Researchers at TUM discovered a mechanism that enables double-stranded RNA molecules to form and remain stable in the primordial soup. This discovery has significant implications for understanding the origin of life and could lead to breakthroughs in medicine, particularly in vaccine development.
Researchers at TUM have mapped the interactions of 144 active substances with around 8,000 proteins using a new method called decryptE. This study could help identify previously unknown potential benefits of existing drugs and improve treatment outcomes for patients.
The Technical University of Munich (TUM) has established a flagship partnership with Nanyang Technological University Singapore (NTU), expanding its global presence in the region. The partnership aims to tackle major challenges in Southeast Asia through collaboration on quantum sovereignty, artificial intelligence, and other key areas.
A study found that large language models, despite accuracy in medical exams, fail to consistently request necessary examinations and often deviate from treatment guidelines. In comparison to human doctors, AI diagnoses achieved lower accuracy rates, highlighting concerns about their suitability for everyday clinical practice.
A team of researchers has discovered a mechanism by which the liver's immune cells are suppressed in chronic hepatitis B, leading to organ damage. The 'sleep timer' function allows immune cells to weaken their activity over time, preventing them from proliferating excessively and causing further damage.
A recent study by Prof. Martin Bichler suggests that dividing Germany into several price zones may not reduce total power costs as expected. In contrast, nodal pricing shows promise in reducing costs by up to 9% due to efficient resource allocation and reduced re-dispatch measures.
A study by TUM researchers discovered four subtypes of Amyotrophic Lateral Sclerosis (ALS) with different molecular processes, including sex differences. The findings suggest repurposing an approved cancer drug targeting the MAPK pathway as a promising therapeutic approach for ALS.
Scientists at TUM develop advanced early detection method to predict abrupt shifts in natural systems. The new approach enhances ability to monitor and respond to potential tipping points, potentially anticipating large-scale climate events.
A study by Technical University of Munich found that Russian social media campaigns had a limited impact on the European public, with most people believing the disinformation being spread. The decisive factor in efficacy was whether a person is fundamentally receptive to conspiracy narratives.
A study at TUM has debunked the assumption that people overestimate dramatic causes of death due to media attention. Instead, deaths in personal environments have a more significant impact on risk perception. Respondents can consciously engage with news reports and incorporate other sources into their judgment.
A recent study by TUM, University of Jena, and Vienna University of Technology shows that city residents generally accept most animal species in urban environments. The majority of birds, mammals, arthropods, lizards, and frogs are popular, while cockroaches, rats, wasps, slugs, and pigeons are less liked. Urban planning can balance hu...
Researchers at TUM have uncovered a mechanism by which tumor cells prevent the formation of immune responses, including cytotoxic T cells. This discovery provides rationales for new cancer immunotherapies and could enhance existing treatments.
A research team at TUM and University of Hohenheim developed a promising approach to reconciling biodiversity conservation with agricultural productivity. Hybrid intelligence leverages collective human judgment and artificial intelligence to simulate biodiversity measures and support joint decision-making.
Researchers are developing a satellite-based quantum light source for secure communication, leveraging the laws of physics to encode and transmit data. The technology has the potential to extend quantum cryptography over long distances, enabling secure communications between cities or continents.
Researchers have discovered a previously unknown mechanism behind immune tolerance, where B cells teach T cells to ignore the body's own proteins. This failure can lead to autoimmune diseases such as Multiple Sclerosis-like Neuromyelitis optica.
A new study warns that climate change could reduce global wheat production by 13% by 2050 due to the spread of the fungal disease wheat blast. The affected regions will include South America, southern Africa and Asia, where up to 75% of total wheat acreage could be at risk.
Researchers found that specific microbes in the gut reduce graft versus host disease after stem cell transplantation. Patients with low microbial metabolite risk index had better survival rates, fewer graft vs. host reactions, and reduced relapses.
Researchers developed a method to measure microvascular changes in the skin using AI and optoacoustic imaging technology, enabling non-invasive assessment of diabetes severity. The study identified 32 significant changes in blood vessels, which can be used to monitor disease progression.
Researchers have decoded the factor driving rapid growth of T cell lymphomas, revealing a 'sugar appetite' that triggers processes leading to tumor growth. The discovery provides new hope for treating aggressive cancer types, with existing medications potentially effective against these tumors.
A simulation study suggests that a soft drink tax in Germany would reduce sugar consumption and illness rates, including type 2 diabetes, resulting in significant financial savings. The estimated economic benefits of introducing such a tax range from 9.5 billion to 16 billion euros over the next two decades.
Researchers found that changing treatment can lead to significant improvement in mobility and quality of life for patients with advanced Parkinson's disease. A nationwide registry is planned to develop scientifically sound guidelines for combination therapies.
The new AI chip uses ferroelectric transistors to store data and perform calculations, achieving a TOPS/W ratio of 885, twice as powerful as comparable chips. The goal is to use the chip for real-time applications such as deep learning and robotics, but security requirements and industry-specific criteria may delay its adoption.
Researchers developed diamond quantum sensors to improve resolution in magnetic imaging, enabling detailed visualization of microstructures within cells. The sensors can detect water molecules and explore ion diffusion, with potential applications in battery development and medical research.
Researchers at Technical University of Munich have developed a new class of organic dyes that can facilitate faster transport of solar energy within materials. These 'turbocharger' dyes show great promise for improving the efficiency of organic solar cells and other innovative energy applications.
A study at the Technical University of Munich found that people with long Covid experience altered blood vessels in the eye, which could be used to diagnose the condition. Persistent inflammatory responses were also linked to symptom severity and chronic inflammation.
