Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
The Icahn School of Medicine at Mount Sinai is part of a new NIH Stroke Research Network aiming to expedite stroke clinical trials and build expertise in stroke prevention, treatment, and rehabilitation. The school will receive a $1.3 million grant to develop a collaborative research infrastructure.
Researchers at the University of Pittsburgh have discovered a unique immune avoidance mechanism used by a deadly mosquito-borne virus to suppress human immunity. The discovery could lead to the development of vaccines and treatments for eastern equine encephalitis virus, which has a 30-70% fatality rate.
A systematic review found that non-specialist providers can deliver effective treatments for children with intellectual disabilities or lower-functioning autism spectrum disorders. The studies showed improvements in developmental, behavioral, and family outcomes with various psychosocial interventions.
A study found that nonsurgical periodontal treatment did not result in improved glycemic control in people with type 2 diabetes and chronic periodontitis. Despite improvements in clinical measures of chronic periodontitis, the treatment had no impact on HbAlc levels.
A novel role for S100β has been identified as a biomarker for delirium duration in critically ill patients, which may have implications for refining treatment in intensive care units. Delirium duration is associated with increased mortality rates, and higher levels of S100β on day 1 or day 8 are linked to longer delirium duration.
Researchers found that using hot baths to raise body temperature and worm eggs to stimulate immunoregulatory factors may attenuate symptoms of autism. The study suggests that inflammation may contribute to the disorder, and these novel approaches could be future treatment options.
The NIH Stroke Trials Network, or NIH StrokeNet, aims to address the three prongs of stroke research: prevention, treatment, and recovery. The network will fund and manage 25 regional centers, each with a team representing every medical specialty needed for stroke care.
A new report by the International Osteoporosis Foundation warns that Hong Kong's rapidly ageing population will lead to a significant increase in hip fractures, resulting in severe disability and early deaths. The report recommends prioritizing osteoporosis treatment and prevention to mitigate this growing health problem.
Professor Len Harrison has been awarded the JDRF Australia Lifetime Research Achievement Award for his groundbreaking work on improving treatments for people with type 1 diabetes. His research aims to prevent or delay the onset of the disease, bringing hope for better therapies and treatments.
Researchers discover embolic material, polyvinylpyrrolidone (PVP), at site of fatal brain hemorrhages occurring days after aneurysm treatment. PVP is suspected to have traveled through vasculature from PED delivery site to location where hemorrhage occurred.
The emergence of fertility loans has raised ethical concerns as doctors market them to patients with potential financial ties to lenders. Experts argue that this practice may exacerbate the anguish of infertility by promoting unsuccessful interventions.
A new study published in The Lancet has found that compression stockings are a cost-effective treatment for venous leg ulcers, reducing recurrence and nurse visits. While some patients may not prefer to wear the stockings, they offer improved value for money for the NHS compared to traditional bandages.
Researchers at Western University found that neurofeedback training can alter key brain networks linked to post-traumatic stress disorder (PTSD), leading to improved subjective well-being. The study used a combination of EEG and fMRI techniques to measure changes in brain activity and connectivity after a 30-minute neurofeedback session.
A study using MRI technology found that veterans with mild traumatic brain injury (MTBI) caused by blasts have long-term brain differences, including changes in white matter structure. This suggests a potential link between blast exposure and ongoing cognitive symptoms in veterans.
Researchers have discovered a promising new treatment that can help people with spinal cord injuries walk better. The study involved 19 participants who received short periods of breathing low oxygen levels, resulting in improved walking speed and endurance.
Studies have shown that laser treatment is effective in reducing scar height and redness, with a high success rate of 70% in treating both hypertrophic scarring and keloids. The use of specific lasers, such as the 585/595 nm pulsed-dye laser, has also been found to be particularly effective.
A genetic mutation in ADCK4 has been identified as a cause of steroid-resistant nephritic syndrome. Patients with this mutation show reduced CoQ1 levels and decreased mitochondrial respiration. Treatment with CoQ10 may improve outcomes for affected individuals.
A new study published in PLOS ONE has found that steroid injections given to pregnant women before premature birth may increase the child's risk of later behavioral and emotional difficulties. The study of over 6,000 children revealed poorer scores on general mental health at ages eight and 16, and a higher likelihood of symptoms of ADHD.
A new stroke research network is forming in Chicago, bringing together top medical centers to develop and execute high-quality clinical trials for stroke prevention, treatment, and recovery. The consortium aims to rapidly advance therapies and reduce death and disability from the disease.
