This study evaluated three-dimensional changes in the mandible and glenoid fossa of skeletal Class III patients treated with bone-anchored maxillary protraction. The results showed posterior displacement of the mandible and remodeling of the glenoid fossa, suggesting a favorable control of mandibular growth.
Researchers found that Fuz plays a crucial role in regulating craniofacial development, with defects leading to severe deformities. The study also highlights the importance of Fuz in negative feedback loops of canonical Wnt signaling.
A symposium at the International Association for Dental Research conference will present cutting-edge technologies to minimize caries damage and potentially eradicate caries disease. High-level evidence supporting new approaches will be discussed, including their potential effects on future healthcare costs.
A study of 523 patients aged 6-17 years found that non-operative sealing of manifest occlusal caries lesions resulted in a significant reduction in caries progression and improvement in tooth health. The results indicate the possibility of extending the criteria for non-operative sealing, but further observation is needed.
Two large studies on osteonecrosis of the jaw (ONJ) published in the IADR/AADR Journal of Dental Research investigate risk factors and prevalence. The studies found that bisphosphonate use is strongly associated with ONJ, and patients with oral bisphosphonates are 15.5 times more likely to have ONJ.
NIDCR funding to US dental schools decreased by 10% between 2005 and 2009, with dollars from other NIH Institutes and Centers increasing 34.6%. This trend may threaten the identity of dental schools as a profession if research infrastructure is not strengthened.
The American Association for Dental Research (AADR) presented a record-breaking turnout of 22 scientific posters on cutting-edge salivary diagnostics research. Key findings included emerging technologies and translational applications in the field, marking a significant milestone for the organization.
A large randomized clinical trial found FGF-2 to be effective in regenerating human periodontal tissue destroyed by periodontitis. The study showed substantial restoration of tissues with positive outcomes over the long term, making it an attractive approach for restoring lost tissues.
A recent study published in the Journal of Dental Research has identified genetic variations in taste pathway genes as predictors of tooth decay. The researchers found associations between TAS2R38 and TAS1R2 genes and caries risk or protection.
Research finds key gene expression pathways involved in Candidiasis-associated denture stomatitis, with significant up-regulation of TLR2 and CD28 signaling. Saliva analysis reveals six extracellular protein genes linked to stomatitis.
Researchers have developed a functional implantable artificial salivary gland to treat xerostomia in cancer patients. The new treatment uses modified hydrogels to regenerate functional salivary acinar cells, restoring saliva production and improving oral health.
A recent study suggests that Porphyromonas gingivalis (P.g.) infection may contribute to the chronicity of inflammatory disorders leading to oral cancers. The research found that P.g. induces expression of immune-regulating receptors B7-H1 and B7-DC in squamous cell carcinoma cells, facilitating immune evasion.
The Journal of Dental Research (JDR) has maintained its number one ranking in the 'Dentistry, Oral Surgery & Medicine' category, according to the new 2009 Five-Year Scientific Impact Factor (SIF) rankings. The JDR's SIF increased from 3.966 to 4.195, demonstrating its continued importance and relevance in the field.
Researchers have successfully established induced pluripotent stem (iPS) cells from dental pulp cells, a potential source for regenerative medicine. The study found that these cells can be easily obtained and expanded under simple culture conditions, making them an attractive option for cell therapy approaches.
The 2010 IADR/GSK Innovation in Oral Care Awards recognized three researchers for their innovative work on antimicrobial coatings, citrus-based treatments, and point-of-care diagnostic tools. These awards will support the development of new technologies to prevent and treat oral diseases.
Researchers found that periodontal pathogens activate HIV-1 promoters in T-cells, monocytes/macrophages, and dendritic cells. TLR2 and TLR9 play a key role in this response.
Researchers report that OSCC cells produce high levels of VEGF, promoting proliferation and invasion. A subpopulation of OSCC cells may undergo an epithelial-to-endothelial transition, facilitating tumor progression and metastases.
A study published in Journal of Dental Research found that successful periodontal treatment significantly lowers the risk of preterm birth. Pregnant women with periodontal disease who received scaling and root planing had a lower rate of prematurity compared to those without periodontal disease.
A team of researchers has created a new in vitro model for studying the effects of light on wound healing. They found that exposure to blue-violet light increases mitochondrial activity, cell proliferation, and growth factor secretion in human epidermal keratinocytes. These results suggest that blue light may be useful in enhancing epi...
The American Association for Dental Research (AADR) awarded John Greenspan the 2010 Distinguished Scientist Award for his groundbreaking research on HIV and its impact on oral health. Greenspan is a renowned expert in the field of oral pathology, having made significant contributions to the development of AIDS research.
Isabel Gay, assistant professor at University of Texas Health Science Center at Houston, receives AADR William B. Clark Fellowship for studying host genetic factors underlying diabetes and periodontal diseases in Mexican-Americans.
The American Association for Dental Research (AADR) is recognizing Senator Tom Harkin's commitment to National Institutes of Health (NIH) and National Institute for Dental and Craniofacial Research (NIDCR), doubling the NIH budget and securing $10.4 billion for research.
Irwin D. Mandel, a renowned researcher and mentor, received the inaugural AADR Distinguished Mentoring Award in 2010. The award recognizes his long-term dedication to fostering and promoting research training and career development among students, trainees, and junior faculty.
The American Association for Dental Research (AADR) has awarded David C. Johnsen, dean of the University of Iowa College of Dentistry, with the 2010 Jack Hein Public Service Award. Johnsen is recognized for his tireless advocacy for oral health research funding and training.
Dolphus Dawson, III, receives the 2010 AADR Neal W. Chilton Fellowship for biostatistical analysis of a dataset from the Effects of Periodontal Therapy on Preterm Birth (OPT) study. The analysis will investigate associations between clinical measures and preeclampsia in the OPT study population.
