Articles tagged with Flu Vaccines
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The study found no new or unexpected adverse events, including rare events, reported to VAERS during the first two post-licensure seasons of intranasal flu vaccine use. The researchers identified some potential risks, such as anaphylaxis and asthma exacerbation in individuals with prior asthma history.
Researchers developed a vaccine platform offering protection against pneumocystis, influenza, and other pathogens in immunocompromised individuals. The vaccine uses a specific antigen and CD40L molecule to induce an immune response.
A Johns Hopkins expert recommends making flu vaccination mandatory for healthcare workers to prevent outbreaks. Despite high vaccination rates, nearly 40,000 Americans die from influenza each year, and voluntary programs have shown limited success.
Study identifies chronic conditions, including NNMD, as increasing risk of respiratory failure in children hospitalized with influenza. Children with these conditions are 6-4 times more likely to develop respiratory failure compared to those without.
A team of researchers from the University of Wisconsin-Madison and the University of Tokyo report a new way to generate genetically altered influenza virus. This technique improves upon a previous reverse genetics method by significantly reducing the number of plasmid vectors required, increasing the efficiency of virus production.
Pall Corporation's total process management approach can improve vaccine production economics by reducing time, safety risks, and expenses. The use of scalable and disposable technologies enables efficient processing of larger volumes, addressing the need for increased manufacturing capacity in response to pandemic threats.
A new vaccine study is testing a targeted vaccine against the H5N1 strain of avian influenza, aiming to protect vulnerable populations. Participants will receive three doses of either the vaccine or placebo over six months, with blood samples collected to test for protection.
A DNA vaccine could be a powerful tool to combat the 'bird flu' pandemic, potentially produced in as little as two or three weeks. The technique is largely untested in humans, but it might help slow the spread of the disease if enough conventional vaccines aren't available.
Health officials should consider alternative options due to high flu virus resistance to Tamiflu, a key drug in pandemic preparedness. The discovery raises concerns about the effectiveness of stockpiled doses and may require reevaluation of global strategies.
The study found that drug resistance increased from 0.4% in 1994-1995 to 12.3% in 2003-2004, with 61% of resistant viruses coming from people in Asia. This alarming trend has significant implications for agencies and governments planning to stockpile anti-flu agents.
A study found that less than 8% of nurses and healthcare assistants had annual flu injections, citing lack of knowledge as a major reason. The research also showed that over 51% of respondents took sick leave due to flu-like illnesses during the survey period.
A study found that routine immunisation of infants with the Haemophilus influenzae type b (Hib) vaccine significantly reduced meningitis incidence rates in The Gambia. The researchers hope their findings will encourage other developing countries to adopt Hib vaccination programmes, helping achieve the United Nations' goal of decreasing...
The US vaccine system is fragile and needs significant improvements, the authors report. Despite record low levels of vaccine-preventable diseases and high immunization rates among children, supply chain issues, cost concerns, and safety threats threaten to derail progress.
The vaccine industry has declined from 26 companies in 1967 to just five in 2004 due to low market demand and high production costs. Dr. Paul Offit urges legislators to protect vaccines as a vital instrument of public health and recommends financial incentives for manufacturers and healthcare professionals
A combination vaccine for pneumococcus and meningococcal conjugate showed reduced group C meningococcal immunogenicity compared to separate vaccines. The study, conducted from 2000-2002, found the combination vaccine was safe but not suitable as a replacement for individual vaccines.
A study by Ohio State University researchers found that short bouts of social stress improved the ability of mice to recover from the flu. The stress boosted the production of specialized immune cells called T cells, which fight viruses. This finding may lead to more effective flu vaccines for older adults.
Researchers found that short-term stress in mice enhanced their immune reaction to influenza, leading to faster and more successful recovery. This discovery has broad implications for vaccine development, suggesting new strategies could be developed to boost immunity against influenza and potentially other diseases.
The National Institute of Allergy and Infectious Diseases (NIAID) is conducting a Phase I trial to test the safety and immune response of an inactivated H5N1 avian influenza vaccine. The trial aims to prepare for a potential pandemic, following reports of human cases and suspected transmission.
A new influenza vaccine developed using insect cells can produce a strong immune response in humans and may be scaled up for commercial manufacture. This rapid method uses a purified concentration of hemagglutinin to elicit an immune response against specific flu strains.
Researchers identified a dozen potential facilities worldwide that could manufacture flu vaccines in emergency situations. Cell-based vaccines have the potential to reduce production time and improve flexibility compared to traditional egg culture methods.
