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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Gains in access to antiretroviral treatment come with some costs

In Ethiopia, the scale-up of antiretroviral treatment has achieved remarkable success in expanding access to treatment and HIV counseling and testing. However, HIV prevention interventions and managing chronic care patients are lagging behind. Task shifting to health officers and workers is credited with these successes, but urgent att...

Meta Quest 3 512GB

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CDC recognizes UCSF's research as critical to HIV prevention

UCSF's Positive Choice: Interactive Video Doctor and Healthy Living interventions have been selected by the CDC for their effectiveness in reducing HIV risk behaviors. These programs address crucial aspects of living with HIV, including stress and coping, transmission risk behaviors, and adherence to medication regimens.

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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Risky behaviors must change for HIV prevention to have any chance of success

To reduce HIV transmission, radical behavioral change is necessary, involving a range of strategies including increasing HIV knowledge, decreasing risky behaviors, and providing access to treatment. The authors emphasize the need for sustainable commitment and proper resources to implement these prevention strategies.

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SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Mouse model shows potential efficacy of HIV prevention strategy

Researchers have developed a new laboratory mouse model that can be used to test the efficacy of pre-exposure antiviral drugs to prevent HIV infection. The BLT mice have human blood cells, liver, and thymus tissue, making them susceptible to vaginal infection with HIV.

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The release of new data from the HVTN 502 HIV vaccine study

The new analyses revealed that the vaccine showed no measurable efficacy, and among individuals with background immunity to the adenovirus vector, there were more HIV infections in the vaccinees as compared to those in the placebo group. The STEP data will continue to be analyzed to better understand these results.

Male circumcision for HIV prevention and more

A recent study suggests that adult male circumcision could help prevent HIV transmission in the US, particularly among heterosexual couples. However, the effectiveness of circumcision in reducing HIV risk among men who have sex with men (MSM) is uncertain due to limited data and potential biases.

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Scaling up HIV prevention programs is cost effective

Researchers found that each doubling of a program's scale can reduce costs by around a third, making it a cost-effective strategy to prevent more HIV infections. Larger prevention programs use money more efficiently than smaller ones, with some large programs being ten times more efficient.

Larger HIV prevention programs are cheaper

A recent study published in BMC Health Services Research found that larger HIV prevention programs in low and middle-income countries can reduce unit costs of prevention services by up to a third. By rapidly scaling up well-run existing programs, the study suggests that more HIV infections may be averted.

Partner reduction is pivotal for HIV prevention

A new approach to HIV prevention focuses on reducing partners, with early evidence from Uganda and Kenya showing a decline in HIV incidence among men. The strategy is seen as a crucial step towards reversing the epidemic, particularly in regions where partner reduction has been successful.

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Tailored HIV-prevention program effective for Latino youth

A tailored HIV prevention program was found to decrease risky sexual behavior among Latino adolescents, increasing condom use and abstinence. The program incorporated aspects of Latino culture into sexual health education messages, resulting in significant reductions in unprotected sex and multiple partners.

Prisoners should have access to proven HIV prevention methods

A recent study highlights the urgent need for consistent HIV prevention methods in prisons, despite international guidelines recommending similar healthcare standards. Experts argue that mass incarceration of non-violent drug-offenders needs review and should prioritize public health over punitive policies.

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HIV prevention efforts have curbed the US AIDS epidemic

A study estimates that US HIV prevention efforts saved between 204,000 to 1.585 million lives and resulted in cost savings of at least $11 billion since the onset of the epidemic, with a cost per infection prevented ranging from under $50,000 to $6,400.

Community building reduces young gay men's HIV risk behavior

A community-based intervention implemented in Albuquerque from 1997-98 found that young gay men reported a 12% decrease in unprotected anal intercourse, reversing baseline increases. The study suggests that empowering communities to establish healthy environments with peer support can effectively reduce HIV risk behavior.

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STD risk may be greater for internet sex seekers

A new study suggests that people who seek sex partners online are at a greater risk of acquiring sexually transmitted diseases (STDs) and HIV. The survey found that online sex seekers were more likely to have had previous STDs and had more partners than those who did not use the internet to solicit sex.

US AIDS cases, deaths, and HIV infections appear stable

Despite new treatments extending lives of individuals with HIV, the overall shortfalls in AIDS treatments are becoming apparent. The US data shows a stabilization in AIDS cases and deaths diagnosed each quarter since July 1998, with roughly 4,000 AIDS deaths and 10,000 AIDS cases diagnosed annually.

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Treatment difficult for HIV-infected street youth

A study of 700 street youth found that geographic mobility and high-risk behaviors contributed to the spread of HIV among young people. The majority of those infected were male, aged 23-25, with high levels of unprotected sex, prostitution, and intravenous drug use.

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GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Preventing AIDS In Women Crack Users

Researchers studied 1,200 female crack users, finding that exchangers were four times more likely to have been in substance abuse treatment and twice as likely to be homeless. The study aims to develop effective HIV prevention measures targeting women at risk of exchanging sex for drugs.

Simplified Therapy To Prevent TB Proven Effective In Developing Countries

A simplified regimen of twice-weekly isoniazid preventive therapy for six months or rifampicin and pyrazinamide for two months was found to be effective in preventing active tuberculosis in HIV-infected individuals. Higher compliance with treatment was observed among those who received the shorter course of treatment.

Short-Course TB Prophylaxis Effective In HIV-Infected Individuals

A two-month course of therapy is an effective alternative to the year-long regimen for preventing active tuberculosis in HIV-infected individuals. The study found that fewer deaths occurred among patients in the two-drug arm, with improved treatment compliance compared to the one-drug arm.

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Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

NIAID Evaluates N-9 Film As Microbicide

A recent study by the National Institute of Allergy and Infectious Diseases (NIAID) found that women using N-9 film with condoms had an overall rate of HIV transmission of 6.7%, significantly lower than previously estimated rates in this population.

Vaccination Can Prevent Death And Disease Without Killing A Virus

Researchers at the University of Wisconsin Medical School have shown that vaccination can reduce or prevent fatal immune responses to a virus in mice, even though the virus continues to live in the animals. This finding has important implications for treating chronic and latent viral infections such as AIDS, herpes, and tuberculosis.