Researchers at the University of Manchester have discovered a new mechanism that governs how body clocks react to changes in the environment. The enzyme casein kinase 1epsilon (CK1epsilon) controls how easily the body's clock can be adjusted or reset by environmental cues such as light and temperature.
A recent study by the University of Manchester found that only 2.1% of adults with significant hearing problems use a hearing aid. The study revealed that approximately one in 10 middle-aged adults have substantial hearing difficulties, particularly those from working-class or ethnic minority backgrounds.
Scientists at The University of Manchester discovered a rhythmic defence pathway in the lung controlled by our body clocks, essential for combating toxins and pollutants. The research found that timed administration of antioxidant compounds according to the lung clock time can increase their effectiveness and reduce side effects.
Researchers found that purified fish oils improved blood sugar levels in babies with congenital hyperinsulinism. The treatment, combined with standard medical care, has the potential to stabilize blood sugar levels and prevent long-term disabilities.
A new approach to prostate cancer screening is needed, focusing on high-risk men rather than the entire population. The risk-based approach uses a computer-generated calculator that assesses factors like PSA levels, family history, and ethnicity to identify those at greatest risk.
A new protein called Merm1 has been discovered to play a role in controlling cell growth and division in lung tissue. This finding could lead to the development of new drugs targeting lung cancer.
A new treatment approach in radioimmunotherapy has shown a high overall response rate of 94.4% and complete response in 69.4% of patients with follicular lymphoma. Researchers have found the treatment to be feasible and safe with minimal side effects.
New research suggests the UK can produce up to 44% of its energy needs from biomass sources like household waste and agricultural residues. The study highlights the potential for biomass resources to contribute significantly to the country's renewable energy targets.
A commonly-used HIV drug has been shown to kill-off the human papilloma virus (HPV) that leads to cervical cancer. The study found a high proportion of women diagnosed with HPV positive high-grade disease returned to normal following a short course of the new treatment.
Research at The University of Manchester found that moderate to heavy alcohol consumption in early pregnancy can reduce cell growth in the placenta. Drinking levels equivalent to half or one standard drink did not have a harmful effect, but reduced taurine transport from mother to baby was observed.
Researchers at the University of Manchester have discovered that graphene can be used to create ultrafast filters for liquid water, with an astonishingly accurate mesh that allows precise separation of atomic species. The filters also exhibit 'ion sponging' properties, sucking up small ions and concentrating them internally.
Scientists have discovered that herpes virus proteins use their flexible arms to pass on viral building blocks to hijacked cell proteins, providing insight into the virus's ability to hijack cells. The study's findings may lead to new treatments for Kaposi's sarcoma, a type of cancer caused by the herpes virus.
A new study has strengthened the link between alcohol consumption and breast cancer development. Researchers found that a particular enzyme, CYP2E1, plays a role in controlling the growth of breast cancer cells.
Scientists have combined Planck spacecraft and gravitational lensing observations to accurately measure the mass of ghostly sub-atomic particles called neutrinos for the first time. The team finds that massive neutrinos can explain the discrepancies between cosmological results and observations of large-scale structures in the Universe.
A simple protein test may help predict survival rates for patients with head and neck cancer by identifying HPV-positive tumours. This test could allow doctors to choose more appropriate treatments, leading to better outcomes for patients.
Scientists from the University of Manchester identified Leri's pleonosteosis as caused by extra genetic material on chromosome 8. The condition is also linked to scleroderma and offers opportunities for understanding and treating both diseases.
Researchers found that males' ability to monopolize a female drives the evolution of their sexual traits. Some species invest more in weapons, while others prioritize large testes for fertility. The study looked at over 300 species and revealed surprising variations in male investment.
Research by universities of Manchester and Keele found British Muslims with diabetes may avoid discussing fasting with GPs, leading to poor diabetes control and increased mortality risk. Many patients perceive GPs as lacking expertise in supporting them during Ramadan.
Research reveals that levels of depression and anxiety among people with severe rheumatoid arthritis are significantly higher than previously reported. The study suggests that routine screening for depression is crucial, as untreated depression can impact treatment outcomes. The researchers propose modifying the current disease activit...
A systematic review of literature found narrow dietary interventions to increase fruit and vegetable consumption in overweight children are unlikely to achieve long-term change. Broad public health strategies targeting nutritional education, parental support, and physical activity are necessary to tackle childhood obesity.
Researchers have found a potential new strategy to selectively kill pancreatic cancer cells while sparing healthy ones, using energy supply disruption. By blocking glycolysis, they observed a toxic calcium overload and cell death in cancer cells, but not in normal cells.
A study led by University of Manchester researcher Charlotte Brassey found that the leg bones of the tallest moa birds were similar to those of modern flightless birds that can run fast. The researchers used Finite Element Analysis (FEA) to estimate the weight and robustness of the moa, finding that different species had unique solutio...
A study by Manchester scientists found that women who undergo risk-reducing surgery have increased survival rates compared to those who don't. The research suggests that removing ovaries and fallopian tubes can reduce the risk of both ovarian and breast cancer by half.
A new study published in The Lancet has found that compression stockings are a cost-effective treatment for venous leg ulcers, reducing recurrence and nurse visits. While some patients may not prefer to wear the stockings, they offer improved value for money for the NHS compared to traditional bandages.
A study by The University of Manchester shows that improved safety measures and specialist community services can reduce suicide rates among patients at risk. Implementing key recommendations, such as crisis resolution and information sharing with criminal justice agencies, is crucial in preventing suicide deaths.
