Researchers found that surgery in addition to treatments like chemotherapy and radiation therapy increased the length of survival for stage four breast cancer patients. The study, published in Annals of Surgical Oncology, suggests that knowing a cancer's biological subtype can help determine effective treatment plans.
Researchers found that surgery in addition to treatments like chemotherapy and radiation therapy increased survival for stage four breast cancer patients. Patients with hormone receptor-positive tumors saw a prolonged length of survival when their treatment plan included surgery.
Researchers found that deep, slow-slip behaviors beneath subduction zones, such as Cascadia, may control the timing and behavior of megathrust earthquakes. Slow-slip events, which occur at a deeper depth than damaging earthquakes, release energy in different directions, primarily down.
Researchers found that reduced amounts of p120ctn contribute to resistance in cancers with high EGFR levels, leading to poorer treatment outcomes. Testing for p120ctn levels may help clinicians identify patients at risk for therapy resistance or relapse.
Research led by Penn State scientists found that bumble bees in low-quality landscapes had higher levels of disease pathogens. The study's findings can inform management practices to support the conservation of wild bee populations and highlight the importance of maintaining high-quality habitats.
Researchers found that fibrous proteins form a solid layer on water's surface, interfering with fluid property measurements. This finding has the potential to improve bioprinting results by identifying optimal protein solution concentrations and operating parameters.
A team of Penn State engineers found a connection between nitric oxide-expressing neurons and changes in arterial diameters in mice, shedding light on brain function and aging. The researchers discovered that approximately half of the dynamic range in blood vessel diameter is controlled by a small group of neurons.
Researchers at Penn State have created multilayered quantum anomalous Hall (QAH) insulators, enabling the realization of the QAH effect over a broader range of conditions. This allows for the construction of high-speed electronic highways with minimal energy loss, which could significantly improve information transfer speed.
Researchers found that a small percentage of locations and events contribute to the majority of annual pollution loads entering the bay. The study suggests targeting 'hot moments' -- not just 'hot spots' -- across impaired watersheds to achieve water-quality-restoration goals.
Researchers at Penn State have developed a nanomaterial cement mixture that can effectively seal leaky natural gas wells, reducing methane emissions. The new cement is more resistant to cracking and can be pumped through narrow spaces, making it suitable for use in active unconventional wells and orphaned abandoned gas wells.
Researchers have discovered a new toxin-antitoxin system that allows bacteria to slow down their activity and thrive during periods of scarcity. The HEPN/MNT system, the most abundant TA system in prokaryotes, enables bacteria to conserve energy and resources by inhibiting toxin production.
A preschool enrichment program, REDI, has been shown to boost social and emotional skills that still have positive effects years later. Children attending Head Start preschools with the REDI program were less likely to experience behavioral problems and emotional symptoms by seventh and ninth grade.
Penn State researchers have created an automated process planning software to optimize additive manufacturing, reducing design time and material waste. The software uses algorithmic mapping of designs from CAD software to AM to minimize unnecessary steps, enabling faster production and lower costs.
Penn State researchers computationally modeled the attachment of SARS-CoV-2 protein spike to ACE2, finding it highly optimized for human binding. The team also explored changes in the virus spike that could alter its affinity with human ACE2, potentially informing future research on vaccine durability and animal transmission.
Researchers at Penn State have developed a new system that can harvest energy from human breathing and motion to power wearable health-monitoring devices. The system uses stretchable micro-supercapacitors with an island-bridge design, allowing it to stretch up to 100% without losing its functionality.
An international team of researchers has connected specific genetic signals with specific areas of the face, identifying 203 genomic regions that play a role in human facial development. The study sheds light on craniofacial malformations such as cleft lip and palate, as well as evolutionary differences between various populations.
Research found that neutrophils, a type of white blood cell, cause tissue death in brain cancer tissues, leading to poor survival rates for glioblastoma patients. The study identified ferroptosis as the underlying mechanism, which promotes tumor growth.
A Penn State research team conducted field tests on three commonly used mineral-based aerosol sunscreens, finding trace nanoparticles but at safe levels. The study suggests that the canister design and active ingredients are unlikely to produce vastly different amounts of nanoparticles.
A recent study found that pallets are responsible for over 30,000 hospital emergency room visits in the US due to unintentional contact. The majority of injured individuals were between 35-44 years old, with children under 18 and elderly people also at risk.
Researchers analyzed data from nearly half a million cancer patients in the US between 15-39 years old to determine cancer cases in this age group. The results show a 30% rise in cancer diagnoses among adolescents and young adults, with kidney, thyroid, and gastrointestinal cancers increasing at the greatest rates.
A study by Penn State researchers found that cultural factors significantly impact gesture choices, with some gestures differing between American and Chinese participants. The team identified common ground among cultures for similar purposes and actions.
Researchers used statistical analysis of zircon ages to determine continental formation timelines. The study suggests that modern-scale watersheds formed as early as 2.7 billion years ago.
Researchers at Penn State and the University of Michigan have developed an inexpensive therapy to prevent antibiotic resistance. The 'anti-antibiotic', cholestyramine, reduces fecal shedding of daptomycin-resistant bacteria by up to 80-fold, providing a potential solution to the growing problem of antimicrobial resistance.
Two genes involved in plumage coloration have evolved through distinct processes: ASIP, which produces melanin, and BCO2, which produces carotenoid pigments. The researchers found evidence of introgression, where genes from one species were transferred to another, contributing to the warblers' diverse colors.
A new study led by Penn State researchers found a link between the number of times a person gives birth and their physical aging process. The study discovered that people who had few or many births showed signs of quicker biological aging compared to those who had given birth three or four times. The effects were only visible after men...
