Articles tagged with Vaccination
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at Kanazawa University have identified a new vaccine platform that targets liver cells to induce anti-malaria immunity. The AAV8 vaccine platform was found to be more effective in eliciting a T cell-mediated response in the liver, providing sterile protection against malaria in a murine model.
A new study has shown that a single dose of typhoid conjugate vaccine (TCV) is safe and 84 percent effective in protecting against typhoid in Blantyre, Malawi. The findings are critical as typhoid is an increasing public health threat across sub-Saharan Africa.
Some women report changes in their periods after COVID-19 vaccination, with over 30,000 reports made to the UK's MHRA surveillance scheme. While most changes are short-lived, research into this possible adverse reaction is critical for the success of the vaccination programme.
A new study from La Jolla Institute for Immunology shows that the Moderna COVID-19 vaccine generates durable T cell memory and antibodies, even in people over 70. The researchers found strong CD4+ and CD8+ T cell responses to the vaccine, comparable to those seen in recovered COVID-19 patients.
Researchers have identified the potential of 7HP349 as an oral medication to strengthen the effectiveness of vaccines, particularly for populations that struggle with immunosuppression. The study suggests adding 7HP349 to standard vaccination can improve vaccine efficacy without reformulating the vaccine.
Researchers investigated antibody response to Pfizer-BioNTech vaccine in 117 allogeneic hematopoietic stem cell transplant recipients. The study aimed to assess vaccine safety and immune response in this population. Key findings were not reported in the article.
A two-dose Ebola vaccine regimen has been found to be safe, well-tolerated, and produce a strong immune response in people over 1 year old. The study also supports the use of this regimen for Ebola virus disease prevention in children and adults.
A recent study investigated a COVID-19 outbreak among fully vaccinated residents and healthcare professionals in a French nursing home. The study highlights the importance of vaccination in preventing severe illness but also underscores the limitations of current vaccines.
A national study found COVID-19 vaccines are effective in preventing hospitalizations and emergency department visits caused by the Delta variant. The Moderna vaccine is significantly more effective than Pfizer and Johnson & Johnson, with unvaccinated individuals being 5-7 times more likely to need emergency care or hospitalization.
A new poll shows strong support among older Americans for requiring health care workers to get vaccinated against COVID-19. The survey found that 61% of people aged 50 to 80 believe the vaccine should definitely be required, while an additional 19% think it should probably be required.
A New England Journal of Medicine study found that COVID-19 vaccines are highly effective in preventing hospitalizations, emergency department visits, and intensive care admissions due to the virus. The vaccines provide significant protections for older adults and minorities, who have been disproportionately affected by the virus.
Researchers will examine protective immunity in older adults and assess the duration of immunity against emerging strains of COVID-19. The study aims to inform booster vaccine recommendations for seniors.
Scholars argue that well-done vaccine selfies can encourage others to get vaccinated and share personal stories about the effects of the vaccine. The practice can create a bandwagon effect, highlighting health, joy, and optimism and positively shaping public perception of COVID-19 vaccines.
The COVID-19 vaccine has been shown to have a positive impact on the mental health of US adults, with those receiving the first dose experiencing improvements. A recent study published in PLOS ONE found that the vaccine reduced symptoms of anxiety and depression.
A novel gene-based COVID-19 vaccine leveraging an adeno-associated viral vector platform was highly effective in eliciting neutralizing antibody responses and cellular immunity from a single dose. The vaccine provided near-complete protection against SARS-CoV-2 challenge in nonhuman primates for at least 11 months.
A new study by Columbia University Mailman School of Public Health reveals stark racial, ethnic, and socioeconomic inequities in COVID-19 vaccination rates across neighborhoods in the largest US cities. High-vaccination neighborhoods were predominantly white with fewer people of color, higher incomes, and lower poverty rates.
The Delta variant's ability to evade neutralizing antibodies and its increased infectivity have contributed to its spread, making vaccination and infection control crucial in the post-vaccination era. The variant was found to be more efficient at replicating and spreading than other variants, giving it a selection advantage.
A recent study reveals significant inequities in COVID-19 vaccination rates among the nine largest US cities. The research found that racial and socioeconomic disparities contribute to these disparities.
Researchers found that prior exposure to common cold coronaviruses boosts the body's immune response to SARS-CoV-2, with cross-reactive T cells recognized by the immune system. The study's findings suggest a protective effect against severe disease and improved vaccine efficacy in younger individuals.
A study based on US blood donations found increasing seroprevalence of SARS-CoV-2 antibodies over time, with variations by age, race, and geographic region. Seroprevalence estimates the prevalence of SARS-CoV-2-specific antibodies due to natural infection or vaccination.