A new study found that hospital management of patients who self-harm in England has barely changed over the past 10 years, with 40% of those attending hospital not receiving a specialist psychosocial assessment. The treatment received also varied according to where they lived, suggesting a postcode lottery was still in operation.
Researchers at the University of Iowa found that maintaining a direct channel of communication between patients and primary doctors is crucial to success. Patients in regular contact with their primary physicians are most satisfied with their care, according to a new study.
Researchers at Tel Aviv University demonstrate hyperbaric oxygen therapy can revive brain functions and improve life quality for mild TBI patients. The treatment improved cognitive function, memory restoration, and language use, offering a new hope for millions of victims.
A new study by Duke University professor E. Jane Costello found that more than half of adolescents with psychiatric disorders receive no treatment. Treatment rates vary greatly depending on the disorder and provider, with teens suffering from phobias or anxiety disorders being the least likely to be treated.
A national study published in NEJM found that comprehensive medical therapy is as effective as renal stenting in preventing clinical events for patients with renal artery stenosis. The study, led by Rhode Island Hospital researchers, involved over 947 participants and followed them for up to seven years.
Researchers suggest annexin A5 may have therapeutic potential for treating sepsis, improving cardiac function and survival rates in mice. The study's findings could apply to multiple organs affected by sepsis.
A new study found that butyrate, a fatty acid produced by gut bacteria, induces the production of regulatory T cells in the gut, boosting the immune system. This discovery supports the use of butyrate as therapy for inflammatory bowel diseases like Crohn's disease and may lead to personalized preventive medicine.
Researchers at Wayne State University have made a breakthrough discovery in the inflammatory stress mechanism driving rheumatoid arthritis. A specific IRE1a inhibitor was identified to prevent arthritis in animal models, offering new hope for treating this autoimmune disease.
A new Case Western Reserve University study examines how ruptures in the therapeutic relationship between therapist and client can damage a patient's treatment outcome for PTSD. Researchers found that repairing these ruptures can have positive effects on treatment outcomes, while unresolved ruptures predict poorer outcomes.
Researchers have found that miR-137 is downregulated in the brains and peripheral blood of post-stroke depression patients. Injection of a miR-137 antagonist into the brain ventricles of post-stroke depression rats improved behavioral changes, suggesting that miR-137 suppresses Grin2A protein expression through binding to its mRNA.
A new analysis examines factors affecting integration of mental health and substance abuse treatment services with medical care at community health centers. Health centers were more likely to offer behavioral health services if they were larger or located in areas with more psychiatrists and psychologists per capita.
Percutaneous repair of paravalvular prosthetic regurgitation can mitigate known risks associated with increases in implanted valves, particularly in patients at high-risk of cardiac surgery. The technique has shown durable symptom relief and reduced mortality rates in selected patients.
Research from North Carolina State University found that weight loss in one partner can bring couples closer if both partners are supportive of healthy changes. However, resistance to change can lead to negative effects on the relationship. Couples where both partners were receptive to weight loss reported more positive interactions an...
A recent study found that African-American women and non-white women have lower knowledge about urinary incontinence and pelvic organ prolapse compared to white women. The study suggests that culturally sensitive educational interventions are urgently needed to address these disparities.
Researchers surveyed ICU physicians in five ICUs and found that patients waiting for care were negatively affected by futile treatment. The study revealed that a significant number of patients waited for over four hours or more before receiving care, with some spending extended periods waiting due to lack of ICU capacity.
A recent Mayo Clinic survey found that uterine fibroids significantly impact the quality of life and workplace performance of women, with African-American women experiencing more severe symptoms and delayed diagnosis. The study highlights the need for better treatment options and increased awareness about this common public health issue.
A new study by London School of Hygiene & Tropical Medicine and University of York reveals that foreign private patients bring in nearly a quarter of total private income to NHS trusts. Meanwhile, UK residents travel abroad for treatment at an estimated 63,000 times per year.
A large-scale study found that two new psychotherapeutic methods and a specialized form of standard psychotherapy can effectively treat anorexia nervosa in adults. Patients continued to show significant weight gains even after therapy concluded, with improved BMI and mental health outcomes.
A large-scale trial found that cognitive behavioral therapy (CBT) significantly reduced symptoms of health anxiety in medical patients, with improvements sustained at 2 years. The treatment was delivered by non-specialist staff with minimal training and cost-effectively reduced healthcare costs.
A study of over 67,000 Canadians found that depression is nearly twice as prevalent among migraine sufferers as the general population, particularly among younger women and those with difficulty performing daily activities. The study also highlights a higher risk of suicidal ideation among young migraineurs.
