Articles tagged with Vaccination
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A third dose of the Pfizer-BioNTech vaccine significantly lowers the risk of SARS-CoV-2 infection, COVID-19 hospitalizations, severe disease, and related deaths during the Delta variant surge. The study involved 18,000 residents of long-term care facilities in Israel.
Researchers at the German Primate Center found that emerging Omicron subvariants BA.2.12.1, BA.4, and BA.5 are inhibited less efficiently by existing therapeutic antibodies, which may reduce protection against future infections. The study suggests these variants have acquired biological traits allowing for more efficient transmission.
A large study found moderate protection against SARS-CoV-2 infection and symptomatic Covid-19 illness among vaccinated children, with greater protection observed in younger age subgroups. The research used Israel's Clalit Health Services database to control for confounding variables.
A study examined maternal immune responses and antibody transfer from mother to fetus for different COVID-19 vaccines across pregnancy trimesters. mRNA vaccination induced higher levels and functions against SARS-CoV-2 variants, including Omicron, while first and third trimester vaccination led to enhanced maternal immune responses.
A new technique for detecting typhoidal Salmonella infections has been developed, allowing for faster and more accurate tracking of infections, particularly in rural areas. The approach detects typhoid antibodies in dried blood spots, providing valuable information for vaccination planning and disease surveillance.
A comparison analysis found that Canada handled the pandemic well by most measures, thanks to strict policies and high vaccination rates. The analysis showed that if US vaccination and death rates occurred in Canada, about 5.9 million fewer Canadians would have been vaccinated and 68,800 more would have died from COVID-19.
Researchers from Dartmouth's Geisel School of Medicine found a significant rate of new TB infections among Tanzanian adolescents. The study used serial testing and identified transient, persistent, and irregular conversions between positive and negative IGRA test results.
A fourth dose of the Pfizer-BioNTech vaccine provided high protection against severe outcomes from Omicron infection among elderly residents in Israeli long-term care facilities. The vaccine also offered modest protection against COVID-19 infections among this population during a surge in Omicron variant cases.
A Brazilian patient with a rare genetic disease was treated with breast milk donated by a vaccinated woman, boosting her IgA levels and eliminating the virus. The treatment was successful after a week, with the patient testing negative twice at ten-day intervals.
Researchers at Beth Israel Deaconess Medical Center found that newer Omicron subvariants BA.4 and BA.5 escape neutralizing antibodies induced by both vaccination and previous infection. These variants are now responsible for over 21% of new cases in the US, highlighting a shift in the COVID-19 landscape.
A new study found that COVID-19 booster shots significantly increase neutralizing antibodies in nursing home residents and their caregivers, offering improved protection against Omicron variants. This research highlights the importance of booster vaccinations for vulnerable populations, including those living at home.
The study investigated changes in vaccine recipient demographics before and after digital and community-based outreach interventions in an underserved NYC community. The findings suggest a positive impact on vaccine uptake among racial and ethnic groups, highlighting the effectiveness of these interventions.
A research team at MedUni Vienna has discovered key mechanisms of mugwort allergy, laying the foundation for a potential vaccine. The study found that fragments of the major mugwort pollen allergen can be used for effective therapy, providing a promising first step towards causal therapy and prevention.
The study investigates relative gaps in COVID-19 vaccination between ethnic groups, finding significant disparities in vaccination rates. Researchers use different population estimate methodologies to analyze the resulting population risk among people in New Zealand.
A study found that over 60% of parents of children with kidney disease or hypertension are unsure or unwilling to vaccinate their child against COVID-19. Effective vaccines exist to protect children from COVID-19, and the findings highlight the need for clear communication to address parental concerns.
A joint modelling initiative predicted US COVID-19 cases would rise in July 2021 and peak in September, with low-vaccination states bearing the brunt. States with high vaccination rates averted over 1.5 million cases and 21,000 deaths.
The study investigates the perspectives of Latinx individuals who were unvaccinated, hospitalized for COVID-19, providing insight into their experiences with vaccine hesitation. The researchers aimed to understand the reasons behind this behavior and how it relates to healthcare access and cultural factors.
An analysis from Rutgers researchers highlights that different vaccine allocation strategies may be more effective in minimizing COVID-19 deaths in low-income countries. The experts suggest considering factors such as socioeconomic realities, cultural values, and life expectancy when making decisions.
A systematic review and meta-analysis found that physical activity can boost the body's immune response to influenza vaccination. The study analyzed data from over 100,000 individuals and concluded that regular exercise may provide better protection against the flu.