A study published in the Journal of Dental Research found that salivary bacterial populations were significantly different in overweight women compared to healthy individuals. The presence of certain bacterial species, such as Selenomonas noxia, was linked to an increased risk of obesity.
Scientists at Boston University discovered Resolvins, a new family of biologically active products of omega-3 fatty acids with therapeutic potential. These compounds have been shown to resolve periodontal inflammation and regenerate tissues in experimental gum disease models.
A study of 36,903 men found significant associations between obesity measures and periodontal disease. Obesity was associated with a 25% and 29% increased risk of periodontal disease compared to normal weight, with waist circumference and waist-to-hip ratio also linked to an increased risk.
Researchers have developed a method to generate complex, multilayer oral tissues using human embryonic stem cells. The tissues mimic normal oral cavity tissues and show promise for treating oral diseases through transplantation.
Studies link periodontal disease to infant prematurity, diabetes, and stroke. Treating pregnant women with scaling and root planing can save nearly $14 million worldwide.
A study found that periodontal disease caused by Porphyromonas gingivalis can reactivate latent HIV-1 in infected individuals. The bacteria induce histone acetylation, leading to HIV-1 reactivation. Maintaining oral hygiene is crucial for preventing AIDS progression.
A study found that parents with low income, limited education, and single status experience higher levels of stress, which increases the likelihood of their children developing tooth decay. Conversely, receiving treatment for a child's dental decay can decrease parental stress levels.
Researchers have made significant breakthroughs in salivary diagnostics, discovering new biomarkers for detecting oral cancer, acute coronary syndrome, and systemic diseases. The study highlights the potential of saliva as a non-invasive diagnostic tool, offering clear clinical advantages over traditional methods.
Dr. Anthony Fauci, director of NIAID, receives IADR Honorary Membership for his significant contributions to dental research. The award recognizes his commitment to improving oral health worldwide.
The International Association for Dental Research (IADR) has awarded C. E. Semino with the JDR Cover of the Year Award for his paper on self-assembling peptides and their potential in bone regeneration. The award recognizes aesthetically pleasing and scientifically novel images that enhance research impact.
Andreas Niklas, a University of Regensburg Medical School student, has won the prestigious fellowship for his proposal on developing an in vivo optical measurement device. The $2,500 prize is supported by an endowment created by late IADR President David B. Scott's wife.
The 2009 William J. Gies Awards recognize outstanding papers published in the Journal of Dental Research. The awards were presented to E. Scheller et al., S. Paris et al., and A.E. Sanders et al. for their work on Wnt/β-catenin, resin infiltration, and psychological stress mediation in tooth loss.
Dr. Fujio Miura receives the 2009 IADR Distinguished Service Award for his dedication to promoting JADR/IADR membership among young researchers in Japan, leading to significant growth in both Associations. The award recognizes his outstanding service and contributions to advancing dental research worldwide.
Dr. Mirela Shinohara, a young researcher from Brazil, has been awarded the 2009 Toshio Nakao Fellowship by IADR. The fellowship supports her training and experience in dental materials science at a center of excellence. IADR is a nonprofit organization dedicated to advancing research and improving oral health worldwide.
Congressman Mike Simpson has received an honorary membership from AADR for his long-standing support of the National Institutes of Health (NIH) and its impact on dental research. The recognition is a testament to his commitment to advancing oral health through research.
The International Association for Dental Research (IADR) has awarded Lars Petersson with the 2009 E.W. Borrow Memorial Award for his original research and achievements in promoting children's oral health. The award recognizes Petersson's work in advancing knowledge to improve oral health worldwide.
Roseann Mulligan, a University of Southern California researcher, has been recognized by AADR for her work improving oral health in vulnerable populations. She will receive the award at the International Association for Dental Research's General Session & Exhibition in Miami, Florida.
The International Association for Dental Research presented several awards, including the IADR Honorary Membership to Anthony Fauci, the IADR Distinguished Service Award to Fujio Miura, and the IADR/AADR William J. Gies Awards in various categories. The organization also recognized outstanding research achievements through the IADR E.W...
Dr. Athena Papas receives IADR's highest honor for her outstanding research on dry mouth, tooth sensitivity, and oral health in cancer patients. Her nearly 30-year career has secured over $20 million in grant funding.
Dr. Lior Shapira has received the IADR Basic Research in Periodontal Disease Award for his groundbreaking work on the mechanisms of inflammatory responses in periodontitis. He has published over 100 scientific articles and chapters, and continues to serve as a prominent figure in the field.
Dr. Cun-Yu Wang is recognized for his groundbreaking research in cancer therapy and oral health, with a focus on molecular signaling, inflammation, and adult human stem cells. He joins an elite group of scientists honored by IADR for their contributions to advancing oral health knowledge worldwide.
Dr. Jane Weintraub, a renowned oral epidemiologist, has been selected as the recipient of the International Association for Dental Research's H. Trendley Dean Memorial Award. She is being recognized for her groundbreaking research on children's oral health disparities and its impact on public health.
Dr. Graeme Hunter, a renowned dental researcher, has received the 2009 Biological Mineralization Award from the International Association for Dental Research (IADR). His work focuses on the physical biochemistry of biomineralization, with significant contributions to understanding mineralized tissues and pathological calcifications.
Dr. Philippe Hujoel, a professor at the University of Washington School of Dentistry, is recognized for his outstanding achievements in behavioral science and health services research. He has published over 70 peer-reviewed papers on periodontal disease processes and oral-healthrelated quality of life.
Professor Alessandro Riva, a leading expert in human exocrine glands, has made significant contributions to the understanding of salivary gland structure and function. He established benchmarks for the field through his published work, which includes numerous original observations and unique methods.