RSK2) as a critical downstream signaling protein effector of FGFR3 in myeloma cells. RSK2 plays a key role in regulating cell cycle and survival, and targeting it with drugs may be effective in treating multiple myeloma.
Researchers found that reactive oxygen stimulates dendritic cells to up-regulate the immune antigen CD80, leading to T cell activation and increased TNF production. This causes excessive destruction of bone via osteoclasts.
A new study found a strong link between reduced levels of LR11 in the brain tissue of individuals with mild cognitive impairment (MCI) and the onset of Alzheimer's disease. The findings suggest that LR11 may be a biomarker for predicting disease progression and a potential therapeutic target.
Researchers found a repeating pattern of 8 to 10 base pairs between CG dinucleotides that may signal differential methylation and imprinting. This discovery sheds light on the mechanisms of gene regulation and has implications for understanding disease development, particularly in cancer genes.
A team of researchers is using cutting-edge neuroimaging technology to identify predictors of adaptive functioning in adults who survived pediatric brain tumors. The study aims to develop interventions to lessen the severity of late effects of treatment and optimize adaptive functioning across the patient's lifespan.
The Emory research team aims to identify protein biomarkers that correlate with ALS onset and progression. Developing such biomarkers could enable early diagnosis, disease monitoring, and potential prevention of the disease.
Researchers identify pur alpha protein as key player in FXTAS, a neurodegenerative disorder caused by CGG repeats in the FMR1 gene. The protein's sequestration leads to toxic brain aggregates and movement problems.
Researchers found a link between the loss of norepinephrine and dopamine neurons and delayed Parkinson's symptoms. The study showed that both types of neurons are necessary for normal motor function.
Researchers led by Eric Weeks found that glasses are solid-like because they can't move when the sample chamber is thinner than typical group size. The study uses particles rather than atoms to directly observe how confinement influences glass transition, providing a simple framework for understanding other questions about glass.
A team of researchers defined how metal ions bind to amyloid fibrils in the brain, appearing toxic to neurons. The findings suggest that only one way of binding appears toxic, while others may be harmless.
Researchers found that lymphoid chemokines, which guide immune cells to lymph nodes and spleen, are reduced during active immune responses, potentially leading to transient immune suppression. This discovery could help explain why the immune system is less effective at responding to secondary infections after an acute infection.
A study published in the New England Journal of Medicine identifies a genetic link to Restless Legs Syndrome (RLS), a common sleep disorder. The gene variant is found to be associated with at least 50% of RLS cases, and nearly 65% of the population carries at least one copy.
A study found that older patients with stable cardiovascular disease can benefit from high-dose statins, which lowered LDL cholesterol levels and reduced the risk of major cardiovascular events. The study suggests that aggressive use of high-dose statin therapy can be beneficial for these patients.
The International Association of National Public Health Institutes (IANPHI) has awarded short- and mid-term technical assistance grants to public health institutes in five nations. The grants aim to support the development of national public health institutes and improve service delivery and decision-making globally.
A novel signaling pathway has been identified as being altered by genetic mutations in Parkinson's disease, affecting cellular function and potentially leading to new therapeutic targets. The research found that mitochondrial protein PINK1 plays a crucial role in protecting cells from oxidative stress and promoting cell survival.
A study by Emory University researchers has found a significant association between restless legs syndrome and high blood pressure. People with moderate to severe RLS are at increased risk for developing hypertension, with the likelihood of hypertension increasing by 50 percent in those who experienced over 30 PLMs per hour of sleep.
Patients with advanced-stage cancer struggle with maintaining both sleep and waking states, experiencing reduced nocturnal sleep quantity and quality. Demographic factors, such as age, education level, and marital status, may play a role in poor sleep outcomes among this population.
Researchers found that female mice with given birth had better auditory neurons at detecting and discriminating pup calls. The study suggests the brain improves information processing for specific communicative functions.
