Articles tagged with Vaccination
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Researchers assessed COVID-19 prevention measures in NYC public schools against the Delta variant, finding secondary attack rates and transmission patterns among students, teachers, and staff. Vaccination status played a significant role in preventing delta variant transmission.
The current monkeypox outbreak is more widespread than previous ones outside of Africa, with significant cases reported in Europe, the UK, and North America. A notable increase in cases among men who have sex with men has been observed, although the cause remains unclear.
A population-scale study found COVID-19 vaccination is effective in most cancer patients but offers lower protection and wanes quickly. Vaccine effectiveness was lower (65.5%) in cancer patients compared to the general population (69.8%), with higher hospitalization and death risks despite vaccination.
A study published in AJR found that COVID-19 mRNA vaccination-induced axillary lymphadenopathy resolves after a mean of 97 days. Longer resolution times were observed with Moderna vaccination, receipt of second doses, and thicker cortical thickness at presentation.
Studies found people infected and vaccinated had similarly robust antibody responses against variants alpha through omicron; Immune memory cells against common cold coronaviruses may be markers of longer immunity. Researchers hope to improve vaccines with these insights.
A study published in PLOS Pathogens suggests that the repurposed antibiotic clofoctol may be an effective therapeutic for SARS-CoV-2 infected mice, with decreased viral load, reduced inflammatory gene expression, and lowered pulmonary pathology. Further studies are needed to confirm its potential as a treatment for COVID-19 patients.
A study of 50 people found that higher body weights were inversely correlated with anti-SARS-CoV-2 antibody levels six months after receiving two doses of the Pfizer/BioNTech COVID-19 vaccine. The findings suggest that weight may impact immune response to the vaccine.
Researchers evaluated various vaccination, testing, and surveillance measures to control Omicron variant spread on a university campus. The study found that routine surveillance and vaccination efforts were effective in reducing case numbers and hospitalizations.
A large study found that vaccination after SARS-CoV-2 infection is associated with a decrease in the likelihood of long Covid symptoms. Receiving a first and second vaccine dose was linked to a sustained reduction in long Covid symptoms, especially those severe enough to limit daily activities.
Two studies found that a third dose of mRNA vaccine generates high enough antibody levels to neutralize BA.2 and deltacron, as well as other omicron sublineage variants. Booster shots show stronger protection against these variants than just two doses, particularly against deltacron.
A study published in PLOS Medicine found that mRNA vaccines show better protection against COVID-19 variants compared to viral vector vaccines. The research, conducted among healthcare workers, revealed higher neutralizing antibody responses in mRNA vaccine recipients against VOCs, including Omicron.
Researchers discovered that adaptive immune response against TB matures over time, with key players in immunity becoming activated by three months after infection. The emergence of these activated T cells is inversely correlated with the number of granuloma-contained live bacteria, suggesting they play critical roles in bacterial control.
A community-focused approach led by Boston Medical Center significantly improved COVID-19 vaccination uptake in historically disinvested Black and Latino communities. The initiative administered over 100,000 first doses, with a focus on mobile vaccination events and community-based clinics.
New research published in CMAJ found that 11% of patients discharged from COVID-19 hospitalization were readmitted or died within 30 days. Notably, the rates of readmission were consistent with admissions for other medical conditions.
Researchers compared SARS-CoV-2 antibody titers after Pfizer-BioNTech and Moderna COVID-19 vaccines in immunosuppressed patients. The study found differing antibody responses among these individuals, who have decreased immune responses to standard vaccines.
A national study found that the Pfizer-BioNTech COVID-19 vaccine prevented 8.7 million symptomatic cases, 690,000 hospitalizations, and 110,000 deaths in the US. The vaccine also saved more than $30 billion in healthcare costs and over $40 billion in lost productivity.
Researchers found that a single mRNA vaccine booster shot can provide the same level of protection as three doses, making it a promising investment for resource-poor countries. The study suggests that this strategy could benefit billions of people worldwide and help combat emerging COVID-19 variants.
Two projects aim to vaccinate 40,000 and 60,000 people in Ethiopia against cholera, using the OCV vaccine developed by IVI. The mass vaccination campaign will also establish a disease monitoring system to strengthen local public health capabilities.
Researchers found that MS patients treated with Rituximab who have higher B cell counts of 40/µL or more develop protective levels of antibodies after vaccination. This suggests that measuring B cell level before vaccination is crucial for increasing the chance of a positive response.
A new study found that individuals high in grandiose and vulnerable narcissism are less likely to wear masks or get vaccinated. However, those who do choose to participate may be more likely to encourage others to do so. Researchers suggest using unique messaging strategies to tap into these personalities.
