A study by the University of Manchester and Liverpool John Moores University found that courts imposed excessive and arbitrary punishments during the 2011 English riots. The research suggests that both courts and law enforcement agencies were influenced by a desire to restore order, leading to a 'collective hysteria' approach.
Scientists at the University of Manchester have identified a novel process for lowering pollutant toxicity using vitamin B12, offering new hope for combating hazardous substances. The research builds on 15 years of investigation into natural organisms that can detoxify pollutants.
Researchers have identified a novel gene, MGST3, that regulates hippocampus size in both mice and humans, linked to neurodegenerative diseases like Alzheimer's. The discovery provides another biomarker for identifying those at greatest risk of developing the condition.
An international team of astronomers observed a nova explosion using radio telescopes combining data from hundreds to thousands of kilometers apart. They discovered how the gamma-ray emissions are produced, a phenomenon that mystified scientists when first observed in 2012.
Researchers developed a new test that determines which drugs are unlikely to work by analyzing their structural similarity to naturally occurring substances. The 'rule of 0.5' shows a strong correlation between marketed drugs and metabolites, indicating that molecules with low similarity are unlikely to succeed.
Researchers at the University of Manchester argue that environmental scientists should provide more practical solutions to climate change, but recognize the need for a broader skill-set. They suggest integrating social science and humanities to enrich public debates about responding to environmental change.
A new study finds that shale gas has comparable greenhouse gas emissions to conventional natural gas, but is better than renewables in some areas. However, it's worse than coal in others. The researchers recommend strict regulation to mitigate the environmental impacts of shale gas.
Scientists at The University of Manchester have created a new star-shaped molecule consisting of two molecular triangles entwined about each other three times into a hexagram. This complex structure is the most advanced of its kind ever produced and has potential applications in creating light, flexible, and strong materials.
Scientists have found a 'cell-like' structure in a Martian meteorite that once held water, providing further evidence for the possibility of life on Mars. The discovery, published in Astrobiology, suggests that beneath the surface, Mars provides conditions for life to have formed and evolved.
Fossils of a shark egg case, horseshoe crabs and seed pods have been discovered in Doncaster, providing a window into a tropical water-logged forest teeming with life. The finds are believed to be rare and significant, offering insights into the geological history of Yorkshire.
Researchers at MIT and Manchester University have created a new material that allows electrons to move at controllable angles, resulting in more efficient computing. This breakthrough enables the development of transistors with lower energy consumption.
Researchers have developed a graphene-based paint with exceptional barrier properties, making it suitable for various industrial applications. The coating can provide complete impermeability to gases, liquids, and strong chemicals, rendering it ideal for protecting equipment in harsh environments.
Researchers have discovered bacteria that can survive in highly alkaline conditions expected in radioactive waste disposal sites and use isosaccharinic acid as a food source. These microbes may prevent the release of toxic radionuclides into the environment, offering a potential solution for safe nuclear waste disposal.
Scientists have successfully demonstrated how combining hexagonal boron nitride and graphene can create perfect crystals capable of being used in ultra-high frequency devices. The research paves the way for innovative applications in high-frequency electronics.
A new blood test developed by researchers at the University of Manchester and The Christie NHS Foundation Trust may soon be used to tailor treatment for ovarian cancer patients. The test predicts patient response to targeted therapies such as bevacizumab, allowing for personalized treatment plans while sparing those unlikely to benefit.
A new study published in PLOS ONE suggests that the current way of diagnosing type-2 diabetes using blood glucose levels needs to be revised. The researchers found changes in blood fat metabolites before glucose levels increased, indicating a potential alternative approach for diagnosis and treatment.
A new study found that written care plans and care planning in UK GPs are used rarely, leading to limited benefits for patients with long-term conditions. Despite the potential for improved management, the study showed no significant relationship between care plans, care planning, and patient outcomes.
Manchester scientists have developed a method to personalize and increase radiotherapy doses for lung cancer patients, potentially improving local control and survival rates. The technique uses intensity modulated radiotherapy (IMRT) to minimize harm to healthy tissue.
A new study found that 27% of rheumatoid arthritis patients in the UK failed to take their expensive anti-TNF therapy as prescribed. Non-adherence to medication reduced its effectiveness and worsened disease outcomes, highlighting a significant concern for healthcare resources.
Researchers have developed a new method to identify and measure vital molecules that control cell behavior, paving the way for better diagnosis, prediction, and monitoring of cancer. The study identified over 200 protein kinases and created a technique to quantify their levels in biological samples.
Acute pancreatitis is a severe condition where the pancreas digests itself, leading to abdominal pain, vomiting, and systemic inflammation. Recent research suggests that insulin may prevent toxic effects of alcohol and fatty acid metabolites on pancreatic acinar cells.
A pay-for-performance scheme introduced in the North West region of England reduced patient deaths in the first 18 months but had no further impact. Meanwhile, quality of care continued to improve over two years.
A recent study has shown that a lung cancer diagnosis tool can be used safely in elderly patients, allowing doctors to make more accurate diagnoses and choose appropriate treatments. The tool, known as EBUS-TBNA, is effective for assessing whether a patient's tumour has spread to the lymph nodes.
Scientists from The University of Manchester discovered that drugs used to treat asthma and pneumonia become ineffective due to the body's natural circadian rhythm. The study found that cells lining the lung airways have their own internal clock, which regulates inflammation in the lungs.
A new study published in the Emergency Medicine Journal suggests that combining clinical judgement with electrocardiogram and blood tests can effectively reduce unnecessary hospital admissions for chest pain. The findings could make a huge difference to a large number of patients, particularly in regions with high incidence rates of he...
