Articles tagged with Vaccination
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Researchers found two new TLR7 gene variants in young, healthy men with severe Covid-19, highlighting the importance of genetic screenings for early intervention. These variants were associated with impaired immune response and increased risk of serious illness, emphasizing the need for preventive vaccination strategies.
A new model incorporates human behavior and fears to predict multiple waves of COVID-19 infections. The 'Triple Contagion' model shows how fear can drive disease resurgence, as people may abandon protective measures prematurely or avoid vaccines due to misinformation.
A new model developed by NYU Tandon School of Engineering researchers provides a data-centric approach to reopening towns and can serve as a blueprint for areas with low vaccine rates. The model shows that increasing access to social gatherings and public transportation at a certain rate supports a safe, rapid reopening.
A new Polish study examines why people refuse vaccination, finding that generalized negative attitudes towards vaccines and confirmation bias play a significant role. Vaccine deniers often attribute negative symptoms to vaccines despite missing evidence of correlation.
Researchers at Mayo Clinic found that wearing masks and maintaining physical distance significantly reduce the spread of COVID-19. The study showed that both disposable paper medical masks and two-layer cloth masks were effective in blocking aerosol particles, with increased distance reducing particle counts to near baseline levels.
A survey of US and NYC parents found that only 49% planned to vaccinate their youngest child, with vaccine hesitancy linked to education level and income. The study highlights the need for targeted information campaigns to improve vaccination uptake among young children.
Göttingen researchers have developed mini-antibodies that efficiently block the coronavirus SARS-CoV-2 and its new variants. The nanobodies bind and neutralize the virus with extreme stability, making them promising agents to treat COVID-19.
A study published in Nature Medicine found that combining different COVID-19 vaccines boosts the immune response by up to ten times. The research team discovered that a combination of AstraZeneca and BioNTech vaccines or double doses of BioNTech vaccination yields better results than a double dose of AstraZeneca vaccine.
Researchers at the University of East Anglia warn that relaxing Covid-19 restrictions prematurely could pave the way for new vaccine-resistant virus mutations. The 'arms race' between humans and the virus continues, with rising cases providing opportunities for it to evolve into more transmissible variants.
Researchers evaluated the safety of a second Pfizer-BioNTech or Moderna COVID-19 vaccine dose in patients who experienced an allergic reaction to the first dose. The study found no significant increase in adverse events, suggesting the vaccines are safe for those with prior allergic reactions.
A multi-hospital analysis of patients who experienced allergic reactions to their first mRNA COVID-19 vaccine dose found that all patients who received a second dose tolerated it without complications. The study suggests it's safe for most individuals to receive a second dose, despite initial concerns.
Researchers developed a mechanical theory to determine the critical force required for needle insertion in soft materials like skin, discovering that tissue toughness and needle radius play crucial roles. The model provides quantitative predictions and may impact future technology like self-administered disposable pads with microneedles.
The AZ HEROES study, led by the University of Arizona Health Sciences, has received a $15 million award from the CDC to continue its research on COVID-19 vaccine effectiveness. The study will expand to include children aged 4 months to 17 years and focus on underserved populations.
A study investigated longitudinal serological and vaccination responses to SARS-COV-2 in dental professionals. The results showed that natural infection with SARS-COV-2 leads to persistent, neutralizing and protective serological responses in over 70% of participants.
Researchers found that older people have lower antibody responses against COVID-19 variants, making them more susceptible to infection. Vaccination still appears effective in preventing severe illness, but promoting vaccinations is crucial to protect the community.
The study found that two-dose mRNA vaccines provided 88% protection against the original SARS-CoV-2 virus, 86% against the Alpha variant, and 77% against the Beta variant. Previous SARS-CoV-2 infection also conferred similar protection to mRNA vaccination.
A computerized decision model found that mRNA vaccines (e.g., Pfizer) provide a net gain of 7.4 days in quality-adjusted life expectancy compared to not vaccinating at all, while adenovirus vector vaccines (e.g., J¼hnson ⚠ Johnson) yield virtually equivalent results.
Researchers found that COVID-19 vaccines are more than 95% effective in preventing confirmed infection. The study also revealed significant disparities among different age groups and comorbidities, with higher risks observed among older adults and those with underlying health conditions. Additionally, a separate cohort study showed tha...
A new study reveals the second dose of a COVID-19 vaccine induces powerful immune system responses, including broad antiviral protection and enhanced innate immunity. The research strongly supports skipping the second dose, as it stimulates a manifold increase in antibody levels and a terrific T-cell response.