Researchers confirm captive chimpanzees can adopt and pass on complex behaviors, demonstrating a capacity for cultural variation similar to that observed in the wild. This finding supports the idea of common ancestry between humans and chimpanzees, highlighting their shared potential for cultural complexity.
International studies show high efficacy for HPV vaccine. The vaccine is highly effective in preventing pre-malignant changes of the cervix and protects against serious HPV-related diseases, including high-grade cervical pre-cancers.
A study of over 3,000 adults with asthma found that obese patients are more likely to have severe asthma and experience increased healthcare utilization. The researchers also noted that obese patients were less likely to be in asthma remission compared to non-overweight patients.
A minimally invasive device for stress urinary incontinence has been shown to be safe and effective in early clinical trials, demonstrating significant continence improvement in women. The device, ACT, eliminates the risk of overtreatment or undertreatment with adjustable balloons that can be adjusted post-operatively.
Researchers analyzed 30 years of data to understand how initial processes shaped the virus's geographic spread, revealing key factors like mountain ranges and rivers affecting its expansion. The study provides insights into the epidemiology of rabies and other emerging zoonotic diseases.
Researchers reprogram E. coli to detect and follow specific chemical signals, opening new frontiers in environmental cleanup and drug delivery. The custom chemo-navigational system could be used to target diseased cells while sparing healthy ones.
A new HPV vaccine has shown near 100 percent efficacy in preventing the two types of human papillomavirus responsible for most cases of cervical cancer. The vaccine targets HPV types 16 and 18, causing about 70 percent of all cases of cervical cancer.
A common genetic variation on chromosome 9p21 is linked to a substantial increase in risk for heart attack, with individuals carrying the variation having a 1.64-fold greater risk of suffering a heart attack. The study found that approximately 21 percent of individuals of European descent carry two copies of the genetic variation.
Researchers found bonobos and chimpanzees use manual gestures more flexibly than facial expressions and vocalizations. The study suggests bonobos engage in multi-modal communication, combining gestures with facial expressions and vocalizations to convey a message.
The study aims to identify ways to diagnose and treat aging-related diseases earlier, using chimpanzees and rhesus macaques compared to humans with Alzheimer's disease and mild cognitive impairment. The researchers hope to develop new treatments based on specific physiological changes.
Researchers found men are more likely than women to first look at a woman's face in sexual photos, while women focus longer on male-performed acts. Hormonal states also influence attention, with women using contraceptives looking more at genitals.
Researchers found females outperform males in using landmarks for navigation, even with blocked testosterone levels. This study provides insight into brain development and may lead to better treatments for disorders like ADHD and Alzheimer's.
Scientists have discovered that a cell-signaling molecule Akt plays a key role in the progression of melanomas from non-invasive to invasive cancers. Understanding this molecular difference could lead to new targets for treating advanced stage melanoma, with a survival rate of 98% for radial melanomas on the surface of the skin.
The Emory Global Health Institute is collaborating with the International Center for Genetic Engineering and Biotechnology in India to combat the deadly HIV/TB co-infection. The partnership aims to develop a therapeutic vaccine for individuals already infected, addressing a major public health concern.
Researchers at Emory University have developed an algorithm that can predict which sensitized patients on the national waiting list for kidney transplants are compatible with a given donor. This new method, based on innovative technology, has increased transplant rates from 15% to 25% in highly sensitized patients.
Researchers at Emory Health Sciences are developing pig islets as an alternative to human islets for transplant into patients with Type 1 diabetes. Successful development of porcine islet transplants could begin clinical trials within the next three years.
African scientists will receive training in drug discovery techniques to combat diseases such as HIV, tuberculosis, and malaria. The program aims to develop affordable, effective drugs using low operating costs and socially conscious investments.
Researchers found that increasing connexin26 in mice with missing connexin30 restored hearing sensitivity and prevented hair cell death. The discovery suggests a potential drug treatment for congenital deafness, which may replace gene therapy.