Microglia that express the APOE4 gene cannot metabolize lipids normally, leading to a buildup of excess lipids that interferes with nearby neurons' ability to communicate. Restoring normal lipid metabolism in microglia may help treat some symptoms of Alzheimer's disease.
Researchers developed a more sensitive approach to detect atomic-level structural damage in materials, enabling longer operational lifetimes for nuclear reactors. The new technique uses differential scanning calorimetry to measure energy changes within materials, revealing two mechanisms involved in radiation damage at elevated tempera...
Researchers at MIT have developed a machine-learning system that uses computer vision to monitor the 3D printing process and correct errors in real-time. The system successfully printed objects more accurately than other 3D printing controllers, enabling engineers to incorporate novel materials into their prints with ease.
Researchers developed a new printing technique that applies a 19th-century color photography method to modern holographic materials, producing large-scale images on elastic materials with structural color. The team's results enable the creation of pressure-monitoring bandages, shade-shifting fabrics, or touch-sensing robots.
MIT researchers have developed a new type of programmable resistor that enables analog deep learning, which promises faster computation with reduced energy usage. The device can process complex AI tasks like image recognition and natural language processing, paving the way for integration into commercial computing hardware.
The new ultrasound sticker uses a stretchy adhesive layer and rigid array of transducers to produce higher resolution images over a longer duration. It has potential applications in clinical diagnosis and could be made into wearable imaging products that patients can take home or buy at a pharmacy.
Researchers at MIT estimate the probability of getting Covid-19 on a plane flight was about 1 in 2,000 from June 2020 to February 2021. The study provides a general estimate of air travel safety with regard to Covid-19 transmission and a methodology that can be applied to future studies.
MIT scientists have developed 3D-printed plasma sensors that can be produced for tens of dollars in a matter of days, ideal for CubeSats. The sensors use a glass-ceramic material and can withstand wide temperature swings, measuring energy and conducting chemical analyses to predict weather or monitor climate change.
A new study from MIT and Broad Institute researchers analyzed interactions between nanoparticles and nearly 500 types of cancer cells, revealing thousands of biological traits that influence cell response. The findings could help tailor drug-delivery particles to specific types of cancer.
Cubic boron arsenide overcomes silicon's limitations, providing high electron and hole mobility and excellent thermal conductivity. The material has been shown to have a significant potential in various applications where its unique properties would make a difference.
Researchers at MIT develop a biodegradable system based on silk to replace microplastics added to agricultural products, paints, and cosmetics. The new material is made from widely available and less expensive silk protein, which can be dissolved using a scalable water-based process.
A study suggests that an automated unemployment insurance policy could provide more clarity to workers during economic stress. The policy would not cost more or less than existing packages, but would resolve uncertainty and potentially prevent household financial crises.
Developed a dataset of over 2,000 clinically relevant questions written by medical experts to train AI models. The model asked high-quality and authentic questions over 60% of the time, compared to real questions from medical experts.
Researchers have detected a persistent radio signal from a far-off galaxy that repeats every 0.2 seconds in a clear periodic pattern, similar to a heartbeat. The source of the signal is unknown but may be related to a radio pulsar or magnetar, which could provide an astrophysical clock for measuring the universe's expansion.
MIT researchers create microparticles that release their payload at different times, enabling self-boosting vaccines. The particles degrade over time and break down once released, allowing for potential use in regions with limited access to medical care.
Researchers developed smart textiles that sense wearer's posture and motions using a novel fabrication process called thermoforming, which improves pressure sensor precision. The technology has potential applications in healthcare and rehabilitation, such as tracking gait or monitoring pressure on diabetic patients' feet.
Researchers found the moon's crust was highly porous, about one-third as porous as pumice, due to massive impacts that shattered much of the crust. The team estimated the moon experienced double the number of impacts as seen on its surface, which limits constraints on solar system formation and evolution.
Researchers at MIT and Weizmann Institute of Science visualize electron vortices in ultraclean tungsten ditelluride, confirming theoretical predictions. The observation could lead to more efficient next-generation electronics by reducing energy dissipation.
The study reveals how the EGF receptor changes its shape when binding to its target, triggering cell growth and proliferation. The findings could lead to the design of new cancer drugs that evade resistance, says MIT chemist Gabriela Schlau-Cohen.
Researchers have devised a way to deliver carbon monoxide to the body using stable foams that can be delivered to the digestive tract. The foams reduced inflammation of the colon and helped reverse acute liver failure in mice, offering a potential alternative to immunosuppressive treatments.
A new robotic system, FuseBot, has been developed to efficiently retrieve buried objects in piles. The system uses radio frequency signals and computer vision to reason about the probable location and orientation of objects under the pile, enabling it to find more hidden items than a state-of-the-art robotics system in half the time.
Researchers at MIT have created a new liver tissue model that identifies one molecule playing a key role in human liver regeneration. The study also reveals several other candidates that will be explored further to discover new human-specific pathways.
Researchers at MIT have developed a method to enable quantum sensors to detect any arbitrary frequency without losing nanoscale spatial resolution. The new system, called a quantum mixer, injects a second frequency into the detector using microwaves, enabling detection of signals with desired frequencies.
Researchers at MIT created insect-scale robots that can emit light during flight, allowing for precise motion tracking and potential communication between robots. The ability to emit light also enables the robots to call for help in search-and-rescue missions.
A new optimization tool can quickly improve performance of various autonomous systems, including walking robots and self-driving vehicles. The tool uses automatic differentiation to identify tweaks that achieve desired outcomes, reducing trial-and-error simulations.
