Scleroderma is a chronic autoimmune disease affecting 300,000 US citizens, causing skin thickening and internal organ damage. Researchers at Northwestern will identify biomarkers using proteomics to develop targeted therapies.
Researchers outline challenges and potential solutions for synthetic molecular machines to fulfill their promise. The team proposes using metal-organic frameworks to organize molecular switches spatially and temporally.
Researchers at Northwestern University have discovered a second faulty gene, sequestosome1, contributing to the degeneration of motor neurons in ALS. The study provides new insights into the disease's progression and potential targets for drug therapies.
According to Northwestern University researchers, over 83% of men and 72% of women will be overweight or obese in 2020. The implications of not improving cardiovascular health by 20% could lead to a reversal of declining rates of sickness and death from cardiovascular disease.
A new study reveals that US teens are at a higher risk of dying from heart disease due to high blood sugar levels, obesity, and poor diets. The research found that only zero children or adolescents met the criteria for ideal cardiovascular health.
New research from Northwestern University and Texas A&M University suggests that ideal partner preferences can be flexible once meeting in person. People tend to focus on the whole person rather than individual traits, making preconceived notions less important.
Researchers at Northwestern University have created an electrode that allows lithium-ion batteries to hold a charge up to 10 times greater than current technology. The new technology can also charge 10 times faster, paving the way for more efficient and smaller batteries for electric cars.
Researchers at Northwestern University have developed a computational method to quickly identify metal-organic frameworks (MOFs) with high potential for natural gas storage. The new algorithm rapidly generates and tests hypothetical MOFs, leading to the discovery of over 300 promising structures.
A Northwestern University study found that winter's shorter days and colder temperatures deter older Chicagoans with arthritis from engaging in daily physical activity. The lack of indoor recreational facilities for lower-income individuals exacerbates this issue, leading to serious health consequences.
Researchers at Northwestern University developed a new material that absorbs a wide range of wavelengths, enabling more efficient solar cells. The innovative trapezoid shape could be replicated in semiconducting materials to lead to thinner, lower-cost, and more efficient solar technology.
A team at Northwestern University has developed a new method to identify thousands of protein molecules quickly, which could lead to the discovery of biomarkers and early disease detection. The approach, known as top-down proteomics, measures proteins intact instead of breaking them down into smaller parts.
The new superlattice cameras can detect multiple infrared wavelengths simultaneously, enabling real-time chemical spectroscopy and enhanced image processing. These advancements offer unique functionalities beyond color representation, making them an attractive technology for various applications.
Astronomers discover how blue stragglers, old stars appearing younger than expected, are created through mass transfer. The study reveals that these stars eat up the mass of their giant-star companion, allowing them to continue burning and living longer.
A protein that promotes neuron growth and blood vessel formation appears to halt brain degeneration in a genetic disease, according to Northwestern University research published in Nature Medicine. The study suggests a link between aging and the development of spinocerebellar ataxia type 1, a disease causing cerebellum degeneration.
Scientists at Northwestern University have developed a reconfigurable electronic material that can rearrange itself to meet different computational needs. This new material enables the creation of self-adapting electronic components with directed paths for electron flow.
Researchers at Northwestern University have developed a new form of graphene that resists aggregation, thanks to its crumpled shape. The material retains its surface area and remains pure, making it more useful for applications requiring large amounts of the material.
A study from Northwestern University found that lower-income urban dads are involved in their children's health and encourage exercise and healthy eating, but also face challenges in handling emergency medical care. Fathers reported modeling behavior for their kids, such as exercising and playing, to promote healthy habits.
Researchers at Northwestern University have developed a method to build crystalline materials from nanoparticles and DNA, allowing for the creation of new materials with predictable physical properties. The design rules enable controlled crystallization, resulting in a variety of structures with unique properties.
Researchers have developed a method to create tolerance in the immune system by attaching peanut proteins onto blood cells and reintroducing them. This approach has shown promise in preventing life-threatening allergic reactions. By tricking the immune system, researchers hope to target multiple food allergies at once.
A new study from Northwestern Medicine found that the brain uses predictive coding to generate templates of specific smells, setting up a mental expectation before sensing them. This ability provides humans with a behavioral advantage in reacting quickly and accurately to stimuli in their environment.
Researchers have successfully generated high-power, narrowband terahertz radiation at room temperature using a single semiconductor chip. This breakthrough could enable rapid security screening, border protection, high-sensitivity biological/chemical analysis, and astronomical applications.
A new study explains why leaders are often perceived as strong and dominant, despite their generosity. In non-competitive contexts, generous individuals are admired and respected, but in times of competition, they are seen as weak and submissive.
A new Northwestern University study found that adolescents in mixed friend groups were insulated from the influence of peers who were delinquent or low-academic achievers. Neighborhood violence and territorial boundaries constrained their friendship choices.
A new material made of carbon nanotubes provides a cost-efficient alternative to current technology, boosting the long-term viability of solar power. The material's mechanical flexibility enables integration into fabrics and clothing, paving the way for portable energy supplies.
Researchers at Northwestern University have discovered edible compounds that efficiently detect, capture and store carbon dioxide. The porous crystals, made from sugar, salt and alcohol, are simple to prepare and turn red when full of CO2.