Researchers have found that mental health patients are at their highest risk of dying by suicide in the first two weeks after leaving hospital. The study, which analyzed data from 2002 to 2012, shows that around 3,225 patients died by suicide within three months of discharge, with 526 deaths occurring within the first week.
Research found Aspergillus fungus resistant to life-saving drugs in UK rural areas treated with fungicides. The study highlights a worrying link between fungicide use and the emergence of multi-resistant fungal strains posing a significant threat to transplant patients and those with weakened immune systems.
Researchers used electronic health records to monitor the impact of treatments on patients with high-risk cardiovascular disease and chronic obstructive pulmonary disease. The study found that using EHRs simplified clinical trials, saving time and money for taxpayers, while maintaining minimal patient involvement.
Researchers at the University of Manchester discovered a new drug, AZD3965, effective in treating small cell lung cancer. The treatment approach exploits the change in energy production in tumours, targeting monocarboxylate transporters involved in lactate movement.
Research finds gut hormone cells, previously thought to contain one hormone, actually secrete six hormones including ghrelin. The discovery sheds light on how weight-loss surgery can cure diabetes, with understanding these hormonal changes crucial for a potential cure.
Researchers used exceptionally preserved fossils and computer graphics to recreate the most likely walking gait of a 410-million-year-old arachnid. The study, published in the Journal of Paleontology, provides new insights into the evolution of early land animals.
Research found that people with bipolar disorder have stronger brain activity in the 'pleasure centre', guiding them towards riskier decisions. In contrast, a healthy control group's prefrontal cortex guides safer choices. This study aims to design and monitor therapies for bipolar disorder using neuroscience.
Researchers have discovered how embryonic stem cell fate is controlled, enabling future research into artificial cell manipulation. This breakthrough aims to repair or replace damaged human cells and tissues, restoring normal function.
A new liquid biopsy test uses circulating tumour cells in blood samples to monitor and predict lung cancer response to treatment. The test has the potential to provide personalised medicine for the disease, particularly for small cell lung cancer with poor survival rates.
Researchers at the University of Manchester have discovered how melanoma drugs can lead to cancer progression when treatment is stopped. Using a combination of BRAF and MEK inhibitors shows promise in combating drug resistance in advanced metastatic melanoma.
Researchers at the University of Manchester have discovered that combining graphene with boron nitride creates an additional band gap, allowing for more control over its electrical conductivity. This phenomenon, known as the Hofstadter butterfly, results in strongly contorted replicas of the original graphene spectrum.
Researchers developed a sophisticated computer modelling simulation to explore how fruit fly cells respond to temperature changes during development. The model shows how cells communicate with each other, providing insights into cell signalling networks.
Scientists have discovered a new drug that significantly improves the effectiveness of radiotherapy in stopping tumor growth and increasing long-term survival. The combination treatment reduces secondary lung tumors and demonstrates potential for improved cancer treatment.
A new study reveals that athletes who have a lifelong history of endurance events may experience abnormal heart rhythms due to molecular changes in their heart's pacemaker. Elderly athletes are more likely to need artificial pacemakers fitted compared to normal adults.
A majority of UK adults perceive alcohol adverts as breaching the Advertising Standards Authority's Code, with over 75% rating at least one rule breached. The study highlights the need for further consideration of co-regulation and reporting of breaches.
Researchers used synchrotron-imaging to examine 150-million-year-old predatory dinosaur bones, discovering that many healed injuries were not fatal to humans. The study sheds light on the chemical signatures of bone healing and remodelling strategies in extinct vertebrates.
Scientists successfully create 'heterostructures' with novel functionalities, such as tunnelling transistors and solar cells. By controlling the relative orientation between graphene and boron nitride, researchers can reconstruct the crystal structure of graphene and open a band-gap.
Immunology is the study of the human immune system, which seeks out and destroys dangerous bacteria, viruses, and fungi. It also explores how its activity connects with other body systems, influencing metabolism, hormone levels, and overall well-being.
Scientists have identified a potential new strategy to treat ovarian cancer by targeting multiple growth factors. By blocking several avenues that tumour cells use to escape eradication, researchers hope to develop new anticancer drugs that target ovarian tumour growth.
Researchers at the University of Manchester discovered a key role for protein Bid in mitosis-related cell death, which may help overcome chemotherapy resistance in colon cancer. By targeting Bid, resistant cells can be made more susceptible to treatment.
A University of Manchester study reveals that infection after a stroke significantly worsens outcomes, with the immune system's response to the infection causing more damage. Researchers identified specific blood cells and molecules involved in this process, paving the way for potential anti-inflammatory therapies.
Researchers have discovered a 305-million-year-old harvestman fossil with two sets of eyes, challenging previous assumptions about the evolutionary history of arachnids. The fossil's exceptional preservation allows scientists to study its anatomy in unprecedented detail.
Researchers found that galanin plays a crucial role in stress mechanisms and influences depression risk, particularly in those with early life neglect or trauma. A new class of antidepressant drugs targeting galanin functionality may provide effective treatment options for patients.
Researchers have identified genetic variants associated with two forms of rheumatoid arthritis, sero-positive and sero-negative. This breakthrough could lead to better diagnosis and targeted treatment for patients.
Researchers exposed biochemical structure of fossil leaves to visualize the chemistry of exceptionally preserved fossil leaves. The study reveals that the distribution of copper, zinc, and nickel in fossil leaves is almost identical to modern leaves.