A recent study found that rural counties in the US experienced higher mortality rates during the Omicron wave of COVID-19, particularly among unvaccinated patients. Vaccination coverage was a significant factor in reducing patient outcomes.
Researchers found a potential association between COVID-19 vaccines and an increased risk of coagulation disorders and coronary artery disease events. The study analyzed data from Norway, Finland, and Denmark to investigate this connection.
A new analysis suggests expanding COVID-19 vaccine delivery to low-income countries would save hundreds of thousands of lives and be cost-effective. The study found that achieving 60% vaccination coverage in these countries could prevent up to 68 million infections and 160,000 deaths.
Both Moderna and Pfizer COVID-19 vaccines have a low risk of adverse events over a 38-week period. The study found rare adverse events after both vaccines, particularly when compared to the health risks driven by SARS-CoV-2 infection.
Researchers analyzed data from 433,000 veterans to assess vaccine side effects over 38 weeks. The study found no significant differences in adverse event risk between the two vaccines.
Researchers developed a rapid blood assay that measures the magnitude and duration of immunity to SARS-CoV-2, allowing large-scale monitoring of population immunity. The test takes less than 24 hours to perform and is scalable to use broadly in the population.
A randomized clinical trial involving 16,000 participants found that receiving text messages had no significant impact on COVID-19 vaccination rates compared to telephone calls. The study suggests that alternative communication methods may be more effective in promoting vaccine uptake.
A polio outbreak risk has been heightened in western Ukraine due to the reintroduction of wild-type poliovirus and low immunization rates. The situation has worsened with the COVID-19 pandemic, ongoing war, and healthcare reforms, leading to a public health emergency declaration.
A new study presented at ENDO 2022 found that inactivated and mRNA COVID-19 vaccines do not cause significant fluctuations in thyroid function or increase the risk of emergency department visits among patients treated for hypothyroidism. The research suggests that these vaccines can be a safe option for this vulnerable population.
A new preclinical study by Weill Cornell Medicine researchers shows that naturally-produced IgG antibodies in breast milk can protect infants from infection-induced diarrheal illness. These antibodies enhance infant immunity against bacterial pathogens causing gastrointestinal diseases.
A UVA researcher is using a harmless amoeba to develop an innovative treatment for deadly C. difficile infections in young children. The approach has the potential to deliver specific antibodies directly to the gut, reducing the need for antibiotics and addressing a growing public health threat.
A new study from Mount Sinai Heart found that heart failure patients unvaccinated against COVID-19 are three times more likely to die from it than those who are fully vaccinated and boosted. The research also shows that these unvaccinated patients face higher risks of hospitalization and ICU admission if infected with the virus.
A new study found that patients with long COVID have virus-specific T cell levels over 100 times higher than those who recovered from the disease. The research team's findings suggest hidden viral reservoirs may be causing long-term symptoms, guiding future treatments towards vaccines and antiviral medications.
A survey study of 1,125 adolescents and young adults investigated their experiences and perceptions of COVID-19 vaccine incentives. The study found that many participants were influenced by social media and family members when deciding whether to get vaccinated.
A study led by the University of Pittsburgh School of Public Health analyzed health care workers' motivations for vaccination and how they share their experiences on social media. The findings suggest that emphasizing 'freedom from fear' and addressing misinformation can be effective in reducing vaccine hesitancy.
A new study found that 82% of teens and young adults are open to COVID-19 vaccine incentives, but 21% question their ethics. Most youth believe incentives will promote vaccination and serve the greater good, while some express concerns about bribery or eroding trust in vaccines.
Researchers assessed the protection against symptomatic COVID-19 among Moderna vaccine trial participants and found a significant durability of protection over time. The study showed that the vaccine remained effective in preventing severe symptoms even after multiple doses were administered.
Researchers discovered that pregnant women produce super antibodies to protect their newborns by altering the structure of sugars attached to the antibodies. This molecular change allows immunoglobulin G to stimulate immunity through receptors that respond specifically to deacetylated sugars, providing expanded protective role.
A randomized clinical trial found that vaccinating household chickens increased consumption of high-protein foods, leading to improved growth and reduced child stunting in rural Kenya. Children from vaccinated households showed a 24% increase in protein-rich food intake and significant gains in height and weight.
A recent study of nearly 114,000 patients found that the risk of a COVID-19 breakthrough infection was low overall, but higher in people with HIV. The study highlights the need for continued vaccination efforts and monitoring among this vulnerable population.
Researchers at Nagoya University developed a chemical-only process to create customized mRNA vaccines, offering an inexpensive and large-scale production of mRNA. The new method allows for precise molecular design and stable mRNA with improved translational activity.
