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T. rex was a champion walker, super-efficient at lower speeds

Research finds giant T. rex relied on low-energy walking due to their massive size, contrary to previous focus on running speeds for theropod dinosaurs. The study analyzed limb proportions, body mass, and gaits of over 70 species, suggesting a trade-off between speed and efficiency in theropods.

SourcePLOS·JournalPLOS ONE·DateMay 13, 2020

New insights into links between national income and obesity

Analysis of data from 147 countries found a strong association between rising incomes and increasing obesity rates, with an average increase in obesity rates for every 1% rise in GDP per capita. The study suggests that policy initiatives may be necessary to combat obesity in low- and middle-income countries undergoing income growth.

SourcePLOS·JournalPLOS ONE·DateMay 13, 2020

How the brain responds to the sudden sound of silent danger

A novel neural circuit has been discovered in rats that responds to the sound of silence, triggering defense responses. The study found that a specific combination of brain regions, including those involved in sound processing and emotional responses, are necessary for rats to freeze in response to silent danger.

SourcePLOS·JournalPLOS Biology·DateMay 12, 2020

COPD and smoking associated with higher COVID-19 mortality

A new study has found that people with chronic obstructive pulmonary disease (COPD) and smokers are at a higher risk of severe complications and mortality from COVID-19. Researchers analyzed data from over 2,500 patients with COVID-19 and found that COPD was associated with a 63% risk of severe disease and a 60% risk of mortality.

SourcePLOS·JournalPLOS ONE·DateMay 11, 2020

Defining geographic regions with commuter data

Researchers developed a new method to define metropolitan areas based on census commuter data, identifying 182 clusters that account for over 90% of commuters. These clusters are larger than traditional regional definitions, suggesting important connections extending beyond expected boundaries.

SourcePLOS·JournalPLOS ONE·DateApr 30, 2020

Two COVID-19 papers published in PLOS ONE

Two PLOS ONE studies use the SIRD model to forecast COVID-19 spread and examine patient CT scans for clinical features with mortality. The models predict a significant number of infections (45,000+ in Hubei) and deaths (2,700+) by February 29. In contrast, patients with severe lung features were more likely to die from the virus.

SourcePLOS·JournalPLOS ONE·DateMar 31, 2020

Heat takes its toll on mental health

A study published in PLOS ONE found that hotter temperatures increase the probability of reporting bad mental health in the US. People are willing to pay several dollars to avoid each additional hot day in terms of its impact on self-reported mental health.

SourcePLOS·JournalPLOS ONE·DateMar 25, 2020

Engineered botox is more potent and safer in mice

A new study engineered a form of botulinum toxin B with improved binding to nerve cells, increasing potency and reducing diffusion into surrounding tissue. The modified toxin demonstrated enhanced therapeutic potential and reduced adverse effects.

SourcePLOS·JournalPLOS Biology·DateMar 17, 2020

Cellular stress makes obese mothers have obese babies

A new study reveals that maternal obesity triggers cellular stress in the endoplasmic reticulum, disrupting hypothalamic development and leading to offspring obesity. Bile acid treatment mitigates these changes, reversing obesity-related metabolic issues in mice offspring.

SourcePLOS·JournalPLOS Biology·DateMar 13, 2020

Flexible 'heroes' save delicate proteins from stress

A new class of proteins, dubbed 'Hero', has been discovered that protects vulnerable proteins from aggregation and denaturation under extreme heat and other stresses. These flexible proteins may help prevent neurodegenerative diseases such as ALS and Huntington's disease by preserving molecular order.

SourcePLOS·JournalPLOS Biology·DateMar 13, 2020

Divorced parents may impact some teens' academics

A study found that adolescents with divorced parents have lower GPAs, especially those with more educated mothers. The researchers controlled for paternal education and income measures, revealing a stronger association between divorce and reduced GPA among teens with highly educated mothers.

SourcePLOS·JournalPLOS ONE·DateMar 4, 2020

A PLOS Medicine special issue devoted to refugee and migrant health

A recent study on Rohingya refugees in Bangladesh found that 64% had significant physical disabilities, while caregivers reported providing over 13 hours of care per day. Another study in the UK found that migrant mothers were less likely to visit emergency departments with their children, but those who did had higher utilization rates.

SourcePLOS·JournalPLOS Medicine·DateMar 3, 2020

Jellyfish help understand the timing of egg production

A new study in PLOS Biology identifies a regulator of jellyfish egg release, shedding light on the evolution of complex hormonal control in animals. The discovery sheds insight into how oocytes transform into eggs and may hold clues for understanding the link between sexual reproduction and nutrition in animals.

SourcePLOS·JournalPLOS Biology·DateMar 3, 2020

Male-killing bacteria linked to butterfly color changes

A recent study found that a bacterium specifically kills male African monarch butterflies, leading to highly variable warning patterns. The researchers discovered that the bacterium's interaction with the female butterflies' unique chromosome arrangement causes this variability.

SourcePLOS·JournalPLOS Biology·DateFeb 28, 2020

Improving assessments of an endangered lion population in India

A new study provides alternative method for monitoring endangered lions, estimating an overall density of 8.53 lions per 100 square kilometers. The researchers found that prey density does not influence variations in lion density within the study site, and baiting lions for tourism perturbs their natural density patterns.

SourcePLOS·JournalPLOS ONE·DateFeb 19, 2020

Fish in the Sahara? Yes, in the early Holocene

A study published in PLOS ONE reveals the ancient hydrographic network of the Sahara, showing significant changes in climate and fauna over time. The Takarkori rock shelter, excavated by researchers, yielded fish remains that decreased in abundance as the region became more arid, replaced by mammal-heavy diet.

SourcePLOS·JournalPLOS ONE·DateFeb 19, 2020