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Northwestern University


New genetic path for scleroderma

A genetic pathway previously known for its role in embryonic development and cancer has been identified as a target for systemic sclerosis, or scleroderma, therapy. The finding reveals that the Wnt signaling pathway is abnormally activated in scleroderma patients, leading to fibrosis and tissue damage.

SourceNorthwestern University·JournalArthritis & Rheumatism·DateMar 19, 2012

Diagnosis of ADHD on the rise

The number of ADHD diagnoses among American children has increased by 66% over the past decade, according to a new study published in Academic Pediatrics. Specialists are now treating an increasing proportion of these young patients, shifting away from primary care physicians.

SourceNorthwestern University·JournalAcademic Pediatrics·DateMar 19, 2012

Who wouldn't pay a penny for a sports car?

In a study of hundreds of online auctions, Northwestern University researchers found that all participants use the optimal strategy, making the auction a game of pure chance. The 'bursty' strategy, which combines exploitation and exploration, is used by participants but ultimately leads to no advantage.

SourceNorthwestern University·JournalPLOS ONE·DateMar 16, 2012

Influencing stem cell fate

Scientists at Northwestern University developed a powerful analytical method called nanocombinatorics to rapidly identify the chemical and physical structures that cue stem cells to become osteocytes. The researchers successfully directed stem cell differentiation without additional chemical cues, demonstrating better control than curr...

SourceNorthwestern University·JournalProceedings of the National Academy of Sciences·DateMar 6, 2012

Energy squeeze

Researchers at Northwestern University discovered that squeezed polymers can generate significant amounts of energy for chemical reactions. However, they also found that certain polymer-based medical implants release harmful free radicals under moderate pressure, raising concerns about their safety.

SourceNorthwestern University·JournalAngewandte Chemie·DateMar 2, 2012

Heart healthy choices now pay off later

A Northwestern University study found that maintaining a healthy lifestyle from young adulthood into middle age can significantly reduce cardiovascular disease risk. Those who adhered to five key lifestyle factors, including a balanced diet and regular physical activity, were more likely to maintain a low-risk profile in their 40s.

Voters overrate favorite candidates

A new study from Northwestern University suggests that people consistently believe their preferred candidate will win an election, even if they're behind in the polls. The false consensus effect, a psychological phenomenon, is thought to be driving this trend.

SourceNorthwestern University·JournalProceedings of the National Academy of Sciences·DateFeb 23, 2012

A step toward better electronics

Researchers at Northwestern University have created a new method to oxidize graphene, overcoming the material's zero band-gap issue. The reversible oxidation process enables tunability of electronic properties, paving the way for high-performance applications.

SourceNorthwestern University·JournalNature Chemistry·DateFeb 19, 2012

What shields gay youth from suicide

Adolescents who feel supported by their families and have caring friends are less likely to consider ending their lives. Conversely, those who experience victimization due to being gay are at a higher risk of suicidal thoughts and self-harm behaviors.

SourceNorthwestern University·JournalAmerican Journal of Preventive Medicine·DateFeb 14, 2012

Cut your Valentine some slack

A Northwestern University study shows that perceiving a partner's efforts to improve the relationship enhances feelings of security and happiness. The research suggests that acknowledging a partner's capabilities for change is crucial to building a happy relationship.

SourceNorthwestern University·JournalPersonality and Social Psychology Bulletin·DateFeb 13, 2012

A therapist in your pocket

Researchers at Northwestern University are developing novel technologies to treat depression and other mood disorders using smartphones, web-based platforms, and virtual human coaches. These innovative approaches aim to provide immediate support, increase accessibility, and reduce costs.

Does online dating really work?

A new study by Northwestern University researchers found that ineffective algorithms and profiles hinder online dating. In contrast, mobile dating enables potential partners to meet face-to-face quickly, which is crucial for finding compatibility.

SourceNorthwestern University·JournalPsychological Science in the Public Interest·DateFeb 6, 2012

The secret life of proteins

A Northwestern University study identifies a key player in the human immune system, revealing its crucial role in activating the immune response. The protein, STIM1, was found to regulate not only one function but also another critical step in immune activation.

SourceNorthwestern University·JournalNature·DateJan 27, 2012

Will you have a heart attack or stroke?

A Northwestern University study reveals that individuals with low short-term risk may face very high lifetime risk of heart disease if they have just one or two risk factors, such as high cholesterol or blood pressure. The study found significant variations in risk by age, sex and race.

SourceNorthwestern University·JournalNew England Journal of Medicine·DateJan 25, 2012

Another clue in the mystery of autism

A new study published in Psychological Medicine found that low birth weight is an important environmental factor contributing to the risk of autism spectrum disorder (ASD). The researchers used a unique study design involving discordant twin pairs and found that lower birth weight more than tripled the risk for autism.

SourceNorthwestern University·JournalPsychological Medicine·DateJan 19, 2012

Girl power surges in India

A Northwestern University study shows that India's affirmative action law for village councils has a positive impact on young women's aspirations and behavior. The law gave girls direct role models, leading to increased attendance at school and reduced household chores, as well as improved attitudes toward higher education goals.

SourceNorthwestern University·JournalScience·DateJan 12, 2012

Tiny worm points to big promise

Researchers at Northwestern University identified nine core genes that protect cells from protein misfolding, a common cause of over 300 diseases. They also discovered seven classes of small molecules that restore proper protein folding and reduce disease progression.

