Researchers are using bioprinting to grow cells in 3D scaffolds that can be used to regenerate tissue, with the potential to treat diseases such as cavity wounds. However, limitations include cell survival rates and guaranteeing consistent quality.
Researchers at the University of Manchester have identified 14 new genes linked to rheumatoid arthritis, shedding light on why the condition disproportionately affects women. The study's findings could lead to personalized treatment approaches and improved disease management.
A team from the University of Manchester has identified a molecular biomarker that can predict which breast cancer patients are most likely to respond to tamoxifen treatment. The discovery could lead to more effective treatment options for patients who have not responded to traditional therapies.
Researchers have identified a new molecular marker, β2-syntrophin, which can help differentiate between low-risk and high-risk types of prostate cancer. This breakthrough discovery could lead to more accurate diagnoses and personalized treatment plans, ultimately improving patient outcomes.
A study used next-generation sequencing to identify tuberculosis genes in a 19th-century skeleton, revealing a historic strain of the disease. The technology saved time and accurately identified DNA, paving the way for further research into the disease's evolution.
UK scientists have developed a new drug that primes the immune system to fight cancer, with promising early laboratory results showing it can lead to long-term survival in lymphoma patients. The treatment uses a chemical called R848, which signals to certain immune cells to attack cancer.
Scientists at the University of Manchester used CT scans to study a 16 million-year-old amber specimen revealing a springtail transported on an adult mayfly, a behavior never recorded before. The findings demonstrate the importance of the fossil record in understanding present-day animal behaviors.
Researchers created a multilayer cake using graphene and boron nitride to form a nanoscale electric transformer. The breakthrough paves the way for complex electronic devices with novel architectures.
The graphene-paved roadmap outlines the material's potential for transforming various industries, including electronics and medicine. With its unique properties, graphene is expected to play a crucial role in developing new technologies such as flexible devices, rollable e-paper, and high-speed wireless communications.
Researchers at the University of Manchester tested replicas of ancient Egyptian artificial toes, finding they may have been used as practical tools to help people walk. The tests showed that volunteers were able to achieve significant flexion with the prosthetic devices, indicating their potential use as early prosthetics.
A 15-year study found that brain parts can respond to evolutionary stimuli independently, contradicting previous concerted evolution theories. The research identified specific gene sets controlling the size of different brain parts, with little correlation between overall brain and body sizes.
Researchers have created 3D digital reconstructions of two 305-million-year-old juvenile insects using high-resolution CT scanning. The fossils provide valuable information about the biology and diet of these ancient insects, including one with sharp spines that may not exist today.
A team of researchers at the University of Manchester has found a novel solution to reducing inflammation by harnessing the power of hypertonic solutions. They discovered that bathing in or applying these solutions can shrink cells and deactivate the inflammatory response.
The Euro-26 study examined health, life expectancy, and lifestyles of 26 European cities, identifying major differences within individual urban areas. Key priority areas were found for each city, including depression and anxiety, cancer, and respiratory disease.
The 'magic carpet' technology uses plastic optical fibres to map a person's walking patterns and identify gradual changes or sudden incidents like falls. As many as 30%-40% of community-dwelling older people fall each year, making this technology vital for preventing accidents.
Researchers at the University of Manchester have developed a side-view imaging technique to visualize individual graphene layers in devices, finding that structures are remarkably stable even with multiple layers. This achievement has significant implications for the engineering of graphene-based computer chips.
Researchers have identified a potential new treatment for stroke by demonstrating the effectiveness of Anakinra (IL-1Ra) in reducing brain damage. The drug blocks inflammation and microglia cell activation, which contribute to brain injury following a stroke.
A recent UK study found that deaths by suicide among mental health patients treated at home have reached 150-200 a year, with rates nearly double those on mental health wards. The report recommends prioritizing home-treatment teams for suicide prevention and improving safety measures.
A new study from the University of Manchester confirms safety indicators for people taking anticoagulant drugs to regulate atrial fibrillation, a condition that increases stroke risk. The study found that patients with high INR levels were more likely to experience bleeding episodes.
A recent study published in Human Reproduction found that many common lifestyle choices, including smoking and alcohol consumption, have little effect on male fertility. Instead, factors such as ethnicity, occupation, and previous conception history may play a greater role in determining sperm quality.
Researchers at the University of Manchester have developed a new method to accurately measure dinosaur weight, reducing estimates for a Brachiosaur skeleton from 80 tonnes to 23 tonnes. The team's laser scanning technique provides a more accurate estimate of body mass, suggesting dinosaurs were not as massive as previously believed.
Researchers found that people with depression have impaired brain connectivity between regions associated with guilt and knowledge of socially acceptable behavior. This 'decoupling' occurs when individuals feel guilty or blame themselves, but not when they're angry or blaming others.
A University of Manchester study found Johnson's Baby Extra Sensitive Wipes equivalent to water in hydrating newborn skin, challenging current NICE guidelines. The trial involved 280 babies and showed no significant differences in hydration or secondary outcomes, except for a slight increase in napkin dermatitis.
A study found that female fat prejudice persists even after weight loss, with participants viewing thin women with a weight loss history as less attractive. The researchers also discovered that negative attitudes towards obese people increase when participants are falsely told that body weight is easily controllable.