A new study from the University of Virginia Health System found that Moderna's vaccine produced higher antibody levels than Pfizer's, especially in older subjects. The researchers caution that measuring antibody levels does not necessarily predict vaccine effectiveness.
A new analysis suggests that the pace of vaccination should directly dictate the lifting of COVID-19 restrictions to boost freedoms and minimize new waves of infection. The study's findings suggest that further severe waves can be avoided if restrictions are lifted no faster than the pace dictated by vaccination progress.
A study of highly vaccinated health workers found that COVID-19 vaccines lost effectiveness in protecting against symptomatic infection by July, with only 65% protection remaining. The emergence of the delta variant and lifting of masking mandates contributed to this decline in vaccine efficacy.
Researchers compared antibody responses in adults receiving Pfizer/BioNTech and Moderna COVID-19 vaccines. The study found differences in antibody responses among young and older adults. Younger recipients showed higher antibody levels after vaccination.
A study found that people who feel their sense of autonomy is unmet by government incentives like vaccine passports are less likely to take the COVID-19 vaccine. The research highlights that public health incentives might affect people's vaccination decisions in unintended ways, potentially undermining herd immunity.
A large-scale UK study confirms that COVID-19 vaccines are effective in reducing severe illness and hospitalisation. The study found that people who received one or two vaccine doses had lower odds of severe disease or hospitalisation than unvaccinated individuals, with a significant reduction in long COVID cases.
Two studies found that breathing humid and salt-enriched air reduced respiratory droplet generation by approximately 50% within 10 minutes. The study suggests this mechanism may contribute to the effectiveness of cotton face masks in reducing COVID-19 incidence and death.
A study found that exposure to SARS-CoV-2-positive household members increased the risk of COVID-19 infection among vaccinated healthcare workers. Household exposure was associated with a higher infectious dose and contagiousness compared to casual or work-related exposure.
A study assessing Pfizer-BioNTech vaccine safety in highly allergic individuals found a lower incidence of severe adverse reactions compared to previously reported rates. The results suggest the vaccine may be a viable option for these high-risk groups.
A study of over 1,000 patients in Philadelphia's emergency departments found that vaccine hesitancy is common among this population, driven by concerns about safety and research. The authors suggest that EDs can play a valuable role in addressing vaccine hesitancy through targeted education and outreach efforts.
A pan-Canadian randomized controlled trial is using digital communication to target common reasons for vaccine hesitancy, including age, language, and education level. Family physicians will receive tailored information to share with patients through email and text message, aiming to improve vaccine uptake.
Research from Drexel University's Autism Institute identifies higher odds of living in residential facilities, receiving outside caregiver services, and having high-risk health conditions among autistic adults, as well as those with intellectual disability and mental health diagnoses. These groups are more likely to contract COVID-19 a...
A survey of 11,000 health care workers found significant racial and ethnic disparities in COVID-19 vaccine hesitancy, with Black workers experiencing a nearly 5-fold increase compared to white workers.
Researchers at Washington University School of Medicine found that COVID-19 vaccination elicited a response in nearly nine out of ten people with weakened immune systems. However, the responses were only about one-third as strong as those mounted by healthy people. Despite this, the discovery is encouraging news for a population at hig...
A small study of 27 children aged 12-15 with neurological conditions found the Pfizer jab's side effects were mild to moderate and cleared up within a week. The vaccination was taken by parents who believed their children were at high risk of COVID-19 disease, highlighting its benefits in vulnerable groups.
A large-scale analysis of Israel's COVID-19 vaccination data found that the Pfizer/BioNTech BNT162B2 vaccine is very safe, with only a few potential side effects. The study also revealed that coronavirus infection poses a much higher risk of serious adverse events compared to vaccination.
The International Vaccine Institute (IVI) has initiated a Phase II/III clinical trial for the Bharat Biotech Chikungunya vaccine candidate BBV87, evaluating its safety and immunogenicity in healthy adults across five countries. The study aims to develop an affordable vaccine with the aim of achieving WHO prequalification.
A US study published in Journal of Health Communication found that emphasizing individual health risks from COVID-19 leads to higher vaccine acceptance among participants. The researchers also discovered that loss framing was slightly more effective than positive gain framing, suggesting cultural and personal factors may play a role.
A survey of mostly African American adults found that vaccine hesitancy was greatest among those aged 18-29, with COVID-related housing insecurity increasing the odds by sevenfold. Younger individuals and those experiencing housing insecurity were more likely to be resistant to vaccination.
A review of expert opinions reveals mixed results for the EU's COVID-19 response, with successes including coordinated vaccine procurement but shortcomings including inconsistent national responses. Experts emphasize the need for strengthened local surveillance systems and improved EU leadership to prevent similar crises.