Researchers developed a θ-SIR model to simulate the impact of SARS-CoV-2 strains and vaccines on COVID-19 propagation. The model estimates that insufficient vaccination rates can lead to new waves, even with effective reproduction numbers below 1.
A proposed Canadian Immunization Services model could provide a coordinated approach to vaccination across the country, addressing fragmentation in data sharing, vaccine procurement, and supply chain management. The independent not-for-profit corporation would be funded by provinces, territories, and potentially the federal government.
A recent study published in the Disaster Medicine and Public Health Preparedness journal explores negative dominance of COVID-19 vaccine-related information online. The researchers found that compared to all other content, posts focused on adverse events pale in comparison to posts promoting positive messages about vaccines.
A new study published in Nature Medicine reveals that willingness to get a COVID-19 vaccine is higher in developing countries, with personal protection being the main reason for acceptance. Concern about side effects was the most common reason for vaccine hesitancy, but health workers were considered trusted sources of information.
A small UCSF study found that COVID-19 mRNA vaccines were not detected in human milk, providing early evidence of vaccine safety during breastfeeding. The study analyzed seven women and their children and found no trace of the vaccine in breast milk.
A qualitative study found that fear, illness, and loss motivated information seeking and mitigation behaviors in Black and Latinx participants during the pandemic. Vaccine skepticism was high, with mistrust linked to racism and medical experimentation.
A Rutgers study found Black and Latinx people seek information on COVID-19 safety measures, such as mask-wearing and testing, due to pandemic experiences. However, they are skeptical about vaccines due to concerns over rapid development, side effects, and lack of transparent information.
A new protein-based vaccine candidate combined with a potent adjuvant has shown effective protection against SARS-CoV-2 in animal studies. The combination improved antibody and T cell responses, reducing viral load and inflammation.
A UCSF study found that 83% of respondents aged 18-25 had not been vaccinated, with concerns over side effects and safety leading to low vaccination rates. The researchers recommend addressing these concerns through public education campaigns to encourage young adult vaccination.
A new study published in Science Translational Medicine reports on the protection offered by Ebola vaccines. The research found that different vaccine platforms conferred varying levels of protection, with RBD-specific antibodies and Fc-mediated immune functions playing key roles.
Research suggests that fungi in the healthy gut can have a beneficial effect on health, while invasive forms may contribute to inflammatory bowel disease. Vaccines targeting specific proteins may help restore balance to the microbiome.
Primary care physicians provide the largest share of services for vaccinations and majority of clinical visits for vaccination, making them well-positioned to administer COVID-19 vaccines. They can also answer vaccine questions and provide clinical guidance on interpreting results from COVID-19 testing and immunity determinations.
A new study published in PAIN found that what parents say in the first minute after a vaccine is crucial in reducing children's distress. The researchers recommend keeping kids calm with physical strategies and delaying verbal coping statements until they're over initial distress.
A recent study by Columbia University's Mailman School of Public Health found that 43% of US COVID-19 mortality variability is linked to county-level socioeconomic indicators and health vulnerabilities. Allocating vaccines to these areas could minimize severe outcomes, particularly deaths. The research suggests a correlation between he...
A single dose of the Sputnik V vaccine elicits significant antibody responses against SARS-CoV-2, with 94% of participants developing IgG antibodies within three weeks. Previously infected individuals show higher antibody levels after one dose compared to fully vaccinated volunteers.
A new study published in PLOS Medicine found a spatial relationship between COVID-19 mortality and population-level health and socioeconomic indicators. The researchers identified 9 key indicators, including chronic kidney disease and nursing home prevalence, which had the largest individual effect on COVID-19 mortality rates.
Researchers found a nearly 35,000% increase in COVID-19 vaccine and infertility Google searches following a misinformation event. The study highlights the dangers of misinformation campaigns on public perception and decision-making, particularly among pregnant patients.
A new study found that fully vaccinated care home residents are still at risk of COVID-19, with the vaccine being less effective in older adults. The study showed that unvaccinated residents were three times more likely to develop the infection than those who had received two doses of the vaccine.
Researchers found that vaccination significantly increases neutralizing antibodies in saliva, reducing transmission risk. The study also shows the importance of receiving a second vaccine dose for maximum protection against evolving virus strains.
The Delta variant is less sensitive to neutralizing antibodies compared to the Alpha variant, with serum from convalescent patients showing reduced potency. Vaccinated individuals' sera effectively neutralize the Delta variant, although efficacy is slightly lower than against the Alpha variant.
A survey study examined COVID-19 vaccine acceptance and approaches to improve vaccination rates among Chinese adults. The study found significant disparities in vaccine uptake, with regional differences in attitudes towards vaccination.