A new computer model has been developed to rapidly scan cancer genomes and identify harmful driver mutations that contribute to tumor growth. The model, trained on genomic data from various types of cancer, found additional mutations in 5-10% of patients that could help doctors identify more effective treatment options.
Scientists have discovered a new multiplanet system about 33 light-years from Earth, featuring two rocky, Earth-sized planets. The inner planet orbits every 2.8 days and is twice as massive as the Earth, while the outer planet orbits every 5.7 days and is three times as massive.
Asteroid Psyche's varied surface suggests a dynamic history, with metallic eruptions, asteroid-shaking impacts, and a lost rocky mantle. The new maps hint at the asteroid's ancient core, which could be composed of silicate-rich material that has since disappeared.
MIT researchers demonstrate two security methods that protect analog-to-digital converters from powerful attacks, including power and electromagnetic side-channel attacks. The techniques are more efficient and less expensive than other security methods, minimizing power consumption and cost for portable smart devices.
Researchers designed a modular AI chip that can be easily upgraded by swapping out layers, reducing the need for new devices. The chip uses optical communication to transmit information between layers, enabling high versatility in edge computing applications.
Researchers developed a nanoparticle sensor that can accurately distinguish between viral and bacterial pneumonia within two hours using a simple urine test. The sensor uses the host's immune response to infection, detecting specific protease patterns that serve as signatures of bacterial or viral infection.
Researchers at MIT identified a flawed analysis of website-fingerprinting attacks and developed new techniques to prevent them. They found that attackers can use machine-learning algorithms to decode signals leaked between software programs, enabling them to obtain private information.
Researchers have identified three distinct brain circuits in the thalamus that contribute to Parkinson's disease symptoms, including motor dysfunction and depression. By manipulating these circuits, they were able to reverse Parkinson's symptoms in mice, suggesting potential new therapeutic targets.
A study by MIT economists reveals that international trade widens income gap in individual countries, with Ecuador serving as a case study. The research shows that trade generates income gains primarily for those at the top and middle percentiles, exacerbating inequality.
PaSh parallelizes Unix shell scripts automatically and accurately, boosting execution speeds by hundreds of times. Researchers tested the system on hundreds of scripts and found no errors, making it accessible to data scientists, biologists, engineers, and economists.
A new study provides a roadmap for the US to reach its 50% greenhouse gas emissions reduction target by 2030, with rapid decarbonization in power and transportation sectors crucial. The study, based on six leading energy models, suggests that tripling historic carbon reductions is achievable through collaboration across all sectors.
Researchers have identified glycans in mucus that can prevent Candida albicans from causing infection. These molecules can be used to develop new antifungal medicines or make disease-causing fungus more susceptible to existing drugs.
Researchers have created prototypes that provide text descriptions at varying levels of detail, enabling blind and low-vision individuals to drill down from high-level data to more detailed information using just a few keystrokes. The prototypes improved users' ability to identify patterns in the data and navigate through visualization...
A study by MIT researchers found that sectarian identity in the Muslim world is often intertwined with local politics and shaped by social interactions. Domestic economic and political factors influence variation in sectarianism more than transnational matters do.
A team of MIT researchers has developed drug-carrying nanoparticles that can efficiently penetrate the brain and kill glioblastoma cells. Using a human tissue model, they showed that the particles could get into tumors and deliver chemotherapy drugs, including cisplatin, which effectively killed tumor cells.
A new MIT study finds that noradrenaline helps the brain learn from surprising outcomes by stimulating behavior that leads to a reward, particularly in uncertain situations. The researchers also discovered that noradrenaline promotes taking a chance on getting a reward, even when the outcome is unknown.
Researchers at MIT found that explanation methods used to aid human decision-makers in high-stakes situations often have lower accuracy for minoritized subgroups. The fidelity of these explanations varies dramatically between subgroups, with the quality often significantly lower for women and Black people.
The MIT team developed wavelength-induced frequency filtering (WIFF), a novel photonic technique that dramatically improves fluorescent sensor signals. This allows for the implantation of sensors as deep as 5.5 cm in tissue, enabling applications such as tracking specific molecules inside the brain or monitoring drug effects.
Researchers at MIT have designed a new type of photoredox catalyst that can be used to coat plastic tubing and perform chemical transformations on reactants as they flow through the tube. This breakthrough could enable the use of light-driven reactions in manufacturing processes, increasing efficiency and reducing waste.
Researchers created oil-based gels that can deliver a variety of medications, including those for infectious diseases, in a stable and palatable form. The gels can be used to administer drugs to children and adults with difficulty swallowing pills, and could have a significant impact on improving medication adherence.
MIT researchers develop an interactive design pipeline enabling users to create customized robotic hands with tactile sensors. The platform streamlines the process, allowing users to adjust palm and fingers and integrate tactile sensors, resulting in complex tasks like picking delicate items or using tools being performed flawlessly.
Lab-grown plant material can be precisely controlled for physical and mechanical properties, such as stiffness and density. The researchers use a 3D bioprinting process to grow custom shapes and sizes of plant material.
Researchers at MIT developed a technique that enables an autonomous vehicle to plot a provably safe trajectory in highly uncertain situations. The algorithm considers probability of observing different environmental conditions and obstacles, and formulates trajectory planning as a probabilistic optimization problem.
Scientists have found a novel pathway for forming smaller crystals in metals, leading to improved strength and toughness. By bombarding metal surfaces with tiny particles at high speeds, researchers increased copper's strength about tenfold.
Researchers have discovered that 90% of known crystalline structures contain at least one topological property, and more than 50% exhibit some sort of topological behavior. The newly identified materials are stored in a freely accessible database, allowing scientists to quickly search for materials with robust electronic properties.