A new study found that consuming dried fruit is linked to better diet quality and health markers, including lower body mass index and waist circumference. However, it's essential to choose unsweetened versions and monitor portion sizes due to the higher calorie content.
A Penn State researcher will study whether vitamin D supplementation can help people ward off or reduce symptoms caused by COVID-19. The research aims to determine the effects of vitamin D on SARS-CoV-2 infection and inflammation in the lung and gastrointestinal tract.
Researchers at Penn State created functional membraneless 'protocells' from short polymers that can sequester RNA and maintain distinct internal microenvironments. The protocells were stable in various salt concentrations and performed certain functions of a protocell, suggesting they could be relevant models for early life on Earth.
A genetic mutation in the 'coat' of a brain infection-causing virus may allow it to escape neutralizing antibodies, increasing the risk of developing a fatal brain disease. Researchers have identified this mutation in the mouse equivalent of JC polyomavirus and found that it prevents monoclonal antibodies from interacting with the virus.
African elephants in Tanzania show limited gene flow between protected areas, highlighting the importance of preserving wildlife corridors for conservation. The study found that some areas, like Lake Manyara and Ngorongoro Conservation Area, were once connected but now have limited genetic exchange.
A team of researchers from Penn State describes a system where oil droplets exhibit 'non-reciprocal' interactions, chasing down other droplets that flee like prey. The system is controlled by chemical signaling and can be tuned to understand interactions in many-body systems.
A recent study published in Medical Cannabis and Cannabinoids found that CBD oils are equally or less effective than pure CBD at inhibiting the growth of certain cancer cells. The researchers tested different types of CBD oil against pure CBD on various cancer cell lines, including brain, skin, and colorectal cancers.
Researchers at Penn State discovered that biochars made from cotton gin waste and guayule bagasse can adsorb pharmaceutical compounds, including sulfapyridine, docusate, and erythromycin. The study found that temperature increases during the pyrolysis process enhanced the biochar's capacity to adsorb contaminants.
A study found that dairy cows exposed to contaminated water carried more pathogens with antimicrobial-resistance genes, which can tolerate various antibiotics. The research highlights a threat to human health and supports the World Health Organization's declaration of antimicrobial resistance as a global public health threat.
A virtual reality forest created by geographers can let people walk through a simulated forest of today and see potential future scenarios. The researchers used data on a typical Wisconsin forest to create a more organic, natural feel, allowing visitors to experience the changes brought on by climate change.
Researchers developed an implantable smart wrap that detects when the bladder needs to be emptied and sends a signal to expand or contract. The device addresses the under-active bladder condition, where patients have difficulty urinating regularly.
Researchers found that self-reports of smell and taste changes were better correlated with COVID-19 hospital admissions than current governmental indicators. Smell/taste changes peaked four days after lockdown measures, while hospital indicator peaked 11 days later.
Premium chocolate consumers prioritize gold foil, ornate labels, and intriguing backstories. Craft chocolate is perceived as exclusive and special, with a focus on packaging, sustainability labels, and storytelling. Consumers value high-quality ingredients and unique experiences.
Research from Penn State Clinical and Translational Science Institute finds significant increases in diseases of despair diagnoses, including alcohol-, substance-, and suicide-related disorders. The rates increased by 37%, 94%, and 170% between 2007 and 2018, with the most substantial percentage increase among men ages 35 to 74.
Researchers warn that SARS-CoV-2 may develop resistance to COVID-19 vaccines, rendering them ineffective. To mitigate this risk, the team recommends using blood and nasal swab samples to assess vaccine efficacy and monitor for emerging resistance.
Researchers have designed a highly sensitive implantable sensor that can monitor various forms of nitric oxide and nitrogen dioxide in the body. The device is made from biodegradable materials, including magnesium and silicon, which dissolve at a slow pace allowing it to function during recovery periods.
Researchers analyzed saliva samples from over 500 participants to identify microRNA levels that could indicate a concussion. The study found that measuring these molecules in saliva can aid diagnosis with high accuracy, potentially replacing current symptom scales and neurocognitive tests.
New Penn State research reveals disparities in physical activity between men and women, with women more likely to feel uncomfortable using campus recreation facilities. The study suggests that design changes, social environments, and policies can help create welcoming spaces for all students.
A team of researchers has developed a model for acid-tolerant yeast that can produce succinic acid, a precursor for industrial polymer production. The model uses gene editing and computational tools to identify the optimal genetic modifications required to maximize succinic acid production.
Researchers at Penn State have developed an ultra-thin and energy-efficient photodetector on glass, paving the way for commercialization of 'smart glass' technology. The technology can be applied in various industries, including manufacturing, transportation, and healthcare.
A new study from Penn State reveals how fake news detectors can be manipulated through user comments, allowing adversaries to influence the detector's assessment of a story. The researchers developed a framework called Malcom to generate and optimize malicious comments that fool leading fake news detectors over 93% of the time.
A new study by Penn State researcher David Vanness found a cost-effectiveness threshold of $104,000 per QALY for health treatments. Beyond this point, the treatment may not be beneficial for population health due to increased costs and decreased quality-adjusted life-years.
Researchers at Penn State have developed graphene-based memory resistors that mimic the brain's neural networks and offer high precision neuromorphic computing. The new technology can control up to 16 possible memory states, compared to two in most existing memristors.
A new rapid diagnostic system for sepsis is being developed at Penn State and Stanford University, which can identify fungal and bacterial pathogens within two hours. The five-year grant will allow researchers to bypass current blood culture steps and directly test pathogen susceptibility to antibiotics.
A study by researchers at Penn State found that mulch bags labeled as 'cypress' often contain less than claimed, with some bags containing no cypress at all. The investigation used a new method to sort and estimate species mix in the mulch, revealing significant discrepancies between advertised content and actual composition.