Researchers from Boston University School of Medicine recommend that women on hormone therapy continue their treatment before annual mammogram screenings. The increase in breast density due to hormone therapy is unlikely to mask early cancer detection, making it unnecessary to stop treatment prior to screening.
SourceBoston University School of Medicine·JournalMenopause The Journal of The North American Menopause Society·DateSep 28, 2009
Research identifies women who entered menopause recently may be at higher risk of joint pain caused by breast cancer drugs. Electro-acupuncture proves helpful for alleviating symptoms, improving fatigue and anxiety.
SourceUniversity of Pennsylvania School of Medicine·JournalCancer·DateSep 28, 2009
A new study found that hormone therapy for prostate cancer increases the risk of developing heart problems, including coronary heart disease and heart attacks. The study suggests that doctors should consider heart-related side effects when prescribing endocrine therapy and refer patients to a cardiologist before starting treatment.
SourceECCO-the European CanCer Organisation·DateSep 22, 2009
A large study on adjuvant endocrine treatment for postmenopausal, hormone-positive breast cancer found that patients who continued to take exemestane or tamoxifen had significantly better outcomes than those who stopped taking the medication. Non-compliance was higher in countries with less stringent guidelines.
SourceECCO-the European CanCer Organisation·DateSep 21, 2009
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
A large trial found that hormone replacement therapy (HRT) increases the risk of death from lung cancer, especially non-small-cell lung cancer. Women taking HRT were 71% more likely to die from lung cancer than those on placebo, with higher risks also seen in current and long-term past smokers.
New research from Purdue University raises concerns about estrogen supplements claiming to improve bone health in postmenopausal women. While some plant-derived isoflavones show modest effects, many supplements lack efficacy or are less effective than current treatments for osteoporosis.
SourcePurdue University·JournalJournal of Endocrinology and Metabolism·DateSep 2, 2009
A new molecule has been discovered that can treat type 2 diabetes and reduce weight gain by activating the protein TGR5. The study found that INT-777, a selective TGR5 activator, increases GLP-1 secretion and energy expenditure, leading to improved blood sugar control and weight loss.
SourceEcole Polytechnique Fédérale de Lausanne·JournalCell Metabolism·DateSep 1, 2009
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Men with coronary artery disease-induced congestive heart failure or heart attack who receive hormone therapy before or along with radiation therapy for prostate cancer have a higher risk of death, according to a study. However, in men without comorbidities, hormone therapy was not associated with an increased risk of all-cause mortality.
Research by Christopher Li and colleagues found a more than four-fold increased risk of ER-negative second cancers among breast cancer survivors taking long-term tamoxifen. The study confirms earlier findings suggesting a link between tamoxifen use and increased risk of aggressive second breast cancer.
SourceFred Hutchinson Cancer Center·JournalCancer Research·DateAug 25, 2009
The PLOS Medicine journal has made all 1500 ghostwriting documents publicly available, revealing a coordinated campaign by Wyeth and medical writing companies to promote hormone drugs. The editors call for action to eradicate ghost-writing, including retraction of papers and investigation by academic institutions.
A recent study found that low-dose estrogen treatment can stop disease progression in patients with metastatic breast cancer, with 87% of those without PET flare reactions showing no response. The treatment was also well-tolerated, with fewer severe side effects compared to high doses.
A new study found that denosumab significantly increased bone density at all monitored sites and reduced new vertebral fractures by 62% in men receiving androgen-deprivation therapy for prostate cancer. The treatment also showed improvements in bone density at the radius, one of the bones in the forearm.
SourceMassachusetts General Hospital·JournalNew England Journal of Medicine·DateAug 11, 2009
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A two-week course of erythropoietin injections has shown promising results in preventing brain damage in oxygen-deprived newborns. The treatment, which can be started up to two days after birth, improves the prognosis and reduces side effects compared to cooling.
SourceUniversity of Gothenburg·JournalPEDIATRICS·DateAug 11, 2009
Oral sodium clodronate reduces death by 23% and increases overall survival to 30% at 5 years for patients with advanced prostate cancer. However, in men with localized disease, clodronate shows no improvement in overall survival.
SourceThe Lancet_DELETED·JournalThe Lancet Oncology·DateAug 10, 2009
Studies found that botanicals were safe, but did not have a significant effect on reducing hot flashes or improving cognitive function compared to hormone therapy. The studies enrolled over 150 women and followed them for 12 months.