Suicide rates among psychiatric in-patients have fallen by 29-31% between 1997 and 2008, according to a new study. Young patients and those with schizophrenia saw the largest declines. However, the risk of suicide for recently discharged patients may have increased over the same period.
A recent study found that 54% of microwaves in the UK are disposed of for cosmetic reasons or minor faults, and 85% can be safely repaired. Simple design changes could prevent these issues altogether, reducing waste and conserving resources.
Researchers at the University of Manchester have identified a protein called calpain that allows Listeria bacteria to spread infection within human cells. By blocking this protein, new anti-infective drugs may be developed to combat antibiotic resistance.
A new study by The University of Manchester found that obese women face discrimination in the job market, receiving lower starting salaries than their non-overweight colleagues. Body image and conservative personalities were also linked to obesity discrimination.
A new study by researchers at the University of Manchester found that orangutans build nests with a high degree of sophistication, using strong branches for structural parts and weaker ones for linings. The apes' choice of branch was dictated by its diameter and rigidity, indicating possible knowledge of mechanical properties.
Researchers used advanced technology to observe dying stars, revealing winds of gas and dust. The discovery solves the long-standing puzzle of stellar superwinds.
Researchers have discovered a novel link between lithium and body clocks in treating bipolar disorder. Lithium salts increase the strength of clock rhythms, which may lead to more effective treatments with fewer side effects.
A recent study published in Social Indicators Research found that small positive personality changes can lead to greater increases in happiness than earning more money, marrying, or gaining employment. Personality changes are strongly related to changes in well-being and contribute more to improvements in personal wellbeing.
A new study found Scotland's suicide rate surpassed that of England & Wales in 1968 and widened the gap by the early 1990s. The research suggests a significant increase in suicides among young Scottish men, particularly by hanging.
Researchers at the University of Manchester have created a transistor that may prove graphene's potential as the next silicon for computer chips. The new device uses a vertical direction and exploits graphene's unique features to overcome current leakage issues.
Research shows that better mental health services and safer hospital environments lead to a significant reduction in suicides among specific patient groups. The study's findings are based on data from 12,881 suicides in 91 mental health services between 1997 and 2006.
A lab study found that Gilenya, an MS treatment, reverses ventricular hypertrophy's symptoms and prevents fatal arrhythmias. Researchers discovered Pak1's role in heart disease and developed a potential new therapy.
Researchers at the University of Manchester discovered graphene oxide membranes that can selectively remove water while blocking other substances, potentially leading to new applications in filtration and separation
Scientists have detected Criegee biradicals, which react rapidly to form aerosols and clouds that can cool the planet. The discovery has significant implications for pollution and climate change, suggesting a natural mechanism for offsetting warming.
Researchers at the University of Manchester have successfully made graphene magnetic by introducing vacancies and nonmagnetic atoms. The study's findings hold promise for future applications in spintronics and electronics, despite the tiny magnetism observed.
Researchers found that changes in one part of the skull were linked to changes throughout, challenging the idea of independent evolutionary events. The study used genealogical data and simulated shifts in skull shape associated with human evolution milestones.
A University of Manchester research consortium found that UK carbon emissions targets could be met with significant expansion of both renewables and nuclear electricity by 2035. However, this would require a huge increase in nuclear power to make up for the loss of current nuclear stations.
The Manchester FLITES project aims to produce first-ever images of chemical species in aero-engine exhaust plumes using novel fibre lasers. The four-year study will focus on lowering carbon dioxide emissions, enhancing turbine-related research and development capacity.
A six-month telephone-delivered cognitive behavioural therapy (CBT) program improved symptoms of chronic widespread pain, with significant benefits reported three months after treatment ended. Exercise also showed substantial improvements in self-rated global health.
Researchers have produced the smallest arthropod fossil ever scanned using X-ray CT techniques, a 176-micron-long prehistoric mite trapped in Baltic amber. The study reveals almost 50 million years of evolution among these mites of phoretic behavior using another species.
A recent HIV study has identified SAMHD1, a protein that prevents the virus from replicating in certain cells. The research provides a blueprint for designing new drugs to treat HIV infection.
The study, 'Pedigree Chums: Science, Medicine and the Remaking of the Dog in the Twentieth Century', investigates the transformation of dogs through human selection and treatment, as well as their interactions with humans.
Researchers at the University of Manchester have developed a computer program that can rapidly identify ideal drug combinations to prevent inflammation and combat severe diseases. By analyzing billions of potential combinations, they hope to create tailored therapies for conditions such as stroke, cancer, and Alzheimer's.
Researchers discovered that antiviral agents can decrease the accumulation of AD proteins β-amyloid and P-tau in HSV1-infected cells. The study suggests that these agents might be effective in slowing Alzheimer's progression, targeting a cause rather than symptoms.
Researchers at the University of Manchester have created a graphene 'Big Mac' structure that isolates graphene from environmental influences, allowing for better electronic properties. This breakthrough enables the potential replacement of silicon chips in computers with graphene-based transistors.
Researchers have discovered how living organisms, including humans, protect themselves from carbon monoxide poisoning by altering the structure of haemproteins. This mechanism allows for safe levels of internal carbon monoxide production without impairing cellular functions.