Only 20% of children with persistent asthma have optimal control, according to a survey-based study published in Ambulatory Pediatrics. The study found that 43% of children receiving medications still experienced poor symptom control, highlighting the need for improved education and trigger avoidance strategies.
A study by the University of Rochester Medical Center has found a link between phthalate exposure and increased belly fat and insulin resistance in men. The research suggests that low-dose exposures to phthalates may contribute to rising obesity rates and related disorders such as Type 2 diabetes.
A study published in Archives of Pediatric and Adolescent Medicine found that children under ongoing family stress have more fevers with illness than other children. Interestingly, the immune system's natural killer cell function in these children also increases, unlike adults who experience decreased function.
A study published in Pediatrics confirms the effectiveness of MMR and chicken pox vaccines in extremely preterm infants, contradicting previous concerns about their immune systems. The study found that both term and preterm infants reached a level of immunity considered protective against these diseases.
A recent study published in Pediatrics has found that repeated courses of steroids in preterm labor do not harm the babies' brains, contrary to previous concerns. The treatment may still hold promise for helping fragile babies breathe on their own and reducing the risk of respiratory complications.
A case report suggests that light streaming through whirling helicopter rotor blades during medical air transport can cause symptoms ranging from nausea to full-blown seizures. Researchers recommend shielding patients' eyes to prevent this under-recognized but highly preventable complication.
Researchers identified a new route to cancer treatment by exploiting mutations that control cell movement. Understanding the collaboration between Ras and p53 genes may lead to novel therapeutic targets like Rho proteins.
A study published in PLoS Biology finds that low levels of toxic substances cause critical stem cells to prematurely shut down. The research identifies a common molecular trigger for the effects of toxicant exposure, offering new insights into damage caused by toxicant exposure and potential methods to evaluate chemical safety.
Researchers have discovered a new way to fight colorectal cancer by targeting the 'skeletons' of cancer cells, which enable them to reproduce and spread. High-dose PPARgamma inhibitors destroy cancer cell microtubules, reducing their ability to grow and metastasize.
A study published in Inhalation Toxicology found that rats exposed to highway pollution showed a significant drop in heart rate and disruption of the autonomic nervous system. This discovery highlights the potential risks of air pollution on cardiovascular health, particularly for individuals with pre-existing heart disease.
The number of individuals with Parkinson's disease is projected to nearly double globally by 2030, with the majority of growth occurring in developing countries in Asia. This growth will be driven by increasing life expectancy and growing economies, which will lead to increased healthcare spending and a greater burden on societies.
A new study found that rapid flu tests can significantly reduce the use of antibiotics in hospitals, which is crucial in combating antibiotic resistance. The study showed that patients whose flu was confirmed early on were treated with antibiotics less often than those whose flu wasn't identified immediately.
Scientists have made a surprising connection between Alzheimer's disease and the body's arterial system. Reduced blood flow in the brain precedes cognitive decline in patients with Alzheimer's disease.
Obese and less educated women with breast cancer are more likely to receive reduced chemotherapy doses, threatening their survival. Research shows that doctors often reduce doses for these patients without solid medical basis, highlighting treatment disparities in cancer care.
A study found that herpes simplex virus, which causes cold sores, may be more active in the brains of people with the ApoE-4 gene variant, a known risk factor for Alzheimer's disease. The research suggests that ApoE-4 may alter the balance between the HSV life cycle forms, potentially increasing the risk of Alzheimer's.
Rotating treatment through different types of medications can help avoid worsening symptoms in patients with restless leg syndrome, say experts. The team recommends switching treatments when symptoms appear or before augmentation occurs.
A recent study published in Obstetrics & Gynecology reveals that nearly half of young pregnant women are unaware of the safety and effectiveness of modern intrauterine devices (IUD). The study suggests that counseling about IUDs could help these women make informed decisions about contraception.
Researchers found that manipulating proteins in the immune system could lead to new treatments for asthma, which shares similarities with parasitic infections. The study's findings suggest that targeting specific cytokines, such as IL-4 and IL-13, may help prevent lung damage in asthmatic patients.
A study of 160,000 women screened in their 40s compared to those in their 50s found little change in estimated overall survival. The authors conclude that the benefits of early detection may outweigh the risks of radiation-induced breast cancer, but the uncertainty remains too great to make a definitive recommendation.
A University of Rochester study published in Obstetrics and Gynecology journal found that low doses of mifepristone shrink uterine fibroid tumors and greatly improve the quality of life in women who suffer from pain and heavy bleeding. The treatment resulted in a 135% improvement in quality of life for women taking mifepristone compare...
A groundbreaking study by neurologist Steven Goldman and his team used stem cells to treat Parkinson's disease in rats, achieving a remarkable improvement in symptoms. However, brain tumors appeared due to the stem cells' uncontrolled growth, prompting an urgent need to find solutions.
A study by University of Rochester Medical Center researchers found that black patients are more likely to prefer life-sustaining care when faced with an incurable illness or serious disabilities. In contrast, white patients were less inclined to accept such care. The differences in attitudes suggest a need for healthcare policies sens...
Researchers at the University of Rochester Medical Center found that common chemotherapy drugs can be toxic to healthy brain cells, causing long-term damage and cognitive impairment. The study suggests that these drugs can disrupt neurogenesis and destroy oligodendrocytes, leading to significant neurological consequences.
Research suggests that common painkillers like NSAIDs can reduce vaccine effectiveness by reducing antibody production. The study's findings have implications for people who take these medications regularly, particularly those with compromised immune systems.
The Cone Beam Breast Computed Tomography (CBBCT) scanner produces three-dimensional pictures of breast anatomy to distinguish benign lesions from tiny cancers. The pilot study showed promising results, with one case demonstrating a cancer that was hard to detect on a mammogram.