A new study found that hospital management of patients who self-harm in England has barely changed over the past 10 years, with 40% of those attending hospital not receiving a specialist psychosocial assessment. The treatment received also varied according to where they lived, suggesting a postcode lottery was still in operation.
A new study by the University of Manchester found that prosthetic hands are generally rated as more eerie and less human-like than robotic or human hands. However, prosthetic hands with a more human-like design were rated as less eerie.
A recent study from the University of Manchester found that tumor oxygen levels impact treatment response. By analyzing gene expression, researchers can predict which patients will benefit from hypoxia-reducing agents before radiotherapy.
A new study published in PLoS One found a strong association between racism and gun ownership among white Americans. The research also revealed that those who oppose gun control tend to have stronger racial biases, are more conservative, and live in southern states.
Researchers have discovered a steady change in the pulses of the Crab pulsar, indicating its strong magnetic field is moving towards the equator. The findings, made possible by a 42-ft telescope used to track ballistic missiles, provide insights into the star's interior and evolution.
A study by University of Manchester scientists found that less than 7% of cervical cancer patients in Kenya receive optimal treatment, leading to high mortality rates. The researchers are now seeking funding to implement simple changes in hospital procedures to improve cancer treatment in the country.
Researchers from the University of Manchester successfully recreated the walking and running movements of Argentinosaurus using computer simulations. The study provides new insights into the dinosaur's locomotion ability, dispelling previous suggestions that it was inflated in size.
Scientists have successfully assembled model cell membranes on graphene surfaces using Lipid Dip-Pen Nanolithography (L-DPN). This breakthrough enables the study of complex systems and processes in a controlled environment.
A new study finds that high carbon dioxide levels in the ancient atmosphere may have counteracted the effects of a weak young Sun, allowing life to thrive on Earth. The researchers used tiny air samples trapped in quartz rocks to reconstruct the atmosphere's composition, finding higher-than-expected CO2 levels.
A study by the University of Manchester team has identified a new pathway regulating immune responses in the gut that can protect against infection. This finding holds promise for developing a protective immune response during parasite infestations, potentially addressing a major public health issue.
Scientists developed a new imaging technique that maps an object's three-dimensional distribution of its nano-properties in real time. This 'X-ray vision' can be used to study materials, geology, environmental science and medical research.
A team of researchers from the University of Manchester used next generation sequencing techniques to analyze sub-fossilized insects in copal and found no evidence of ancient DNA. The study suggests that DNA survival in resin inclusions is unlikely, raising doubts about claims of DNA extraction from fossil insects in amber.
Researchers at The University of Manchester and medical institutes in Italy have identified a gene variant associated with vasospasm, a rare cause of heart attacks. This discovery could lead to the development of new drugs to treat this condition.
Researchers from The University of Manchester have identified two new proteins that could predict women at risk of developing pre-eclampsia in their first pregnancy. These proteins, PSG5 and PSG9, were found to be as good a predictor of disease risk as the current best marker, placental growth factor.
A growing population of older male prisoners requires better health and social care in prisons. The study found that many prisons lack policies for caring for older prisoners and fail to integrate health and social services.
Research by scientists at The University of Manchester and Lancaster shows maintaining healthy soil biodiversity can play a key role in optimising land management programmes. The study found consistent links between soil organisms and ecosystem functioning on a large scale, across European countries.
A new species of tiny gnat, Proceroplatus preziosii, has been discovered on the Caribbean island of Hispaniola and named after Professor Richard Preziosi. The discovery was made by Dr. Dave Penney, who received ongoing support from Preziosi for his research into amber rocks.
Historian Dr Ian Burney's research shows that French Edmond Locard and Austrian Hans Gross were influenced by British writers Arthur Conan Doyle and R Austen Freeman, who advocated for a professionalised CSI. This led to the systematisation of methods in crime scene investigation.
Researchers from the University of Manchester have developed a new stem cell gene therapy to treat Sanfilippo, a fatal genetic brain disease. The treatment has shown promising results in mice, producing near-normal levels of SGSH enzyme and correcting progressive dementia and hyperactivity.
A new study has found a link between high levels of arsenic in rice and elevated genetic damage in humans. Researchers discovered that people consuming rice with more than 0.2 mg/kg arsenic showed higher frequencies of micronuclei, a sign of chromosomal damage.
Researchers have found a naturally occurring molecule, Urocortin, which protects cells in the joints from being destroyed in osteoarthritis. The discovery could lead to the development of new medicines to prevent joint degradation.
A team of international researchers discovered four fast radio bursts from cosmological distances, suggesting they originate from extreme events involving relativistic objects. The findings provide a way to study space between galaxies and understand the properties of missing matter in the Universe.
A collaborative EU-funded project aims to discover and develop novel antifungal drugs to combat drug-resistant fungal infections, which kill two million people annually. The NOFUN project brings together partners to accelerate development of broad-spectrum antifungal agents with new modes of action.
The UK chemical industry must radically transform its production processes to achieve absolute emission reductions by 2050, according to a new report. The sector's energy intensity and reliance on high-emission feedstocks pose significant challenges to meeting the Government's 80% greenhouse gas reduction target.
A new study by the University of Manchester found that patient suicide and homicide risk is often poorly assessed, with unsatisfactory assessments in about a third of cases. The researchers emphasize the need for individually tailored risk management, moving away from a 'tick-box' approach.