SourceUniversity of Illinois Chicago·JournalMenopause·DateAug 6, 2009
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A new study by Louis Potters and colleagues found that permanent prostate brachytherapy is an effective treatment option for younger patients diagnosed with prostate cancer, with success rates comparable to older patients. The study analyzed data from 2,119 patients and showed that age didn't impact the long-term therapeutic outcome of...
SourceNorthwell Health·JournalThe Journal of Urology·DateAug 3, 2009
Researchers at Northwestern University use nanodiamonds to deliver insulin for wound healing, demonstrating a method for localized release of therapeutic proteins. The nanodiamond-insulin clusters show promise for wound-healing applications and could be integrated into various treatments.
SourceNorthwestern University·JournalBiomaterials·DateJul 27, 2009
Researchers at Thomas Jefferson University identified DACH1 as a protein that prevents cancer cell proliferation by repressing estrogen receptors in ER+ breast cancer. As DACH1 expression decreases in breast cancer, estrogen receptor presence increases, suggesting its potential as a therapeutic target.
SourceThomas Jefferson University·JournalCancer Research·DateJul 15, 2009
Women taking hormone therapy have a 38% increased risk of ovarian cancer, with risks increasing by 44% for epithelial tumors. The absolute risk is approximately 1 extra ovarian cancer for every 8,300 women taking hormone therapy annually.
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Researchers found that curcumin delays tumor development and reduces multiplicity of progestin-accelerated tumors. Curcumin inhibits VEGF secretion from breast cancer cells, potentially reducing breast cancer risk for women exposed to hormone replacement therapy.
SourceUniversity of Missouri-Columbia·JournalMenopause·DateJul 13, 2009
Sexual medicine experts focus on treating causes of sexual dysfunction beyond physical issues, exploring relationship dynamics and hormonal imbalance. New treatments and options for women and men are being developed to address complex sexual health needs.
SourceMedical College of Georgia at Augusta University·DateJun 22, 2009
Researchers discovered a potential new treatment for muscle atrophy, a debilitating condition characterized by loss of muscle mass and function. Des-acyl ghrelin, an appetite-stimulating hormone, shows anti-atrophic activity on skeletal muscle in mice with muscular atrophy.
Versartis has presented positive preclinical data on its two product candidates, VRS-317 and VRS-826, which have the potential to extend half-life of drugs. The company's compounds have shown in vivo potency equal to daily hGH and sustained plasma levels without toxicity.
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A new study suggests that natural hormone angiotensin 1-7 may help treat the metabolic syndrome, a cluster of risk factors increasing heart disease and diabetes risk. Angiotensin 1-7 lowered fasting insulin levels and improved triglycerides and blood sugar in fructose-fed rats.
A new study found that hormone therapy combined with physical activity significantly reduces belly fat and body fat percentage in postmenopausal women. The research, which included 34 healthy women, showed that active women had lower waist measurements and better cholesterol levels after 4 months of hormone replacement therapy.
A recent study found that hormone therapy can alter prostate tumor properties, making them more aggressive and prone to metastasis. The treatment reduces male sex hormone production, but also increases levels of proteins enabling cancer cells to spread.
SourceUniversity of Gothenburg·JournalThe Prostate·DateJun 10, 2009
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers discovered that a nicotine receptor inhibitor, α-CbT, can double survival time in non-small cell lung carcinoma mice. The treatment showed significant antitumor activity by inducing apoptosis and had limited toxic effects on unaffected cells.
SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateJun 8, 2009
A new study found that taking a short break from postmenopausal hormone therapy does not lower the risk of false-positive mammogram results. However, it may help reduce breast density, making tumors harder to detect on X-rays.
SourceGroup Health Research Institute·JournalAnnals of Internal Medicine·DateJun 1, 2009
Researchers used PET scanning to assess estrogen receptor positive breast cancer patients' response to standard aromatase inhibitor therapy after just two weeks. The results showed significant declines in glucose analogue FDG values, similar to earlier studies using needle biopsies.
A new study reveals that nearly one in four African American women with late-stage breast cancer refuse chemotherapy and radiation therapy. The authors emphasize the need for improved healthcare access and education to encourage treatment adherence. Further research is necessary to understand the factors contributing to this disparity.
SourceAmerican Cancer Society·JournalCancer·DateMay 22, 2009
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
A recent study published in Epidemiology found that hormone replacement therapy does not increase breast cancer risk for women with or without a family history. The research analyzed data from the Women's Health Initiative randomized trial and suggests that estrogen sensitivity may not be the causal pathway based on family history.