Researchers discovered that Neanderthals used toothpicks to alleviate periodontal disease pain, revealing a unique example of ancient palliative medicine. The study, published in PLOS ONE, analyzed toothpicking marks on a Neanderthal fossil and found evidence of maxillary porosity, characteristic of the disease.
Insomnia affects up to 54% of US military personnel and veterans since 2001, with deployment-related stressors contributing to chronic sleeplessness. Behavioral interventions like cognitive-behavioral therapy show promise in reducing insomnia's effects.
A three-way partnership between UCLA, USC, and UC Irvine will form the Los Angeles–Southern California Regional Coordinating Center to address stroke prevention, acute therapy, and recovery. The network will perform five to 10 clinical trials and educate fellows in stroke translational research.
Three new studies highlight the importance of seeking treatment for sleep illnesses and aiming for 7-9 hours of sleep per night. Results show increased mortality risks, motor vehicle crashes, and poor self-rated health among individuals with untreated obstructive sleep apnea (OSA).
A study by University of Alberta researcher Deryk Beal found that children who stutter have less grey matter in brain regions responsible for speech production. This discovery highlights the importance of early treatment approaches like those pioneered by the Institute for Stuttering Treatment and Research.
A new study published in Neurology found that stroke treatments and prevention are not effective enough to improve quality of life for people who experience a stroke. The study suggests that strokes take nearly three out of five quality years off a person's life, depending on the severity of the stroke.
Pediatric atrial fibrillation is a rare but serious condition with substantial symptoms and a high recurrence rate. Researchers found that nearly 40% of patients experienced recurrence, with significant complications in three cases.
A study found that binge drinking slows bone healing by impairing the formation of hard bony tissue and recruiting stem cells to the injury site. Alcohol also increases oxidative stress, which can lead to weaker bones.
A new MRI technique has been developed to detect Fabry disease, a genetic condition that affects the heart, brain, and nerves. The T1 mapping test can identify microscopic changes in the heart muscle structure that are not visible on regular images, allowing for early detection and treatment.
Scott Hansen, a Scripps Research Institute scientist, has won the NIH New Innovator Award to study mechanosensation, particularly touch and hearing. The award provides $2.8 million in research funding over five years to explore the molecular mechanisms behind sensing touch.
A team of IUPUI researchers will investigate the impact of staff burnout on mental health treatment and outcomes, implementing an intervention program that incorporates traditional stress-reduction techniques and cognitive behavioral practices. The goal is to reduce burnout and improve clinician engagement in patient care.
Researchers at Drexel University are developing a smartphone app to track individuals' patterns of eating and binge-eating behavior, alerting them at risk. A new evidence-based approach to small-group behavioral therapy also aims to equip patients with psychological tools to adhere to standard treatments.
A recent study found that using DVDs, booklets, and health coaches can help patients arrive at an informed treatment decision within their first visit with an orthopaedic surgeon. The study showed a significant increase in patient confidence in knowing what questions to ask their doctor, leading to better shared medical decision making.
Treating strep throat with penicillin can reduce ARF/RHD risk by 70-80%, and including primary prevention in overall strategy is crucial. Global efforts to combat RHD control have shown success through comprehensive strategies involving syndromic treatment, education, and awareness campaigns.
Scientists have developed a portable imaging system that harnesses smartphones to detect individual viruses and determine viral load. This breakthrough enables remote diagnosis and treatment monitoring in resource-limited locations.
A new study found that only 12 out of 92 eligible patients received an implantable cardiac defibrillator after being medically evaluated. The majority who qualified did not receive the treatment, highlighting a need for further analysis to determine why this occurs.
Researchers from UT Arlington used mathematical modeling to simulate foreign-body reactions to implants, finding results consistent with lab tests. The model aims to improve biocompatibility and identify optimal treatments for severe inflammation and fibrotic capsule formation.
A Northwestern University study found that fear memories can be reduced in people by exposing them to the memory over and over again while they slept. This breakthrough potentially offers a new way to enhance daytime treatment of phobias through exposure therapy with a nighttime component.
A new NIH study found that bracing significantly reduces the risk of curve progression and the need for surgery in adolescents with idiopathic scoliosis. Wearing a brace for more than 13 hours per day is associated with success rates of 90-93 percent.
A multi-center study found that wearing back braces significantly reduced the risk of curve progression and the need for surgery in children with adolescent idiopathic scoliosis. Patients who wore a brace more than 13 hours per day achieved success rates of 90-93%.
The National Institutes of Health (NIH) is funding new bird flu vaccine studies to protect against a deadly strain that caused severe disease in China last spring. The study aims to fine-tune the process of creating an effective vaccine, with the goal of preventing future pandemics.