A device implanted in US patients with severe hypertension shows significant reduction in blood pressure, averaging 22mmHg systolic and 18mmHg diastolic. The Rheos System activates the body's baroreflex system to lower blood pressure through electrical stimulation.
Researchers at the University of Rochester Medical Center have developed a new artificial cornea that improves vision in infants and children with cloudy or damaged corneas. The device shows promising results, restoring vision and eliminating the need for repeated surgeries and infections.
A new study shows that shaped-beam radiosurgery can treat the smallest lung tumors, allowing patients to live disease-free for years. Researchers found that 91% of treated tumors never progressed and 25% of patients were cancer-free after three years.
A study published in Pediatrics reveals a significant increase in children's abdominal obesity, with boys experiencing a 65% rise and girls a 70% increase between 1988 and 2004. This growing trend poses serious health risks, including cardiovascular disease and metabolic syndrome.
Researchers at the University of Rochester Medical Center have developed a potential new treatment for stroke using Activated Protein C, which has shown promise in reducing brain damage by 70 percent. The treatment aims to temper the side effects of current medication TPA and expand its 'window' beyond three hours.
Research suggests that common antacids like lansoprazole can interfere with bacteria that cause plaque buildup and gingivitis. By disabling these bacteria, the compounds may prevent inflammation and damage to gums. If confirmed in future studies, these compounds could be widely available in oral care products.
A new stretch targeting the plantar fascia has shown significant results in treating plantar fasciitis, with 75% of patients experiencing no pain and full activity within 3-6 months. The stretch, developed by Benedict DiGiovanni and Deborah Nawoczenski, requires repeated stretching exercises to alleviate chronic symptoms.
Researchers have determined the APOBEC-3G protein structure, providing key insights into its role in the immune system and potential as a drug target. The study suggests that editing errors introduced by A3G can help defend against HIV, and future drugs may be designed to replicate this natural protection.
A team of researchers has identified a new genetic mutation responsible for osteogenesis imperfecta (OI), a condition that makes bones more likely to break. The study found that mutations in the CRTAP gene reduce the ability of a protein involved in collagen formation, leading to weaker bone and increased risk of fracture.
Researchers at the University of Rochester Medical Center have received a $7.8 million grant to develop new treatments for bone fractures and arthritis. The team will explore ways to predict who is likely to suffer from osteoarthritis after injury and create targeted drug therapies to prevent it.
A nationwide team of researchers has discovered several new biochemical pathways that play a central role in post-trauma immune system and organ failure. The study identified the genetic and protein changes in specific immune cells that determine whether trauma is fatal, providing potential insights into many diseases involving human i...
A booster shot given before a primary immunization may protect people against bird flu. Studies in Rochester suggest that adults who have never encountered the virus would benefit from an additional dose.
Experimental drugs show promise against neuroAIDS, a growing concern despite best antivirals. New grant aims to protect brain from HIV-related nerve damage using compounds that counter toxins and reduce inflammation.
A University of Rochester study found that African Americans and Latinos are more likely to over-report their last preventive screening test, potentially harming their health. The research highlights the need for accurate tracking of ethnic disparities in healthcare.
Researchers will analyze FDA database of electrocardiograms to identify early predictors of cardiac risk and develop new biomarkers for drug toxicity. The goal is to improve the safety of new drugs while reducing development costs.
The University of Rochester Medical Center is establishing a leading program in Cancer Stem Cell Research to discover cures for cancer. By studying the 'master cells' of this deadly disease, scientists aim to find underlying causes and develop therapies to target cancer stem cells.
A new formula developed by doctors at the University of Rochester Medical Center reduces farsightedness among LASIK patients, making it more likely to get vision right the first time. The formula takes into account various imperfections in the eye that were not previously known to exist.
Physiologic Communications is developing an implantable biosensor that can detect physiologic and chemical changes with faster accuracy than current methods. This 'living chip' has the potential to revolutionize disease monitoring by providing real-time data to physicians and enabling timely interventions.
A new study by the University of Rochester Medical Center found that genetic defects, particularly those related to Long QT Syndrome (LQTS), are significant risk factors for sudden cardiac death in teenagers. The study also identified changes in puberty among teens with LQTS as a predictor of life-threatening events.
A study of 124 women found that hormone-replacement therapy with progestin resulted in a 10-30% increase in hearing loss compared to estrogen-only or non-HRT groups. Women on progestin showed signs of damage in both the inner ear and brain used for hearing.
A recent study by the University of Rochester Medical Center found that lead exposure is associated with an increased risk of brain cancer in adults. The research, which analyzed data from over 318,000 people, revealed a 50% higher death rate among those exposed to lead compared to unexposed individuals.
Researchers at the University of Rochester Medical Center are working to reverse paralysis and lessen spinal cord injury effects through new projects funded by speeding fines. The grants support studies into nerve regeneration, astrocyte role, and remyelination.
Researchers are investigating antioxidants for preventing or treating rickettsia bacteria, a deadly tick-borne illness. The study, funded by the National Institute of Allergy and Infectious Disease, aims to identify novel therapeutic targets for rickettsial diseases.
A unique medical research study has begun evaluating 1,001 individuals at risk of developing Huntington's disease who do not know whether they carry the genetic defect. The PHAROS study aims to identify early signs of the disease and inform clinicians in designing better studies for new drugs.
A new screening program using digital cameras and the Internet effectively identifies early childhood dental caries (ECC) in 40% of toddlers. The program, developed by University of Rochester Medical Center researchers, uses photos taken by child care center health assistants to detect ECC before it becomes a painful problem.