A ban on personalized ads significantly reduces the number of available apps and updates, according to a TUM study. The findings can help policymakers and companies define their business models and adapt to regulations.
Researchers at TUM develop an RNA agent for a lung spray that slows macrophage activity, reducing lung inflammation and fibrosis. The active substance RCS-21 is delivered via an inhaler through a special sugar molecule, showing promise in treating acute inflammatory lung damage.
Researchers at Technical University of Munich have developed an automated analysis method for identifying and quantifying microplastics. The new process uses Raman microspectroscopy to analyze plastic particles directly, allowing for quick and reliable detection of their size, shape, and composition.
A study published in Science reveals that ganglia in the neck region are responsible for disrupting melatonin production and causing sleep disturbances in people with heart conditions. Researchers found that macrophages accumulate in the ganglion, leading to inflammation and scarring, which can be treated with drugs.
A study by Technical University of Munich (TUM) has identified numerous previously undetected methane sources in Hamburg, including leaking gas pipelines and incomplete combustion. The researchers used mobile measurements and sensor networks to detect unknown emissions and quantify their impact on greenhouse gas emissions.
A large-scale study found that exercise programs for dialysis patients lead to significant improvements in physical fitness, quality of life, and reduced hospital stays. Personalized exercise plans showed low costs per training unit, making them a viable option for standard healthcare coverage.
Researchers at Technical University of Munich have discovered that the outer envelope membrane of chloroplasts plays a crucial role in regulating metabolite transport, which is essential for optimizing photosynthesis. By understanding this process, scientists hope to develop new strategies to boost crop yields and produce more biomass.
Researchers at TUM developed a new approach to measure human brain activity using microelectrodes and awake brain surgery. They found individual neurons specialize in handling specific numbers, providing insights into cognitive functions and developing solutions for brain function disorders.
A new algorithm developed by a Munich research team can predict the effects of genetic mutations on RNA formation six times more precisely than previous models. The model focuses on splicing, a process that is thought to be one of the most common causes of incorrect protein formation and hereditary diseases.
Researchers at TUM have successfully developed a method to produce the essential amino acid L-alanine from CO2 using synthetic enzymes and green methanol. This process requires significantly less space than traditional methods and can be powered by renewable energy sources, making it an important step towards more sustainable agriculture.
Scientists at TUM create genetic reporter proteins that can be resolved by electron microscopy, unveiling invisible cellular structures and processes. The discovery enables further research into disease mechanisms and potential therapeutic cell production.
Researchers at TUM have developed a method to create mini-hearts in Petri dishes using stem cells. The resulting organoids mimic the earliest stages of human heart development and can be used to investigate congenital heart defects, potentially leading to new treatment methods.
Scientists create nanomaterial that mimics photosynthesis to produce syngas from carbon dioxide and water in the presence of sunlight. This innovation has potential for large-scale chemical industry applications and could lead to sustainable battery production.
A study by researchers at TUM found that gut bacteria play a crucial role in liver regeneration. The microbiome produces short-chain fatty acids, which are essential for liver cell growth and division. In mice treated with antibiotics, liver regeneration was delayed or not possible, but a
Researchers developed an ethical algorithm to distribute risk fairly in autonomous vehicles, considering multiple factors such as responsibility and traffic regulations. The new approach enables more nuanced decision-making in critical situations, weighing risks and avoiding aggressive maneuvers.
MIRMI researchers create robotic waiter with precise control using the principles of a spherical pendulum, achieving 'slosh-free movement' and improving safety. The solution has potential applications in healthcare and hazardous materials transport.
Scientists measure antihelium nuclei survival rate at ALICE experiment, laying foundation for dark matter search. Galaxy found to be 50% permeable for antinuclei, with implications for future experiments and search for antimatter in space.
Researchers have developed a new X-ray technology that visualizes lung tissue microstructure, providing additional information for accurate diagnosis. Dark-field X-ray images can differentiate between diseased and healthy lung tissue, potentially replacing computed tomography (CT) for repeated examinations.
A team of researchers has discovered how pore space geometry affects the transport of substances through complex porous media. By studying microchips with varying obstruction geometries, they found that branching and junctions play a crucial role in controlling the direction and speed of fluid flow.
Researchers at Technical University of Munich developed synthetic peptides that bind to proteins forming amyloids, preventing their aggregation. These peptides could be valuable candidates for treating both diseases, with potential for medical application.
A high-energy neutrino source has been detected in the spiral galaxy NGC 1068, providing new insights into the mysteries of active galaxies. The discovery was made using the IceCube Neutrino Observatory and statistical methods, allowing researchers to distinguish between the weak signal and strong background noise.
Researchers at Technical University of Munich discovered a material that can be n- or p-conducting by changing the temperature, enabling locally flexible diodes. The material, Ag18Cu3Te11Cl3, displays the desired effect in room temperature ranges.
Researchers developed a novel organoid model to study pancreatic cancer cells' growth and arrangement. The model provides insight into the three-dimensional structure of tumors, enabling tracking of individual growth stages, cell divisions, and gene expression patterns.
Researchers used machine learning algorithms to optimize climate models, increasing their accuracy and detail. By applying Generative Adversarial Networks (GANs) to climate simulations, the team was able to improve the models' ability to represent extreme precipitation events.
Researchers, led by TUM's Senthold Asseng, are exploring ways to close the genetic yield gap of 51% in wheat to meet increasing global demand. Utilizing advanced breeding techniques and interdisciplinary approaches combining genetics, soil, and climate science can lead to richer harvests.