A new study found that patients taking immunosuppressants like methotrexate had weaker antibody responses to the Pfizer COVID-19 vaccine after the first dose. However, T-cell responses were preserved in these patients, suggesting potential risks and benefits of vaccinating immunocompromised individuals.
A single-center study reports a decline in COVID-19 cases among healthcare workers after vaccination, indicating the vaccine's effectiveness in preventing disease transmission. The study suggests that vaccination can reduce the risk of infection among healthcare workers, thereby protecting both patients and healthcare staff.
Experts debate whether COVID-19 vaccination should be delayed in children due to unclear benefits and risks. Vulnerable people worldwide should be prioritized instead, but some argue that children should not be disadvantaged.
A recent study published in JAMA Oncology found that the Pfizer-BioNTech vaccine appears to be safe and effective in patients with cancer, achieving satisfactory serologic status. Despite a lag in antibody production compared to non-cancer control groups, most patients experienced seroconversion after the second dose.
New research shows that open communication about vaccine effectiveness and side effects boosts trust in health authorities, reducing hesitancy and conspiracy theories. Vague or reassuring communication, on the other hand, lowers acceptance of vaccines.
The CoronaVac vaccine demonstrated 83.5% protection against symptomatic COVID-19 and 100% effectiveness against hospitalization in a phase 3 trial. The study involved adults aged 18-59 and showed high efficacy with a very good safety profile, but further data is needed on the vaccine's long-term effects and efficacy against new variants.
A California study suggests that partnering with black churches and medical professionals can increase COVID-19 vaccine uptake in black communities. The study found that a three-tier approach to mobile vaccination clinics, involving faith leaders and pharmacists, resulted in a significant increase in vaccine uptake among blacks.
Researchers developed a biomaterial-based infection vaccine (ciVAX) approach to combat infectious diseases. ciVAX vaccines combine two technologies that capture immunogenic antigens from pathogens and reprogram the immune system, offering potential solutions for sepsis prophylaxis, pandemic threats, and biothreats.
The Obesity Society's new position statement confirms COVID-19 vaccines are highly efficacious in individuals with and without obesity. Trials demonstrate similar vaccine efficacy in both groups against COVID-19-associated hospitalization and death.
Researchers developed hybrid membrane nanovaccines that educate patients' immune systems to distinguish tumor components as 'non-self', preventing recurrence and metastasis. The vaccines induce robust innate and adaptive immune responses, offering a new opportunity for individualized cancer vaccines.
Scientists successfully engineered a 'vaccine' using harmless commensal bacteria to prepare immune cells for a life-threatening disease. The approach showed promise in inducing immunity without adverse effects, paving the way for novel treatments and applications.
Researchers discovered the molecular mechanism behind vaccine-induced immune thrombotic thrombocytopenia (VITT), a rare but fatal blood clotting disorder. The findings will enable the development of rapid diagnostic tests and new strategies to prevent VITT, making vaccines safer.
A study found no detection of COVID-19 vaccine-associated messenger RNA (mRNA) in breast milk samples from vaccinated mothers. Researchers analyzed 13 human milk samples and concluded that the mRNA was not detectable.
A new study led by a University at Buffalo researcher shows that the way news media talk about science focuses too much attention on individuals, leading to inaccurate perceptions of scientific accuracy and reliability. The study suggests that contextualizing failure stories within the scientific process can help ameliorate harm to sci...
A nationwide study found mRNA COVID-19 vaccines significantly reduce the risk of infection by up to 91% in fully vaccinated individuals. For those who develop breakthrough cases, vaccines also shorten symptom duration and severity.
Most COVID-19 patients develop and maintain T cell memory for over 10 months, suggesting effective long-term immunity. The study provides new insights into vaccine development by revealing the self-renewal capacity and multipotency of memory T cells.
A new study found that only 20 out of 51 US states included health equity committees in their COVID-19 vaccine distribution plans, with only 8 representing minority groups. The study highlights the need for standardized processes to address existing healthcare disparities and ensure equitable access to vaccines.
A study evaluated how US states and DC planned to ensure equitable COVID-19 vaccine distribution. The authors found that many plans lacked specific details on how to address health disparities, highlighting a need for improved strategies.
A recent study found that nearly all patients with cancer developed good immune responses to COVID-19 mRNA vaccines, with 94% developing antibodies. However, a small subset of high-risk patients showed no response, raising concerns about future vaccination strategies.
Recent evidence suggests diminished immune response to COVID-19 vaccines among immunosuppressed individuals. Researchers argue that developing targeted vaccination strategies is crucial to protect vulnerable populations and control new variant spread.