A new approach has identified T cells in Covid-19 patients, revealing their appearance, number, and activity level against SARS-CoV-2. The study distinguishes between active and dormant T cells, enabling a better understanding of the immune response to the virus.
Experts recommend universities take five steps to minimize COVID-19 risks: on-site vaccinations, delayed re-openings, improved ventilation, effective contact tracing and mask mandates. These measures aim to protect students and staff from the Delta variant and prevent outbreaks.
The early US COVID-19 vaccination campaign prevented nearly 140,000 deaths and 3 million cases of COVID-19. The average state saw a reduction of five fewer deaths from COVID-19 per 10,000 adult residents.
Researchers investigated short-term COVID-19 vaccine reactions in pregnant and lactating individuals compared to those planning pregnancy. The study found that vaccinated pregnant and lactating women experienced fewer severe adverse events than unvaccinated women.
Researchers at Massachusetts General Hospital found that NFL and NCAA games held with limited in-person attendance did not cause an increase in COVID-19 cases. The study suggests that measures such as strict mask use and open air helped prevent the spread of COVID-19 during these events.
A Princeton University and McGill University study found that vaccine nationalism can increase COVID-19 cases and facilitate the emergence of novel variants. Increased vaccine-sharing resulted in reduced case numbers in low-access regions, highlighting the importance of equitable global distribution.
A study found that mRNA vaccine recipients with prior SARS-CoV-2 infection experienced more severe symptoms after vaccination. The study suggests vaccine type may influence symptom severity in individuals with a history of COVID-19 infection.
A CDC mask guidance update in May 2021 ignored realities that left vulnerable communities exposed to increased transmission of COVID-19. The guidance relied on the honor system to ensure unvaccinated individuals wore masks, but experts say this approach was flawed due to lack of verification methods.
A South Australian-developed SARS-CoV-19 vaccine has shown promising results in early animal testing, confirming its safety and effectiveness in preventing COVID-19 lung infection. The vaccine, named COVAX-19, incorporates an adjuvant derived from a plant sugar called inulin.
A new research strategy enhances COVID-19 vaccine effectiveness by providing 'border protection' immunity in the nose, mouth and blood. The approach involves suppressing an enzyme that breaks down both pathogens and immune cells, resulting in a robust antibody response and improved protection against infections.
Researchers investigated SARS-CoV-2 BNT162b2 mRNA vaccine response in cancer patients and healthy controls. The study found that the vaccine's antispike IgG antibody response wanes over time in patients on active anticancer treatment.
This observational study evaluates the concentration of SARS-CoV-2 antibodies in breast milk of lactating women who received mRNA vaccines. The findings suggest a correlation between serum antibody levels and breast milk antibody concentrations.
A study found that vaccination alone cannot stop the pandemic in some scenarios, and non-pharmaceutical interventions (NPIs) are necessary to complement vaccination. The model predicts that the pandemic will end between January 20, 2022, and October 19, 2024, assuming immunity persists for 180 days to 365 days.
Researchers found that a second dose of the Pfizer vaccine, especially in those with previous SARS-CoV-2 infection, dramatically increased virus variant neutralising antibody responses. This additional boost increases potential protection against existing and future variants of concern.
Researchers investigated myocarditis cases in adolescents after Pfizer-BioNTech COVID-19 vaccination and found a significant association. The study used comprehensive cardiac imaging and reviewed the results, highlighting the potential risk of myocarditis in this population.
SK bioscience's GBP510 vaccine candidate has shown promising safety and immunogenic response in Phase I/II clinical trials. IVI will partner with SK on global Phase III trials to accelerate development and WHO approval of the vaccine.
The study suggests that COVID-19 eradication is technically possible due to the availability of safe vaccines, lifelong immunity, and effective government management. However, securing high vaccine coverage and responding quickly to variants are major challenges.
Researchers at Massachusetts General Hospital found that crowding in prisons significantly increases the risk of COVID-19 infections among inmates. The study suggests that policy changes are necessary to protect this vulnerable population and notes that even a small increase in crowding can pose a significant threat.
Researchers evaluated antibody levels after Pfizer/BioNTech vaccine in previously infected and uninfected individuals, finding a significant increase in SARS-CoV-2 spike immunoglobin G antibodies. The study suggests the vaccine effectively boosts immunity in those who have already been infected.
A recent study published in Transplant Infectious Disease found that COVID-19 vaccination provides strong protection against the virus for solid organ transplant recipients, with an almost 80% reduction in symptomatic cases. The study examined data from over 2,150 transplant patients and showed that nearly 70% of vaccinated patients re...