SourceUniversity of Rochester Medical Center·JournalEpidemiology·DateMay 19, 2009
A study by Duke University Medical Center found that only 64% of low-income women with hormone receptor-positive breast cancer filled any prescriptions for hormonal therapy within 12 months after diagnosis. The researchers also discovered that 40% of the women stopped taking their medication regularly, and 20% stopped using it altogether.
SourceDuke University Medical Center·JournalJournal of Clinical Oncology·DateMay 18, 2009
A proteomic analysis of 50 participants from the Women's Health Initiative hormone replacement therapy trial reveals estrogen upregulates proteins involved in major body processes. The study found changes in serum levels of proteins affecting coagulation, metabolism, osteogenesis, and blood vessel morphogenesis.
SourceBMC (BioMed Central)·JournalGenome Medicine·DateApr 28, 2009
A new analysis finds that prostate cancer patients who undergo testosterone-lowering therapy are at higher risk of bone fractures and heart-related deaths. The study highlights the need for preventive measures and careful health scrutiny to mitigate these risks.
SourceAmerican Cancer Society·JournalCancer·DateApr 27, 2009
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
A large study found that hormone therapy use was associated with a 28% lower incidence rate of colorectal cancer in older women. However, the mechanisms behind this protective effect are still unclear. The study also found no associations between hormone use and specific molecular markers or DNA methylation patterns.
Early diagnosis and treatment of achondroplasia's manifestations can produce better outcomes for patients later in life. This includes addressing stenosis of the foramen magnum and thoracolumbar kyphosis, which can cause developmental delays and spinal deformities.
SourceAmerican Academy of Orthopaedic Surgeons·JournalJournal of the American Academy of Orthopaedic Surgeons·DateApr 1, 2009
A new study published in Menopause: The Journal of the North American Menopause Society found that transdermal estrogen delivery may not increase the risk of blood clots in postmenopausal women, unlike oral delivery. The study suggests that transdermal HT delivery may be a safer alternative for some women.
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalMenopause·DateMar 26, 2009
Researchers are developing new classes of anti-androgen therapies, including MDV3100, abiraterone, and OGX-427, to treat castrate-resistant prostate cancer (CRPC). Angiogenesis inhibitors like bevacizumab target vascular endothelial growth factor (VEGF) to slow tumor growth and metastasis.
New research suggests kisspeptin can activate release of sex hormones in women with infertility, leading to increased luteinising hormone production. The study found a 48-fold increase in LH and 16-fold increase in FSH in women treated with kisspeptin compared to controls.
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers found that estrogen activates genes encoding nitric oxide synthases, leading to enhanced lung function and reduced ventilation support needs. Estrogen also prevented low blood pressure and closed the ductus arteriosus, a shunt that connects the pulmonary artery to the aorta.
SourceUT Southwestern Medical Center·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateMar 12, 2009
A study published in Journal of Psychopharmacology found that MDMA, a pharmaceutical version of Ecstasy, can enhance the effectiveness of exposure therapy for PTSD. By increasing oxytocin levels and reducing fear responses, ecstasy may help patients overcome traumatic memories and reduce stress.
SourceSAGE Publications UK·JournalJournal of Psychopharmacology·DateMar 9, 2009
Researchers used a six-gene model to stratify patients with castration-resistant prostate cancer, predicting survival and accuracy rates. The study found the model accurate in predicting low-risk patients' survival and high-risk patients' mortality.
A new study found that women with a longer fertile lifespan and more years of exposure to their own sex hormones may be protected from Parkinson's disease. Women with four or more pregnancies were at greater risk of developing the disease compared to those with fewer pregnancies.
SourceAmerican Academy of Neurology·JournalNeurology·DateFeb 25, 2009
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A new study found that women with a longer fertile lifespan, resulting in higher levels of naturally produced estrogen, had a lower risk of developing Parkinson's disease. However, hormone therapy did not offer protection against the disease, and may even have harmful neurological effects.
A new study by Stanford researchers finds that combined estrogen plus progestin hormone therapy increases the annual risk of breast cancer in postmenopausal women, with a doubling of risk after five years. Stopping hormone therapy can quickly reduce this risk, as observed in a follow-up study.
SourceStanford Medicine·JournalNew England Journal of Medicine·DateFeb 4, 2009
Primary ovarian insufficiency is a menopause-like condition affecting girls and young women, characterized by loss of menstrual periods, infertility, and hot flashes. A comprehensive plan provides recommendations for diagnosis and treatment, including hormone replacement therapy and counseling.
SourceNIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development·JournalNew England Journal of Medicine·DateFeb 4, 2009
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A new study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that growth hormone treatment after weight loss surgery reduces lean body mass and skeletal muscle mass losses. Researchers discovered that short-term growth hormone treatment during a standardized diet and exercise program increased l...
SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateFeb 3, 2009
A study published in JAMA found that using N-terminal brain natriuretic peptide (BNP) to guide therapy did not improve overall clinical or quality of life outcomes for older patients with heart failure. In contrast, the study showed improved survival rates and reduced hospitalizations for patients receiving BNP-guided therapy.
A Canadian/U.S. research team has reported a therapeutic model exploiting the natural dynamics of the 'fight or flight' system to stimulate recovery from chronic stress disorders. The HPA axis dysfunction may become chronic if driven far from its natural homeostatic rest point, leading to disorders like CFS, depression, and PTSD.
SourcePLOS·JournalPLOS Computational Biology·DateJan 22, 2009
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Key epigenetic abnormalities in endometriosis have been identified, including the presence of aromatase, which produces excessive estrogen in affected tissue. Aromatase inhibitors are now being tested for treatment options.
SourceNorthwestern University·JournalNew England Journal of Medicine·DateJan 16, 2009
Experts warn that while hormonal contraceptives may be safe for many women, gaps in knowledge remain. The article highlights the need for further research on low-dose oral contraceptives and alternative forms of contraception for high-risk individuals.
SourceCedars-Sinai Medical Center·JournalJournal of the American College of Cardiology·DateJan 13, 2009
Two new studies link hormone therapy to reduced brain volume in critical memory areas, accelerating loss of cognitive function in postmenopausal women. Researchers found no correlation between hormone therapy and increased brain lesions, contradicting previous hypotheses.
SourceAtrium Health Wake Forest Baptist·JournalNeurology·DateJan 12, 2009
New studies have found a link between hormone therapy and brain shrinkage in postmenopausal women, with smaller brain volumes in areas involved in thinking and memory skills. However, hormone therapy was not linked to an increase in small vascular lesions or 'silent strokes' that are often the first sign of cerebrovascular disease.
SourceAmerican Academy of Neurology·JournalNeurology·DateJan 12, 2009
Researchers have discovered a key difference in hormone receptors on prostate cancer cells in patients who no longer respond to hormone deprivation therapy. The finding, published in Cancer Research, could lead to new targets for treating prostate cancer and monitoring disease progression.
SourceJohns Hopkins Medicine·JournalCancer Research·DateDec 31, 2008
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
In a phase III trial, combining endocrine treatment with radiotherapy reduced prostate cancer mortality by half compared to endocrine treatment alone. The study found significant superiority of the combined treatment over hormone therapy alone in reducing prostate cancer-specific mortality and overall survival.
Studies show hormone supplements, such as estrogen-progestin and letrozole, can reduce breast cancer mortality risk by up to 63% and improve overall survival. Meanwhile, tamoxifen is found to be superior for quality of life measures, with patients paying a price in quality of life when switching from anastrozole.
SourceAmerican Association for Cancer Research·DateDec 12, 2008
Researchers are studying new treatments, including zoledronic acid, aromatase inhibitors and monoclonal antibodies, with encouraging results. Exemestane has been shown to be more effective in postmenopausal women than current treatment with tamoxifen.
SourceAmerican Association for Cancer Research·DateDec 11, 2008
A study of over 140,000 babies found late preterm births are associated with increased risk of cerebral palsy and mental retardation. The research highlights the need for early neurological assessments and cautious approach to elective deliveries before 39 weeks.
SourceElsevier Health Sciences·JournalThe Journal of Pediatrics·DateDec 11, 2008
A study found that estrogen therapy can stop the growth of tumors or cause them to shrink in about a third of women with metastatic breast cancer that has developed resistance to standard estrogen-lowering therapy. The high-dose regimen had significant side effects, while the low-dose regimen was well tolerated.
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
A recent study led by Massachusetts General Hospital researchers found that hormone therapy for prostate cancer does not appear to increase the risk of death from cardiovascular disease. However, other adverse effects such as diabetes and heart disease still exist, necessitating careful treatment strategies.
SourceMassachusetts General Hospital·JournalJournal of Clinical Oncology·DateDec 10, 2008