3-dimensional view of 1-dimensional nanostructures

Researchers at Northwestern University have discovered that individual gallium nitride nanowires exhibit strong piezoelectricity in three dimensions, with efficiency up to six times greater than bulk material. This finding has significant implications for the development of nanogenerators capable of powering self-powered devices.

SourceNorthwestern University·JournalNano Letters·DateJan 5, 2012

You say you don't care about dating a hottie?

A new methodology developed by Northwestern University researchers reveals that people's implicit, split-second responses to physically attractive individuals better predict their attraction to them. This challenges the idea that stated preferences for partners accurately reflect one's true desires.

SourceNorthwestern University·JournalJournal of Personality and Social Psychology·DateJan 5, 2012

New predictor of heart attack or stroke

A new study from Northwestern University finds that a significant increase in blood pressure during middle age increases the risk of heart attack or stroke. Maintaining low blood pressure early on can reduce this risk, with those who keep their blood pressure low having a significantly lower risk.

Artificially enhanced athletes

A study from Northwestern University found that banned technical swimsuits played a significant role in the unprecedented number of world records set in swimming during the 2009 world championships. The suits were suspected of reducing drag, improving buoyancy, and compressing muscles, leading to enhanced performance.

SourceNorthwestern University·JournalThe Journal of Strength and Conditioning Research·DateDec 12, 2011

Great expectations

Researchers outline challenges and potential solutions for synthetic molecular machines to fulfill their promise. The team proposes using metal-organic frameworks to organize molecular switches spatially and temporally.

SourceNorthwestern University·JournalChemical Society Reviews·DateNov 25, 2011

On track to getting even fatter

According to Northwestern University researchers, over 83% of men and 72% of women will be overweight or obese in 2020. The implications of not improving cardiovascular health by 20% could lead to a reversal of declining rates of sickness and death from cardiovascular disease.

Better batteries

Researchers at Northwestern University have created an electrode that allows lithium-ion batteries to hold a charge up to 10 times greater than current technology. The new technology can also charge 10 times faster, paving the way for more efficient and smaller batteries for electric cars.

SourceNorthwestern University·JournalAdvanced Energy Materials·DateNov 14, 2011

More promising natural gas storage?

Researchers at Northwestern University have developed a computational method to quickly identify metal-organic frameworks (MOFs) with high potential for natural gas storage. The new algorithm rapidly generates and tests hypothetical MOFs, leading to the discovery of over 300 promising structures.

SourceNorthwestern University·JournalNature Chemistry·DateNov 6, 2011

Dead of winter is tough on arthritis sufferers

A Northwestern University study found that winter's shorter days and colder temperatures deter older Chicagoans with arthritis from engaging in daily physical activity. The lack of indoor recreational facilities for lower-income individuals exacerbates this issue, leading to serious health consequences.

SourceNorthwestern University·JournalJournal of Physical Activity and Health·DateNov 4, 2011

So many proteins, so much promise

A team at Northwestern University has developed a new method to identify thousands of protein molecules quickly, which could lead to the discovery of biomarkers and early disease detection. The approach, known as top-down proteomics, measures proteins intact instead of breaking them down into smaller parts.

SourceNorthwestern University·JournalNature·DateOct 30, 2011

Blue stragglers

Astronomers discover how blue stragglers, old stars appearing younger than expected, are created through mass transfer. The study reveals that these stars eat up the mass of their giant-star companion, allowing them to continue burning and living longer.

SourceNorthwestern University·JournalNature·DateOct 19, 2011

Nourishing protein slows brain disease

A protein that promotes neuron growth and blood vessel formation appears to halt brain degeneration in a genetic disease, according to Northwestern University research published in Nature Medicine. The study suggests a link between aging and the development of spinocerebellar ataxia type 1, a disease causing cerebellum degeneration.

SourceNorthwestern University·JournalNature Medicine·DateOct 17, 2011

Could a computer one day rewire itself?

Scientists at Northwestern University have developed a reconfigurable electronic material that can rearrange itself to meet different computational needs. This new material enables the creation of self-adapting electronic components with directed paths for electron flow.

SourceNorthwestern University·JournalNature Nanotechnology·DateOct 16, 2011

Lower income dads active in their kids' health

A study from Northwestern University found that lower-income urban dads are involved in their children's health and encourage exercise and healthy eating, but also face challenges in handling emergency medical care. Fathers reported modeling behavior for their kids, such as exercising and playing, to promote healthy habits.

SourceNorthwestern University·JournalPsychology of Men & Masculinity·DateOct 13, 2011

Emulating -- and surpassing -- nature

Researchers at Northwestern University have developed a method to build crystalline materials from nanoparticles and DNA, allowing for the creation of new materials with predictable physical properties. The design rules enable controlled crystallization, resulting in a variety of structures with unique properties.

SourceNorthwestern University·JournalScience·DateOct 13, 2011

Peanut allergy turned off by tricking immune system

Researchers have developed a method to create tolerance in the immune system by attaching peanut proteins onto blood cells and reintroducing them. This approach has shown promise in preventing life-threatening allergic reactions. By tricking the immune system, researchers hope to target multiple food allergies at once.

SourceNorthwestern University·JournalThe Journal of Immunology·DateOct 10, 2011

Sniffing out the brain's predictive power

A new study from Northwestern Medicine found that the brain uses predictive coding to generate templates of specific smells, setting up a mental expectation before sensing them. This ability provides humans with a behavioral advantage in reacting quickly and accurately to stimuli in their environment.

SourceNorthwestern University·JournalNeuron·DateOct 6, 2011