A study found that many US children are undervaccinated or have delayed vaccinations in their first 2 years of life. The researchers discovered that on average, children were undervaccinated for 172 days during this period.
Vaccination of healthy children in the US and Canada shows limited efficacy in reducing disease spread, hospitalizations, and complications. The study's findings suggest that immunization of very young children does not support a reduction in mortality and community transmission.
A large-scale study shows that flu vaccination is highly effective in reducing severe end points such as deaths and hospitalizations among high-risk persons of working age. The vaccine benefits people of any age with high-risk medical conditions, not just the elderly.
A recent study found no correlation between increasing flu vaccination coverage in the elderly and declining death rates. The authors suggest that this disconnect may be due to disparities in who is likely to receive vaccination, particularly among those with fragile health. This finding has implications for influenza vaccination policy.
Vaccinating 70% of school children, ages 6 to 18, can reduce community-wide transmission to very low levels. This strategy is more effective than vaccinating only high-risk groups.
At the University of Rochester Medical Center, a team of nurses led by Diane O'Brien and John Treanor developed a system to inoculate over 200 volunteers with an experimental flu vaccine. The study aimed to assess the safety and effectiveness of the vaccine in preventing another flu vaccine shortage.
A vaccine against cervical cancer has been developed by Dutch researcher Laura Bungener. The vaccine induces an immune response to proteins from human papillomavirus (HPV), rendering it harmless and preventing the growth of tumors. Laboratory animals with existing tumors could also be treated with this vaccination.
A NIAID-sponsored clinical trial is enrolling healthy adults to assess the immune response and safety of the Fluarix vaccine, which has been distributed in over 70 countries. The trial will provide valuable information on the vaccine's efficacy before it can be licensed for use in the US.
Researchers found a significant decline in Guillain-Barré syndrome (GBS) reports following influenza vaccination, with annual rates decreasing by 4-fold between 1993-1994 and 2002-2003. A GBS diagnosis was confirmed in 82% of reports, and preceding illness within 4 weeks of vaccination was identified in 24% of cases.
A randomized trial found that computerized standing orders for influenza and pneumococcal vaccines significantly increased vaccine administration rates compared to physician reminders. Patients with standing orders received vaccinations 12-24% more often, highlighting the effectiveness of this approach in improving preventive care.
A new study found that computer-assisted standing orders for nurses resulted in significantly better adult immunization rates compared to traditional physician reminders. The study showed that 42% of patients in the standing order group received influenza vaccine, while only 30% in the physician reminder group did so.
Researchers at Saint Louis University discovered a new flu vaccine solution that uses lower doses in younger adults, which could stretch the nation's vaccine supply by up to 2.5 times. This innovative approach involves administering the vaccine intradermally, between the layers of skin, rather than through a traditional muscle injection.
A study of 26,071 elderly individuals found that annual influenza revaccination was associated with a reduced mortality risk of 24% compared to first-time vaccination. Revaccination after an interruption resulted in a similar mortality risk reduction as seen after the initial vaccination.
Researchers are testing a new flu vaccine grown in insect cell lines, which could reduce production time by one to two months. The study aims to evaluate the effectiveness of the experimental vaccine in healthy adults aged 18-49, with potential benefits including reduced costs and increased dose strength.
The influenza vaccine faces production challenges, with Chiron's manufacturing troubles affecting UK and US supplies. To mitigate this, manufacturers are diversifying their output to ensure vaccination for high-risk groups is maintained.
Researchers are testing the effectiveness of both flu shots and nasal sprays to determine which one provides better protection against influenza. The study aims to gather valuable information for influenza pandemic planning and control annual outbreaks.
The study found that spring-fall flu shots were as effective as traditional fall schedules in protecting toddlers from flu complications. Additionally, the spring-fall schedule allowed children to receive their immunizations earlier and completed their vaccination process faster than those in the standard fall group.
Pediatricians and family physicians surveyed by researchers from the University of Rochester Medical Center support expanding flu vaccination to healthy infants and toddlers. The study found that 58% of doctors would favor this expansion, despite citing high costs and parental concerns about vaccine safety as major barriers.
A survey of pediatricians and family physicians found that 80% of pediatricians and 69% of family physicians believed a universal influenza vaccination program for infants would be feasible. The majority also agreed that the vaccine would greatly decrease sickness during the influenza season.