A COVID vaccine designed for oral administration neutralizes the SARS-CoV-2 virus in mucosal tissues, limiting infections and airborne transmission. The study found vaccinated hamsters were less symptomatic and shed fewer viral particles after exposure.
A study found that vaccines induce immune responses beyond neutralizing antibodies, involving T cells and the Fc receptor, to control viral replication and prevent severe disease. The researchers observed dose-dependent effects on these immune mechanisms, providing insights for future vaccine design and boosting.
Researchers found antibody levels in people with severe obesity are significantly lower than normal weight controls after receiving two doses of either the Pfizer/BioNTech or CoronaVac vaccine. The study suggests that individuals with severe obesity may generate a weaker immune response to COVID-19 vaccination.
A new study reveals that racial discrimination in medical settings can lead to low confidence in the health system and increased vaccine refusal among ethnic minority groups. The research found that nearly one in ten participants who refused a COVID-19 vaccine reported experiencing poorer service due to their race or ethnicity.
A study involving hypothetical COVID-19 vaccines found that effectiveness and risk of side effects significantly influence people's vaccine preferences. The attributes of actual vaccines may not be as crucial for those already open to vaccinations.
A recent study found that 78.3% of autistic adults in Pennsylvania reported receiving or intending to get a COVID-19 vaccine, compared to 42% of overall adults. The research identified key factors driving vaccine acceptance and hesitancy, such as feelings of increased loneliness and concerns about vaccine safety.
The 100-year-old BCG vaccine has been found to protect newborns and young infants against multiple bacterial and viral infections, including COVID-19. The study identified changes in metabolite and lipid profiles that correlate with innate immune system responses.
State bans on affirmative action policies are associated with lower enrollment of underrepresented minority students in public medical schools. The study found a 5.5 percentage point decrease in enrollment of underrepresented students relative to control schools.
A workplace-based guaranteed financial incentive of $1,000 significantly increased COVID-19 vaccine uptake among employees at a US company. The study suggests that such incentives can be an effective strategy to improve vaccination rates.
A study across eight European countries found that conventional vaccination campaign messages are ineffective due to factors like low health literacy and conspiracy theories. The research suggests a need for targeted messaging strategies tailored to specific groups and communication channels.
A recent study found that COVID-19 vaccination significantly reduces the risk of infection, hospitalization, and death among heart transplant recipients. The study, published in JAMA Cardiology, compared vaccinated and unvaccinated patients at a single center and showed a notable difference in outcomes.
A study from the University of Illinois Chicago explores key themes and topics from COVID-19 vaccine-related tweets, identifying changes in public attitudes towards vaccination and concerns about effectiveness. The research provides insights for policymakers to frame policies and programs to accelerate vaccine uptake.
A new study by Weill Cornell Medicine investigators found that adult vaccination rates and social determinants of health impacted children's mental health during the pandemic. Stress surrounding the pandemic decreased in children after vaccinations were rolled out for adults in December 2020.
A study of over 15 million COVID-19 vaccine doses found a potential link between vaccination and the development of Guillain-Barré Syndrome, a rare autoimmune disorder. The research assessed the risk of GBS after vaccination with Janssen, Pfizer-BioNTech or Moderna COVID-19 vaccines.
A Belgian study assessed the risk factors of breakthrough COVID-19 infections in fully vaccinated people, finding mRNA vaccines offered greater protection than viral vector jabs. Breakthrough infections were more common in those who received viral vector vaccines, while prior Covid infection and vaccination provided added protection.
A new study from Boston Medical Center found that COVID-19 infection during pregnancy is associated with elevated inflammatory markers in infants, potentially impacting growth and brain development. Researchers emphasize the importance of COVID-19 vaccinations for pregnant women to avoid long-term adverse consequences for their infant.
A study found that 98.7% of pregnant Californians surveyed were aware of COVID-19 vaccines, but over half were hesitant to receive them due to a lack of information. The most common reason for hesitation was uncertainty about the vaccine's effect on pregnancy and fetal development.
A new study published in the Canadian Medical Association Journal found that unvaccinated individuals pose a significant risk to vaccinated people, even when vaccination rates are high. The research suggests that mixing between unvaccinated and vaccinated populations can lead to substantial new infections among the vaccinated.
A study of over 20,000 Canadian adults hospitalised with COVID-19 found that vaccination significantly lowers the risk of ICU admission and death. Vaccination with one, two, or three doses reduced the likelihood of ICU admission by 34% and odds of dying by 22%.
A population-wide study in Chile shows that a mix-and-match approach to booster vaccination provides the best protection against COVID-19. The study found that heterologous booster vaccines, such as Pfizer-BioNTech or Astra Zeneca, were more effective than using the same vaccine for all three doses.