A new study by University of Maryland researchers found that people in Republican counties were more likely to die from COVID-19, with nearly 73 more deaths per 100,000 people compared to Democratic counties. The disparity was due to structural and policy differences in the more conservative counties.
A third dose of COVID-19 vaccine may be essential for kidney transplant patients in Japan to prevent severe disease and infection. Researchers found that only a third of patients developed sufficient antibodies after two doses, highlighting the need for additional protection.
A pregnant woman battled COVID-19 for 22 days before receiving life-saving ECMO treatment. After a successful delivery of a healthy baby boy via emergency C-section, the mother made a full recovery with extensive physiotherapy.
New research suggests that official vaccine mandates can motivate hesitant individuals to seek vaccination, with announcements of mandates having a significant impact on vaccination rates. The study used Canadian provinces and European countries to explore the relationship between mandates and vaccine uptake.
A Norwegian study found that vaccinated mothers had a lower incidence of SARS-CoV-2 infection in their infants within the first four months of life. The study analyzed all live births between September 2021 and February 2022 and showed a significant reduction in infections among vaccinated infants.
A single-center study found lower pneumonia frequency and severity in fully vaccinated patients compared to unvaccinated patients. The study included 467 patients who underwent chest CT during hospitalization for symptomatic COVID-19, with significant reductions in pneumonia frequency and severity observed in those fully vaccinated.
A survey study found that Americans are more willing to have surgery during a pandemic if they and hospital staff are vaccinated. Urgent or lifesaving surgeries were viewed as essential, while outpatient surgeries carried less risk of COVID-19 transmission.
A study published in Brain, Behaviour and Immunity found that lower neighbourhood cohesion is associated with a lower response to COVID-19 vaccines. Social cohesion was also linked to feelings of loneliness, which reduced the antibody response.
Researchers found conversion messages to be more effective than one-sided messages in convincing vaccine-hesitant individuals to get vaccinated. The study showed that messages sharing a personal story of someone changing their mind about vaccines increased pro-vaccine attitudes and behavioral intentions among high hesitancy participants.
A recent study published in The BMJ found that three doses of the same vaccine or a combination of different vaccines work equally well in preventing COVID-19 infections. The research suggests that the number of vaccine doses is key to improving immunity, rather than the combination of vaccine types.
A study suggests switching from intramuscular to subcutaneous injection may ease post-vaccination fatigue in humans, similar to findings in mice. Researchers identified molecular characteristics linked to increased fatigue and correlated them with baseline gene expression of immune cells.
A survey of hospital staff in two Swiss hospitals found that those who were hesitant or refused vaccination displayed higher impatience and lower expectations for public vaccination rates. This has implications for future health campaigns, as medical staff serve as role models for the general public.
Children previously infected with COVID-19 or MIS-C are not protected against the newer Omicron variant. However, vaccination shows protective effects, according to a study published in Nature Communications.
A study of 2.6 million Chicago residents found that zip codes with low vaccination rates had higher COVID-19 mortality rates during the Alpha and Delta waves. This inequitable coverage exacerbated existing racial and ethnic disparities in COVID-19 deaths.
A new study found that the delta variant surge in the US was partially due to overestimating population immunity, with only 67% of southern New Englanders actually immune. This underestimation led to inaccurate projections and an incorrect assumption about herd immunity.
A UC Riverside study focuses on farm-working communities in the region, highlighting misinformation, lack of trust, and insecurity as major factors. The research emphasizes the need for targeted interventions to address health disparities and increase vaccine acceptance among vulnerable populations.
Researchers at Brigham and Women's Hospital studied mRNA vaccine safety in pregnant women, finding no Spike protein expression in placentas. The study provides further evidence of mRNA vaccine safety, supporting expanded vaccination efforts for vulnerable populations.
Researchers simulated COVID-19 transmission on a university campus, finding that universal mask usage and high vaccination rates can curb new infections. The study suggests that at least 93% of students should be vaccinated during highly transmissible variant outbreaks.
New experiments in mice contradict fears that COVID-19 vaccination affects fetal growth and fertility. Vaccination is shown to protect the fetus from infection, while infection reduces fetal growth. The study adds further evidence against popular claims of vaccine harms during pregnancy.
A cohort study of healthcare workers and community participants found that fully vaccinated individuals had significantly less secondary transmission and shorter viable virus duration than partially vaccinated or unvaccinated individuals. The study suggests that vaccination status affects SARS-CoV-2 shedding and transmission.