The NIAID Pandemic Influenza Preparedness Program supports the development and production of a candidate vaccine against H9N2 avian influenza. The vaccine will be produced by Chiron Corporation in Italy, with different dosages containing an adjuvant to boost its protective effect.
A study found that adults with regular doctors were more likely to receive influenza vaccinations and mammography, as well as advice on smoking cessation. This suggests that trust in a single provider contributes to better adherence to health recommendations.
A study led by Baylor College of Medicine and the University of Rochester Medical Center is testing a vaccine against H9 bird flu, which infected several people in Hong Kong in 1999. The goal is to prepare for potential transmission of the virus from person to person.
Using targeted antiviral prophylaxis (TAP) on close contacts of suspected flu cases can effectively contain an epidemic, with only 2% of the population becoming ill and a death rate of 0.04 per 1,000 people. TAP is nearly as effective as vaccinating 80% of the entire population, especially when used for eight weeks.
A new protein called VLA-1 enables the immune system to develop peripheral immunity by anchoring virus-killing cells to tissues in the lungs. This allows for an instant strike against flu viruses, potentially delivering a better defense against deadly strains like avian flu.
The study found that inactivated influenza virus vaccines are effective in protecting children against the flu, reducing hospitalization rates comparable to those of elderly people. Vaccinating children can also protect adults from getting infected and save money on treatment costs.
Researchers are testing a new flu vaccine that delivers the vaccine in the nose to observe differences in immune system reactions. The study aims to improve immunity in the respiratory tract for all pathogens, with implications for biodefense.
Recent studies suggest that pediatric influenza is a significant medical problem, causing excess hospitalizations and antibiotic prescriptions. Experts call for increased efforts to identify and vaccinate high-risk children, as well as educating parents and physicians about the importance of flu vaccination.
This year's flu season is severe due to a mutated virus that has changed slightly since last year's vaccine was designed. Young children are at higher risk of getting seriously ill as they haven't encountered the virus before and lack immunity. Experts recommend vaccinating all children aged 6 months to 23 months to prevent complications.
A nasal spray flu vaccine has been shown to be effective in preventing acute respiratory illness in all age groups. The vaccine was found to be particularly effective in preventing natural influenza A (H1N1) infection among children aged 5-9 years during the 2000-2001 epidemic.
Research found a 10-20% point gap in vaccination rates between blacks and whites, even after adjusting for socioeconomic factors. The study suggests that culturally appropriate messages and additional resources are needed to improve flu vaccination rates among underserved communities.
A study found that patient and doctor attitudes play a crucial role in influenza vaccination rates among older adults. A vaccination-friendly culture at veterans' hospitals exceeded the national goal of 90%, highlighting the importance of promoting preventive measures.
St. Jude experts highlight US vaccine production inadequacies and antiviral drug scarcity in responding to an outbreak, emphasizing the need for new technologies, international cooperation, and rapid testing.
A study by Ohio State University researchers found that even mild depression in caregivers can lead to increased inflammation, which is associated with various age-related illnesses. Chronic inflammation has been linked to declines in physical function and an increased risk of mortality.
A study published in the Proceedings of the National Academy of Sciences found that individuals with greater activity in the left side of the prefrontal cortex had a stronger immune response against disease. The researchers measured brain activity and immune function in 52 individuals between 57-60 years old, and found a positive corre...
Researchers created a technique using validation sets to verify epidemiological data, enhancing vaccine effectiveness studies. This approach helps address reporting bias and improves the reliability of many vaccine research outcomes.
The revised standards recommend systems to remind physicians and patients of immunization due dates, regular monitoring of immunization rates, and financial aid for those who cannot afford vaccination costs. These strategies aim to improve childhood and adult immunization coverage.
A recent study published in the Canadian Medical Association Journal investigated the effects of a Chlorella-derived dietary supplement on immune function and influenza vaccination. The results showed no significant increase in antibody response to the flu vaccine overall, although some increase was seen in participants aged 50 to 55.
A new study shows that a derivative of green algae Chlorella pyrenoidosa improves the body's immune response to influenza vaccines. The study found significant increases in antibody responses after supplementation with two different doses of the extract, with no adverse effects reported.
Researchers have identified the crucial elements of the flu virus that activate the body's T-cells, enabling a new type of vaccine to be developed. This breakthrough could provide long-term protection against future pandemics.
A novel flu vaccine developed by The Wistar Institute has generated a strong antibody response in mice, offering hope for a more stable and effective vaccine. The vaccine targets a stable region of the virus, potentially providing long-term protection against flu strains.