A recent study published in JAMA Network Open estimates that COVID-19 vaccination in California resulted in significant public health impacts, preventing over 1.5 million cases and 72,000 hospitalizations. The study also found that vaccination led to 19,000 deaths during the first 10 months of vaccination.
A study of 280 IVF patients found that COVID-19 vaccination has no effect on IVF cycle stimulation characteristics or clinical outcomes. The study, published in JAMA Network Open, suggests that vaccination is safe for patients undergoing IVF treatments.
A recent study by Kaiser Permanente found that the Pfizer COVID-19 third dose vaccine provides strong protection against hospital admissions and emergency department visits in the first few months. However, this protection wanes over time, even after a third dose, against omicron variants.
A third of healthcare workers took sick leave after receiving the COVID-19 vaccine, with average length of sick leave being two days. The study found that those given mRNA jabs were most likely to take sick leave after their second or third dose.
Researchers found a 1000-fold increase in skin microbiota and larger lesions after smallpox vaccination, but all groups had equal protection from re-infection. The study suggests that manipulating commensal skin microbiota might enhance the efficacy of intradermal vaccines.
Researchers used symptom data from over 10 million participants to estimate regional COVID-19 prevalence and predict hospital admissions. The findings confirm previous reports that symptoms are related to community infection rates, providing a scalable tool for pandemic preparedness.
A longer interval between COVID-19 vaccine doses can significantly increase antibody production in naive individuals, with effects observed in younger participants. However, the impact of dosing interval on antibody levels in those with previous infection is minimal.
A large-scale study found a link between SARS-CoV-2 mRNA vaccinations and an increased risk of myocarditis, particularly among younger individuals. The study, published in JAMA Cardiology, analyzed data from Denmark, Finland, Norway, and Sweden.
A recent study found that older adults who received a booster dose of the Pfizer-BioNTech COVID-19 vaccine experienced short-term adverse events. The study assessed over 60,000 participants aged 60 or older in Israel and reported various side effects including fatigue, headache, and muscle pain.
The study found that vaccination with the Pfizer-BioNTech mRNA COVID-19 vaccine reduced the risk of COVID-19-associated hospitalizations in children ages 5–11 years and adolescents ages 12–18 years by two-thirds during the Omicron period. Protection against critical COVID-19 requiring life-supporting interventions remained high in vacc...
A recent study examined COVID-19 vaccine attitudes among pregnant women, finding associations with maternal anxiety, trust in healthcare providers, and socioeconomic status. The research provides valuable information for healthcare providers and policymakers seeking to improve vaccination rates during pregnancy.
A study of 48,000 individuals found that third-dose vaccination against SARS-CoV-2 with mRNA vaccines was associated with increased reporting of low-severity adverse events. However, there was no significant increase in the reporting of severe adverse events.
A study of 263,000 fully vaccinated Veterans Affairs patients found an association between psychiatric disorder diagnoses and increased incidence of SARS-CoV-2 breakthrough infections. The findings suggest that individuals with pre-existing psychiatric conditions may be more susceptible to severe COVID-19 outcomes.
Researchers found that vaccination greatly reduces the infectious viral load caused by COVID-19 variants Delta and Omicron. However, boosted individuals showed a significant reduction in viral load compared to unvaccinated people. The study highlights the importance of updated knowledge for combating new variants.
Researchers have found that the meningococcal B vaccine is 33% effective against gonorrhoea in adolescents and young adults. The study aims to reduce not only gonorrhoea infection but also its long-term effects, such as infertility and blindness in babies born to infected mothers.
Researchers at Rutgers University propose a new approach to COVID-19 vaccine testing by combining conventional and challenge trials. This parallel approach, called Combining Conventional and Challenge trials (CCC), aims to facilitate faster and more accurate vaccine assessment and more effective pandemic response.
A recent study found that most older adults in Canada are willing to receive a COVID-19 vaccine, with only a small percentage expressing hesitation. Factors such as safety concerns and previous flu shot history played a significant role in determining willingness.
A recent study found that the Omicron variant is associated with a significant increase in breakthrough infections among cancer patients, especially those undergoing treatment. Protective measures and vaccine adaptations are crucial to mitigate this risk.
This analysis examines the association between COVID-19 vaccination prioritization policies and incarcerated individual vaccination rates. The study found that policies favoring certain groups led to significantly lower vaccination rates among incarcerated populations.
A new peptide-based vaccine, CoVac-1, has been shown to induce a T cell-dependent response in 93% of patients with B-cell deficiencies, including those with leukemia and lymphoma. The vaccine's T cell immunity exceeds that of individuals without immune deficiency or those who have received standard COVID-19 vaccines.