Researchers found that bortezomib inhibits transforming growth factor beta, a protein essential for scar tissue growth, preventing its development in human cells and mouse models. The drug also prevented expression of proteins necessary for scarring in fibroblast cells from scleroderma patients
African-American men are up to 3.5 times more likely to have Vitamin D deficiency than Caucasian men, requiring higher supplementation doses. Skin color and sunlight exposure play a crucial role in Vitamin D production.
Researchers developed semiconductor materials that detect gamma rays, identifying plutonium and uranium. The method uses dimensional reduction to create heavy elements with immobilized electrons, making them suitable for detection.
A new Northwestern University study confirms that human males are biologically wired to care for their offspring, showing that fatherhood significantly lowers testosterone levels. The study found that fathers who became more involved in child care experienced the largest decline in testosterone.
The Materials Research Science and Engineering Center at Northwestern University has received a six-year, $16.2 million grant to support its interdisciplinary research program and educational activities. The center aims to develop new nanoscale materials with applications in information processing, electronics, and sensing technologies.
Researchers at Northwestern University have discovered a new protein called P21, which acts as a protective barrier against hyperactive immune cells in people with rheumatoid arthritis. By inhibiting the immune cells' destructive rampage, the bouncer molecule halts the disease process, offering a promising new avenue for future therapies.
Researchers at Northwestern University have developed a new model for predicting disease spread by considering the base location of individuals. This approach creates significant differences in disease predictions compared to traditional models.
Scientists identify genetic differences between mild and deadly Plague bacteria, revealing the role of small non-coding RNAs in disease severity. The study provides new insights into the evolution of pathogens and potential therapeutic targets for deadly diseases like the Plague.
Researchers found that a genetic switch in master neurons inhibits the proper functioning of protective cell stress responses, accumulating misfolded and damaged proteins. Restoring this natural ability could offer a new target for therapy, improving cellular health and quality of life.
Scientists have discovered a common cause of all forms of ALS, a fatal neurodegenerative disease, by identifying a broken down protein recycling system in neurons. This finding provides a common target for drug therapy and suggests that all types of ALS are tributaries pouring into a common river of cellular incompetence.
Researchers will use genome-wide association studies to identify genetic variants associated with diseases, enabling the adjustment of patient medications and prevention of diseases. The eMERGE network has already identified genetic variants linked to dementia, cataracts, type 2 diabetes, and more.
A new study from Northwestern University finds that Chicago's south and southwest sides suffer the most in terms of residents' health and access to basic health resources. The study highlights significant disparities in healthcare access, including limited mammogram screening and HIV testing sites.
A Northwestern University study reveals that people with arthritis are not engaging in physical activity critical to their health. The research found that more than half of women and 40 percent of men with arthritis were inactive.
A novel nanostructure mimics vascular endothelial growth factor to promote blood vessel growth, potentially treating conditions like peripheral arterial disease. The nanostructure shows promise in restoring blood flow and has a longer half-life compared to the natural protein, enhancing its potency.
Researchers from Northwestern University have discovered a brain chemical, Substance P, that causes abnormal bone growth in injured muscles. This discovery offers a potential molecular target for preventing and treating heterotopic ossification.
A study published in the Journal of Adolescent Health found that teenagers with high positive well-being had reduced risk of engaging in unhealthy behaviors and reported excellent health in young adulthood. Positive psychological characteristics during adolescence are linked to improved long-term health outcomes.
A Northwestern University meta-analysis reveals that leadership continues to be viewed as culturally masculine, perpetuating barriers to women's advancement. The study finds that women are seen as less qualified or natural in leadership roles, and adopting masculine behaviors can lead to being viewed as inappropriate.
Research from Northwestern University found that 50% of college drinkers report at least one alcohol-induced memory blackout in the past year. Students who experienced these blackouts were more likely to suffer alcohol-related injuries, highlighting the need for better screening and interventions.
A phase II clinical trial found that injections of adult patients' own CD34+ stem cells reduced angina episodes and improved exercise tolerance time. The treatment showed significant improvements in chest pain and exercise duration at six months after treatment.
Scientists discovered that brain activity increases when viewing same-race and other-race faces, but only predicts whether an other-race face will be remembered. The study suggests that individuation process is fragile for other-race faces due to lack of practice and social categorization.
A new Northwestern Medicine study finds that attending physicians in intensive care units can reduce mortality rates by 50% when using a checklist and prompted to address overlooked details. The prompting system cut ventilator-associated pneumonia cases and reduced ICU length of stay.
Researchers at Northwestern University recreated ancient copper artifact-making techniques using large stones, fire, and elbow grease. They analyzed discarded copper pieces found on the ground of a 'copper workshop house' in Cahokia and determined that coppersmiths likely hammered and heated copper to create thin sheets.
Researchers at Northwestern University recreated ancient copper artifact-making techniques used by prehistoric Native Americans of Cahokia. They analyzed small pieces of discarded copper and determined that the coppersmiths likely hammered the copper with a heavy rock, then heated it in a wood fire to create thin sheets.
The study found significant racial disparities in children's media use, with minority youth spending an average of 13 hours per day on media compared to 9.5 hours for their white counterparts. Minority youth also tend to watch more TV and listen to music, while Asian youth spend more time playing video games and using computers.
A Northwestern University study found that cancer survivors experience moderate to severe symptoms such as pain, fatigue, and disturbed sleep, often unaddressed by healthcare providers. Researchers emphasize the need for education programs and tailored interventions to manage these chronic symptoms.